Publications
Behrens, J. ; Fuh, M.M. ; Haas, D. ; Jaeckstein, M.Y. ; Heine, M. ; Siebels, B. ; Worthmann, A. ; Krahmer, N. ; Heeren, J. ; Scheja, L.
Fructose uptake by brown adipose tissue is independent of carbohydrate response element-binding protein and does not cause elevated de novo lipogenesis.Müller, T.D.
Advances in incretin-based drug discovery in 2025.Novikoff, A. ; Müller, T.D.
One small molecule for man, one giant leap for mankind with obesity.Haas, D. ; Weindl, D. ; Kakimoto, P. ; Trautmann, E.-M. ; Schessner, J.P. ; Mao, X. ; Gerl, M.J. ; Gerwien, M. ; Müller, T.D. ; Klose, C. ; Cheng, X. ; Hasenauer, J. ; Krahmer, N.
C-COMPASS: A user-friendly neural network tool profiles cell compartments at protein and lipid levels.Molenaar, A. ; Mallet, N. ; Bralo, M. ; Höher, L. ; Schriever, S.C. ; Pathak, E. ; Bernecker, M. ; Müller, T.D. ; Ertürk, A. ; Cebrian Serrano, A. ; Pfluger, P.T.
A novel tamoxifen-inducible Mct8-CreERT2 mouse model for targeted studies of Mct8-expressing cells and thyroid hormone transport and function.Basu, A. ; Farsam, V. ; Singh, K. ; Crisan, D. ; Treiber, N. ; Schneider, L.A. ; Huber, M. ; Engelmeyer, J.I. ; Schumacher, B. ; Maity, P. ; Brandt, D. ; Jastroch, M. ; Mauch, C. ; Geiger, H. ; Kletsas, D. ; Scharffetter-Kochanek, K.
Senescent fibroblasts drive melanoma progression through GCP-2 induced CREB phosphorylation enhancing glycolysis.Ziegler, A.-G. ; Achenbach, P. ; Weiss, A. ; Berner, R. ; Casteels, K. ; Larsson, H.E. ; Haupt, F. ; Hommel, A. ; Jacobs, A. ; Kordonouri, O. ; Lundgren, M. ; Ołtarzewski, M. ; Pfirrmann, M. ; Snape, M.D. ; Szypowska, A. ; Todd, J.A. ; Vatish, M. ; Berge, T.V.D. ; Winkler, C. ; Bonifacio, E.
Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): A European, randomised, placebo-controlled, primary prevention trial.Krahmer, N. ; Walther, T.C. ; Farese, R.V.
The pathogenesis of hepatic steatosis in MASLD: A lipid droplet perspective.Harrison, L. ; Schriever, S.C. ; Bernecker, M. ; Mallet, N. ; Mencias Castillejo, C. ; Ameli, H. ; Baumann, P. ; Contreras, R. ; Stolz, J. ; Lindner, R. ; Bartzsch, S. ; Schmid, T.E. ; Combs, S.E. ; Rosemann, M. ; Pfluger, P.T.
Low-to-moderate dosed cranial irradiation in young mice induces sex-specific metabolic disturbances later in life.Altun, I. ; Vo, K.H.D. ; Walia, S.R. ; Yan, X. ; Singh, I. ; Karlina, R. ; Miok, V. ; Kang, L. ; Reichenbach, V.K. ; Israel, A. ; Lutter, D. ; Perocchi, F. ; Ussar, S.
Igf2 regulates early postnatal DPP4+ preadipocyte pool expansion.Mishra, M. ; Agrawal, S. ; Mishra, S.P. ; Kumar, R. ; Mishra, K. ; Pathak, E. ; Mishra, R.
Unveiling the molecular mechanisms of hemorrhagic shock and acute lung injury: An integrative RNA-seq and network analysis.Tejada Lapuerta, A. ; Schaar, A. ; Gutgesell, R.M. ; Palla, G. ; Halle, L. ; Minaeva, M. ; Vornholz, L. ; Dony, L. ; Drummer, F. ; Richter, T. ; Bahrami, M. ; Theis, F.J.
Nicheformer: A foundation model for single-cell and spatial omics.Rajcsanyi, L.S. ; Schmidt, J.A. ; Novikoff, A. ; Coupland, C. ; Hagemann, T. ; Hoffmann, A. ; Derksen, C. ; Beck, M. ; Bohne, N. ; Volckmar, A. ; Zheng, Y. ; Peters, T. ; Hebebrand, J. ; Blüher, M. ; Müller, T.D. ; Hinney, A.
Genetische Varianten im GLP1-R-Gen und ihre geschlechtsspezifische Bedeutung bei Adipositas.Schreier, P.C.F. ; Beyerle, P. ; Boulassel, S. ; Beck, A. ; Novikoff, A. ; Reinach, P.S. ; Boekhoff, I. ; Breit, A. ; Neuberger, A. ; Müller, T.D. ; Cebrian Serrano, A. ; Gudermann, T. ; Khajavi, N.
GLP-1/GIP/GCG receptor triagonist (IUB447) enhances insulin secretion via GLP-1 receptor and Gαq signalling pathway in mice.Le Thuc, O. ; Lechner, F. ; García-Cáceres, C.
Hypothalamic astrocytes: Connecting brain and periphery in metabolic control.Loipfinger, S. ; Grosholz, M. ; Kumar, S. ; Erbilir, H. ; Dyar, K.A. ; Müller, T.D. ; Grein, S. ; Rozman, J. ; Klingenspor, M. ; Meyer, C. ; Lutter, D.
Calopy - an advanced framework for the integration and analysis of indirect calorimetry data.Singh, I. ; Onogi, Y. ; Cardoso Micu Menezes, F.M. ; Khasanova, D. ; Kang, L. ; Wang, C. ; Ruiz-Trave, J. ; Sharma, S. ; Khalil, A. ; Reichenbach, V.K. ; Shi, Y. ; Flatley, A. ; Yan, X. ; Israel, A. ; Dragano, N.R.V. ; Aguilar-Pimentel, J.A. ; Hoffmann, A. ; Ghosh, A. ; Noé, F. ; Wolfrum, C. ; Cucuruz, S. ; König, A.-C. ; Burtscher, I. ; Hauck, S.M. ; Lickert, H. ; Hofmann, S.M. ; Feederle, R. ; Schriever, S.C. ; Hernandez-Bautista, R. ; Sancar, G. ; Cebrian Serrano, A. ; Tetko, I.V. ; Fuchs, H. ; Gailus-Durner, V. ; Blüher, M. ; Hrabě de Angelis, M. ; Ussar, S.
NRAC controls CD36-mediated fatty acid uptake in adipocytes and lipid clearance in vivo.Banks, A.S. ; Allison, D.B. ; Alquier, T. ; Ansarullah ; Austad, S.N. ; Auwerx, J. ; Ayala, J.E. ; Baur, J.A. ; Carobbio, S. ; Churchill, G.A. ; Dall, M. ; de Cabo, R. ; Donato, J. ; Dragano, N.R.V. ; Elias, C.F. ; Ferrante, A.W. ; Finck, B.N. ; Galgani, J.E. ; Gerhart-Hines, Z. ; Goodyear, L.J. ; Grobe, J.L. ; Gupta, R.K. ; Habegger, K.M. ; Hartig, S.M. ; Hevener, A.L. ; Heymsfield, S.B. ; Holman, C.D. ; Hrabě de Angelis, M. ; James, D.E. ; Kazak, L. ; Kim, J.B. ; Klingenspor, M. ; Kong, X. ; Kooijman, S. ; Lantier, L. ; Lloyd, K.C.K. ; Lo, J.C. ; Lodhi, I.J. ; MacLean, P.S. ; McGuinness, O.P. ; Medina-Gomez, G. ; Mirmira, R.G. ; Morrison, C.D. ; Morton, G.J. ; Müller, T.D. ; Ogawa, Y. ; Pajuelo-Reguera, D. ; Potthoff, M.J. ; Qi, N. ; Reitman, M.L. ; Rensen, P.C.N. ; Rozman, J. ; Rutkowsky, J.M. ; Sakamoto, K. ; Scherer, P.E. ; Schwartz, G.J. ; Sedlacek, R. ; Selloum, M. ; Shaikh, S.R. ; Chen, S. ; Shulman, G.I. ; Škop, V. ; Soukas, A.A. ; Speakman, J.R. ; Spiegelman, B.M. ; Steinberg, G.R. ; Svensson, K.J. ; Thyfault, J.P. ; Tiganis, T. ; Titchenell, P.M. ; Turner, N. ; Velloso, L.A. ; Vidal-Puig, A. ; Ward, C.S. ; Williams, A.S. ; Wolfrum, C. ; Xu, A.W. ; Xu, Y. ; Zierath, J.R.
A consensus guide to preclinical indirect calorimetry experiments.Alevyzaki, A. ; Markova, B. ; de Angelis, M. ; Müller, T.D. ; Chandrasekar, A. ; Müller-Fielitz, H. ; Schwaninger, M. ; Boelen, A. ; Führer, D. ; Mayerl, S. ; Heuer, H.
Inactivation of thyroid hormone transporters Mct8/Oatp1c1 in mouse brain endothelial cells causes region-specific alterations in central thyroid hormone signaling.Novikoff, A. ; Müller, T.D.
Tirzepatide differentially affects body weight in mice and humans.De Backer, J.F. ; Karges, T. ; Papst, J. ; Pınar, Z.N. ; Coman, C. ; Ahrends, R. ; Xu, Y. ; García-Cáceres, C. ; Grunwald Kadow, I.C.
Adenosine signaling in glia modulates metabolic state-dependent behavior in Drosophila.Gutgesell, R.M. ; Khalil, A. ; Liskiewicz, A. ; Maity-Kumar, G. ; Novikoff, A. ; Grandl, G. ; Liskiewicz, D. ; Coupland, C. ; Karaoglu, Ö.E. ; Akindehin, S.E. ; Castelino, R.L. ; Curion, F. ; Liu, X. ; García-Cáceres, C. ; Cebrian Serrano, A. ; Douros, J.D. ; Knerr, P.J. ; Finan, B. ; DiMarchi, R.D. ; Sloop, K.W. ; Samms, R.J. ; Theis, F.J. ; Tschöp, M.H. ; Müller, T.D.
Publisher Correction: GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice.Boulassel, S. ; Schreier, P.C.F. ; Melyshi, A.M. ; Berger, J. ; Reinach, P.S. ; Jacob, K. ; Boekhoff, I. ; Breit, A. ; Müller, T.D. ; Zierler, S. ; Gudermann, T. ; Khajavi, N.
Mg2+ supplementation mitigates metabolic deficits associated with TRPM7 disruption.Gutgesell, R.M. ; Khalil, A. ; Liskiewicz, A. ; Maity-Kumar, G. ; Novikoff, A. ; Grandl, G. ; Liskiewicz, D. ; Coupland, C. ; Karaoglu, Ö.E. ; Akindehin, S.E. ; Castelino, R.L. ; Curion, F. ; Liu, X. ; García-Cáceres, C. ; Cebrian Serrano, A. ; Douros, J.D. ; Knerr, P.J. ; Finan, B. ; DiMarchi, R.D. ; Sloop, K.W. ; Samms, R.J. ; Theis, F.J. ; Tschöp, M.H. ; Müller, T.D.
GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice.Shafaghat, Z. ; Radmehr, S. ; Saharkhiz, S. ; Khosrozadeh, A. ; Feiz, K. ; Alkhathami, A.G. ; Taheripak, G. ; Ramezani Farani, M. ; Rahmati, R. ; Zarimeidani, F. ; Bassereh, H. ; Bakhtiyari, S. ; Alipourfard, I.
Circular RNA, a molecule with potential chemistry and applications in RNA-based cancer therapeutics: An insight into recent advances.Prudente de Mello, N. ; Berger, M. ; Lagerborg, K.A. ; Yan, Y. ; Wettmarshausen, J. ; Keipert, S. ; Weidner, L. ; Tokarz, J. ; Möller, G. ; Ciciliot, S. ; Walia, S.R. ; Cheng, Y. ; Chudenkova, M. ; Artati, A. ; Weisenhorn, D.M. ; Wurst, W. ; Adamski, J. ; Nilsson, R.H. ; Cossu, G. ; Boon, A.J.W. ; Kievit, A.J.A. ; Mandemakers, W. ; Bonifati, V. ; Jain, M. ; Jastroch, M. ; Schmitt-Kopplin, P. ; Perocchi, F. ; Dyar, K.A.
Pervasive glycative stress links metabolic imbalance and muscle atrophy in early-onset Parkinson's disease.Coupland, C. ; Sun, N. ; Khalil, A. ; Karaoglu, Ö.E. ; Liskiewicz, A. ; Liskiewicz, D. ; Grandl, G. ; Akindehin, S.E. ; Maity-Kumar, G. ; Yang, B. ; Finan, B. ; Knerr, P.J. ; Douros, J.D. ; Walch, A.K. ; DiMarchi, R. ; Tschöp, M.H. ; Müller, T.D. ; Novikoff, A.
Estrogenic activity of E2-conjugated GLP-1 is mediated by intracellular endolysosomal acidification and estrone metabolism.Freibothe, I. ; Müller, T.D.
Inkretine als Grundlage der Adipositastherapie.Scherer, T. ; Metz, M. ; Beghini, M. ; Bilban, M. ; Gensthaler, L. ; Luca, A.C. ; Kaplanian, M. ; Abu Eid, S. ; Koldyka, O. ; Hackl, M.T. ; Dürr, S. ; Rivelles, E. ; Schönecker, S.S. ; Pöltl, L. ; Kaya, A. ; Chami, R. ; Nusko, L. ; Tschare, C. ; Ablaza, K. ; Höbler, A.L. ; Klimek, P. ; Leutner, M. ; Yamamoto, M. ; Suzuki, N. ; Stemmer, K. ; Zeyda, M. ; Steinacher, D. ; Nics, L. ; Müller, A.M.S. ; Helbich, T.H. ; Moriggl, R. ; Kautzky-Willer, A. ; Windberger, U. ; Prager, G. ; Fürnsinn, C.
A direct effect of the hematocrit on blood glucose: Evidence from hypoxia- and erythropoietin-treated mice.D'Angelo, D. ; Sánchez-Vázquez, V.H. ; Cartes-Saavedra, B. ; Vecellio Reane, D. ; Cupo, R.R. ; Delgado De La Herran, H.C. ; Ghirardo, G. ; Shorter, J. ; Wevers, R.A. ; Wortmann, S.B. ; Perocchi, F. ; Rizzuto, R. ; Raffaello, A. ; Hajnóczky, G.
Dependence of mitochondrial calcium signalling and dynamics on the disaggregase, CLPB.Douros, J.D. ; Novikoff, A. ; Dubois, B. ; Rohlfs, R. ; Mokrosiński, J. ; Hogendorf, W.F.J. ; Augustin, R. ; Merkestein, M. ; Egaa Martini, L.B. ; Linderoth, L. ; Gerrard, E. ; Kodra, J.T. ; Norlin, J. ; Roed, N.K. ; Oldenburger, A. ; Mowery, S.A. ; Waldhoer, M. ; Perez-Tilve, D. ; Finan, B. ; Reedtz-Runge, S. ; Müller, T.D. ; Knerr, P.J.
A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice.Becker, M. ; Kälin, S. ; Neubig, A.H. ; Lauber, M. ; Opaleva, D. ; Hipp, H. ; Salb, V.K. ; Ott, V. ; Legutko, B. ; Kälin, R.E. ; Hippich, M. ; Scherm, M.G. ; Nascimento, L.F.R. ; Serr, I. ; Hosp, F. ; Nikolaev, A. ; Mohebiany, A. ; Krueger, M. ; Flachmeyer, B. ; Pfaffl, M.W. ; Haase, B. ; Yi, C.X. ; Dietzen, S. ; Bopp, T. ; Woods, S.C. ; Waisman, A. ; Weigmann, B. ; Mann, M. ; Tschöp, M.H. ; Daniel, C.
Regulatory T cells in the mouse hypothalamus control immune activation and ameliorate metabolic impairments in high-calorie environments.Finan, B. ; Douros, J.D. ; Goldwater, R. ; Hansen, A.M.K. ; Hjerpsted, J.B. ; Hjøllund, K.R. ; Kankam, M.K. ; Knerr, P.J. ; Konkar, A. ; Mowery, S.A. ; Müller, T.D. ; Nielsen, J.R. ; Nygård, S.B. ; Perez-Tilve, D. ; Raun, K. ; Yang, B. ; Tschöp, M.H. ; DiMarchi, R.D.
A once-daily GLP-1/GIP/glucagon receptor tri-agonist (NN1706) lowers body weight in rodents, monkeys and humans.Ribas Latre, A. ; Hoffmann, A. ; Gebhardt, C. ; Weiner, J. ; Arndt, L. ; Raulien, N. ; Gericke, M. ; Ghosh, A. ; Krause, K. ; Klöting, N. ; Pfluger, P.T. ; Sheikh, B. ; Ebert, T. ; Tönjes, A. ; Stumvoll, M. ; Wolfrum, C. ; Blüher, M. ; Wagner, U. ; Vendrell, J. ; Fernández-Veledo, S. ; Heiker, J.T.
The serine protease KLK7 promotes immune cell infiltration in visceral adipose tissue in obesity.Nicolaisen, T.S. ; Lyster, A.E. ; Sjøberg, K.A. ; Haas, D. ; Lundsgaard, A.M. ; Jensen, J.K. ; Madsen, E.M. ; Nielsen, C.K. ; Bloch-Ibenfeldt, M. ; Wewer Albrechtsen, N.J. ; Rose, A.J. ; Krahmer, N. ; Clemmensen, C. ; Richter, E.A. ; Fritzen, A.M. ; Kiens, B.
Dietary protein restriction elevates FGF21 levels and energy requirements to maintain body weight in lean men.Müller, T.D. ; Adriaenssens, A. ; Ahrén, B. ; Blüher, M. ; Birkenfeld, A.L. ; Campbell, J.E. ; Coghlan, M.P. ; D'Alessio, D. ; Deacon, C.F. ; DelPrato, S. ; Douros, J.D. ; Drucker, D.J. ; Figueredo Burgos, N.S. ; Flatt, P.R. ; Finan, B. ; Gimeno, R.E. ; Gribble, F.M. ; Hayes, M.R. ; Hölscher, C. ; Holst, J.J. ; Knerr, P.J. ; Knop, F.K. ; Kusminski, C.M. ; Liskiewicz, A. ; Mabilleau, G. ; Mowery, S.A. ; Nauck, M.A. ; Novikoff, A. ; Reimann, F. ; Roberts, A.G. ; Rosenkilde, M.M. ; Samms, R.J. ; Scherer, P.E. ; Seeley, R.J. ; Sloop, K.W. ; Wolfrum, C. ; Wootten, D. ; DiMarchi, R.D. ; Tschöp, M.H.
Glucose-dependent insulinotropic polypeptide (GIP).Mishra, V.K. ; Agrawal, S. ; Malik, D. ; Mishra, D. ; Bhavya, B. ; Pathak, E. ; Mishra, R.
Targeting Matrix Metalloproteinase-1, Matrix Metalloproteinase-7, and Serine Protease Inhibitor E1: Implications in preserving lung vascular endothelial integrity and immune modulation in COVID-19.Zhong, J. ; Zareifi, D. ; Weinbrenner, S. ; Hansen, M. ; Klingelhuber, F. ; Nono Nankam, P.A. ; Frendo-Cumbo, S. ; Bhalla, N. ; Cordeddu, L. ; De Castro Barbosa, T. ; Arner, P. ; Dahlman, I. ; Muniandy, M. ; Heinonen, S. ; Pietiläinen, K.H. ; Hoffmann, A. ; Ghosh, A. ; John, D. ; Tönjes, A. ; Ståhl, P.L. ; Böttcher, Y. ; Keller, M. ; Kovacs, P. ; Kerr, A.G. ; Langin, D. ; Wolfrum, C. ; Blüher, M. ; Krahmer, N. ; Massier, L. ; Mejhert, N. ; Rydén, M.
adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue.Fischer, A. ; Han, W. ; Hu, S. ; Mück-Häusl, M. ; Wannemacher, J. ; Kadri, S. ; Lin, Y. ; Dai, R. ; Christ, S. ; Su, Y. ; Dasgupta, B. ; Sardogan, A. ; Deisenhofer, C. ; Dutta, S. ; Kadri, A. ; Güney, T.G. ; Correa-Gallegos, D. ; Mayr, C.H. ; Hatz, R. ; Stoleriu, M.G. ; Lindner, M. ; Hilgendorff, A. ; Adler, H. ; Machens, H.G. ; Schiller, H.B. ; Hauck, S.M. ; Rinkevich, Y.
Author Correction: Targeting pleuro-alveolar junctions reverses lung fibrosis in mice.Pertici, I. ; D'Angelo, D. ; Vecellio Reane, D. ; Reconditi, M. ; Morotti, I. ; Putignano, E. ; Napoli, D. ; Rastelli, G. ; Gherardi, G. ; De Mario, A. ; Rizzuto, R. ; Boncompagni, S. ; Baroncelli, L. ; Linari, M. ; Caremani, M. ; Raffaello, A.
Creatine transporter (SLC6A8) knockout mice exhibit reduced muscle performance, disrupted mitochondrial Ca2+ homeostasis, and severe muscle atrophy.Fischer, A. ; Han, W. ; Hu, S. ; Mück-Häusl, M. ; Wannemacher, J. ; Kadri, S. ; Lin, Y. ; Dai, R. ; Christ, S. ; Su, Y. ; Dasgupta, B. ; Sardogan, A. ; Deisenhofer, C. ; Dutta, S. ; Kadri, A. ; Güney, T.G. ; Correa-Gallegos, D. ; Mayr, C.H. ; Hatz, R. ; Stoleriu, M.G. ; Lindner, M. ; Hilgendorff, A. ; Adler, H. ; Machens, H.G. ; Schiller, H.B. ; Hauck, S.M. ; Rinkevich, Y.
Targeting pleuro-alveolar junctions reverses lung fibrosis in mice.Forst, T. ; de Block, C. ; Del Prato, S. ; Frias, J. ; Lautenbach, A. ; Ludvik, B. ; Marinez, M. ; Mathieu, C. ; Müller, T.D. ; Schnell, O.
Novel pharmacotherapies for weight loss: Understanding the role of incretins to enable weight loss and improved health outcomes.Chen, X.W. ; Don, A.S. ; Fedorova, M. ; Harayama, T. ; Krahmer, N. ; Nagata, S. ; Narayan, P. ; Nicholas, D. ; Nowinski, S.M. ; Saheki, Y. ; Semenkovich, C.F. ; Zhao, X. ; Zou, Y.
Time for lipid cell biology.Rubino, F. ; Cummings, D.E. ; Eckel, R.H. ; Cohen, R.V. ; Wilding, J.P.H. ; Brown, W.A. ; Stanford, F.C. ; Batterham, R.L. ; Farooqi, I.S. ; Farpour-Lambert, N.J. ; le Roux, C.W. ; Sattar, N. ; Baur, L.A. ; Morrison, K.M. ; Misra, A. ; Kadowaki, T. ; Tham, K.W. ; Sumithran, P. ; Garvey, W.T. ; Kirwan, J.P. ; Fernández-Real, J.M. ; Corkey, B.E. ; Toplak, H. ; Kokkinos, A. ; Kushner, R.F. ; Branca, F. ; Valabhji, J. ; Blüher, M. ; Bornstein, S.R. ; Grill, H.J. ; Ravussin, E. ; Gregg, E.W. ; Al Busaidi, N.B. ; Alfaris, N.F. ; Al Ozairi, E. ; Carlsson, L.M.S. ; Clément, K. ; Després, J.P. ; Dixon, J.B. ; Galea, G. ; Kaplan, L.M. ; Laferrère, B. ; Laville, M. ; Lim, S. ; Luna Fuentes, J.R. ; Mooney, V.M. ; Nadglowski, J. ; Urudinachi, A. ; Olszanecka-Glinianowicz, M. ; Pan, A. ; Pattou, F. ; Schauer, P.R. ; Tschöp, M.H. ; van der Merwe, M.T. ; Vettor, R. ; Mingrone, G.
Definition and diagnostic criteria of clinical obesity.Bernecker, M. ; Lin, A. ; Feuchtinger, A. ; Molenaar, A. ; Schriever, S.C. ; Pfluger, P.T.
Weight cycling exacerbates glucose intolerance and hepatic triglyceride storage in mice with a history of chronic high fat diet exposure.Miranda-Cervantes, A. ; Fritzen, A.M. ; Raun, S.H. ; Hodek, O. ; Møller, L.L.V. ; Johann, K. ; Deisen, L. ; Gregorevic, P. ; Gudiksen, A. ; Artati, A. ; Adamski, J. ; Andersen, N.R. ; Sigvardsen, C.M. ; Carl, C.S. ; Voldstedlund, C.T. ; Kjøbsted, R. ; Hauck, S.M. ; Schjerling, P. ; Jensen, T.E. ; Cebrian Serrano, A. ; Jähnert, M. ; Gottmann, P. ; Burtscher, I. ; Lickert, H. ; Pilegaard, H. ; Schürmann, A. ; Tschöp, M.H. ; Moritz, T. ; Müller, T.D. ; Sylow, L. ; Kiens, B. ; Richter, E.A. ; Kleinert, M.
Pantothenate kinase 4 controls skeletal muscle substrate metabolism.Lorza-Gil, E. ; Strauss, O. ; Ziegler, E. ; Kansy, K. ; Katschke, M.-T. ; Rahimi, G. ; Neuscheler, D. ; Sandforth, L. ; Sandforth, A. ; Sancar, G. ; Kaufmann, B. ; Hartmann, D. ; Singer, S.R. ; Mihaljevic, A.L. ; Jumpertz von Schwartzenberg, R. ; Sbierski-Kind, J. ; Müller, T.D. ; Birkenfeld, A.L. ; Gerst, F.
Incretin-responsive human pancreatic adipose tissue organoids: A functional model for fatty pancreas research.Novikoff, A. ; Grandl, G. ; Liu, X. ; Müller, T.D.
Why are we still in need for novel anti-obesity medications?Freire-Agulleiro, Ó. ; Estévez-Salguero, Á. ; Ferreira, V. ; Holleman, C.L. ; García-Currás, J. ; González-García, I. ; Nogueiras, R. ; Tena-Sempere, M. ; García-Cáceres, C. ; Diéguez, C. ; López, M.
SF1-specific deletion of the energy sensor AMPKγ2 induces obesity.García-Cáceres, C.
Advances in appetite regulation by the arcuate nucleus.Rong, Z. ; Mai, H. ; Ebert, G. ; Kapoor, S. ; Puelles, V.G. ; Czogalla, J. ; Hu, S. ; Su, J. ; Prtvar, D. ; Singh, I. ; Schädler, J. ; Delbridge, C. ; Steinke, H. ; Frenzel, H. ; Schmidt, K. ; Braun, C. ; Bruch, G. ; Ruf, V. ; Ali, M. ; Sühs, K.W. ; Nemati, M. ; Hopfner, F. ; Ulukaya, S. ; Jeridi, D. ; Mistretta, D. ; Caliskan, Ö.S. ; Wettengel, J.M. ; Cherif, F. ; Kolabas, Z.I. ; Molbay, M. ; Horvath, I. ; Zhao, S. ; Krahmer, N. ; Yildirim, A.Ö. ; Ussar, S. ; Herms, J. ; Huber, T.B. ; Tahirovic, S. ; Schwarzmaier, S.M. ; Plesnila, N. ; Höglinger, G. ; Ondruschka, B. ; Bechmann, I. ; Protzer, U. ; Elsner, M. ; Bhatia, H.S. ; Hellal, F. ; Ertürk, A.
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19.Giuranna, J. ; Zheng, Y. ; Brandt, M. ; Jall, S. ; Mukherjee, A. ; Shankhwar, S. ; Renner, S. ; Kurapati, N.K. ; May, C. ; Peters, T. ; Herpertz-Dahlmann, B. ; Seitz, J. ; de Zwaan, M. ; Herzog, W. ; Ehrlich, S. ; Zipfel, S. ; Giel, K. ; Egberts, K. ; Burghardt, R. ; Foecker, M. ; Marcus, K. ; Keyvani, K. ; Müller, T.D. ; Schmitz, F. ; Rajcsanyi, L.S. ; Hinney, A.
Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulation.Zhao, S. ; Veit, R. ; Semeia, L. ; Hummel, J. ; Sandforth, L. ; Fritsche, A. ; Birkenfeld, A.L. ; Heni, M. ; Preissl, H. ; Kullmann, S.
Sex differences in insulin induced hippocampus functional connectivity during visual food cue presentation.Da Silva Lima, N. ; Cabaleiro, A. ; Novoa, E. ; Riobello, C. ; Knerr, P.J. ; He, Y. ; Esquinas-Román, E.M. ; González-García, I. ; Prévot, V. ; Schwaninger, M. ; Dieguez, C. ; López, M. ; Müller, T.D. ; Varela-Rey, M. ; Douros, J.D. ; Nogueiras, R.
GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells.Grandl, G. ; Novikoff, A. ; Liu, X. ; Müller, T.D.
Recent achievements and future directions of anti-obesity medications.Wagner, R. ; Buettner, J. ; Heni, M. ; Fritsche, L. ; Kullmann, S. ; Wagmüller, M. ; Peter, A. ; Preissl, H. ; Machann, J. ; Jumpertz von Schwartzenberg, R. ; Birkenfeld, A.L. ; Pape, U.F. ; van Hall, G. ; Plomgaard, P. ; Häring, H.-U. ; Fritsche, A. ; Thompson, K.N. ; Klein, R. ; Stefan, N.
Carrageenan and insulin resistance in humans: A randomised double-blind cross-over trial.Plaza-Díaz, J. ; Ruiz Ojeda, F.J. ; López-Plaza, B. ; Brandimonte-Hernández, M. ; Álvarez-Mercado, A.I. ; Arcos-Castellanos, L. ; Feliú-Batlle, J. ; Hummel, T. ; Palma-Milla, S. ; Gil, A.
Effect of a novel food rich in miraculin on the oral microbiome of malnourished oncologic patients with dysgeusia.Ofoghi, A. ; Kotschi, S. ; Lemmer, I.L. ; Haas, D. ; Willemsen, N. ; Bayer, B. ; Jung, A.S. ; Möller, S. ; Haberecht-Müller, S. ; Krüger, E. ; Krahmer, N. ; Bartelt, A.
Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis.Sanchez-Garrido, M.A. ; Serrano-López, V. ; Ruiz-Pino, F. ; Vázquez, M.J. ; Rodríguez-Martín, A. ; Torres, E. ; Velasco, I. ; Rodríguez, A.B. ; Chicano-Gálvez, E. ; Mora-Ortiz, M. ; Ohlsson, C. ; Poutanen, M. ; Pinilla, L. ; Gaytán, F. ; Douros, J.D. ; Yang, B. ; Müller, T.D. ; DiMarchi, R.D. ; Tschöp, M.H. ; Finan, B. ; Tena-Sempere, M.
Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy.Chen, B. ; Yu, X. ; Horvath-Diano, C. ; Ortuño, M.J. ; Tschöp, M.H. ; Jastreboff, A.M. ; Schneeberger, M.
GLP-1 programs the neurovascular landscape.Müller, G. ; Müller, T.D.
A "poly-matter network" conception of biological inheritance.Delgado De La Herran, H.C. ; Vecellio Reane, D. ; Cheng, Y. ; Katona, M. ; Hosp, F. ; Greotti, E. ; Wettmarshausen, J. ; Patron, M. ; Mohr, H. ; Prudente de Mello, N. ; Chudenkova, M. ; Gorza, M. ; Walia, S.R. ; Feng, M. ; Leimpek, A. ; Mielenz, D. ; Pellegata, N.S. ; Langer, T. ; Hajnoczky, G. ; Mann, M. ; Murgia, M. ; Perocchi, F.
Systematic mapping of mitochondrial calcium uniporter channel (MCUC)-mediated calcium signaling networks.Zarpellon, P.S. ; De Bernardis Murat, C. ; Leão, R.M.
Reduction in mitochondrial ATP synthesis mimics the effect of low glucose in depolarizing neurons from the subpostremal nucleus of the solitary tract of rats.Yuzbashian, E. ; Fernando, D.N. ; Ussar, S. ; Chan, C.B.
Differential effects of milk, yogurt, and cheese on energy homeostasis and brown adipose tissue phenotype in high-fat diet-induced obese mice.Sachs, S. ; Götz, A. ; Finan, B. ; Feuchtinger, A. ; DiMarchi, R.D. ; Döring, Y. ; Weber, C. ; Tschöp, M.H. ; Müller, T.D. ; Hofmann, S.M.
Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.Contreras, R. ; Gruber, T. ; Gonzales García, I. ; Schriever, S.C. ; de Angelis, M. ; Mallet, N. ; Bernecker, M. ; Legutko, B. ; Kabra, D.G. ; Schmidt, M. ; Tschöp, M.H. ; Gutierrez-Aguilar, R. ; Mellor, J. ; García-Cáceres, C. ; Pfluger, P.T.
HDAC5 controls a hypothalamic STAT5b-TH axis, the sympathetic activation of ATP-consuming futile cycles and adult-onset obesity in male mice.Lebas, M. ; Chinigò, G. ; Courmont, E. ; Bettaieb, L. ; Machmouchi, A. ; Goveia, J. ; Beatovic, A. ; Van Kerckhove, J. ; Robil, C. ; Angulo, F.S. ; Vedelago, M. ; Errerd, A. ; Treps, L. ; Gao, V. ; Delgado De La Herran, H.C. ; Mayeuf-Louchart, A. ; L'homme, L. ; Chamlali, M. ; Dejos, C. ; Gouyer, V. ; Garikipati, V.N.S. ; Tomar, D. ; Yin, H. ; Fukui, H. ; Vinckier, S. ; Stolte, A. ; Conradi, L.C. ; Infanti, F. ; Lemonnier, L. ; Zeisberg, E.M. ; Luo, Y. ; Lin, L. ; Desseyn, J.L. ; Pickering, J.W. ; Kishore, R. ; Madesh, M. ; Dombrowicz, D. ; Perocchi, F. ; Staels, B. ; Pla, A.F. ; Gkika, D. ; Cantelmo, A.R.
Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition.Goll, N. ; Moszka, N. ; Kantartzis, K. ; Preissl, H. ; Gruber, T. ; Fritsche, L. ; Jumpertz von Schwartzenberg, R. ; García-Cáceres, C. ; Fritsche, A. ; Hallschmid, M.
Oxytocin does not acutely improve glucose tolerance in men with type 2 diabetes.Decoster, L. ; Trova, S. ; Zucca, S. ; Bulk, J. ; Gouveia, A. ; Ternier, G. ; Lhomme, T. ; Legrand, A. ; Gallet, S. ; Boehm, U. ; Wyatt, A. ; Wahl, V. ; Wartenberg, P. ; Hrabovszky, E. ; Rácz, G. ; Luzzati, F. ; Nato, G. ; Fogli, M. ; Peretto, P. ; Schriever, S.C. ; Bernecker, M. ; Pfluger, P.T. ; Steculorum, S.M. ; Bovetti, S. ; Rasika, S. ; Prévot, V. ; Silva, M.S.B. ; Giacobini, P.
A GnRH neuronal population in the olfactory bulb translates socially relevant odors into reproductive behavior in male mice.Forst, T. ; de Block, C. ; Del Prato, S. ; Armani, S. ; Frias, J. ; Lautenbach, A. ; Ludvik, B. ; Marinez, M. ; Mathieu, C. ; Müller, T.D. ; Schnell, O.
The role of incretin receptor agonists in the treatment of obesity.Krause, C. ; Britsemmer, J.H. ; Bernecker, M. ; Molenaar, A. ; Taege, N. ; Lopez-Alcantara, N. ; Geißler, C. ; Kaehler, M. ; Iben, K. ; Judycka, A. ; Wagner, J. ; Wolter, S. ; Mann, O. ; Pfluger, P.T. ; Cascorbi, I. ; Lehnert, H. ; Stemmer, K. ; Schriever, S.C. ; Kirchner, H.
Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity.Chen, B. ; de Launoit, E. ; Meseguer, D. ; García-Cáceres, C. ; Eichmann, A. ; Renier, N. ; Schneeberger, M.
The interactions between energy homeostasis and neurovascular plasticity.Kusminski, C.M. ; Perez-Tilve, D. ; Müller, T.D. ; DiMarchi, R.D. ; Tschöp, M.H. ; Scherer, P.E.
Transforming obesity: The advancement of multi-receptor drugs.Brunner, S. ; Höring, M. ; Liebisch, G. ; Schweizer, S. ; Scheiber, J. ; Giansanti, P. ; Hidrobo, M.S. ; Hermeling, S. ; Oeckl, J. ; Prudente de Mello, N. ; Perocchi, F. ; Seeliger, C. ; Strohmeyer, A. ; Klingenspor, M. ; Plagge, J. ; Küster, B. ; Burkhardt, R. ; Janssen, K.P. ; Ecker, J.
Mitochondrial lipidomes are tissue specific - low cholesterol contents relate to UCP1 activity.Wunderlich, M. ; Miller, M. ; Ritter, B. ; Le Gleut, R. ; Marchi, H. ; Majzoub-Altweck, M. ; Knerr, P.J. ; Douros, J.D. ; Müller, T.D. ; Brielmeier, M.
Experimental colonization with H. hepaticus, S. aureus and R. pneumotropicus does not influence the metabolic response to high-fat diet or incretin-analogues in wildtype SOPF mice.Novikoff, A. ; Müller, T.D.
Antagonizing GIPR adds fire to the GLP-1R flame.Zhu, Q. ; Chen, S. ; Funcke, J.B. ; Straub, L.G. ; Lin, Q. ; Zhao, S. ; Joung, C. ; Zhang, Z. ; Kim, D.S. ; Li, N. ; Gliniak, C.M. ; Lee, C. ; Cebrian Serrano, A. ; Pedersen, L. ; Halberg, N. ; Gordillo, R. ; Kusminski, C.M. ; Scherer, P.E.
PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels.Singh, T. ; Weiss, A. ; Vehik, K. ; Krischer, J. ; Rewers, M. ; Toppari, J. ; Lernmark, Å. ; Hagopian, W. ; Akolkar, B. ; Bonifacio, E. ; Ziegler, A.-G. ; Winkler, C.
Caesarean section and risk of type 1 diabetes.Le Thuc, O. ; García-Cáceres, C.
Obesity-induced inflammation: Connecting the periphery to the brain.Keipert, S. ; Gaudry, M.J. ; Kutschke, M. ; Keuper, M. ; Dela Rosa, M.A.S. ; Cheng, Y. ; Monroy Kuhn, J.M. ; Laterveer, R. ; Cotrim, C.A. ; Giere, P. ; Perocchi, F. ; Feederle, R. ; Crichton, P.G. ; Lutter, D. ; Jastroch, M.
Two-stage evolution of mammalian adipose tissue thermogenesis.Hönes, G.S. ; Geist, D. ; Wenzek, C. ; Pfluger, P.T. ; Müller, T.D. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Dragano, N.R.V. ; Garrett, L. ; Hölter, S.M. ; Rathkolb, B. ; Rozman, J. ; Spielmann, N. ; Treise, I. ; Wolf, E. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Führer, D. ; Moeller, L.C.
Comparative phenotyping of mice reveals canonical and noncanonical physiological functions of TRα and TRβ.Storck, K. ; Ussar, S. ; Kotz, S. ; Altun, I. ; Hu, F. ; Birk, A. ; Veit, J. ; Kovacevic, M.
Characterization of fat used for the optimization of the soft tissue envelope of the nose in rhinoplasty.Yan, X. ; Ussar, S.
Cellular precision modulation of JAK1: Tailoring therapies for allergic lung inflammation.Gruber, T. ; Lechner, F. ; Krieger, J.P. ; García-Cáceres, C.
Neuroendocrine gut-brain signaling in obesity.Vecellio Reane, D. ; Serna, J.D.C. ; Raffaello, A.
Unravelling the complexity of the mitochondrial Ca2+ uniporter: Regulation, tissue specificity, and physiological implications.Kühnen, P. ; Argente, J. ; Clément, K. ; Dollfus, H. ; Dubern, B. ; Farooqi, S. ; de Groot, C. ; Grüters, A. ; Holm, J.C. ; Hopkins, M. ; Kleinendorst, L. ; Körner, A. ; Meeker, D. ; Rydén, M. ; von Schnurbein, J. ; Tschöp, M.H. ; Yeo, G.S.H. ; Zorn, S. ; Wabitsch, M.
IMPROVE 2022 International Meeting on pathway-related obesity: Vision of excellence.Gutgesell, R.M. ; Nogueiras, R. ; Tschöp, M.H. ; Müller, T.D.
Dual and triple incretin-based co-agonists: Novel therapeutics for obesity and diabetes.Liskiewicz, A. ; Müller, T.D.
Regulation of energy metabolism through central GIPR signaling.Corrêa-da-Silva, F. ; Carter, J. ; Wang, X.Y. ; Sun, R. ; Pathak, E. ; Monroy Kuhn, J.M. ; Schriever, S.C. ; Maya-Monteiro, C.M. ; Jiao, H. ; Kalsbeek, M.J. ; Moraes-Vieira, P.M.M. ; Gille, J.J.P. ; Sinnema, M. ; Stumpel, C.T.R.M. ; Curfs, L.M.G. ; Stenvers, D.J. ; Pfluger, P.T. ; Lutter, D. ; Pereira, A.M. ; Kalsbeek, A. ; Fliers, E. ; Swaab, D.F. ; Wilkinson, L. ; Gao, Y. ; Yi, C.X.
Microglial phagolysosome dysfunction and altered neural communication amplify phenotypic severity in Prader-Willi Syndrome with larger deletion.Klingelhuber, F. ; Frendo-Cumbo, S. ; Omar-Hmeadi, M. ; Massier, L. ; Kakimoto, P. ; Taylor, A.J. ; Couchet, M. ; Ribicic, S. ; Wabitsch, M. ; Messias, A.C. ; Iuso, A. ; Müller, T.D. ; Rydén, M. ; Mejhert, N. ; Krahmer, N.
A spatiotemporal proteomic map of human adipogenesis.Schnell, O. ; Barnard-Kelly, K. ; Battelino, T. ; Ceriello, A. ; Larsson, H.E. ; Fernández-Fernández, B. ; Forst, T. ; Frias, J.P. ; Gavin, J.R. ; Giorgino, F. ; Groop, P.H. ; Heerspink, H.J.L. ; Herzig, S. ; Hummel, M. ; Huntley, G. ; Ibrahim, M. ; Itzhak, B. ; Jacob, S. ; Ji, L. ; Kosiborod, M. ; Lalic, N. ; Macieira, S. ; Malik, R.A. ; Mankovsky, B. ; Marx, N. ; Mathieu, C. ; Müller, T.D. ; Ray, K.K. ; Rodbard, H.W. ; Rossing, P. ; Rydén, L. ; Schumm-Draeger, P.M. ; Schwarz, P. ; Škrha, J. ; Snoek, F. ; Tacke, F. ; Taylor, B. ; Jeppesen, B.T. ; Tesfaye, S. ; Topsever, P. ; Vilsbøll, T. ; Yu, X. ; Standl, E.
CVOT Summit Report 2023: New cardiovascular, kidney, and metabolic outcomes.Müller, G. ; Müller, T.D.
Transfer of membrane(s) matter(s)-non-genetic inheritance of (metabolic) phenotypes?Akindehin, S.E. ; Liskiewicz, A. ; Liskiewicz, D. ; Bernecker, M. ; García-Cáceres, C. ; Drucker, D.J. ; Finan, B. ; Grandl, G. ; Gutgesell, R.M. ; Hofmann, S.M. ; Khalil, A. ; Liu, X. ; Cota, P. ; Bakhti, M. ; Czarnecki, O. ; Bastidas-Ponce, A. ; Lickert, H. ; Kang, L. ; Maity-Kumar, G. ; Novikoff, A. ; Parlee, S. ; Pathak, E. ; Schriever, S.C. ; Sterr, M. ; Ussar, S. ; Zhang, Q. ; DiMarchi, R. ; Tschöp, M.H. ; Pfluger, P.T. ; Douros, J.D. ; Müller, T.D.
Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice.Grandl, G. ; Collden, G. ; Feng, J. ; Bhattacharya, S. ; Klingelhuber, F. ; Schomann, L. ; Bilekova, S. ; Ansarullah ; Xu, W. ; Fathi Far, F. ; Tost, M. ; Gruber, T. ; Bastidas-Ponce, A. ; Zhang, Q. ; Novikoff, A. ; Liskiewicz, A. ; Liskiewicz, D. ; García-Cáceres, C. ; Feuchtinger, A. ; Tschöp, M.H. ; Krahmer, N. ; Lickert, H. ; Müller, T.D.
Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity.Grabowska, K. ; Grabowski, M. ; Przybyła, M. ; Pondel, N. ; Barski, J.J. ; Nowacka-Chmielewska, M. ; Liskiewicz, D.
Ketogenic diet and behavior: Insights from experimental studies.Novikoff, A. ; Müller, T.D.
Pharmacological advances in incretin-based polyagonism - what we know and what we don'tt.Reverte-Salisa, L. ; Siddig, S. ; Hildebrand, S. ; Yao, X. ; Zurkovic, J. ; Jaeckstein, M.Y. ; Heeren, J. ; Lezoualc’h, F. ; Krahmer, N. ; Pfeifer, A.
EPAC1 enhances brown fat growth and beige adipogenesis.Ludzki, A.C. ; Hansen, M. ; Zareifi, D. ; Jalkanen, J. ; Huang, Z. ; Omar-Hmeadi, M. ; Renzi, G. ; Klingelhuber, F. ; Boland, S. ; Ambaw, Y.A. ; Wang, N. ; Damdimopoulos, A.E. ; Liu, J. ; Jernberg, T. ; Petrus, P. ; Arner, P. ; Krahmer, N. ; Fan, R. ; Treuter, E. ; Gao, H. ; Rydén, M. ; Mejhert, N.
Transcriptional determinants of lipid mobilization in human adipocytes.Cota, P. ; Caliskan, Ö.S. ; Bastidas-Ponce, A. ; Jing, C. ; Jaki, J. ; Saber, L. ; Czarnecki, O. ; Taskin, D. ; Blöchinger, A. ; Kurth, T. ; Sterr, M. ; Burtscher, I. ; Krahmer, N. ; Lickert, H. ; Bakhti, M.
Insulin regulates human pancreatic endocrine cell differentiation in vitro.Ntziachristos, V. ; Quake, S.R. ; Tschöp, M.H.
An engineering makeover of biomedical research.Bauer, M.
The Role of Adipocyte-derived Extracellular Vesicles in Metabolic Diseases.D'Angelo, D. ; Vecellio Reane, D. ; Raffaello, A.
Neither too much nor too little: Mitochondrial calcium concentration as a balance between physiological and pathological conditions.Le Thuc, O. ; Gruber, T. ; Tschöp, M.H. ; García-Cáceres, C.
Correction to: Control of Systemic Metabolism by Astrocytes in the Brain (Springer Nature, 10.1007/978-3-030-62383-8_6).Tschöp, M.H. ; Friedman, J.M.
Seeking satiety: From signals to solutions.Couchet, M. ; Gao, H. ; Klingelhuber, F. ; Jalkanen, J. ; De Castro Barbosa, T. ; Omar-Hmeadi, M. ; Massier, L. ; Krahmer, N. ; Mejhert, N. ; Rydén, M.
Adipogenic characterization of immortalized CD55+ progenitor cells from human white adipose tissue.González-Vila, A. ; Luengo-Mateos, M. ; Silveira-Loureiro, M. ; Garrido-Gil, P. ; Ohinska, N. ; González-Domínguez, M. ; Labandeira-García, J.L. ; García-Cáceres, C. ; López, M. ; Barca-Mayo, O.
Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic manner.Liskiewicz, A. ; Khalil, A. ; Liskiewicz, D. ; Novikoff, A. ; Grandl, G. ; Maity-Kumar, G. ; Gutgesell, R.M. ; Bakhti, M. ; Bastidas-Ponce, A. ; Czarnecki, O. ; Makris, K. ; Lickert, H. ; Feuchtinger, A. ; Tost, M. ; Coupland, C. ; Ständer, L. ; Akindehin, S.E. ; Prakash, S. ; Abrar, F. ; Castelino, R.L. ; He, Y. ; Knerr, P.J. ; Yang, B. ; Hogendorf, W.F.J. ; Zhang, S. ; Hofmann, S.M. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Douros, J.D. ; Müller, T.D.
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice.Zhang, W. ; Nowotny, H. ; Theodoropoulou, M. ; Simon, J. ; Hemmer, C.M. ; Bidlingmaier, M. ; Auer, M.K. ; Reincke, M. ; Uhlenhaut, N.H. ; Reisch, N.
E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess.Müller, T.D.
Regulation des Energiestoffwechsel durch GIP und GIPR:GLP-1R Ko-Agonisten.Novikoff, A. ; Müller, T.D.
SURMOUNTing body weight barriers in type 2 diabetes.Stemmer, K. ; Müller, T.D.
GLP-1-Mimetika – wegweisend zur Behandlung von Diabetes und Adipositas.Plaza-Díaz, J. ; Ruiz Ojeda, F.J. ; Gil, A.
Microbiota of the intestine: Biology and physiological functions.Lee, K.Y. ; Emanuelli, B. ; Ussar, S.
Editorial: Healthy adipose tissue expansion.Carrasco Del Amor, A. ; Hernandez-Bautista, R. ; Ussar, S. ; Cristobal, S. ; Urbatzka, R.
Insights into the mechanism of action of the chlorophyll derivative 13-2-hydroxypheophytine a on reducing neutral lipid reserves in zebrafish larvae and mice adipocytes.Gruber, T. ; Contreras, R. ; Sánchez Quant, E.S. ; Miok, V. ; Makris, K. ; Le Thuc, O. ; Gonzales García, I. ; Garcia-Clavé, E. ; Althammer, F. ; Krabichler, Q. ; DeCamp, L.M. ; Jones, R.G. ; Lutter, D. ; Williams, R.H. ; Pfluger, P.T. ; Müller, T.D. ; Woods, S.C. ; Pospisilik, J.A. ; Martinez-Jimenez, C.P. ; Tschöp, M.H. ; Grinevich, V. ; García-Cáceres, C.
High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling.Meindl, K. ; Issler, N. ; Afonso, S. ; Cebrian Serrano, A. ; Müller, K. ; Sterner, C. ; Othmen, H. ; Tegtmeier, I. ; Witzgall, R. ; Klootwijk, E. ; Davies, B. ; Kleta, R. ; Warth, R.
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility.Ribeiro, T. ; Jónsdóttir, K. ; Hernandez-Bautista, R. ; Silva, N.G. ; Sánchez-Astráin, B. ; Samadi, A. ; Eiriksson, F.F. ; Thorsteinsdóttir, M. ; Ussar, S. ; Urbatzka, R.
Metabolite profile characterization of cyanobacterial strains with bioactivity on lipid metabolism using in vivo and in vitro approaches.González-García, I. ; García-Cáceres, C.
Astrocytic GABA in LHA is an obesity ‘thermostat’.Alkhoury, C. ; Henneman, N.F. ; Petrenko, V. ; Shibayama, Y. ; Segaloni, A. ; Gadault, A. ; Nemazanyy, I. ; Le Guillou, E. ; Wolide, A.D. ; Antoniadou, K. ; Tong, X. ; Tamaru, T. ; Ozawa, T. ; Girard, M. ; Hnia, K. ; Lutter, D. ; Dibner, C. ; Panasyuk, G.
Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis.Liu, X. ; Khalil, A. ; Muthukumarasamy, U. ; Onogi, Y. ; Yan, X. ; Singh, I. ; Lopez Gonzales, E. ; Israel, A. ; Cebrian Serrano, A. ; Strowig, T. ; Ussar, S.
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice.Müller, G. ; Müller, T.D.
(Patho)physiology of glycosylphosphatidylinositol-anchored proteins II: Intercellular transfer of matter (Inheritance?) that matters.Jacob, C. ; Olliges, E. ; Haile, A. ; Hoffmann, V. ; Jacobi, B. ; Steinkopf, L. ; Lanz, M. ; Wittmann, M. ; Tschöp, M.H. ; Meissner, K.
Placebo effects on nausea and motion sickness are resistant to experimentally-induced stress.Prudente de Mello, N. ; Fecher, C. ; Pastor, A.M. ; Perocchi, F. ; Misgeld, T.
Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice.Rosowski, S. ; Remmert, C. ; Marder, M. ; Akishiba, M. ; Bushe, J. ; Feuchtinger, A. ; Platen, A. ; Ussar, S. ; Theis, F.J. ; Wiedenmann, S. ; Meier, M.
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment.Wewer Albrechtsen, N.J. ; Holst, J.J. ; Cherrington, A.D. ; Finan, B. ; Gluud, L.L. ; Dean, E.D. ; Campbell, J.E. ; Bloom, S.R. ; Tan, T.M.M. ; Knop, F.K. ; Müller, T.D.
100 years of glucagon and 100 more.Bustos-Aibar, M. ; Aguilera, C.M. ; Alcalá-Fdez, J. ; Ruiz Ojeda, F.J. ; Plaza-Díaz, J. ; Plaza-Florido, A. ; Tofe, I. ; Gil-Campos, M. ; Gacto, M.J. ; Anguita-Ruiz, A.
Shared gene expression signatures between visceral adipose and skeletal muscle tissues are associated with cardiometabolic traits in children with obesity.Giroud, M. ; Kotschi, S. ; Kwon, Y. ; Le Thuc, O. ; Hoffmann, A. ; Gil Lozano, M. ; Karbiener, M. ; Higareda-Almaraz, J. ; Khani, S. ; Tews, D. ; Fischer-Posovszky, P. ; Sun, W. ; Dong, H. ; Ghosh, A. ; Wolfrum, C. ; Wabitsch, M. ; Virtanen, K.A. ; Blüher, M. ; Nielsen, S. ; Zeigerer, A. ; García-Cáceres, C. ; Scheideler, M. ; Herzig, S. ; Bartelt, A.
The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes.Bilekova, S. ; Garcia-Colomer, B. ; Cebrian Serrano, A. ; Schirge, S. ; Krey, K. ; Sterr, M. ; Kurth, T. ; Hauck, S.M. ; Lickert, H.
Inceptor facilitates acrosomal vesicle formation in spermatids and is required for male fertility.Becker, M. ; Joseph, S.S. ; Garcia-Carrizo, F. ; Tom, R.Z. ; Opaleva, D. ; Serr, I. ; Tschöp, M.H. ; Schulz, T. ; Hofmann, S.M. ; Daniel, C.
Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration.Lugar, M. ; Eugster, A. ; Achenbach, P. ; von dem Berge, T. ; Berner, R. ; Besser, R.E.J. ; Casteels, K. ; Elding Larsson, H. ; Gemulla, G. ; Kordonouri, O. ; Lindner, A. ; Lundgren, M. ; Müller, D. ; Oltarzewski, M. ; Rochtus, A. ; Scholz, M. ; Szypowska, A. ; Todd, J.A. ; Ziegler, A.-G. ; Bonifacio, E.
SARS-CoV-2 infection and development of islet autoimmunity in early childhood.Wagner, L. ; Veit, R. ; Kübler, C. ; Fritsche, A. ; Häring, H.-U. ; Birkenfeld, A.L. ; Heni, M. ; Preissl, H. ; Kullmann, S.
Brain insulin responsiveness is linked to age and peripheral insulin sensitivity.Novikoff, A. ; Müller, T.D.
The molecular pharmacology of glucagon agonists in diabetes and obesity.Liskiewicz, D. ; Zhang, Q. ; Barthem, C.S. ; Jastroch, M. ; Liskiewicz, A. ; Khajavi, N. ; Grandl, G. ; Coupland, C. ; Kleinert, M. ; García-Cáceres, C. ; Novikoff, A. ; Maity-Kumar, G. ; Boehm, U. ; Tschöp, M.H. ; Müller, T.D.
Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice.Yu, Q. ; Gamayun, I. ; Wartenberg, P. ; Zhang, Q. ; Qiao, S. ; Kusumakshi, S. ; Candlish, S. ; Götz, V. ; Wen, S. ; Das, D. ; Wyatt, A. ; Wahl, V. ; Ectors, F. ; Kattler, K. ; Yildiz, D. ; Prévot, V. ; Schwaninger, M. ; Ternier, G. ; Giacobini, P. ; Ciofi, P. ; Müller, T.D. ; Boehm, U.
Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis.Zani, F. ; Blagih, J. ; Gruber, T. ; Buck, M.D. ; Jones, N. ; Hennequart, M. ; Newell, C.L. ; Pilley, S.E. ; Soro-Barrio, P. ; Kelly, G. ; Legrave, N.M. ; Cheung, E.C. ; Gilmore, I.S. ; Gould, A.P. ; García-Cáceres, C. ; Vousden, K.H.
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.Müller, G. ; Müller, T.D.
Transfer of proteins from cultured human adipose to blood cells and induction of anabolic phenotype are controlled by serum, insulin and sulfonylurea drugs.Gonzales García, I. ; Garcia-Clavé, E. ; Cebrian Serrano, A. ; Le Thuc, O. ; Contreras, R. ; Xu, Y. ; Gruber, T. ; Schriever, S.C. ; Legutko, B. ; Lintelmann, J. ; Adamski, J. ; Wurst, W. ; Müller, T.D. ; Woods, S.C. ; Pfluger, P.T. ; Tschöp, M.H. ; Fisette, A. ; García-Cáceres, C.
Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1.Jastroch, M. ; Keipert, S. ; Tschöp, M.H.
Protection from alcohol intoxication: Must be FGF21 to enter.Nogueiras, R. ; Nauck, M.A. ; Tschöp, M.H.
Gut hormone co-agonists for the treatment of obesity: From bench to bedside.El, K. ; Douros, J.D. ; Willard, F.S. ; Novikoff, A. ; Sargsyan, A. ; Perez-Tilve, D. ; Wainscott, D.B. ; Yang, B. ; Chen, A. ; Wothe, D. ; Coupland, C. ; Tschöp, M.H. ; Finan, B. ; D'Alessio, D.A. ; Sloop, K.W. ; Müller, T.D. ; Campbell, J.E.
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.Glunk, V. ; Laber, S. ; Sinnott-Armstrong, N. ; Sobreira, D.R. ; Strobel, S.M. ; Batista, T.M. ; Kubitz, P. ; Moud, B.N. ; Ebert, H. ; Huang, Y. ; Brandl, B. ; Garbo, G. ; Honecker, J. ; Stirling, D.R. ; Abdennur, N. ; Calabuig-Navarro, V. ; Skurk, T. ; Ocvirk, S. ; Stemmer, K. ; Cimini, B.A. ; Carpenter, A.E. ; Dankel, S.N. ; Lindgren, C.M. ; Hauner, H ; Nobrega, M.A. ; Claussnitzer, M.
A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes.Müller, G. ; Müller, T.D.
(Patho)Physiology of glycosylphosphatidylinositol-anchored proteins I: localization at plasma membranes and extracellular compartments.Tsesmelis, K. ; Maity-Kumar, G. ; Croner, D. ; Sprissler, J. ; Tsesmelis, M. ; Hein, T. ; Baumann, B. ; Wirth, T.
Accelerated aging in mice with astrocytic redox imbalance as a consequence of SOD2 deletion.Campbell, J.E. ; Müller, T.D. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; D'Alessio, D.A.
GIPR/GLP-1R dual agonist therapies for diabetes and weight loss-chemistry, physiology, and clinical applications.Cuyutupa, V.R. ; Moser, D. ; Diedrich, V. ; Cheng, Y. ; Billaud, J.N. ; Haugg, E. ; Singer, D. ; Bereiter-Hahn, J. ; Herwig, A. ; Choukér, A.
Blood transcriptomics mirror regulatory mechanisms during hibernation-a comparative analysis of the Djungarian hamster with other mammalian species.Capelo-Diz, A. ; Lachiondo-Ortega, S. ; Fernández-Ramos, D. ; Cañas-Martín, J. ; Goikoetxea-Usandizaga, N. ; Serrano-Maciá, M. ; Gonzalez-Rellan, M.J. ; Mosca, L. ; Blazquez-Vicens, J. ; Tinahones-Ruano, A. ; Fondevila, M.F. ; Buyan, M. ; Delgado, T.C. ; Gutierrez de Juan, V. ; Ayuso-García, P. ; Sánchez-Rueda, A. ; Velasco-Avilés, S. ; Fernández-Susavila, H. ; Riobello-Suárez, C. ; Dziechciarz, B. ; Montiel-Duarte, C. ; Lopitz-Otsoa, F. ; Bizkarguenaga, M. ; Bilbao-García, J. ; Bernardo-Seisdedos, G. ; Senra, A. ; Soriano-Navarro, M. ; Millet, O. ; Díaz-Lagares, ; Crujeiras, A.B. ; Bao-Caamano, A. ; Cabrera, D. ; van Liempd, S. ; Tamayo-Carro, M. ; Borzacchiello, L. ; Gomez-Santos, B. ; Buqué, X. ; Sáenz de Urturi, D. ; González-Romero, F. ; Simon, J. ; Rodríguez-Agudo, R. ; Ruiz, A. ; Matute, C. ; Beiroa, D. ; Falcón-Pérez, J.M. ; Aspichueta, P. ; Rodríguez-Cuesta, J. ; Porcelli, M. ; Pajares, M.A. ; Ameneiro, C. ; Fidalgo, M. ; Aransay, A.M. ; Lama-Díaz, T. ; Blanco, M.G. ; López, M. ; Villa-Bellosta, R. ; Müller, T.D. ; Nogueiras, R. ; Woodhoo, A. ; Martínez-Chantar, M.L. ; Varela-Rey, M.
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting.Tai, Y.H. ; Engels, D. ; Locatelli, G. ; Emmanouilidis, I. ; Fecher, C. ; Theodorou, D. ; Müller, S.A. ; Licht-Mayer, S. ; Kreutzfeldt, M. ; Wagner, I. ; Prudente de Mello, N. ; Gkotzamani, S.N. ; Trovò, L. ; Kendirli, A. ; Aljović, A. ; Breckwoldt, M.O. ; Naumann, R. ; Bareyre, F.M. ; Perocchi, F. ; Mahad, D. ; Merkler, D. ; Lichtenthaler, S.F. ; Kerschensteiner, M. ; Misgeld, T.
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions.Müller, T.D. ; Blüher, M.
Adipositastherapie – werden Pharmakotherapien die Alternative zur metabolischen Chirurgie sein?Kolabas, Z.I. ; Kuemmerle, L. ; Perneczky, R. ; Förstera, B. ; Ulukaya, S. ; Ali, M. ; Kapoor, S. ; Bartos, L.M. ; Büttner, M. ; Caliskan, Ö.S. ; Rong, Z. ; Mai, H. ; Höher, L. ; Jeridi, D. ; Molbay, M. ; Khalin, I. ; Deligiannis, I.K. ; Negwer, M. ; Roberts, K. ; Simats, A. ; Carofiglio, O. ; Todorov, M.I. ; Horvath, I. ; Öztürk, F. ; Hummel, S. ; Biechele, G. ; Zatcepin, A. ; Unterrainer, M. ; Gnörich, J. ; Roodselaar, J. ; Shrouder, J. ; Khosravani, P. ; Tast, B. ; Richter, L. ; Díaz-Marugán, L. ; Kaltenecker, D. ; Lux, L. ; Chen, Y. ; Zhao, S. ; Rauchmann, B.S. ; Sterr, M. ; Kunze, I. ; Stanic Aguilera, K.N. ; Kan, V.W.Y. ; Besson-Girard, S. ; Katzdobler, S. ; Palleis, C. ; Schädler, J. ; Paetzold, J.C. ; Liebscher, S. ; Hauser, A.E. ; Gokce, O. ; Lickert, H. ; Steinke, H. ; Benakis, C. ; Braun, C. ; Martinez Jimenez, C.P. ; Buerger, K. ; Albert, N.L. ; Höglinger, G. ; Levin, J. ; Haass, C. ; Kopczak, A. ; Dichgans, M. ; Havla, J. ; Kümpfel, T. ; Kerschensteiner, M. ; Schifferer, M. ; Simons, M. ; Liesz, A. ; Krahmer, N. ; Bayraktar, O.A. ; Franzmeier, N. ; Plesnila, N. ; Erener, S. ; Puelles, V.G. ; Delbridge, C. ; Bhatia, H.S. ; Hellal, F. ; Elsner, M. ; Bechmann, I. ; Ondruschka, B. ; Brendel, M. ; Theis, F.J. ; Ertürk, A.
Distinct molecular profiles of skull bone marrow in health and neurological disorders.Plaza-Díaz, J. ; Ruiz Ojeda, F.J. ; Morales, J. ; Martín-Masot, R. ; Climent, E. ; Silva, ; Martinez-Blanch, J.F. ; Enrique, M. ; Tortajada, M. ; Ramon, D. ; Alvarez, B. ; Chenoll, E. ; Gil, Á.
Innova 2020: A follow-up study of the fecal microbiota of infants using a novel infant formula between 6 months and 12 months of age.Rajcsanyi, L.S. ; Hoffmann, A. ; Ghosh, A. ; Matrisch-Dinkler, B. ; Zheng, Y. ; Peters, T. ; Sun, W. ; Dong, H. ; Noé, F. ; Wolfrum, C. ; Herpertz-Dahlmann, B. ; Seitz, J. ; de Zwaan, M. ; Herzog, W. ; Ehrlich, S. ; Zipfel, S. ; Giel, K. ; Egberts, K. ; Burghardt, R. ; Föcker, M. ; Tsai, L.T. ; Müller, T.D. ; Blüher, M. ; Hebebrand, J. ; Hirtz, R. ; Hinney, A.
Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa.Tschöp, M.H. ; Nogueiras, R. ; Ahrén, B.
Gut hormone-based pharmacology: Novel formulations and future possibilities for metabolic disease therapy.Daniels, M. ; Fischer-Posovszky, P. ; Boschmann, M. ; Jumpertz von Schwartzenberg, R. ; Müller, T.D. ; Sandforth, L. ; Frank-Podlech, S. ; Hülskämper, S. ; Peter, A. ; Wabitsch, M. ; Jordan, J. ; Birkenfeld, A.L.
Atrial natriuretic peptide and leptin interactions in healthy men.Sachs, S. ; Götz, A. ; Finan, B. ; Feuchtinger, A. ; DiMarchi, R.D. ; Döring, Y. ; Weber, C. ; Tschöp, M.H. ; Müller, T.D. ; Hofmann, S.M.
GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.Ruiz Ojeda, F.J. ; Anguita-Ruiz, A. ; Rico, M.C. ; Leis, R. ; Bueno, G. ; Moreno, L.A. ; Gil-Campos, M. ; Gil, Á. ; Aguilera, C.M.
Serum levels of the novel adipokine isthmin-1 are associated with obesity in pubertal boys.Rial-Pensado, E. ; Canaple, L. ; Guyot, R. ; Clemmensen, C. ; Wiersema, J. ; Wu, S. ; Richard, S. ; Boelen, A. ; Müller, T.D. ; López, M. ; Flamant, F. ; Gauthier, K.
Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice.Lutter, D. ; Sachs, S. ; Walter, M.C. ; Kerege, A. ; Perreault, L. ; Kahn, D.E. ; Wolide, A.D. ; Kleinert, M. ; Bergman, B.C. ; Hofmann, S.M.
Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response.Begemann, K. ; Heyde, I. ; Witt, P. ; Inderhees, J. ; Leinweber, B. ; Koch, C.E. ; Jöhren, O. ; Oelkrug, R. ; Liskiewicz, A. ; Müller, T.D. ; Oster, H.
Rest phase snacking increases energy resorption and weight gain in male mice.Montalban, E. ; Walle, R. ; Castel, J. ; Ansoult, A. ; Hassouna, R. ; Foppen, E. ; Fang, X. ; Hutelin, Z. ; Mickus, S. ; Perszyk, E. ; Petitbon, A. ; Berthelet, J. ; Rodrigues-Lima, F. ; Cebrian Serrano, A. ; Gangarossa, G. ; Martin, C. ; Trifilieff, P. ; Bosch-Bouju, C. ; Small, D. ; Luquet, S.
The addiction-susceptibility TaqIA/Ankyrin repeat and kinase domain containing 1 kinase (ANKK1) controls reward and metabolism through dopamine receptor type 2 (D2R)-expressing neurons.Ruiz Ojeda, F.J. ; Plaza-Díaz, J. ; Morales, J. ; Álvarez-Calatayud, G. ; Climent, E. ; Silva, A. ; Martinez-Blanch, J.F. ; Enrique, M. ; Tortajada, M. ; Ramon, D. ; Alvarez, B. ; Chenoll, E. ; Gil, A.
Effects of a novel infant formula on the fecal microbiota in the first six months of life: The INNOVA 2020 Study.Kulaj, K. ; Harger, A. ; Bauer, M. ; Caliskan, Ö.S. ; Gupta, T.K. ; Chiang, D.M. ; Milbank, E. ; Reber, J. ; Karlas, A. ; Kotzbeck, P. ; Sailer, D.N. ; Volta, F. ; Lutter, D. ; Prakash, S. ; Merl-Pham, J. ; Ntziachristos, V. ; Hauner, H. ; Pfaffl, M.W. ; Tschöp, M.H. ; Müller, T.D. ; Hauck, S.M. ; Engel, B.D. ; Gerdes, J.M. ; Pfluger, P.T. ; Krahmer, N. ; Stemmer, K.
Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo.Bass, J. ; Tschöp, M.H. ; Beutler, L.R.
Dual gut hormone receptor agonists for diabetes and obesity.Plaza-Díaz, J. ; Ruiz Ojeda, F.J. ; Morales, J. ; de la Torre, A.I.C. ; García-García, A. ; de Prado, C.N. ; Coronel-Rodríguez, C. ; Crespo, C.J. ; Ortega, E. ; Martín-Pérez, E. ; Ferreira, F. ; García-Ron, G. ; Galicia, I. ; Santos-García-Cuéllar, M.T. ; Maroto, M. ; Ruiz, P. ; Martín-Molina, R. ; Viver-Gómez, S. ; Gil, A.
Effects of a novel infant formula on weight gain, body composition, safety and tolerability to infants: The INNOVA 2020 Study.Yan, X. ; Miok, V. ; Karlina, R. ; Böttcher, A. ; Lutter, D. ; Lickert, H. ; Garcia-Caceres, C. ; Ussar, S.
ScRNAseq based analysis of the stromal immune cell composition in murine pre-weaning and adult white adipose tissues .Khajavi, N. ; Beck, A. ; Ricku, K. ; Beyerle, P. ; Jacob, K. ; Syamsul, S.F. ; Belkacemi, A. ; Reinach, P.S. ; Schreier, P.C. ; Salah, H. ; Popp, T. ; Novikoff, A. ; Breit, A. ; Chubanov, V. ; Müller, T.D. ; Zierler, S. ; Gudermann, T.
TRPM7 kinase is required for insulin production and compensatory islet responses during obesity.Moreno-Nombela, S. ; Romero-Parra, J. ; Ruiz Ojeda, F.J. ; Solis-Urra, P. ; Baig, A.T. ; Plaza-Díaz, J.
Genome editing and protein energy malnutrition.Monroy Kuhn, J.M. ; Miok, V. ; Lutter, D.
Correlation-guided Network Integration (CoNI), an R package for integrating numerical omics data that allows multiform graph representations to study molecular interaction networks.Fernandez, A.M. ; Martinez-Rachadell, L. ; Navarrete, M. ; Pose-Utrilla, J. ; Davila, J.C. ; Pignatelli, J. ; Diaz-Pacheco, S. ; Guerra-Cantera, S. ; Viedma-Moreno, E. ; Palenzuela, R. ; Ruiz de Martin Esteban, S. ; Mostany, R. ; García-Cáceres, C. ; Tschöp, M.H. ; Iglesias, T. ; de Ceballos, M.L. ; Gutierrez, A. ; Torres Aleman, I.
Insulin regulates neurovascular coupling through astrocytes.Plaza-Díaz, J. ; Manzano, M. ; Ruiz Ojeda, F.J. ; Giron, M.D. ; Salto, R. ; López-Pedrosa, J.M. ; Santos-Fandila, A. ; Garcia-Corcoles, M.T. ; Rueda, R. ; Gil, A.
Intake of slow-digesting carbohydrates is related to changes in the microbiome and its functional pathways in growing rats with obesity induced by diet.Massacci, G. ; Venafra, V. ; Latini, S. ; Bica, V. ; Pugliese, G.M. ; Graziosi, S. ; Klingelhuber, F. ; Krahmer, N. ; Fischer, T. ; Mougiakakos, D. ; Boettcher, M. ; Perfetto, L. ; Sacco, F.
A key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients.Metzner, K.J. ; Darawsha, O. ; Wang, M. ; Gaur, N. ; Cheng, Y. ; Rödiger, A. ; Frahm, C. ; Witte, O.W. ; Perocchi, F. ; Axer, H. ; Grosskreutz, J. ; Brill, M.S.
Age-dependent increase of cytoskeletal components in sensory axons in human skin.Müller, T.D. ; Tschöp, M.H.
Gut-hormone triple agonists: Clinical safety and metabolic benefits.Musiol, S. ; Harris, C. ; Karlina, R. ; Gostner, J.M. ; Rathkolb, B. ; Schnautz, B. ; Schneider, E. ; Mair, L. ; Vergara, E.E. ; Flexeder, C. ; Koletzko, S. ; Bauer, C.P. ; Schikowski, T. ; Berdel, D. ; von Berg, A. ; Herberth, G. ; Rozman, J. ; Hrabě de Angelis, M. ; Standl, M. ; Schmidt-Weber, C.B. ; Ussar, S. ; Alessandrini, F.
Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice.de Angelis, M. ; Maity-Kumar, G. ; Schriever, S.C. ; Kozlova, E.V. ; Müller, T.D. ; Pfluger, P.T. ; Curras-Collazo, M.C. ; Schramm, K.-W.
Development and validation of an LC-MS/MS methodology for the quantification of thyroid hormones in dko MCT8/OATP1C1 mouse brain.Petrus, P. ; Cervantes, M. ; Samad, M. ; Sato, T. ; Chao, A. ; Sato, S. ; Koronowski, K.B. ; Park, G. ; Alam, Y. ; Mejhert, N. ; Seldin, M.M. ; Monroy Kuhn, J.M. ; Dyar, K.A. ; Lutter, D. ; Baldi, P. ; Kaiser, P. ; Jang, C. ; Sassone-Corsi, P.
Tryptophan metabolism is a physiological integrator regulating circadian rhythms.Niemann, B. ; Haufs-Brusberg, S. ; Puetz, L. ; Feickert, M. ; Jaeckstein, M.Y. ; Hoffmann, A. ; Zurkovic, J. ; Heine, M. ; Trautmann, E.-M. ; Müller, C.E. ; Tönjes, A. ; Schlein, C. ; Jafari, A. ; Eltzschig, H.K. ; Gnad, T. ; Blüher, M. ; Krahmer, N. ; Kovacs, P. ; Heeren, J. ; Pfeifer, A.
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.Lutomska, L.M. ; Miok, V. ; Krahmer, N. ; Gonzales García, I. ; Gruber, T. ; Le Thuc, O. ; Murat, C. ; Legutko, B. ; Sterr, M. ; Saher, G. ; Lickert, H. ; Müller, T.D. ; Ussar, S. ; Tschöp, M.H. ; Lutter, D. ; García-Cáceres, C.
Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner.Maity-Kumar, G. ; Ständer, L. ; de Angelis, M. ; Lee, S. ; Molenaar, A. ; Becker, L. ; Garrett, L. ; Amarie, O.V. ; Hölter, S.M. ; Wurst, W. ; Fuchs, H. ; Feuchtinger, A. ; Gailus-Durner, V. ; García-Cáceres, C. ; Othman, A.E. ; Brockmann, C. ; Schöffling, V.I. ; Beiser, K. ; Krude, H. ; Mroz, P.A. ; Hofmann, S.M. ; Tuckermann, J. ; DiMarchi, R.D. ; Hrabě de Angelis, M. ; Tschöp, M.H. ; Pfluger, P.T. ; Müller, T.D.
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.Haile, A. ; Watts, M. ; Aichner, S. ; Stahlberg, F. ; Hoffmann, V. ; Tschöp, M.H. ; Meissner, K.
Central correlates of placebo effects in nausea differ between men and women.Achenbach, P. ; Hippich, M. ; Zapardiel-Gonzalo, J. ; Karges, B. ; Holl, R.W. ; Petrera, A. ; Bonifacio, E. ; Ziegler, A.-G.
A classification and regression tree analysis identifies subgroups of childhood type 1 diabetes.Sekar, R. ; Motzler, K. ; Kwon, Y. ; Novikoff, A. ; Jülg, J. ; Najafi, B. ; Wang, S. ; Seitz, S. ; Hass, D, ; Gancheva, S. ; Kahl, S. ; Yang, B. ; Finan, B. ; Schwarz, K. ; Okun, J.G. ; Roden, M. ; Blüher, M. ; Müller, T.D. ; Krahmer, N. ; Behrends, C. ; Plettenburg, O. ; Miaczynska, M. ; Herzig, S. ; Zeigerer, A.
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.Quarta, C. ; Stemmer, K. ; Novikoff, A. ; Yang, B. ; Klingelhuber, F. ; Harger, A. ; Bakhti, M. ; Bastidas-Ponce, A. ; Baugé, E. ; Campbell, J.E. ; Capozzi, M.E. ; Clemmensen, C. ; Collden, G. ; Cota, P. ; Douros, J. ; Drucker, D.J. ; Dubois, B. ; Feuchtinger, A. ; García-Cáceres, C. ; Grandl, G. ; Hennuyer, N. ; Herzig, S. ; Hofmann, S.M. ; Knerr, P.J. ; Kulaj, K. ; Lalloyer, F. ; Lickert, H. ; Liskiewicz, A. ; Liskiewicz, D. ; Maity-Kumar, G. ; Perez-Tilve, D. ; Prakash, S. ; Sanchez-Garrido, M.A. ; Zhang, Q. ; Staels, B. ; Krahmer, N. ; DiMarchi, R.D. ; Tschöp, M.H. ; Finan, B. ; Müller, T.D.
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.Herrera Moro Chao, D. ; Kirchner, M.K. ; Pham, C. ; Foppen, E. ; Denis, R.G.P. ; Castel, J. ; Morel, C. ; Montalban, E. ; Hassouna, R. ; Bui, L.C. ; Renault, J. ; Mouffle, C. ; García-Cáceres, C. ; Tschöp, M.H. ; Li, D. ; Martin, C. ; Stern, J.E. ; Luquet, S.H.
Hypothalamic astrocytes control systemic glucose metabolism and energy balance.Galle, E. ; Wong, C.W. ; Ghosh, A. ; Desgeorges, T. ; Melrose, K. ; Hinte, L.C. ; Castellano-Castillo, D. ; Engl, M. ; de Sousa, J.A. ; Ruiz Ojeda, F.J. ; de Bock, K. ; Ruiz, J.R. ; von Meyenn, F.
H3K18 lactylation marks tissue-specific active enhancers.Parikh, S. ; Parikh, R. ; Michael, K. ; Bikovski, L. ; Barnabas, G. ; Mardamshina, M. ; Hemi, R. ; Manich, P. ; Goldstein, N. ; Malcov-Brog, H. ; Ben-Dov, T. ; Glaich, O. ; Liber, D. ; Bornstein, Y. ; Goltseker, K. ; Ben-Bezalel, R. ; Pavlovsky, M. ; Golan, T. ; Spitzer, L. ; Matz, H. ; Gonen, P. ; Percik, R. ; Leibou, L. ; Perluk, T. ; Ast, G. ; Frand, J. ; Brenner, R. ; Ziv, T. ; Khaled, M. ; Ben-Eliyahu, S. ; Barak, S. ; Karnieli-Miller, O. ; Levin, E. ; Gepner, Y. ; Weiss, R. ; Pfluger, P.T. ; Weller, A. ; Levy, C.
Food-seeking behavior is triggered by skin ultraviolet exposure in males.Kullmann, S. ; Goj, T. ; Veit, R. ; Fritsche, L. ; Wagner, L. ; Schneeweiss, P. ; Hoene, M. ; Hoffmann, C. ; Machann, J. ; Niess, A. ; Preissl, H. ; Birkenfeld, A.L. ; Peter, A. ; Häring, H.-U. ; Fritsche, A. ; Moller, A. ; Weigert, C. ; Heni, M.
Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese.Abuhattum, S. ; Kotzbeck, P. ; Schlüßler, R. ; Harger, A. ; Ariza de Schellenberger, A. ; Kim, K. ; Escolano, J.C. ; Müller, T. ; Braun, J. ; Wabitsch, M. ; Tschöp, M.H. ; Sack, I. ; Brankatschk, M. ; Guck, J. ; Stemmer, K. ; Taubenberger, A.V.
Adipose cells and tissues soften with lipid accumulation while in diabetes adipose tissue stiffens.Welman, S. ; Jastroch, M. ; Mzilikazi, N.
Obligatory homeothermy of mesic adapted African striped mice, Rhabdomys pumilio, is governed by seasonal basal metabolism and year-round "thermogenic readiness" of brown adipose tissue.Caliskan, Ö.S. ; Massacci, G. ; Krahmer, N. ; Sacco, F.
Phosphoproteomics and organelle proteomics in pancreatic islets.Artati, A. ; Prehn, C. ; Lutter, D. ; Dyar, K.A.
Untargeted and targeted circadian metabolomics using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and flow injection-electrospray ionization-tandem mass spectrometry (FIA-ESI-MS/MS).Agrawal, S. ; Pathak, E. ; Mishra, R. ; Parveen, A. ; Mishra, S.K. ; Byadgi, P.S. ; Dubey, S.K. ; Chaudhary, A.K. ; Singh, V. ; Chaurasia, R.N. ; Atri, N.
Computational exploration of the dual role of the phytochemical fortunellin: Antiviral activities against SARS-CoV-2 and immunomodulatory abilities against the host.Smith, J.G. ; Sato, T. ; Shimaji, K. ; Koronowski, K.B. ; Petrus, P. ; Cervantes, M. ; Kinouchi, K. ; Lutter, D. ; Dyar, K.A. ; Sassone-Corsi, P.
Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain.Wang, J. ; Onogi, Y. ; Krueger, M. ; Oeckl, J. ; Karlina, R. ; Singh, I. ; Hauck, S.M. ; Feederle, R. ; Li, Y. ; Ussar, S.
PAT2 regulates vATPase assembly and lysosomal acidification in brown adipocytes.Lopez Gonzales, E. ; Lehmann, L. ; Ruiz Ojeda, F.J. ; Hernandez-Bautista, R. ; Altun, I. ; Onogi, Y. ; Khalil, A. ; Liu, X. ; Israel, A. ; Ussar, S.
L-serine supplementation blunts fasting-induced weight regain by increasing brown fat thermogenesis.Sundaram, S.M. ; Pereira, A.A. ; Mueller-Fielitz, H. ; Koepke, H. ; de Angelis, M. ; Müller, T.D. ; Heuer, H. ; Koerbelin, J. ; Krohn, M. ; Mittag, J. ; Nogueiras, R. ; Prévot, V. ; Schwaninger, M.
Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency.Raineri, S. ; Sherriff, J.A. ; Thompson, K.S.J. ; Jones, H. ; Pfluger, P.T. ; Ilott, N.E. ; Mellor, J.
Pharmacologically induced weight loss is associated with distinct gut microbiome changes in obese rats.Altun, I. ; Yan, X. ; Ussar, S.
Immune cell regulation of white adipose progenitor cell fate.Müller, G. ; Müller, T.D.
Biological role of the intercellular transfer of glycosylphosphatidylinositol-anchored proteins: Stimulation of lipid and glycogen synthesis.Tan, Q. ; Akindehin, S.E. ; Orsso, C.E. ; Waldner, R.C. ; DiMarchi, R.D. ; Müller, T.D. ; Haqq, A.M.
Recent advances in incretin-based pharmacotherapies for the treatment of obesity and diabetes.Plaza-Díaz, J. ; Izquierdo, D. ; Torres-Martos, Á. ; Baig, A.T. ; Aguilera, C.M. ; Ruiz Ojeda, F.J.
Impact of physical activity and exercise on the epigenome in skeletal muscle and effects on systemic metabolism.Onogi, Y. ; Ussar, S.
Regulatory networks determining substrate utilization in brown adipocytes.Liu, X. ; Jin, Z. ; Summers, S. ; Derous, D. ; Li, M. ; Li, B. ; Li, L. ; Speakman, J.R.
Calorie restriction and calorie dilution have different impacts on body fat, metabolism, behavior, and hypothalamic gene expression.Kraus, G. ; Weigelt, M. ; Reinhardt, S. ; Petzold, A. ; Dahl, A. ; Bonifacio, E.
Reproducibility of 10x Genomics single cell RNA sequencing method in the immune cell environment.Fritsche, L. ; Hummel, J. ; Wagner, R. ; Löffler, D. ; Hartkopf, J. ; Machann, J. ; Hilberath, J. ; Kantartzis, K. ; Jakubowski, P. ; Pauluschke-Fröhlich, J. ; Brucker, S. ; Hörber, S. ; Häring, H.-U. ; Roden, M. ; Schürmann, A. ; Solimena, M. ; Hrabě de Angelis, M. ; Peter, A. ; Birkenfeld, A.L. ; Preissl, H. ; Fritsche, A. ; Heni, M.
The German Gestational Diabetes Study (PREG), a prospective multicentre cohort study: Rationale, methodology and design.Gruber, T. ; García-Cáceres, C.
Astroglial clean-up of satiety synapses.Giehrl-Schwab, J. ; Giesert, F. ; Rauser, B. ; Lao, C.L. ; Hembach, S. ; Lefort, S. ; Ibarra Del Rio, I.A. ; Koupourtidou, C. ; Luecken, M. ; Truong, D.J.J. ; Fischer-Sternjak, J. ; Masserdotti, G. ; Prakash, N. ; Ninkovic, J. ; Hölter, S.M. ; Vogt Weisenhorn, D.M. ; Theis, F.J. ; Götz, M. ; Wurst, W.
Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.Harbauer, A.B. ; Hees, J.T. ; Wanderoy, S. ; Segura, I. ; Gibbs, W. ; Cheng, Y. ; Ordonez, M. ; Cai, Z. ; Cartoni, R. ; Ashrafi, G. ; Wang, C. ; Perocchi, F. ; He, Z. ; Schwarz, T.L.
Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy.Gonzales García, I. ; Urisarri, A. ; Nogueiras, R. ; Dieguez, C. ; Couce, M.L. ; López, M.
An updated view on human neonatal thermogenesis.Karlina, R. ; Flexeder, C. ; Musiol, S. ; Bhattacharyya, M. ; Schneider, E. ; Altun, I. ; Gschwendtner, S. ; Neumann, A.U. ; Nano, J. ; Schloter, M. ; Peters, A. ; Schulz, H. ; Schmidt-Weber, C.B. ; Standl, M. ; Traidl-Hoffmann, C. ; Alessandrini, F. ; Ussar, S.
Differential effects of lung inflammation on insulin resistance in humans and mice.Sato, S. ; Dyar, K.A. ; Treebak, J.T. ; Jepsen, S.L. ; Ehrlich, A.M. ; Ashcroft, S.P. ; Trost, K. ; Kunzke, T. ; Prade, V.M. ; Small, L. ; Basse, A.L. ; Schönke, M. ; Chen, S. ; Samad, M. ; Baldi, P. ; Barrès, R. ; Walch, A.K. ; Moritz, T. ; Holst, J.J. ; Lutter, D. ; Zierath, J.R. ; Sassone-Corsi, P.
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.Evers, S.S. ; Shao, Y. ; Ramakrishnan, S.K. ; Shin, J.H. ; Bozadjieva-Kramer, N. ; Irmler, M. ; Stemmer, K. ; Sandoval, D.A. ; Shah, Y.M. ; Seeley, R.J.
Gut HIF2α signaling is increased after VSG, and gut activation of HIF2α decreases weight, improves glucose, and increases GLP-1 secretion.Mejhert, N. ; Gabriel, K.R. ; Frendo-Cumbo, S. ; Krahmer, N. ; Song, J. ; Kuruvilla, L. ; Chitraju, C. ; Boland, S. ; Jang, D.K. ; von Grotthuss, M. ; Costanzo, M.C. ; Rydén, M. ; Olzmann, J.A. ; Flannick, J. ; Burtt, N.P. ; Farese, R.V.
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.Müller, T.D. ; Blüher, M. ; Tschöp, M.H. ; DiMarchi, R.D.
Anti-obesity drug discovery: Advances and challenges.Ruiz Ojeda, F.J. ; Plaza-Díaz, J. ; Anguita-Ruiz, A. ; Méndez-Gutiérrez, A. ; Aguilera, C.M.
Adipose Extracellular Matrix Remodeling in Obesity and Insulin Resistance.Gruber, T. ; Woods, S.C. ; Tschöp, M.H. ; García-Cáceres, C.
The Neuroanatomical Organization of Hypothalamic Feeding Circuits.Le Thuc, O. ; Gruber, T. ; Tschöp, M.H. ; García-Cáceres, C.
Control of Systemic Metabolism by Astrocytes in the Brain.Casuso, R.A. ; Al Fazazi, S. ; Plaza-Díaz, J. ; Ruiz Ojeda, F.J. ; Rueda-Robles, A. ; Aragón-Vela, J. ; Huertas, J.R.
Physiological doses of hydroxytyrosol modulate gene expression in skeletal muscle of exercised rats.Tarquis Medina, M. ; Scheibner, K. ; Gonzales García, I. ; Bastidas-Ponce, A. ; Sterr, M. ; Jaki, J. ; Schirge, S. ; García-Cáceres, C. ; Lickert, H. ; Bakhti, M.
Synaptotagmin-13 is a neuroendocrine marker in brain, intestine and pancreas.Verbrugge, S. ; Alhusen, J.A. ; Kempin, S. ; Pillon, N.J. ; Rozman, J. ; Wackerhage, H. ; Kleinert, M.
Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise.Müller, G. ; Tschöp, M.H. ; Müller, T.D.
Chip-based sensing of the intercellular transfer of cell surface proteins: Regulation by the metabolic state.Weiner, J. ; Roth, L.C. ; Kranz, M. ; Brust, P. ; Boelen, A. ; Klöting, N. ; Heiker, J.T. ; Blüher, M. ; Tönjes, A. ; Pfluger, P.T. ; Stumvoll, M. ; Mittag, J. ; Krause, K.
Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels.Aragón-Vela, J. ; Solis-Urra, P. ; Ruiz Ojeda, F.J. ; Álvarez-Mercado, A.I. ; Olivares-Arancibia, J. ; Plaza-Díaz, J.
Impact of exercise on gut microbiota in obesity.Milbank, E. ; Dragano, N.R.V. ; Gonzales García, I. ; Garcia, M.R. ; Rivas-Limeres, V. ; Perdomo, L. ; Hilairet, G. ; Ruiz-Pino, F. ; Mallegol, P. ; Morgan, D.A. ; Iglesias-Rey, R. ; Contreras, C. ; Vergori, L. ; Cuñarro, J. ; Porteiro, B. ; Gavaldà-Navarro, A. ; Oelkrug, R. ; Vidal, A. ; Roa, J. ; Sobrino, T. ; Villarroya, F. ; Diéguez, C. ; Nogueiras, R. ; García-Cáceres, C. ; Tena-Sempere, M. ; Mittag, J. ; Carmen Martínez, M. ; Rahmouni, K. ; Andriantsitohaina, R. ; López, M.
Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation.Holthaus, L. ; Sharma, V. ; Brandt, D. ; Ziegler, A.-G. ; Jastroch, M. ; Bonifacio, E.
Functional and metabolic fitness of human CD4+ T lymphocytes during metabolic stress.Müller, T.D. ; Klingenspor, M. ; Tschöp, M.H.
Publisher Correction: Revisiting energy expenditure: How to correct mouse metabolic rate for body mass.De Bernardis Murat, C. ; García-Cáceres, C.
Astrocyte gliotransmission in the regulation of systemic metabolism.Nagler, J. ; Schriever, S.C. ; Romanov, A. ; Weisenhorn, D.M. ; Wurst, W. ; Pfluger, P.T. ; Schramm, K.-W.
Determination of morphine and norlaudanosoline in murine brain regions by dispersive liquid-liquid micro-extraction and liquid chromatograpy-electrochemical detection.Oppenländer, L. ; Palit, S. ; Stemmer, K. ; Greisle, T. ; Sterr, M. ; Salinno, C. ; Bastidas-Ponce, A. ; Feuchtinger, A. ; Böttcher, A. ; Ansarullah ; Theis, F.J. ; Lickert, H.
Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes.Höfig, K.P. ; Reim, A. ; Gallus, C. ; Wong, E.H. ; Behrens, G. ; Conrad, C. ; Xu, M. ; Kifinger, L. ; Ito-Kureha, T. ; Defourny, K.A.Y. ; Geerlof, A. ; Mautner, J.M. ; Hauck, S.M. ; Baumjohann, D. ; Feederle, R. ; Mann, M. ; Wierer, M. ; Glasmacher, E. ; Heissmeyer, V.
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.Greco, C.M. ; Koronowski, K.B. ; Smith, J.G. ; Shi, J. ; Kunderfranco, P. ; Carriero, R. ; Chen, S. ; Samad, M. ; Welz, P.S. ; Zinna, V.M. ; Mortimer, T. ; Chun, S.K. ; Shimaji, K. ; Sato, T. ; Petrus, P. ; Kumar, A. ; Vaca-Dempere, M. ; Deryagian, O. ; Van, C. ; Monroy Kuhn, J.M. ; Lutter, D. ; Seldin, M.M. ; Masri, S. ; Li, W. ; Baldi, P. ; Dyar, K.A. ; Muñoz-Cánoves, P. ; Benitah, S.A. ; Sassone-Corsi, P.
Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms.Aliluev, A. ; Tritschler, S. ; Sterr, M. ; Oppenländer, L. ; Hinterdobler, J. ; Greisle, T. ; Irmler, M. ; Beckers, J. ; Sun, N. ; Walch, A.K. ; Stemmer, K. ; Kindt, A. ; Krumsiek, J. ; Tschöp, M.H. ; Luecken, M. ; Theis, F.J. ; Lickert, H. ; Böttcher, A.
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.Mei, J. ; Böhland, C. ; Geiger, A. ; Baur, I. ; Berner, K. ; Heuer, S. ; Liu, X. ; Mataite, L. ; Melo-Narváez, M.C. ; Özkaya, E. ; Rupp, A. ; Siebenwirth, C. ; Thoma, F. ; Kling, M.F. ; Friedl, A.A.
Development of a model for fibroblast-led collective migration from breast cancer cell spheroids to study radiation effects on invasiveness.Gonzalez-Rellan, M.J. ; Fondevila, M.F. ; Fernandez, U. ; Rodriguez, A. ; Varela-Rey, M. ; Veyrat-Durebex, C. ; Seoane, S. ; Bernardo, G. ; Lopitz-Otsoa, F. ; Fernández-Ramos, D. ; Bilbao, J. ; Iglesias, C. ; Novoa, E. ; Ameneiro, C. ; Senra, A. ; Beiroa, D. ; Cuñarro, J. ; DP Chantada-Vazquez, M. ; Garcia-Vence, M. ; Bravo, S.B. ; Da Silva Lima, N. ; Porteiro, B. ; Carneiro, C. ; Vidal, A. ; Tovar, S. ; Müller, T.D. ; Ferno, J. ; Guallar, D. ; Fidalgo, M. ; Sabio, G. ; Herzig, S. ; Yang, W.H. ; Cho, J.W. ; Martínez-Chantar, M.L. ; Perez-Fernandez, R. ; López, M. ; Dieguez, C. ; Mato, J.M. ; Millet, O. ; Coppari, R. ; Woodhoo, A. ; Fruhbeck, G. ; Nogueiras, R.
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.Müller, T.D. ; Klingenspor, M. ; Tschöp, M.H.
Revisiting energy expenditure: How to correct mouse metabolic rate for body mass.Sander, P. ; Feng, M. ; Schweitzer, M.K. ; Wilting, F. ; Gutenthaler, S.M. ; Arduino, D.M. ; Fischbach, S. ; Dreizehnter, L. ; Moretti, A. ; Gudermann, T. ; Perocchi, F. ; Schredelseker, J.
Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis.Ajarem, J.S. ; Maodaa, S.N. ; El-Serehy, H.A. ; Altoom, N. ; Allam, A.A. ; Hernandez-Bautista, R. ; Mahmoud, A.M.
Anethum graveolens prevents liver and kidney injury, oxidative stress and inflammation in mice exposed to nicotine perinatally.Kabra, U. ; Affourtit, C. ; Jastroch, M.
Respiratory parameters for the classification of dysfunctional insulin secretion by pancreatic islets.Klaus, V. ; Schriever, S.C. ; Monroy Kuhn, J.M. ; Peter, A. ; Irmler, M. ; Tokarz, J. ; Prehn, C. ; Kastenmüller, G. ; Beckers, J. ; Adamski, J. ; Königsrainer, A. ; Müller, T.D. ; Heni, M. ; Tschöp, M.H. ; Pfluger, P.T. ; Lutter, D.
Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism.Lesch, S. ; Blumenberg, V. ; Stoiber, S. ; Gottschlich, A. ; Ogonek, J. ; Cadilha, B.L. ; Dantes, Z. ; Rataj, F. ; Dorman, K. ; Lutz, J. ; Karches, C.H. ; Heise, C. ; Kurzay, M. ; Larimer, B.M. ; Grassmann, S. ; Rapp, M. ; Nottebrock, A. ; Krüger, S. ; Tokarew, N. ; Metzger, P. ; Hoerth, C. ; Benmebarek, M.R. ; Dhoqina, D. ; Grünmeier, R. ; Seifert, M. ; Oener, A. ; Umut, Ö. ; Joaquina, S. ; Vimeux, L. ; Tran, T. ; Hank, T. ; Baba, T. ; Huynh, D. ; Megens, R.T.A. ; Janssen, K.P. ; Jastroch, M. ; Lamp, D. ; Ruehland, S. ; Di Pilato, M. ; Pruessmann, J.N. ; Thomas, M. ; Marr, C. ; Ormanns, S. ; Reischer, A. ; Hristov, M. ; Tartour, E. ; Donnadieu, E. ; Rothenfußer, S. ; Duewell, P. ; König, L.M. ; Schnurr, M. ; Subklewe, M. ; Liss, A.S. ; Halama, N. ; Reichert, M. ; Mempel, T.R. ; Endres, S. ; Kobold, S.
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.Arduino, D.M. ; Goh, V. ; Mokranjac, D. ; Perocchi, F.
Drug discovery assay to identify modulators of the mitochondrial Ca2+ uniporter.Luong, Q.V. ; Israel, A. ; Sharma, R. ; Ussar, S. ; Lee, K.Y.
Development of an optimized clearing protocol to examine adipocyte subpopulations in white adipose tissue.Chan, C.C. ; Pfluger, P.T. ; Trompette, A. ; Stankiewicz, T.E. ; Allen, J.L. ; Moreno-Fernandez, M.E. ; Damen, M.S.M.A. ; Oates, J.R. ; Alarcon, P.C. ; Doll, J.R. ; Flick, M.J. ; Flick, L.M. ; Sanchez-Gurmaches, J. ; Mukherjee, R. ; Karns, R. ; Helmrath, M. ; Inge, T.H. ; Weisberg, S.P. ; Pamp, S.J. ; Relman, D.A. ; Seeley, R.J. ; Karp, C.L. ; Divanovic, S.
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain.Dudek, M. ; Pfister, D. ; Donakonda, S. ; Filpe, P. ; Schneider, A. ; Laschinger, M. ; Hartmann, D. ; Hüser, N. ; Meiser, P. ; Bayerl, F. ; Inverso, D. ; Wigger, J. ; Sebode, M. ; Öllinger, R. ; Rad, R. ; Hegenbarth, S. ; Anton, M. ; Guillot, A. ; Bowman, A. ; Heide, D. ; Müller, F. ; Ramadori, P. ; Leone, V. ; García-Cáceres, C. ; Gruber, T. ; Seifert, G. ; Kabat, A.M. ; Mallm, J.P. ; Reider, S. ; Effenberger, M. ; Roth, S. ; Billeter, A.T. ; Müller-Stich, B. ; Pearce, E.J. ; Koch-Nolte, F. ; Käser, R. ; Tilg, H. ; Thimme, R. ; Boettler, T. ; Tacke, F. ; Dufour, J.F. ; Haller, D. ; Murray, P.J. ; Heeren, R. ; Zehn, D. ; Böttcher, J.P. ; Heikenwalder, M. ; Knolle, P.A.
Author Correction: Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.Stavsky, A. ; Stoler, O. ; Kostic, M. ; Katoshevsky, T. ; Assali, E.A. ; Savic, I. ; Amitai, Y. ; Prokisch, H. ; Leiz, S. ; Daumer-Haas, C. ; Fleidervish, I.A. ; Perocchi, F. ; Gitler, D. ; Sekler, I.
Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation.Huang, J. ; Linares, J.F. ; Duran, A. ; Xia, W. ; Saltiel, A.R. ; Müller, T.D. ; Diaz-Meco, M.T. ; Moscat, J.
NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ.Stavsky, A. ; Stoler, O. ; Kostic, M. ; Katoshevsky, T. ; Assali, E.A. ; Savic, I. ; Amitai, Y. ; Prokisch, H. ; Leiz, S. ; Daumer-Haas, C. ; Fleidervish, I.A. ; Perocchi, F. ; Gitler, D. ; Sekler, I.
Author Correction: Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation (Communications Biology, (2021), 4, 1, (666), 10.1038/s42003-021-02114-0).Monroy Kuhn, J.M. ; Meusemann, K. ; Korb, J.
Disentangling the aging gene expression network of termite queens.Sandin, E.S. ; Folberth, J. ; Müller-Fielitz, H. ; Pietrzik, C.U. ; Herold, E. ; Willnow, T.E. ; Pfluger, P.T. ; Nogueiras, R. ; Prévot, V. ; Schwaninger, M.
Is LRP2 involved in leptin transport over the blood-brain barrier and development of obesity?Brüning, J. ; García-Cáceres, C. ; Heni, M. ; Preissl, H.
Insulinwirkung und -resistenz im Gehirn.Georgiadi, A. ; Lopez Salazar, V. ; El-Merahbi, R. ; Karikari, R.A. ; Ma, X. ; Mourao, A. ; Klepac, K. ; Bühler, L. ; Alfaro, A.J. ; Kaczmarek, I. ; Linford, A. ; Bosma, M. ; Shilkova, O. ; Ritvos, O. ; Nakamura, N. ; Hirose, S. ; Lassi, M. ; Teperino, R. ; Machado, J. ; Scheideler, M. ; Dietrich, A. ; Geerlof, A. ; Feuchtinger, A. ; Blutke, A. ; Fischer, K. ; Müller, T.D. ; Kessler, K. ; Schöneberg, T. ; Thor, D. ; Hornemann, S. ; Kruse, M. ; Nawroth, P.P. ; Pivovarova-Ramich, O. ; Pfeiffer, A.F.H. ; Sattler, M. ; Blüher, M. ; Herzig, S.
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.Gonzales García, I. ; García-Cáceres, C.
Hypothalamic astrocytes as a specialized and responsive cell population in obesity.Gruber, T. ; Pan, C. ; Contreras, R. ; Wiedemann, T. ; Morgan, D.A. ; Skowronski, A.A. ; Lefort, S. ; De Bernardis Murat, C. ; Le Thuc, O. ; Legutko, B. ; Ruiz Ojeda, F.J. ; Fuente-Fernández, M. ; García-Villalón, A.L. ; González-Hedström, D. ; Huber, M. ; Szigeti-Buck, K. ; Müller, T.D. ; Ussar, S. ; Pfluger, P.T. ; Woods, S.C. ; Ertürk, A. ; LeDuc, C.A. ; Rahmouni, K. ; Granado, M. ; Horvath, T.L. ; Tschöp, M.H. ; García-Cáceres, C.
Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension.Reina-Pérez, I. ; Olivas-Martínez, A. ; Mustieles, V. ; Ruiz Ojeda, F.J. ; Molina-Molina, J.M. ; Olea, N. ; Fernández, M.F.
Bisphenol F and bisphenol S promote lipid accumulation and adipogenesis in human adipose-derived stem cells.Ecker, J. ; Benedetti, E. ; Kindt, A. ; Höring, M. ; Perl, M. ; Machmüller, A.C. ; Sichler, A. ; Plagge, J. ; Wang, Y. ; Zeissig, S. ; Shevchenko, A. ; Burkhardt, R. ; Krumsiek, J. ; Liebisch, G. ; Janssen, K.P.
The colorectal cancer lipidome - identification of a robust tumor-specific lipid species signature.Zeigerer, A. ; Sekar, R. ; Kleinert, M. ; Nason, S. ; Habegger, K.M. ; Müller, T.D.
Glucagon's metabolic action in health and disease.Repenning, A. ; Happel, D. ; Bouchard, C. ; Meixner, M. ; Verel-Yilmaz, Y. ; Raifer, H. ; Holembowski, L. ; Krause, E. ; Kremmer, E. ; Feederle, R. ; Keber, C.U. ; Lohoff, M. ; Slater, E.P. ; Bartsch, D.K. ; Bauer, U.M.
PRMT1 promotes the tumor suppressor function of p14ARF and is indicative for pancreatic cancer prognosis.Dudek, M. ; Pfister, D. ; Donakonda, S. ; Filpe, P. ; Schneider, A. ; Laschinger, M. ; Hartmann, D. ; Hüser, N. ; Meiser, P. ; Bayerl, F. ; Inverso, D. ; Wigger, J. ; Sebode, M. ; Öllinger, R. ; Rad, R. ; Hegenbarth, S. ; Anton, M. ; Guillot, A. ; Bowman, A. ; Heide, D. ; Müller, F. ; Ramadori, P. ; Leone, V. ; García-Cáceres, C. ; Gruber, T. ; Seifert, G. ; Kabat, A.M. ; Malm, J.P. ; Reider, S. ; Effenberger, M. ; Roth, S. ; Billeter, A.T. ; Müller-Stich, B. ; Pearce, E.J. ; Koch-Nolte, F. ; Käser, R. ; Tilg, H. ; Thimme, R. ; Böttler, T. ; Tacke, F. ; Dufour, J.F. ; Haller, D. ; Murray, P.J. ; Heeren, R. ; Zehn, D. ; Böttcher, J.P. ; Heikenwälder, M. ; Knolle, P.A.
Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.Müller, G. ; Lechner, A. ; Tschöp, M.H. ; Müller, T.D.
Interaction of full-length glycosylphosphatidylinositol-anchored proteins with serum proteins and their translocation to cells in vitro depend on the (Pre-)diabetic state in rats and humans.Gonzales García, I. ; Gruber, T. ; García-Cáceres, C.
Insulin action on astrocytes: From energy homeostasis to behaviour.Suwandhi, L. ; Altun, I. ; Karlina, R. ; Miok, V. ; Wiedemann, T. ; Fischer, D.S. ; Walzthoeni, T. ; Lindner, C. ; Böttcher, A. ; Heinzmann, S.S. ; Israel, A. ; Khalil, A. ; Braun, A. ; Pramme-Steinwachs, I. ; Burtscher, I. ; Schmitt-Kopplin, P. ; Heinig, M. ; Elsner, M. ; Lickert, H. ; Theis, F.J. ; Ussar, S.
Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population.Ansarullah ; Jain, C. ; Far, F.F. ; Homberg, S. ; Wißmiller, K. ; von Hahn, F. ; Raducanu, A. ; Schirge, S. ; Sterr, M. ; Bilekova, S. ; Siehler, J. ; Wiener, J. ; Oppenländer, L. ; Morshedi, A. ; Bastidas-Ponce, A. ; Collden, G. ; Irmler, M. ; Beckers, J. ; Feuchtinger, A. ; Grzybek, M. ; Ahlbrecht, C. ; Feederle, R. ; Plettenburg, O. ; Müller, T.D. ; Meier, M. ; Tschöp, M.H. ; Coskun, Ü. ; Lickert, H.
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.Anguita-Ruiz, A. ; Bustos-Aibar, M. ; Plaza-Díaz, J. ; Méndez-Gutiérrez, A. ; Alcalá-Fdez, J. ; Aguilera, C.M. ; Ruiz Ojeda, F.J.
Omics approaches in adipose tissue and skeletal muscle addressing the role of extracellular matrix in obesity and metabolic dysfunction.Klein, A.B. ; Nicolaisen, T.S. ; Ørtenblad, N. ; Gejl, K.D. ; Jensen, R. ; Fritzen, A.M. ; Larsen, E.L. ; Karstoft, K. ; Poulsen, H.E. ; Morville, T. ; Sahl, R.E. ; Helge, J.W. ; Lund, J. ; Falk, S. ; Lyngbæk, M. ; Ellingsgaard, H. ; Pedersen, B.K. ; Lu, W. ; Finan, B. ; Jørgensen, S.B. ; Seeley, R.J. ; Kleinert, M. ; Kiens, B. ; Richter, E.A. ; Clemmensen, C.
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise.Quarta, C. ; Claret, M. ; Zeltser, L.M. ; Williams, K.W. ; Yeo, G.S.H. ; Tschöp, M.H. ; Diano, S. ; Cota, D.
POMC neuronal heterogeneity in energy balance and beyond: An integrated view.Keipert, S. ; Lutter, D. ; Schroeder, B.O. ; Brandt, D. ; Ståhlman, M. ; Schwarzmayr, T. ; Graf, E. ; Fuchs, H. ; Hrabě de Angelis, M. ; Tschöp, M.H. ; Rozman, J. ; Jastroch, M.
Author Correction: Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice (Nature Communications, (2020), 11, 1, (624), 10.1038/s41467-019-14069-2).Delgado De La Herran, H.C. ; Cheng, Y. ; Perocchi, F.
Towards a systems-level understanding of mitochondrial biology.Herker, E. ; Vieyres, G. ; Beller, M. ; Krahmer, N. ; Bohnert, M.
Lipid droplet contact sites in health and disease.Gonzales García, I. ; Le Thuc, O. ; Jastroch, M. ; García-Cáceres, C.
Divide et impera: How mitochondrial fission in astrocytes rules obesity.Novikoff, A. ; O'Brien, S.L. ; Bernecker, M. ; Grandl, G. ; Kleinert, M. ; Knerr, P.J. ; Stemmer, K. ; Klingenspor, M. ; Zeigerer, A. ; DiMarchi, R. ; Tschöp, M.H. ; Finan, B. ; Calebiro, D. ; Müller, T.D.
Spatiotemporal GLP-1 and GIPR receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists.Assfalg, R. ; Knoop, J. ; Hoffman, K.L. ; Pfirrmann, M. ; Zapardiel-Gonzalo, J. ; Hofelich, A. ; Eugster, A. ; Weigelt, M. ; Matzke, C. ; Reinhardt, J. ; Fuchs, Y. ; Bunk, M. ; Weiss, A. ; Hippich, M. ; Halfter, K. ; Hauck, S.M. ; Hasford, J. ; Petrosino, J.F. ; Achenbach, P. ; Bonifacio, E. ; Ziegler, A.-G.
Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial.Li, Z.M. ; Miller, M. ; Gachkar, S. ; Mittag, J. ; Schriever, S.C. ; Pfluger, P.T. ; Schramm, K.-W. ; de Angelis, M.
Determination of 3-iodothyronamine (3-T1AM) in mouse liver using liquid chromatography-tandem mass spectrometry.Ruiz Ojeda, F.J. ; Wang, J. ; Bäcker, T. ; Krueger, M. ; Zamani, S. ; Rosowski, S. ; Gruber, T. ; Onogi, Y. ; Feuchtinger, A. ; Schulz, T.J. ; Fässler, R. ; Müller, T.D. ; García-Cáceres, C. ; Meier, M. ; Blüher, M. ; Ussar, S.
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.Ansarullah ; Jain, C. ; Far, F.F. ; Homberg, S. ; Wissmiller, K. ; Gräfin von Hahn, F. ; Raducanu, A. ; Schirge, S. ; Sterr, M. ; Bilekova, S. ; Siehler, J. ; Wiener, J. ; Oppenländer, L. ; Morshedi, A. ; Bastidas-Ponce, A. ; Collden, G. ; Irmler, M. ; Beckers, J. ; Feuchtinger, A. ; Grzybek, M. ; Ahlbrecht, C. ; Feederle, R. ; Plettenburg, O. ; Müller, T.D. ; Meier, M. ; Tschöp, M.H. ; Coskun, Ü. ; Lickert, H.
Inceptor counteracts insulin signalling in β-cells to control glycaemia.Zhang, Q. ; Delessa, C.T. ; Augustin, R. ; Bakhti, M. ; Collden, G. ; Drucker, D.J. ; Feuchtinger, A. ; García-Cáceres, C. ; Grandl, G. ; Harger, A. ; Herzig, S. ; Hofmann, S.M. ; Holleman, C.L. ; Jastroch, M. ; Keipert, S. ; Kleinert, M. ; Knerr, P.J. ; Kulaj, K. ; Legutko, B. ; Lickert, H. ; Liu, X. ; Luippold, G. ; Lutter, D. ; Malogajski, E. ; Tarquis Medina, M. ; Mowery, S.A. ; Blutke, A. ; Perez-Tilve, D. ; Salinno, C. ; Sehrer, L. ; DiMarchi, R.D. ; Tschöp, M.H. ; Stemmer, K. ; Finan, B. ; Wolfrum, C. ; Müller, T.D.
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.Hartleben, G. ; Schorpp, K.K. ; Kwon, Y. ; Betz, B. ; Tsokanos, F.-F. ; Dantes, Z. ; Schäfer, A. ; Rothenaigner, I. ; Monroy Kuhn, J.M. ; Morigny, P. ; Mehr, L. ; Lin, S. ; Seitz, S. ; Tokarz, J. ; Artati, A. ; Adamski, J. ; Plettenburg, O. ; Lutter, D. ; Irmler, M. ; Beckers, J. ; Reichert, M. ; Hadian, K. ; Zeigerer, A. ; Herzig, S. ; Berriel Diaz, M.
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism.Bilekova, S. ; Sachs, S. ; Lickert, H.
Pharmacological targeting of endoplasmic reticulum stress in pancreatic beta cells.Lundsgaard, A.M. ; Fritzen, A.M. ; Sjøberg, K.A. ; Kleinert, M. ; Richter, E.A. ; Kiens, B.
Small amounts of dietary medium-chain fatty acids protect against insulin resistance during caloric excess in humans.Hippich, M. ; Holthaus, L. ; Assfalg, R. ; Zapardiel-Gonzalo, J. ; Kapfelsperger, H. ; Heigermoser, M. ; Haupt, F. ; Ewald, D.A. ; Welzhofer, T.C. ; Marcus, B.A. ; Heck, S. ; Koelln, A. ; Stock, J. ; Voss, F. ; Secchi, M. ; Piemonti, L. ; Rosa, K. ; Protzer, U. ; Boehmer, M. ; Achenbach, P. ; Lampasona, V. ; Bonifacio, E. ; Ziegler, A.-G.
Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children.Ziegler, A.-G. ; Bonifacio, E.
Shortening the paths to type 1 diabetes mellitus prevention.Karlina, R. ; Lutter, D. ; Miok, V. ; Fischer, D.S. ; Altun, I. ; Schöttl, T. ; Schorpp, K.K. ; Israel, A. ; Cero, C. ; Johnson, J.W. ; Kapser-Fischer, I. ; Böttcher, A. ; Keipert, S. ; Feuchtinger, A. ; Graf, E. ; Strom, T.M. ; Walch, A.K. ; Lickert, H. ; Walzthoeni, T. ; Heinig, M. ; Theis, F.J. ; García-Cáceres, C. ; Cypess, A.M. ; Ussar, S.
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.Sachs, S. ; Niu, L. ; Geyer, P. ; Jall, S. ; Kleinert, M. ; Feuchtinger, A. ; Stemmer, K. ; Brielmeier, M. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Wewer Albrechtsen, N. ; Mann, M. ; Müller, T.D. ; Hofmann, S.M.
Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice.Baumann, P. ; Schriever, S.C. ; Kullmann, S. ; Zimprich, A. ; Peter, A. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Wurst, W. ; Tschöp, M.H. ; Heni, M. ; Hölter, S.M. ; Pfluger, P.T.
Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.Schraut, K.G. ; Kalnytska, O. ; Lamp, D. ; Jastroch, M. ; Eder, M. ; Hausch, F. ; Gassen, N.C. ; Moore, S. ; Nagaraj, N. ; Lopez, J.P. ; Chen, A. ; Schmidt, M.V.
Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons.von Gamm, M.
Myeloid cells require the ribonuclease Regnase-3 for immune homeostasis and balanced interferon responses in vivo.Willmann, C. ; Brockmann, K. ; Wagner, R. ; Kullmann, S. ; Heni, M. ; Schnauder, G. ; Maetzler, W. ; Gasser, T. ; Berg, D. ; Eschweiler, G.W. ; Metzger, F. ; Fallgatter, A.J. ; Häring, H.-U. ; Fritsche, A.
Insulin sensitivity predicts cognitive decline in individuals with prediabetes.Kullmann, S. ; Abbas, Z. ; Machann, J. ; Scheffler, K. ; Birkenfeld, A.L. ; Häring, H.-U. ; Fritsche, A. ; Heni, M.
Investigating obesity-associated brain inflammation using quantitative water content mapping.Lampl, S. ; Janas, M.K. ; Donakonda, S. ; Brugger, M. ; Lohr, K. ; Schneider, A. ; Manske, K. ; Sperl, L.E. ; Kläger, S. ; Küster, B. ; Wettmarshausen, J. ; Müller, C. ; Laschinger, M. ; Hartmann, D. ; Hüser, N. ; Perocchi, F. ; Schmitt-Kopplin, P. ; Hagn, F. ; Zender, L. ; Hornung, V. ; Borner, C. ; Pichlmair, A. ; Kashkar, H. ; Klingenspor, M. ; Prinz, M. ; Schreiner, S. ; Conrad, M. ; Jost, P.J. ; Zischka, H. ; Steiger, K. ; Krönke, M. ; Zehn, D. ; Protzer, U. ; Heikenwälder, M. ; Knolle, P.A. ; Wohlleber, D.
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.Meissner, K. ; Lutter, D. ; von Toerne, C. ; Haile, A. ; Woods, S.C. ; Hoffmann, V. ; Ohmayer, U. ; Hauck, S.M. ; Tschöp, M.H.
Molecular classification of the placebo effect in nausea.Klymenko, O. ; Brecklinghaus, T. ; Dille, M. ; Springer, C. ; de Wendt, C. ; Altenhofen, D. ; Binsch, C. ; Knebel, B. ; Scheller, J. ; Hardt, C. ; Herwig, R. ; Chadt, A. ; Pfluger, P.T. ; Al-Hasani, H. ; Kabra, D.G.
Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle.Schleger, F. ; Fritsche, L. ; Birkenfeld, A.L. ; Heni, M. ; Fritsche, A.
Materner Metabolismus und fetale Entwicklung.Pittis, A.A. ; Goh, V. ; Cebrian Serrano, A. ; Wettmarshausen, J. ; Perocchi, F. ; Gabaldón, T.
Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter.Schwerbel, K. ; Kamitz, A. ; Krahmer, N. ; Hallahan, N. ; Jähnert, M. ; Gottmann, P. ; Lebek, S. ; Schallschmidt, T. ; Arends, D. ; Schumacher, F. ; Kleuser, B. ; Haltenhof, T. ; Heyd, F. ; Gancheva, S. ; Broman, K.W. ; Roden, M. ; Joost, H.G. ; Chadt, A. ; Al-Hasani, H. ; Vogel, H. ; Jonas, W. ; Schürmann, A.
Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation.Cinque, L. ; De Leonibus, C. ; Iavazzo, M. ; Krahmer, N. ; Intartaglia, D. ; Salierno, F.G. ; De Cegli, R. ; Di Malta, C. ; Svelto, M. ; Lanzara, C. ; Maddaluno, M. ; Wanderlingh, L.G. ; Huebner, A.K. ; Cesana, M. ; Bonn, F. ; Polishchuk, E. ; Hübner, C.A. ; Conte, I. ; Dikic, I. ; Mann, M. ; Ballabio, A. ; Sacco, F. ; Grumati, P. ; Settembre, C.
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B.Kleinert, M. ; Müller, T.D.
A new FGF21 analog for the treatment of fatty liver disease.Müller, G. ; Ussar, S. ; Tschöp, M.H. ; Müller, T.D.
Age-dependent membrane release and degradation of full-length glycosylphosphatidylinositol-anchored proteins in rats.Meul, T. ; Berschneider, K. ; Schmitt, S. ; Mayr, C. ; Mattner, L. ; Schiller, H. B. ; Yazgili, A.S. ; Wang, X. ; Lukas, C. ; Schlesser, C. ; Prehn, C. ; Adamski, J. ; Graf, E. ; Schwarzmayr, T. ; Perocchi, F. ; Kukat, A. ; Trifunovic, A. ; Kremer, L.S. ; Prokisch, H. ; Popper, B. ; von Toerne, C. ; Hauck, S.M. ; Zischka, H. ; Meiners, S.
Mitochondrial regulation of the 26S proteasome.Ladwig, K.-H. ; Schriever, S.C. ; Atasoy, S. ; Bidlingmaier, M. ; Kruse, J. ; Johar, H.
Association of generalized and central obesity with serum and salivary cortisol secretion patterns in the elderly: Findings from the cross sectional KORA-Age study.Blutke, A. ; Sun, N. ; Xu, Z. ; Buck, A. ; Harrison, L. ; Schriever, S.C. ; Pfluger, P.T. ; Wiles, D. ; Kunzke, T. ; Huber, K. ; Schlegel, J. ; Aichler, M. ; Feuchtinger, A. ; Matiasek, K. ; Hauck, S.M. ; Walch, A.K.
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples.Onogi, Y. ; Khalil, A. ; Ussar, S.
Identification and characterization of adipose surface epitopes.Schriever, S.C. ; Kabra, D.G. ; Pfuhlmann, K. ; Baumann, P. ; Baumgart, E.V. ; Nagler, J. ; Seebacher, F. ; Harrison, L. ; Irmler, M. ; Kullmann, S. ; Corrêa-da-Silva, F. ; Giesert, F. ; Jain, R. ; Schug, H. ; Castel, J. ; Martinez, S. ; Wu, M. ; Häring, H.-U. ; Hrabě de Angelis, M. ; Beckers, J. ; Müller, T.D. ; Stemmer, K. ; Wurst, W. ; Rozman, J. ; Nogueiras, R. ; de Angelis, M. ; Molkentin, J.D. ; Krahmer, N. ; Yi, C.-X. ; Schmidt, M.V. ; Luquet, S. ; Heni, M. ; Tschöp, M.H. ; Pfluger, P.T.
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.Simon, J.J. ; Stopyra, M.A. ; Mönning, E. ; Sailer, S. ; Lavandier, N. ; Kihm, L.P. ; Bendszus, M. ; Preissl, H. ; Herzog, W. ; Friederich, H.C.
Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity.Escoter Torres, L. ; Greulich, F. ; Quagliarini, F. ; Wierer, M. ; Uhlenhaut, N.H.
Anti-inflammatory functions of the glucocorticoid receptor require DNA binding.Stemmer, K. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Müller, T.D.
Insights into incretin-based therapies for treatment of diabetic dyslipidemia.Hampe, C.S. ; Sahabandu, D. ; Kaiser, V. ; Telieps, T. ; Smeeth, L. ; Agyemang, C. ; Spranger, J. ; Schulze, M.B. ; Mockenhaupt, F.P. ; Danquah, I. ; Rolandsson, O.
Geographic location determines beta-cell autoimmunity among adult Ghanaians: Findings from the RODAM study.Elgebaly, H. ; Germoush, M. ; Mosa, N. ; Zahou, F. ; Soffar, A. ; Alotaibi, N. ; Qarmush, M. ; Hussein, O. ; Bin-Jumah, M. ; Hassanein, E. ; Hernandez-Bautista, R. ; Mahmoud, A.M.
Adenium obesum flowers extract mitigates testicular injury and oxidative stress in streptozotocin-induced diabetic rats.Abukhalil, M.H. ; Hussein, O.E. ; Bin-Jumah, M. ; Saghir, S.A.M. ; Germoush, M.O. ; Elgebaly, H.A. ; Mosa, N.M. ; Hamad, I. ; Qarmush, M.M. ; Hassanein, E.M. ; Kamel, E.M. ; Hernandez-Bautista, R. ; Mahmoud, A.M.
Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats.Seebacher, F. ; Zeigerer, A. ; Kory, N. ; Krahmer, N.
Hepatic lipid droplet homeostasis and fatty liver disease.Fritzen, A.M. ; Domingo-Espín, J. ; Lundsgaard, A.M. ; Kleinert, M. ; Israelsen, I. ; Carl, C.S. ; Nicolaisen, T.S. ; Kjøbsted, R. ; Jeppesen, J.F. ; Wojtaszewski, J.F.P. ; Lagerstedt, J.O. ; Kiens, B.
ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2.Fischer, K. ; Fenzl, A. ; Liu, D. ; Dyar, K.A. ; Kleinert, M. ; Brielmeier, M. ; Clemmensen, C. ; Fedl, A. ; Finan, B. ; Gessner, A. ; Jastroch, M. ; Huang, J. ; Keipert, S. ; Klingenspor, M. ; Brüning, J.C. ; Kneilling, M. ; Maier, F.C. ; Othman, A.E. ; Pichler, B.J. ; Pramme-Steinwachs, I. ; Sachs, S. ; Scheideler, A. ; Thaiss, W.M. ; Uhlenhaut, N.H. ; Ussar, S. ; Woods, S.C. ; Zorn, J. ; Stemmer, K. ; Collins, S. ; Diaz-Meco, M. ; Moscat, J. ; Tschöp, M.H. ; Müller, T.D.
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.Sachs, S. ; Bastidas-Ponce, A. ; Tritschler, S. ; Bakhti, M. ; Böttcher, A. ; Sánchez-Garrido, M.A. ; Tarquis Medina, M. ; Kleinert, M. ; Fischer, K. ; Jall, S. ; Harger, A. ; Bader, E. ; Roscioni, S. ; Ussar, S. ; Feuchtinger, A. ; Yesildag, B. ; Neelakandhan, A. ; Jensen, C.B. ; Cornu, M. ; Yang, B. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Theis, F.J. ; Hofmann, S.M. ; Müller, T.D. ; Lickert, H.
Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission (Nature Metabolism, (2020), 2, 2, (192-209), 10.1038/s42255-020-0171-3).Berland, C. ; Montalban, E. ; Perrin, E. ; Di Miceli, M. ; Nakamura, Y. ; Martinat, M. ; Sullivan, M. ; Davis, X.S. ; Shenasa, M.A. ; Martin, C. ; Tolu, S. ; Marti, F. ; Caille, S. ; Castel, J. ; Perez, S. ; Salinas, C.G. ; Morel, C. ; Hecksher-Sørensen, J. ; Cador, M. ; Fioramonti, X. ; Tschöp, M.H. ; Layé, S. ; Venance, L. ; Faure, P. ; Hnasko, T.S. ; Small, D.M. ; Gangarossa, G. ; Luquet, S.H.
Circulating triglycerides gate dopamine-associated behaviors through DRD2-expressing neurons.de Angelis, M. ; Schriever, S.C. ; Kyriakou, E. ; Sattler, M. ; Messias, A.C. ; Schramm, K.-W. ; Pfluger, P.T.
Detection and quantification of the anti-obesity drug celastrol in murine liver and brain.Plaza-Díaz, J. ; Pastor-Villaescusa, B. ; Rueda-Robles, A. ; Abadia-Molina, F. ; Ruiz Ojeda, F.J.
Plausible biological interactions of low- and non-calorie sweeteners with the intestinal microbiota: An update of recent studies.Krude, H. ; Biebermann, H. ; Schuelke, M. ; Müller, T.D. ; Tschöp, M.H.
Allan-herndon-dudley-syndrome: Considerations about the brain phenotype with implications for treatment strategies.Jastroch, M. ; Ussar, S. ; Keipert, S.
Gut microbes controlling blood sugar: No fire required!Jall, S. ; de Angelis, M. ; Lundsgaard, A.M. ; Fritzen, A.M. ; Nicolaisen, T.S. ; Klein, A.B. ; Novikoff, A. ; Sachs, S. ; Richter, E.A. ; Kiens, B. ; Schramm, K.-W. ; Tschöp, M.H. ; Stemmer, K. ; Clemmensen, C. ; Müller, T.D. ; Kleinert, M.
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity.Ziegler, A.-G. ; Kick, K. ; Bonifacio, E. ; Haupt, F. ; Hippich, M. ; Dunstheimer, D. ; Lang, M. ; Laub, O. ; Warncke, K. ; Lange, K. ; Assfalg, R. ; Jolink, M. ; Winkler, C. ; Achenbach, P.
Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany.Müller, G. ; Herling, A.W. ; Wied, S. ; Müller, T.D.
CB1 receptor-dependent and independent induction of lipolysis in primary rat adipocytes by the inverse agonist rimonabant (SR141716A).Sander, P. ; Arduino, D.M. ; Wilting, F. ; Schweitzer, M. ; Gudermann, T. ; Perocchi, F. ; Schredelseker, J.
Novel mitochondrial Ca2+ enhancers for the treatment of cardiac arrhythmia.Müller, G. ; Tschöp, M.H. ; Müller, T.D.
Upregulated phospholipase D activity toward glycosylphosphatidylinositol-anchored proteins in micelle-like serum complexes in metabolically deranged rats and humans.Müller, T.D. ; Habegger, K.
Revisiting the pharmacological value of glucagon: An editorial for the special Issue "The biology and pharmacology of glucagon".Knoop, J. ; Eugster, A. ; Gavrisan, A. ; Lickert, R. ; Sedlmeier, E.-M. ; Dietz, S. ; Lindner, A. ; Warncke, K. ; Hummel, N. ; Ziegler, A.-G. ; Bonifacio, E.
Maternal type 1 diabetes reduces autoantigen-responsive CD4(+) T cells in Offspring.Sachs, S. ; Bastidas-Ponce, A. ; Tritschler, S. ; Bakhti, M. ; Böttcher, A. ; Sánchez-Garrido, M.A. ; Tarquis Medina, M. ; Kleinert, M. ; Fischer, K. ; Jall, S. ; Harger, A. ; Bader, E. ; Roscioni, S. ; Ussar, S. ; Feuchtinger, A. ; Yesildag, B. ; Neelakandhan, A. ; Jensen, C.B. ; Cornu, M. ; Yang, B. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Theis, F.J. ; Hofmann, S.M. ; Müller, T.D. ; Lickert, H.
Targeted pharmacological therapy restores β-cell function for diabetes remission.Keipert, S. ; Lutter, D. ; Schroeder, B.O. ; Brandt, D. ; Ståhlman, M. ; Schwarzmayr, T. ; Graf, E. ; Fuchs, H. ; Hrabě de Angelis, M. ; Tschöp, M.H. ; Rozman, J. ; Jastroch, M.
Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice.Gonzales García, I. ; Milbank, E. ; Martinez-Ordoñez, A. ; Diéguez, C. ; López, M. ; Contreras, C.
HYPOTHesizing about central comBAT against obesity.Tan, Q. ; Orsso, C.E. ; Deehan, E.C. ; Triador, L. ; Field, C.J. ; Tun, H.M. ; Han, J.C. ; Müller, T.D. ; Haqq, A.M.
Current and emerging therapies for managing hyperphagia and obesity in Prader-Willi syndrome: A narrative review.Lundsgaard, A.M. ; Fritzen, A.M. ; Nicolaisen, T.S. ; Carl, C.S. ; Sjøberg, K.A. ; Raun, S.H. ; Klein, A.B. ; Sánchez Quant, E.S. ; Langer, J. ; Ørskov, C. ; Clemmensen, C. ; Tschöp, M.H. ; Richter, E.A. ; Kiens, B. ; Kleinert, M.
Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation.Knerr, P.J. ; Mowery, S.A. ; Finan, B. ; Perez-Tilve, D. ; Tschöp, M.H. ; DiMarchi, R.D.
Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates.Naranjo, V. ; Contreras, A. ; Merino, B. ; Plaza, A. ; Lorenzo, M.P. ; García-Cáceres, C. ; García, A. ; Chowen, J.A. ; Ruiz-Gayo, M. ; Del Olmo, N. ; Cano, V.
Specific deletion of the astrocyte leptin receptor induces changes in hippocampus glutamate metabolism, synaptic transmission and plasticity.Knudsen, J.R. ; Fritzen, A.M. ; James, D.E. ; Jensen, T.E. ; Kleinert, M. ; Richter, E.A.
Growth factor-dependent and -independent activation of mTORC2.Müller, G.
Membrane insertion and intercellular transfer of glycosylphosphatidylinositol-anchored proteins: potential therapeutic applications.Fischer, K. ; Müller, T.D.
Endocrine mechanisms in obesity.Müller, G.
Insulin-like and mimetic molecules from non-mammalian organisms: Potential relevance for drug discovery.Grandl, G. ; Novikoff, A. ; DiMarchi, R. ; Tschöp, M.H. ; Müller, T.D.
Gut peptide agonism in the treatment of obesity and diabetes.Kleinert, M. ; Müller, T.D.
Teaching an old dog new tricks: metformin induces body-weight loss via GDF15.Molocea, C.-E. ; Schmidt, S.F. ; Krahmer, N. ; Herzig, S. ; Diaz, M.B.
Exploring the contribution of the liver to cancer cachexia development.Contreras, R. ; Schriever, S.C. ; Pfluger, P.T.
Physiological and epigenetic features of yoyo dieting and weight control.Papadopoulou, A.A. ; Müller, S.A. ; Mentrup, T. ; Shmueli, M.D. ; Niemeyer, J. ; Haug-Kröper, M. ; von Blume, J. ; Mayerhofer, A. ; Feederle, R. ; Schröder, B. ; Lichtenthaler, S.F. ; Fluhrer, R.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.Baumann, P. ; Schriever, S.C. ; Kullmann, S. ; Zimprich, A. ; Feuchtinger, A. ; Amarie, O.V. ; Peter, A. ; Walch, A.K. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Wurst, W. ; Tschöp, M.H. ; Heni, M. ; Hölter, S.M. ; Pfluger, P.T.
Dusp8 affects hippocampal size and behavior in mice and humans.Aichner, S. ; Haile, A. ; Hoffmann, V. ; Olliges, E. ; Tschöp, M.H. ; Meissner, K.
The role of tactile stimulation for expectation, perceived treatment assignment and the placebo effect in an experimental nausea paradigm.Herrera Moro Chao, D. ; Wang, Y. ; Foppen, E. ; Ottenhoff, R. ; van Roomen, C. ; Parlevliet, E.T. ; van Eijk, M.J.T. ; Verhoek, M. ; Boot, R. ; Marques, A.R. ; Scheij, S. ; Mirzaian, M. ; Kooijman, S. ; Jansen, K. ; Wang, D. ; Mergen, C. ; Seeley, R.J. ; Tschöp, M.H. ; Overkleeft, H. ; Rensen, P.C.N. ; Kalsbeek, A. ; Aerts, J.M.F.G. ; Yi, C.X.
The iminosugar AMP-DNM improves satiety and activates brown adipose tissue through GLP1.Fuchs, Y.F. ; Sharma, V. ; Eugster, A. ; Kraus, G. ; Morgenstern, R. ; Dahl, A. ; Reinhardt, S. ; Petzold, A. ; Lindner, A. ; Löbel, D. ; Bonifacio, E.
Gene expression-based identification of antigen-responsive CD8+ T cells on a single-cell level.Jall, S. ; Finan, B. ; Collden, G. ; Fischer, K. ; Dong, X. ; Tschöp, M.H. ; Müller, T.D. ; Clemmensen, C.
Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice (vol 23, pg 75, 2019).Kleinert, M. ; Kotzbeck, P. ; Altendorfer-Kroath, T. ; Birngruber, T. ; Tschöp, M.H. ; Clemmensen, C.
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood-brain barrier in leptin resistant mice (vol 13, pg 77, 2018).Quagliarini, F. ; Mir, A.A. ; Balazs, K. ; Wierer, M. ; Dyar, K.A. ; Jouffe, C. ; Makris, K. ; Hawe, J. ; Heinig, M. ; Filipp, F.V. ; Barish, G.D. ; Uhlenhaut, N.H.
Cistromic reprogramming of the diurnal glucocorticoid hormone response by high-fat diet.Kleinert, M. ; Sachs, S. ; Habegger, K.M. ; Hofmann, S.M. ; Müller, T.D.
Glucagon regulation of energy expenditure.Bäckhed, F. ; Bugianesi, E. ; Christofk, H. ; Dikic, I. ; Gupta, R. ; Mair, W.B. ; O’Neill, L.A.J. ; Ralser, M. ; Sabatini, D.M. ; Tschöp, M.H.
The next decade of metabolism.Müller, T.D. ; Finan, B. ; Bloom, S.R. ; D'Alessio, D. ; Drucker, D.J. ; Flatt, P.R. ; Fritsche, A. ; Gribble, F. ; Grill, H.J. ; Habener, J.F. ; Holst, J.J. ; Langhans, W. ; Meier, J.J. ; Nauck, M.A. ; Perez-Tilve, D. ; Pocai, A. ; Reimann, F. ; Sandoval, D.A. ; Schwartz, T.W. ; Seeley, R.J. ; Stemmer, K. ; Tang-Christensen, M. ; Woods, S.C. ; DiMarchi, R.D. ; Tschöp, M.H.
Glucagon-like peptide 1 (GLP-1).Seitz, S. ; Kwon, Y. ; Hartleben, G. ; Jülg, J. ; Sekar, R. ; Krahmer, N. ; Najafi, B. ; Loft, A. ; Gancheva, S. ; Stemmer, K. ; Feuchtinger, A. ; Hrabě de Angelis, M. ; Müller, T.D. ; Mann, M. ; Blüher, M. ; Roden, M. ; Berriel Diaz, M. ; Behrends, C. ; Gilleron, J. ; Herzig, S. ; Zeigerer, A.
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.Grandoch, M. ; Flögel, U. ; Virtue, S. ; Maier, J.K. ; Jelenik, T. ; Kohlmorgen, C. ; Feldmann, K. ; Ostendorf, Y. ; Castañeda, T.R. ; Zhou, Z. ; Yamaguchi, Y. ; Nascimento, E.B.M. ; Sunkari, V.G. ; Goy, C. ; Kinzig, M. ; Sörgel, F. ; Bollyky, P.L. ; Schrauwen, P. ; Al-Hasani, H. ; Roden, M. ; Keipert, S. ; Vidal-Puig, A. ; Jastroch, M. ; Haendeler, J. ; Fischer, J.W.
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue.Klymenko, O. ; Brecklinghaus, T. ; Dille, M. ; Springer, C. ; de Wendt, C. ; Altenhofen, D. ; Knebel, B. ; Chadt, A. ; Pfluger, P.T. ; Al-Hasani, H. ; Kabra, D.
HDAC5 regulates IL-6 transcription and enhances insulin signalling in skeletal muscle.Díaz, J.P. ; Ruiz Ojeda, F.J. ; Lara, M.J.S. ; Gil, Á.
Edulcorantes y microbiota.Ruiz Ojeda, F.J. ; Méndez-Gutiérrez, A. ; Aguilera, C.M. ; Plaza-Díaz, J.
Extracellular matrix remodeling of adipose Ttssue in obesity and metabolic diseases.Fecher, C. ; Trovò, L. ; Müller, S.A. ; Snaidero, N. ; Wettmarshausen, J. ; Heink, S. ; Ortiz, O. ; Wagner, I. ; Kühn, R. ; Hartmann, J. ; Karl, R.M. ; Konnerth, A. ; Korn, T. ; Wurst, W. ; Merkler, D. ; Lichtenthaler, S.F. ; Perocchi, F. ; Misgeld, T.
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.Becker, M. ; Serr, I. ; Salb, V.K. ; Ott, V. ; Mengel, L. ; Blüher, M. ; Weigmann, B. ; Hauner, H. ; Tschöp, M.H. ; Daniel, C.
Short-term cold exposure supports human Treg induction in vivo.Glantschnig, C. ; Mattijssen, F. ; Vogl, E.S. ; Ali Khan, A. ; Rios Garcia, M. ; Fischer, K. ; Müller, T.D. ; Uhlenhaut, N.H. ; Nawroth, P.P. ; Scheideler, M. ; Rose, A.J. ; Pellegata, N.S. ; Herzig, S.
The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis.Stangl, A. ; Elliott, P.R. ; Pinto-Fernandez, A. ; Bonham, S. ; Harrison, L. ; Schaub, A. ; Kutzner, K. ; Keusekotten, K ; Pfluger, P.T. ; El Oualid, F. ; Kessler, B.M. ; Komander, D. ; Krappmann, D.
Regulation of the endosomal SNX27-retromer by OTULIN.Müller, G. ; Wied, S. ; Herling, A.W.
Analysis of direct effects of the CB1 receptor antagonist rimonabant on fatty acid oxidation and glycogenolysis in liver and muscle cells in vitro.Körner, A. ; Tschöp, M.H. ; Blüher, M.
Five-year outcomes of gastric bypass in adolescents as compared with adults.Giuranna, J. ; Jall, S. ; Peters, T. ; Hebebrand, J. ; Müller, T.D. ; Hinney, A.
Genetic and gene expression analysis in CTBP2: A gene derived from genome-wide data in anorexia nervosa and body weight regulation.Stemmer, K. ; Müller, T.D. ; DiMarchi, R.D. ; Pfluger, P.T. ; Tschöp, M.H.
CNS-targeting pharmacological interventions for the metabolic syndrome.Huertas, J.R. ; Ruiz Ojeda, F.J. ; Plaza-Díaz, J. ; Nordsborg, N.B. ; Martín-Albo, J. ; Rueda-Robles, A. ; Casuso, R.A.
Human muscular mitochondrial fusion in athletes during exercise.Gonzales García, I. ; Milbank, E. ; Diéguez, C. ; López, M. ; Contreras, C.
Glucagon, GLP-1 and thermogenesis.Krahmer, N. ; Mann, M.
Catching lipid droplet contacts by proteomics.Anguita-Ruiz, A. ; Plaza-Díaz, J. ; Ruiz Ojeda, F.J. ; Rupérez, A.I. ; Leis, R. ; Bueno, G. ; Gil-Campos, M. ; Vázquez-Cobela, R. ; Cañete, R. ; Moreno, L.A. ; Gil, A. ; Aguilera, C.M.
X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline.Harger, A. ; Stemmer, K. ; Tschöp, M.H. ; Müller, T.D.
Incretin-based co- and tri-agonists Innovative polypharmacology for the treatment of obesity and diabetes.Straub, L.G. ; Efthymiou, V. ; Grandl, G. ; Balaz, M. ; Challa, T.D. ; Truscello, L. ; Horvath, C. ; Moser, C. ; Rachamin, Y. ; Arnold, M. ; Sun, W. ; Modica, S. ; Wolfrum, C.
Antioxidants protect against diabetes by improving glucose homeostasis in mouse models of inducible insulin resistance and obesity.Klepac, K. ; Georgiadi, A. ; Tschöp, M.H. ; Herzig, S.
The role of brown and beige adipose tissue in glycaemic control.Karches, C.H. ; Benmebarek, M.R. ; Schmidbauer, M.L. ; Kurzay, M. ; Klaus, R. ; Geiger, M. ; Rataj, F. ; Cadilha, B.L. ; Lesch, S. ; Heise, C. ; Murr, R. ; vom Berg, J. ; Jastroch, M. ; Lamp, D. ; Ding, J. ; Duewell, P. ; Niederfellner, G. ; Sustmann, C. ; Endres, S. ; Klein, C. ; Kobold, S.
Bispecific antibodies enable synthetic agonistic receptor-transduced T cells for tumor immunotherapy.Bierbaumer, D. ; Muench, S. ; Haller, B. ; Habermehl, D. ; Pfluger, P.T. ; Stemmer, K. ; Combs, S.E.
Impact of diabetes on outcome and toxicity of neoadjuvant (chemo)radiation for rectal cancer.Bierbaumer, D. ; Muench, S. ; Haller, B. ; Habermehl, D. ; Pfluger, P.T. ; Stemmer, K. ; Combs, S.E.
Impact of diabetes on outcome and toxicity of chemoradiation for esophageal squamous cell carcinoma.Duma, M.N. ; Oszfolk, N.I. ; Boeckh-Behrens, T. ; Oechsner, M. ; Zimmer, C. ; Meyer, B. ; Pfluger, P.T. ; Combs, S.E.
Positive correlation between blood glucose and radiotherapy doses to the central gustatory system in Glioblastoma Multiforme patients.von Gamm, M. ; Schaub, A. ; Jones, A. ; Wolf, C. ; Behrens, G. ; Lichti, J. ; Essig, K. ; Macht, A. ; Pircher, J. ; Ehrlich, A. ; Davari, K. ; Chauhan, D. ; Busch, B. ; Wurst, W. ; Feederle, R. ; Feuchtinger, A. ; Tschöp, M.H. ; Friedel, C.C. ; Hauck, S.M. ; Sattler, M. ; Geerlof, A. ; Hornung, V. ; Heissmeyer, V. ; Schulz, C. ; Heikenwalder, M. ; Glasmacher, E.
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.Costa, M. ; Rosa, F. ; Ribeiro, T. ; Hernandez-Bautista, R. ; Bonaldo, M. ; Gonçalves Silva, N. ; Eiríksson, F. ; Thorsteinsdóttir, M. ; Ussar, S. ; Urbatzka, R.
Identification of cyanobacterial strains with potential for the treatment of obesity-related co- morbidities by bioactivity, toxicity evaluation and metabolite profiling.Schriever, S.C. ; Klaus, V. ; Lutter, D. ; Pfluger, P.T.
Diffenrential effects of weight loss by calorie restriction vs. exendin-4 on liver metabolism and eWAT inflammation.Ruiz Ojeda, F.J. ; Wang, J. ; Ussar, S.
Adipose selective loss of Kindlin-2 causes a lean insulin resistance phenotype.Liu, X. ; Ruiz Ojeda, F.J. ; Schöttl, T. ; Ussar, S.
Beta cell specific loss of serine racemase causes hyperinsulinemia independent of insulin secretion.Xu, Y. ; Borcherding, A.F. ; Heier, C. ; Tian, G. ; Roeder, T. ; Kühnlein, R.P.
Chronic dysfunction of Stromal interaction molecule by pulsed RNAi induction in fat tissue impairs organismal energy homeostasis in Drosophila.Müller, G. ; Herling, A.W. ; Stemmer, K. ; Lechner, A. ; Tschöp, M.H.
Chip-based sensing for release of unprocessed cell surface proteins in vitro and in serum and its (patho)physiological relevance.Benmebarek, M. ; Karches, C.H. ; Schmidbauer, M.L. ; Kurzay, M. ; Klaus, R. ; Geiger, M. ; Rataj, F. ; Cadilha, B. ; Lesch, S. ; Heise, C. ; Murr, R. ; vom Berg, J. ; Jastroch, M. ; Lamp, D. ; Niederfellner, G. ; Sustmann, C. ; Endres, S. ; Klein, C. ; Kobold, S.
Characterization of bispecific antibodies that drive synthetic agonistic receptor - transduced T cells to mediate specific and conditional therapy in human pancreatic cancer models.Gaudry, M.J. ; Campbell, K.L. ; Jastroch, M.
Evolution of UCP1.Harrison, L. ; Pfuhlmann, K. ; Schriever, S.C. ; Pfluger, P.T.
Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice.Bastek, H. ; Zubel, T. ; Stemmer, K. ; Mangerich, A. ; Beneke, S. ; Dietrich, D.R.
Comparison of Aristolochic acid I derived DNA adduct levels in human renal toxicity models.Décarie-Spain, L. ; Fisette, A. ; Zhu, Z. ; Yang, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Finan, B. ; Fulton, S. ; Clemmensen, C.
GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice.Tschöp, M.H.
Toward neuroendocrine precision medicines for metabolic diseases.Ratner, C. ; He, Z. ; Grunddal, K.V. ; Skov, L.J. ; Hartmann, B. ; Zhang, F. ; Feuchtinger, A. ; Bjerregaard, A. ; Christoffersen, C. ; Tschöp, M.H. ; Finan, B. ; DiMarchi, R.D. ; Leinninger, G.M. ; Williams, K.W. ; Clemmensen, C. ; Holst, B.
Long-acting neurotensin synergizes with liraglutide to reverse obesity through a melanocortin-dependent pathway.Jall, S. ; Finan, B. ; Collden, G. ; Fischer, K. ; Dong, X. ; Tschöp, M.H. ; Müller, T.D. ; Clemmensen, C.
Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice.Hellwig, M. ; Lauffer, M.C. ; Bockmayr, M. ; Spohn, M. ; Merk, D.J. ; Harrison, L. ; Ahlfeld, J. ; Kitowski, A. ; Neumann, J.E. ; Ohli, J. ; Holdhof, D. ; Niesen, J. ; Schoof, M. ; Kool, M. ; Kraus, C. ; Zweier, C. ; Holmberg, D. ; Schüller, U.
TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma.Niu, L. ; Geyer, P.E. ; Wewer Albrechtsen, N.J. ; Gluud, L.L. ; Santos, A. ; Doll, S. ; Treit, P.V. ; Holst, J.J. ; Knop, F.K. ; Vilsbøll, T. ; Junker, A. ; Sachs, S. ; Stemmer, K. ; Müller, T.D. ; Tschöp, M.H. ; Hofmann, S.M. ; Mann, M.
Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease.Wettmarshausen, J. ; Perocchi, F.
Assessing calcium-stimulated mitochondrial bioenergetics using the seahorse XF96 analyzer.Quarta, C. ; Fisette, A. ; Xu, Y. ; Collden, G. ; Legutko, B. ; Tseng, Y.-T. ; Reim, A. ; Wierer, M. ; De Rosa, M.C. ; Klaus, V. ; Rausch, R. ; Thaker, V.V. ; Graf, E. ; Strom, T.M. ; Poher, A.-L. ; Gruber, T. ; Le Thuc, O. ; Cebrian Serrano, A. ; Kabra, D.G. ; Bellocchio, L. ; Woods, S.C. ; Pflugfelder, G.O. ; Nogueiras, R. ; Zeltser, L. ; Grunwald Kadow, I.C. ; Moon, A. ; García-Cáceres, C. ; Mann, M. ; Treier, M. ; Doege, C.A. ; Tschöp, M.H.
Functional identity of hypothalamic melanocortin neurons depends on Tbx3.Camargo Ortega, G. ; Falk, S. ; Johansson, P.A. ; Peyre, E. ; Broix, L. ; Sahu, S.K. ; Hirst, W. ; Schlichthaerle, T. ; de Juan Romero, C. ; Draganova, K. ; Vinopal, S. ; Chinnappa, K. ; Gavranovic, A. ; Karakaya, T. ; Steininger, T. ; Merl-Pham, J. ; Feederle, R. ; Shao, W. ; Shi, S.H. ; Hauck, S.M. ; Jungmann, R. ; Bradke, F. ; Borrell, V. ; Geerlof, A. ; Reber, S. ; Tiwari, V.K. ; Huttner, W.B. ; Wilsch-Bräuninger, M. ; Nguyen, L.A. ; Götz, M.
The centrosome protein AKNA regulates neurogenesis via microtubule organization.Plaza-Díaz, J. ; Gómez-Fernández, A. ; Chueca, N. ; Torre-Aguilar, M.J. ; Gil, A. ; Perez-Navero, J.L. ; Flores-Rojas, K. ; Martín-Borreguero, P. ; Solis-Urra, P. ; Ruiz Ojeda, F.J. ; Garcia, F. ; Gil-Campos, M.
Autism Spectrum Disorder (ASD) with and without mental regression is associated with changes in the fecal microbiota.Kleinert, M. ; Bojsen-Møller, K.N. ; Jørgensen, N.B. ; Svane, M.S. ; Martinussen, C. ; Kiens, B. ; Wojtaszewski, J.F.P. ; Madsbad, S. ; Richter, E.A. ; Clemmensen, C.
Effect of bariatric surgery on plasma GDF15 in humans.Papadopoulou, A.A. ; Müller, S.A. ; Mentrup, T. ; Shmueli, M.D. ; Niemeyer, J. ; Haug-Kröper, M. ; von Blume, J. ; Mayerhofer, A. ; Feederle, R. ; Schröder, B. ; Lichtenthaler, S.F. ; Fluhrer, R.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.Sachs, S. ; Zarini, S. ; Kahn, D.E. ; Harrison, K.A. ; Perreault, L. ; Phang, T. ; Newsom, S.A. ; Strauss, A. ; Kerege, A. ; Schoen, J.A. ; Bessesen, D.H. ; Schwarzmayr, T. ; Graf, E. ; Lutter, D. ; Krumsiek, J. ; Hofmann, S.M. ; Bergman, B.C.
Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans.Karlina, R. ; Lutter, D. ; Ussar, S.
Defining murine brown adipose tissue heterogeneityKhajavi, N. ; Finan, B. ; Kluth, O. ; Müller, T.D. ; Mergler, S. ; Schulz, A. ; Kleinau, G. ; Scheerer, P. ; Schuermann, A. ; Gudermann, T. ; Tschöp, M.H. ; Krude, H. ; DiMarchi, R.D. ; Biebermann, H.
Tri-agonist-induced PLC activation is associated with robust insulin secretion from murine islets.Mroz, P.A. ; Finan, B. ; Gelfanov, V. ; Yang, B. ; Tschöp, M.H. ; DiMarchi, R.D. ; Perez-Tilve, D.
Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism.García-Cáceres, C. ; Balland, E. ; Prévot, V. ; Luquet, S. ; Woods, S.C. ; Koch, M. ; Horvath, T.L. ; Yi, C.X. ; Chowen, J.A. ; Verkhratsky, A. ; Araque, A. ; Bechmann, I. ; Tschöp, M.H.
Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism.Keuper, M. ; Berti, L. ; Raedle, B. ; Sachs, S. ; Böhm, A. ; Fritsche, L. ; Fritsche, A. ; Häring, H.-U. ; Hrabě de Angelis, M. ; Jastroch, M. ; Hofmann, S.M. ; Staiger, H.
Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin.Clemmensen, C. ; Finan, B. ; Müller, T.D. ; DiMarchi, R.D. ; Tschöp, M.H. ; Hofmann, S.M.
Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases.Tang, Y. ; Reissig, S. ; Glasmacher, E. ; Regen, T. ; Wanke, F. ; Nikolaev, A. ; Gerlach, K. ; Popp, V. ; Karram, K. ; Fantini, M.C. ; Schattenberg, J.M. ; Galle, P.R. ; Neurath, M.F. ; Weigmann, B. ; Kurschus, F.C. ; Hövelmeyer, N. ; Waisman, A.
Alternative splice forms of CYLD mediate ubiquitination of SMAD7 to prevent TGFB signaling and promote colitis.Görgülü, K. ; Diakopoulos, K.N. ; Ai, J. ; Schoeps, B. ; Kabacaoglu, D. ; Karpathaki, A.F. ; Ciecielski, K.J. ; Kaya-Aksoy, E. ; Ruess, D.A. ; Berninger, A. ; Kowalski, M. ; Stevanovic, M. ; Wörmann, S.M. ; Wartmann, T. ; Zhao, Y. ; Halangk, W. ; Voronina, S. ; Tepikin, A. ; Schlitter, A.M. ; Steiger, K. ; Artati, A. ; Adamski, J. ; Aichler, M. ; Walch, A.K. ; Jastroch, M. ; Hartleben, G. ; Mantzoros, C.S. ; Weichert, W. ; Schmid, R.M. ; Herzig, S. ; Krüger, A. ; Sainz, B. ; Lesina, M. ; Algül, H.
Levels of the autophagy-related 5 protein affect progression and metastasis of pancreatic tumors in mice.Harrison, L. ; Schriever, S.C. ; Feuchtinger, A. ; Kyriakou, E. ; Baumann, P. ; Pfuhlmann, K. ; Messias, A.C. ; Walch, A.K. ; Tschöp, M.H. ; Pfluger, P.T.
Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice.Mueller, K.M. ; Hartmann, K. ; Kaltenecker, D. ; Vettorazzi, S. ; Bauer, M. ; Mauser, L. ; Amann, S. ; Jall, S. ; Fischer, K. ; Esterbauer, H. ; Müller, T.D. ; Tschöp, M.H. ; Magnes, C. ; Haybaeck, J. ; Scherer, T. ; Bordag, N. ; Tuckermann, J.P. ; Moriggl, R.
Erratum. Adipocyte glucocorticoid Receptor deficiency attenuates aging- and HFD-induced obesity and impairs the feeding-fasting transition. Diabetes 2017;66:272-286.Hoffmann, V. ; Lanz, M. ; Mackert, J. ; Müller, T.D. ; Tschöp, M.H. ; Meissner, K.
Effects of placebo interventions on subjective and objective markers of appetite-a randomized controlled trial.Lee, K.Y. ; Luong, Q. ; Sharma, R. ; Dreyfuss, J.M. ; Ussar, S. ; Kahn, C.R.
Developmental and functional heterogeneity of white adipocytes within a single fat depot.Kyriakou, E. ; Schmidt, S. ; Dodd, G.T. ; Pfuhlmann, K. ; Simonds, S.E. ; Lenhart, D. ; Geerlof, A. ; Schriever, S.C. ; de Angelis, M. ; Schramm, K.-W. ; Plettenburg, O. ; Cowley, M.A. ; Tiganis, T. ; Tschöp, M.H. ; Pfluger, P.T. ; Sattler, M. ; Messias, A.C.
Celastrol promotes weight loss in diet-induced obesity by inhibiting the protein tyrosine phosphatases PTP1B and TCPTP in the hypothalamus.di Giaimo, R. ; Durovic, T. ; Barquin, P. ; Kociaj, A. ; Lepko, T. ; Aschenbroich, S. ; Breunig, C. ; Irmler, M. ; Cernilogar, F.M. ; Schotta, G. ; Barbosa, J.S. ; Trümbach, D. ; Baumgart, E.V. ; Neuner, A.M. ; Beckers, J. ; Wurst, W. ; Stricker, S.H. ; Ninkovic, J.
The aryl hydrocarbon receptor pathway defines the time frame for restorative neurogenesis.Clemmensen, C. ; Jall, S. ; Kleinert, M. ; Quarta, C. ; Gruber, T. ; Reber, J. ; Sachs, S. ; Fischer, K. ; Feuchtinger, A. ; Karlas, A. ; Simonds, S.E. ; Grandl, G. ; Loher, D. ; Sanchez-Quant, E. ; Keipert, S. ; Jastroch, M. ; Hofmann, S.M. ; Nascimento, E.B.M. ; Schrauwen, P. ; Ntziachristos, V. ; Cowley, M.A. ; Finan, B. ; Müller, T.D. ; Tschöp, M.H.
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (vol 9, 4304, 2018).Schleger, F. ; Linder, K. ; Walter, L. ; Heni, M. ; Braendle, J. ; Brucker, S. ; Pauluschke-Froehlich, J. ; Weiss, M. ; Häring, H.-U. ; Preissl, H. ; Fritsche, A.
Family history of diabetes is associated with delayed fetal postprandial brain activity.Brandt, S. ; Müller, T.D. ; DiMarchi, R.D. ; Tschöp, M.H. ; Stemmer, K.
Peptide-based multi-agonists: A new paradigm in metabolic pharmacology.Kaplanian, M. ; Hackl, M.T. ; Stemmer, K. ; Luger, A. ; Scherer, T. ; Fuernsinn, C.
Posture of adipose Mice under hypoxia reduces Hyperglycemia without Improving Insulin Sensitivity.Wettmarshausen, J. ; Goh, V. ; Huang, K.T. ; Arduino, D.M. ; Tripathi, U. ; Leimpek, A. ; Cheng, Y. ; Pittis, A.A. ; Gabaldón, T. ; Mokranjac, D. ; Hajnóczky, G. ; Perocchi, F.
MICU1 confers protection from MCU-dependent manganese toxicity.Clemmensen, C. ; Jall, S. ; Kleinert, M. ; Quarta, C. ; Gruber, T. ; Reber, J. ; Sachs, S. ; Fischer, K. ; Feuchtinger, A. ; Karlas, A. ; Simonds, S.E. ; Grandl, G. ; Loher, D. ; Sanchez-Quant, E. ; Keipert, S. ; Jastroch, M. ; Hofmann, S.M. ; Nascimento, E.B.M. ; Schrauwen, P. ; Ntziachristos, V. ; Cowley, M.A. ; Finan, B. ; Müller, T.D. ; Tschöp, M.H.
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.Krahmer, N. ; Najafi, B. ; Schueder, F. ; Quagliarini, F. ; Steger, M. ; Seitz, S. ; Kasper, R. ; Salinas, F. ; Cox, J. ; Uhlenhaut, N.H. ; Walther, T.C. ; Jungmann, R. ; Zeigerer, A. ; Borner, G.H.H. ; Mann, M.
Organellar proteomics and phospho-proteomics reveal subcellular teorganization in diet-induced hepatic steatosis.Capozzi, M.E. ; DiMarchi, R.D. ; Tschöp, M.H. ; Finan, B. ; Campbell, J.E.
Targeting the incretin/glucagon system with triagonists to treat diabetes.Müller, G.
Glycosylphosphatidylinositol-anchored proteins and their release from cells: From phenomenon to meaning.Graja, A. ; Garcia-Carrizo, F. ; Jank, A. ; Gohlke, S. ; Ambrosi, T.H. ; Jonas, W. ; Ussar, S. ; Kern, M.J. ; Schürmann, A. ; Aleksandrova, K. ; Blüher, M. ; Schulz, T.J.
Loss of periostin occurs in aging adipose tissue of mice and its genetic ablation impairs adipose tissue lipid metabolism.Jian, Z. ; Cheng, T. ; Zhang, Z. ; Raulefs, S. ; Shi, K. ; Steiger, K. ; Maeritz, N. ; Kleigrewe, K. ; Hofmann, T. ; Benitz, S. ; Bruns, P. ; Lamp, D. ; Jastroch, M. ; Akkan, J. ; Jäger, C. ; Huang, P.L. ; Nie, S. ; Shen, S.S. ; Zou, X. ; Ceyhan, G.O. ; Michalski, C.W. ; Friess, H. ; Kleeff, J. ; Kong, B.
Glycemic variability promotes both local invasion and metastatic colonization by pancreatic ductal adenocarcinoma.Vogel, H. ; Kamitz, A. ; Hallahan, N. ; Lebek, S. ; Schallschmidt, T. ; Jonas, W. ; Jaehnert, M. ; Gottmann, P. ; Zellner, L. ; Kanzleiter, T. ; Damen, M. ; Altenhofen, D. ; Burkhardt, R. ; Renner, S. ; Dahlhoff, M. ; Wolf, E. ; Müller, T.D. ; Blueher, M. ; Joost, H.G. ; Chadt, A. ; Al-Hasani, H. ; Schuermann, A.
A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes.Dludla, P.V. ; Nkambule, B.B. ; Tiano, L. ; Louw, J. ; Jastroch, M. ; Mazibuko-Mbeje, S.E.
Uncoupling proteins as a therapeutic target to protect the diabetic heart.Li, Z. ; Rasmussen, M.L. ; Li, J. ; Henriquez-Olguin, C. ; Knudsen, J.R. ; Madsen, A.B. ; Sánchez Quant, E.S. ; Kleinert, M. ; Jensen, T.E.
Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements.Pfuhlmann, K. ; Schriever, S.C. ; Baumann, P. ; Kabra, D.G. ; Harrison, L. ; Mazibuko-Mbeje, S. ; Contreras, R.E. ; Kyriakou, E. ; Simonds, S.E. ; Tiganis, T. ; Cowley, M.A. ; Woods, S.C. ; Jastroch, M. ; Clemmensen, C. ; de Angelis, M. ; Schramm, K.-W. ; Sattler, M. ; Messias, A.C. ; Tschöp, M.H. ; Pfluger, P.T.
Celastrol-induced weight loss is driven by hypophagia and independent from UCP1.Holthaus, L. ; Lamp, D. ; Gavrisan, A. ; Sharma, V. ; Ziegler, A.-G. ; Jastroch, M. ; Bonifacio, E.
CD4+ T cell activation, function, and metabolism are inhibited by low concentrations of DMSO.Müller, G.
The release of glycosylphosphatidylinositol-anchored proteins from the cell surface.Müller, T.D. ; Clemmensen, C. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H.
Anti-obesity therapy: From rainbow pills to polyagonists.Suwandhi, L. ; Hausmann, S. ; Braun, A. ; Gruber, T. ; Heinzmann, S.S. ; Gálvez, E.J.C. ; Buck, A. ; Legutko, B. ; Israel, A. ; Feuchtinger, A. ; Haythorne, E. ; Staiger, H. ; Heni, M. ; Häring, H.-U. ; Schmitt-Kopplin, P. ; Walch, A.K. ; Cáceres, C.G. ; Tschöp, M.H. ; Rutter, G.A. ; Strowig, T. ; Elsner, M. ; Ussar, S.
Chronic d-serine supplementation impairs insulin secretion.Jarasch, A. ; Glaser, A. ; Häring, H.-U. ; Roden, M. ; Schürmann, A. ; Solimena, M. ; Theis, F.J. ; Tschöp, M.H. ; Wess, G. ; Hrabě de Angelis, M.
Mit Big Data zur personalisierten Diabetesprävention.Quiñones, M. ; Al-Massadi, O. ; Folgueira, C. ; Bremser, S. ; Gallego, R. ; Torres-Leal, L. ; Haddad-Tóvolli, R. ; García-Cáceres, C. ; Hernandez-Bautista, R. ; Lam, B.Y.H. ; Beiroa, D. ; Sanchez-Rebordelo, E. ; Senra, A. ; Malagon, J.A. ; Valerio, P. ; Fondevila, M.F. ; Fernø, J. ; Malagon, M.M. ; Contreras, R. ; Pfluger, P.T. ; Brüning, J.C. ; Yeo, G. ; Tschöp, M.H. ; Diéguez, C. ; López, M. ; Claret, M. ; Kloppenburg, P. ; Sabio, G. ; Nogueiras, R.
p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.Dyar, K.A. ; Lutter, D. ; Artati, A. ; Ceglia, N.J. ; Liu, Y. ; Armenta, D. ; Jastroch, M. ; Schneider, S. ; de Mateo, S. ; Cervantes, M. ; Abbondante, S. ; Tognini, P. ; Orozco-Solis, R. ; Kinouchi, K. ; Wang, C. ; Swerdloff, R. ; Nadeef, S. ; Masri, S. ; Magistretti, P. ; Orlando, V. ; Borrelli, E. ; Uhlenhaut, N.H. ; Baldi, P. ; Adamski, J. ; Tschöp, M.H. ; Eckel-Mahan, K.L. ; Sassone-Corsi, P.
Atlas of circadian metabolism reveals system-wide coordination and communication between clocks.Dyar, K.A. ; Huber, M.J. ; Mir, A.A. ; Ciciliot, S. ; Lutter, D. ; Greulich, F. ; Quagliarini, F. ; Kleinert, M. ; Fischer, K. ; Eichmann, T.O. ; Wright, L.E. ; Peña Paz, M.I. ; Casarin, A. ; Pertegato, V. ; Romanello, V. ; Albiero, M. ; Mazzucco, S. ; Rizzuto, R. ; Salviati, L. ; Biolo, G. ; Blaauw, B. ; Schiaffino, S. ; Uhlenhaut, N.H.
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.International Wheat Genome Sequencing Consortium (Eversole, K. ; Feuillet, C. ; Keller, B. ; Rogers, J. ; Stein, N. ; Appels, R.) ; Pozniak, C.J. ; Choulet, F. ; Distelfeld, A. ; Poland, J. ; Ronen, G ; Sharpe, A.G. ; Pozniak, C. ; Barad, O. ; Baruch, K. ; Choulet, F. ; Keeble-Gagnère, G. ; Mascher, M. ; Ben-Zvi, G. ; Josselin, A.A. ; Himmelbach, A. ; Balfourier, F. ; Gutierrez-Gonzalez, J. ; Hayden, M. ; Josselin, A.A. ; Koh, C. ; Muehlbauer, G. ; Pasam, R.K. ; Paux, E. ; Rigault, P. ; Tibbits, J. ; Tiwari, V. ; Choulet, F. ; Spannagl, M. ; Lang, D. ; Gundlach, H. ; Haberer, G. ; Mayer, K.F.X. ; Ormanbekova, D. ; Paux, E. ; Prade, V.M. ; Šimková, H. ; Wicker, T. ; Swarbreck, D. ; Rimbert, H. ; Guilhot, N. ; Kaithakottil, G. ; Keilwagen, J. ; Leroy, P. ; Lux, T. ; Twardziok, S.O. ; Venturini, L. ; Juhász, A ; Abrouk, M ; Fischer, I.P. ; Uauy, C. ; Borrill, P ; Ramirez-Gonzalez, R.H. ; Arnaud, D. ; Chalabi, S. ; Chalhoub, B. ; Cory, A. ; Datla, R. ; Davey, M.W. ; Hayden, M. ; Jacobs, J. ; Robinson, S.J. ; Steuernagel, B. ; Tibbits, J. ; Tiwari, V. ; van Ex, F. ; Wulff, B.B.H. ; Robinson, S.J. ; Cory, A. ; Benhamed, M. ; Paux, E. ; Bendahmane, A. ; Concia, L. ; Latrasse, D. ; Rogers, J. ; Alaux, M. ; Bartoš, J. ; Bellec, A. ; Berges, H. ; Doležel, J. ; Frenkel, Z ; Gill, B. ; Korol, A. ; Letellier, T. ; Olsen, O.A. ; Singh, K. ; Valárik, M. ; van der Vossen, E. ; Vautrin, S. ; Weining, S. ; Korol, A. ; Frenkel, Z. ; Fahima, T. ; Glikson, V. ; Raats, D. ; Tiwari, V. ; Gill, B. ; Paux, E. ; Číhalíková, J. ; Toegelová, H. ; Vrána, J. ; Sourdille, P. ; Darrier, B. ; Barabaschi, D. ; Cattivelli, L ; Hernandez, P. ; Galvez, S. ; Budak, H. ; Jones, J.D.G. ; Witek, K. ; Yu, G. ; Small, I. ; Melonek, J. ; Zhou, R. ; Juhász, A. ; Belova, T. ; Kanyuka, K. ; King, R. ; Nilsen, K. ; Walkowiak, S. ; Cuthbert, R. ; Datla, R. ; Knox, R. ; Wiebe, K. ; Xiang, D. ; Rohde, A. ; Golds, T. ; Čížková, J. ; Akpinar, B.A. ; Biyiklioglu, S. ; Muehlbauer, G. ; Gao, L. ; Gutierrez-Gonzalez, J. ; N'Daiye, A. ; Číhalíková, J. ; Kubaláková, M. ; Šafář, J. ; Berges, H. ; Bellec, A. ; Vautrin, S. ; Alaux, M. ; Alfama, F. ; Adam-Blondon, A.F. ; Flores, R. ; Guerche, C. ; Letellier, T. ; Loaec, M. ; Quesneville, H. ; Condie, J. ; Ens, J. ; Koh, C. ; Maclachlan, R. ; Tan, Y. ; Paux, E. ; Alberti, A. ; Aury, J.M. ; Barbe, V. ; Couloux, A. ; Cruaud, C. ; Labadie, K. ; Mangenot, S. ; Wincker, P. ; Gill, B. ; Kaur, G. ; Luo, M. ; Sehgal, S. ; Chhuneja, P. ; Gupta, O.P. ; Jindal, S. ; Kaur, P. ; Malik, P. ; Sharma, P. ; Yadav, B. ; Singh, N.K. ; Khurana, J. ; Chaudhary, C. ; Khurana, P. ; Kumar, V. ; Mahato, A. ; Mathur, S. ; Sevanthi, A. ; Sharma, N. ; Tomar, R.S. ; Jacobs, J. ; Alaux, M. ; Bellec, A. ; Berges, H. ; Frenkel, Z. ; Gill, B. ; Korol, A. ; van der Vossen, E. ; Vautrin, S. ; Kaur, G. ; Luo, M. ; Sehgal, S. ; Bartoš, J. ; Holušová, K. ; Plíhal, O. ; Clark, M.D. ; Heavens, D. ; Kettleborough, G. ; Wright, J. ; Valárik, M. ; Abrouk, M. ; Balcárková, B. ; Holušová, K. ; Hu, Y. ; Luo, M. ; Salina, E. ; Ravin, N. ; Skryabin, K. ; Beletsky, A. ; Kadnikov, V. ; Mardanov, A. ; Nesterov, M. ; Rakitin, A. ; Sergeeva, E. ; Handa, H. ; Kanamori, H. ; Katagiri, S. ; Kobayashi, F. ; Nasuda, S. ; Tanaka, T. ; Wu, J. ; Hayden, M. ; Rigault, P. ; Cattonaro, F. ; Jiumeng, M. ; Kugler, K.G. ; Pfeifer, M. ; Sandve, S. ; Xun, X. ; Zhan, B. ; Abrouk, M. ; Batley, J. ; Bayer, P.E. ; Edwards, D. ; Hayashi, S. ; Tulpová, Z. ; Visendi, P. ; Weining, S. ; Cui, L. ; Du, X. ; Feng, K. ; Nie, X. ; Tong, W.G. ; Wang, L. ; Galvez, S. ; Lux, T. ; Ramirez-Gonzalez, R.H. ; Venturini, L. ; Hernandez, P ; Kanyuka, K ; Paux, E.
Shifting the limits in wheat research and breeding using a fully annotated reference genome.Khajavi, N. ; Finan, B. ; Kluth, O. ; Müller, T.D. ; Mergler, S. ; Schulz, A. ; Kleinau, G. ; Scheerer, P. ; Schürmann, A. ; Gudermann, T. ; Tschöp, M.H. ; Krude, H. ; DiMarchi, R.D. ; Biebermann, H.
An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation.Nikolakopoulou, P. ; Chatzigeorgiou, A. ; Kourtzelis, I. ; Toutouna, L. ; Masjkur, J. ; Arps-Forker, C. ; Poser, S.W. ; Rozman, J. ; Rathkolb, B. ; Aguilar-Pimentel, J.A. ; German Mouse Clinic Consortium ; Wolf, E. ; Klingenspor, M. ; Ollert, M. ; Schmidt-Weber, C.B. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Tsata, V. ; Sebastian Monasor, L. ; Troullinaki, M. ; Witt, A. ; Anastasiou, V. ; Chrousos, G. ; Yi, C.-X. ; García-Cáceres, C. ; Tschöp, M.H. ; Bornstein, S.R. ; Androutsellis-Theotokis, A. ; German Mouse Clinic Consortium (Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Amarie, O.V. ; Graw, J. ; Neff, F.)
Streptozotocin-induced beta-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.Polymeropoulos, E.T. ; Oelkrug, R. ; Jastroch, M.
Editorial: The evolution of endothermy-from patterns to mechanisms.Kleinert, M. ; Parker, B.L. ; Jensen, T.E. ; Raun, S.H. ; Pham, P. ; Han, X. ; James, D.E. ; Richter, E.A. ; Sylow, L.
Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training.Al-Massadi, O. ; Müller, T.D. ; Tschöp, M.H. ; Diéguez, C. ; Nogueiras, R.
Ghrelin and LEAP-2: Rivals in energy metabolism.Treberg, J.R. ; Munro, D. ; Jastroch, M. ; Quijada-Rodriguez, A.R. ; Kutschke, M. ; Wiens, L.
Comparing electron leak in vertebrate muscle mitochondria.Götz, A. ; Lehti, M. ; Donelan, E. ; Striese, C. ; Cucuruz, S. ; Sachs, S. ; Yi, C.X. ; Woods, S.C. ; Wright, S.D. ; Tschöp, M.H. ; Gao, Y. ; Hofmann, S.M.
Circulating HDL levels control hypothalamic astrogliosis via apoA-I.Müller, D. ; Telieps, T. ; Eugster, A. ; Weinzierl, C. ; Jolink, M. ; Ziegler, A.-G. ; Bonifacio, E.
Novel minor HLA DR associated antigens in type 1 diabetes.Giuranna, J. ; Volckmar, A.L. ; Heinen, A. ; Peters, T. ; Schmidt, B. ; Spieker, A. ; Straub, H. ; Grallert, H. ; Müller, T.D. ; Antel, J. ; Haussmann, U. ; Klafki, H. ; Liangyou, R. ; Hebebrand, J. ; Hinney, A.
The effect of SH2B1 variants on expression of leptin- and insulin-induced pathways in murine hypothalamus.Simon, J.J. ; Becker, A. ; Sinno, M.H. ; Skunde, M. ; Bendszus, M. ; Preissl, H. ; Enck, P. ; Herzog, W. ; Friederich, H.
Neural food reward processing in successful and unsuccessful weight maintenance.Renner, S. ; Blutke, A. ; Dobenecker, B. ; Dhom, G. ; Müller, T.D. ; Finan, B. ; Clemmensen, C. ; Bernau, M. ; Novak, I. ; Rathkolb, B. ; Senf, S. ; Zöls, S. ; Roth, M. ; Götz, A. ; Hofmann, S.M. ; Hrabě de Angelis, M. ; Wanke, R. ; Kienzle, E. ; Scholz, A.M. ; DiMarchi, R. ; Ritzmann, M. ; Tschöp, M.H. ; Wolf, E.
Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs.Kim, T. ; Nason, S. ; Holleman, C. ; Pepin, M. ; Wilson, L.C. ; Berryhill, T.F. ; Wende, A.R. ; Steele, C. ; Young, M.E. ; Barnes, S. ; Drucker, D.J. ; Finan, B. ; DiMarchi, R. ; Perez-Tilve, D. ; Tschöp, M.H. ; Habegger, K.M.
Glucagon receptor signaling regulates energy metabolism via hepatic farnesoid X receptor and fibroblast growth factor 21.Cheng, Y. ; Jiang, L. ; Keipert, S. ; Zhang, S. ; Hauser, A. ; Graf, E. ; Strom, T.M. ; Tschöp, M.H. ; Jastroch, M. ; Perocchi, F.
Prediction of adipose browning capacity by systematic integration of transcriptional profiles.Sustarsic, E.G. ; Ma, T. ; Lynes, M.D. ; Larsen, M. ; Karavaeva, I. ; Havelund, J.F. ; Nielsen, C.H. ; Jedrychowski, M.P. ; Moreno-Torres, M. ; Lundh, M. ; Plucinska, K. ; Jespersen, N.Z. ; Grevengoed, T.J. ; Kramar, B. ; Peics, J. ; Hansen, J.B. ; Shamsi, F. ; Forss, I. ; Neess, D. ; Keipert, S. ; Wang, J. ; Stohlmann, K. ; Brandslund, I. ; Christensen, C. ; Jørgensen, M.E. ; Linneberg, A. ; Pedersen, O. ; Kiebish, M.A. ; Qvortrup, K. ; Han, X. ; Pedersen, B.K. ; Jastroch, M. ; Mandrup, S. ; Kjær, A. ; Gygi, S.P. ; Hansen, T. ; Gillum, M.P. ; Grarup, N. ; Emanuelli, B. ; Nielsen, S. ; Scheele, C. ; Tseng, Y.H. ; Færgeman, N.J. ; Gerhart-Hines, Z.
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis.Brandt, S. ; Kleinert, M. ; Tschöp, M.H. ; Müller, T.D.
Are peptide conjugates the golden therapy against obesity?Kleinert, M. ; Kotzbeck, P. ; Altendorfer-Kroath, T. ; Birngruber, T. ; Tschöp, M.H. ; Clemmensen, C.
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood-brain barrier in leptin resistant mice.Wei, Y. ; Corbalán-Campos, J. ; Gurung, R. ; Natarelli, L. ; Zhu, M. ; Exner, N. ; Erhard, F. ; Greulich, F. ; Geißler, C. ; Uhlenhaut, N.H. ; Zimmer, R. ; Schober, A.
Dicer in macrophages prevents atherosclerosis by promoting mitochondrial oxidative metabolism.Arduino, D.M. ; Perocchi, F.
Pharmacological modulation of mitochondrial calcium homeostasis.Davari, K. ; Lichti, J. ; Friedel, C.C. ; Glasmacher, E.
Real-time analysis of Ttanscription factor binding, transcription, translation, and turnover to display global events during cellular activation.Schöttl, T. ; Fischer, I.P. ; Ussar, S.
Heterogeneity of adipose tissue in development and metabolic function.Huang, J. ; Duran, A. ; Reina-Campos, M. ; Valencia, T. ; Castilla, E.A. ; Müller, T.D. ; Tschöp, M.H. ; Moscat, J. ; Diaz-Meco, M.T.
Adipocyte p62/SQSTM1 suppresses tumorigenesis through opposite regulations of metabolism in adipose tissue and tumor.Fujisaka, S. ; Avila-Pacheco, J. ; Soto, M. ; Kostic, A. ; Dreyfuss, J.M. ; Pan, H. ; Ussar, S. ; Altindis, E. ; Li, N. ; Bry, L. ; Clish, C.B. ; Kahn, C.R.
Diet, genetics, and the gut microbiome drive dynamic changes in plasma metabolites.Jastroch, M. ; Oelkrug, R. ; Keipert, S.
Insights into brown adipose tissue evolution and function from non-model organisms.Brandt, S. ; Mayer, J.P. ; Ford, J. ; Gelfanov, V.M. ; DiMarchi, R.D.
Controlled intramolecular antagonism as a regulator of insulin receptor maximal activity.Kleinert, M. ; Clemmensen, C. ; Sjøberg, K.A. ; Carl, C.S. ; Jeppesen, J.F. ; Wojtaszewski, J.F.P. ; Kiens, B. ; Richter, E.A.
Exercise increases circulating GDF15 in humans.Draganova, R. ; Schollbach, A. ; Schleger, F. ; Braendle, J. ; Brucker, S. ; Abele, H. ; Kagan, K.O. ; Wallwiener, D. ; Fritsche, A. ; Eswaran, H. ; Preissl, H.
Fetal auditory evoked responses to onset of amplitude modulated sounds. A fetal magnetoencephalography (fMEG) study.Schiaffino, S. ; Dyar, K.A. ; Calabria, E.
Skeletal muscle mass is controlled by the MRF4-MEF2 axis.Chrétien, D. ; Bénit, P. ; Ha, H.H. ; Keipert, S. ; El-Khoury, R. ; Chang, Y.T. ; Jastroch, M. ; Jacobs, H.T. ; Rustin, P. ; Rak, M.
Mitochondria are physiologically maintained at close to 50 °C.DiMarchi, R.D. ; Mayer, J.P. ; Gelfanov, V.M. ; Tschöp, M.H.
Max Bergmann award lecture: Macromolecular medicinal chemistry as applied to metabolic diseases.Poher, A.-L. ; Tschöp, M.H. ; Müller, T.D.
Ghrelin regulation of glucose metabolism.Pfuhlmann, K. ; Schriever, S.C. ; Legutko, B. ; Baumann, P. ; Harrison, L. ; Kabra, D.G. ; Baumgart, E.V. ; Tschöp, M.H. ; García-Cáceres, C. ; Pfluger, P.T.
Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice.Brandt, S. ; Götz, A. ; Tschöp, M.H. ; Müller, T.D.
Gut hormone polyagonists for the treatment of type 2 diabetes.Spetter, M.S. ; Feld, G.B. ; Thienel, M. ; Preissl, H. ; Hege, M.A. ; Hallschmid, M.
Oxytocin curbs calorie intake via food-specific increases in the activity of brain areas that process reward and establish cognitive control.Verkhratsky, A. ; Trebak, M. ; Perocchi, F. ; Khananshvili, D. ; Sekler, I.
Crosslink between calcium and sodium signalling.Rozman, J. ; Rathkolb, B. ; Oestereicher, M.A. ; Schütt, C. ; Ravindranath, A.C. ; Leuchtenberger, S. ; Sharma, S. ; Kistler, M. ; Willershäuser, M. ; Brommage, R. ; Meehan, T.F. ; Mason, J. ; Haselimashhadi, H. ; Hough, T. ; Mallon, A.-M. ; Wells, S. ; Santos, L. ; Lelliott, C.J. ; White, J.K. ; Sorg, T. ; Champy, M.-F. ; Bower, L.R. ; Reynolds, C.L. ; Flenniken, A.M. ; Murray, S.A. ; Nutter, L.M.J. ; Svenson, K.L. ; West, D. ; Tocchini-Valentini, G.P. ; Beaudet, A.L. ; Bosch, F. ; Braun, R.B. ; Dobbie, M.S. ; Gao, X. ; Herault, Y. ; Moshiri, A. ; Moore, B.A. ; Kent Lloyd, K.C. ; McKerlie, C. ; Masuya, H. ; Tanaka, N. ; Flicek, P. ; Parkinson, H.E. ; Sedlacek, R. ; Seong, J.K. ; Wang, C.-K.L. ; Moore, M. ; Brown, S.D. ; Tschöp, M.H. ; Wurst, W. ; Klingenspor, M. ; Wolf, E. ; Beckers, J. ; Machicao, F. ; Peter, A. ; Staiger, H. ; Häring, H.-U. ; Grallert, H. ; Campillos, M. ; Maier, H. ; Fuchs, H. ; Gailus-Durner, V. ; Werner, T. ; Hrabě de Angelis, M. ; IMPC Consortium (Eickelberg, O.) ; IMPC Consortium (Yildirim, A.Ö.)
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.Walheim, E. ; Wiśniewski, J.R. ; Jastroch, M.
Respiromics - An integrative analysis linking mitochondrial bioenergetics to molecular signatures.Lee, I. ; Preissl, H. ; Giel, K.E. ; Schag, K. ; Enck, P.
Attentional and physiological processing of food images in functional dyspepsia patients: A pilot study.Kleinert, M. ; Clemmensen, C. ; Hofmann, S.M. ; Moore, M.C. ; Renner, S. ; Woods, S.C. ; Huypens, P. ; Beckers, J. ; Hrabě de Angelis, M. ; Schürmann, A. ; Bakhti, M. ; Klingenspor, M. ; Heimann, M. ; Cherrington, A.D. ; Ristow, M. ; Lickert, H. ; Wolf, E. ; Havel, P.J. ; Müller, T.D. ; Tschöp, M.H.
Animal models of obesity and diabetes mellitus.Grandl, G. ; Wolfrum, C.
Hemostasis, endothelial stress, inflammation, and the metabolic syndrome.Rahn, S. ; Zimmermann, V. ; Viol, F. ; Stemmer, K. ; Peters, L. ; Lenk, L. ; Ungefroren, H. ; Saur, D. ; Schäfer, H. ; Helm, O. ; Sebens, S.
Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Buday, K. ; Roveri, A. ; Peng, X. ; Porto Freitas, F. ; Seibt, T. ; Mehr, L. ; Aichler, M. ; Walch, A.K. ; Lamp, D. ; Jastroch, M. ; Miyamoto, S. ; Wurst, W. ; Ursini, F. ; Arnér, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis.Kindt, A. ; Fuerst, R.W. ; Knoop, J. ; Laimighofer, M. ; Telieps, T. ; Hippich, M. ; Woerheide, M.A. ; Wahl, S. ; Wilson, R. ; Sedlmeier, E.-M. ; Hommel, A. ; Todd, J.A. ; Krumsiek, J. ; Ziegler, A.-G. ; Bonifacio, E.
Allele-specific methylation of type 1 diabetes susceptibility genes.Lichti, J. ; Gallus, C. ; Glasmacher, E.
Immune responses - Transcriptional and post-transcriptional networks pass the baton.Nagler, J. ; Schriever, S.C. ; de Angelis, M. ; Pfluger, P.T. ; Schramm, K.-W.
Comprehensive analysis of nine monoamines and metabolites in small amounts of peripheral murine (C57Bl/6J) tissues.Ryan, K.K. ; Packard, A.E.B. ; Larson, K.R. ; Stout, J. ; Fourman, S.M. ; Thompson, A.M.K. ; Ludwick, K. ; Habegger, K.M. ; Stemmer, K. ; Itoh, N. ; Perez-Tilve, D. ; Tschöp, M.H. ; Seeley, R.J. ; Ulrich-Lai, Y.M.
Dietary manipulations that induce ketosis activate the HPA axis in male rats and mice: A potential role for fibroblast growth factor-21.Einer, C. ; Hohenester, S. ; Wimmer, R. ; Wottke, L. ; Artmann, R. ; Schulz, S. ; Gosmann, C. ; Simmons, A. ; Leitzinger, C. ; Eberhagen, C. ; Borchard, S. ; Schmitt, S. ; Hauck, S.M. ; von Toerne, C. ; Jastroch, M. ; Walheim, E. ; Rust, C. ; Gerbes, A.L. ; Popper, B. ; Mayr, D. ; Schnurr, M. ; Vollmar, A.M. ; Denk, G.U. ; Zischka, H.
Mitochondrial adaptation in steatotic mice.Fischer, I.P. ; Irmler, M. ; Meyer, C.W.E. ; Sachs, S. ; Neff, F. ; Hrabě de Angelis, M. ; Beckers, J. ; Tschöp, M.H. ; Hofmann, S.M. ; Ussar, S.
A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue.Le Thuc, O. ; Noël, J. ; Rovère, C.
An ex vivo perifusion method for quantitative determination of neuropeptide release from mouse hypothalamic explants.Zhang, C.J. ; Bidlingmaier, M. ; Altaye, M. ; Page, L.C. ; D'Alessio, D. ; Tschöp, M.H. ; Tong, J.
Acute administration of acyl, but not desacyl ghrelin, decreases blood pressure in healthy humans.Kabra, U.D.
The role of mitochondrial fission protein Drp1 in pancreatic islets and beta cells.Müller, G.
Gesundheit – Vom (bio)technologischen, (eigen)verantwortlichen, fairen und realistischen Umgang.Walheim, E.
Energy deprivation induces a specific secretome in skeletal muscle.Kurz, S. ; Janas, M.K. ; Schneider, A. ; Lohr, K. ; Wettmarshausen, J. ; Perocchi, F. ; Knolle, P.A. ; Wohlleber, D.
Linking TNF receptor signaling in virus-infected hepatocytes to cell death for immune control of liver infection.Einer, C. ; Hohenester, S. ; Wimmer, R. ; Wottke, L. ; Artmann, R. ; Schulz, S. ; Gosmann, C. ; Simmons, A. ; Leitzinger, C. ; Eberhagen, C. ; Borchard, S. ; Schmitt, S. ; Hauck, S.M. ; von Toerne, C. ; Jastroch, M. ; Walheim, E. ; Rust, C. ; Gerbes, A.L. ; Popper, B. ; Mayr, D. ; Schnurr, M. ; Vollmar, A.M. ; Denk, G. ; Zischka, H.
Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks.Holze, C. ; Michaudel, C. ; Mackowiak, C. ; Haas, D.A. ; Benda, C. ; Hubel, P. ; Pennemann, F.L. ; Schnepf, D. ; Wettmarshausen, J. ; Braun, M. ; Leung, D.W. ; Amarasinghe, G.K. ; Perocchi, F. ; Staeheli, P. ; Ryffel, B. ; Pichlmair, A.
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Roveri, A. ; Peng, X. ; Freitas, F.P. ; Aichler, M. ; Jastroch, M. ; Ursini, F. ; Arner, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 was an evolutionary requirement to prevent hydroperoxide-induced ferroptosis.Tom, R.Z. ; Gao, Y. ; Schriever, S.C. ; Lutter, D. ; Yi, C.-X. ; Tschöp, M.H. ; Hofmann, S.M.
Role of neuronal fractalkine in reducing diet-induced hypothalamic inflammation.Knerr, P.J. ; Finan, B. ; Gelfanov, V. ; Perez-Tilve, D. ; Tschöp, M.H. ; DiMarchi, R.D.
Optimization of peptide-based polyagonists for treatment of diabetes and obesity.Balsevich, G. ; Häusl, A.S. ; Meyer, C.W. ; Karamihalev, S. ; Feng, X. ; Pöhlmann, M.L. ; Dournes, C. ; Uribe-Marino, A. ; Santarelli, S. ; Labermaier, C. ; Hafner, K. ; Mao, T. ; Breitsamer, M. ; Theodoropoulou, M. ; Namendorf, C. ; Uhr, M. ; Paez-Pereda, M. ; Winter, G. ; Hausch, F. ; Chen, A. ; Tschöp, M.H. ; Rein, T. ; Gassen, N.C. ; Schmidt, M.V.
Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.Polymeropoulos, E.T. ; Oelkrug, R. ; Jastroch, M.
Mitochondrial proton leak compensates for reduced oxidative power during frequent hypothermic events in a protoendothermic mammal, Echinops telfairi.Warncke, K. ; Lickert, R. ; Eitel, S. ; Gloning, K.P. ; Bonifacio, E. ; Sedlmeier, E.-M. ; Becker, P. ; Knoop, J. ; Beyerlein, A. ; Ziegler, A.-G.
Thymus growth and fetal immune responses in diabetic pregnancies.Lefort, S. ; Tschöp, M.H. ; García-Cáceres, C.
A synaptic basis for GLP-1 action in the brain.De Azua, I.R. ; Mancini, G.M. ; Srivastava, R.K. ; Rey, A.A. ; Cardinal, P. ; Tedesco, L. ; Zingaretti, C.M. ; Sassmann, A. ; Quarta, C. ; Schwitter, C. ; Conrad, A. ; Wettschureck, N. ; Vemuri, V.K. ; Makriyannis, A. ; Hartwig, J.H. ; Mendez-Lago, M. ; Bindila, L. ; Monory, K. ; Giordano, A. ; Cinti, S. ; Marsicano, G. ; Offermanns, S. ; Nisoli, E. ; Pagotto, U. ; Cota, D. ; Lutz, B.
Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.Piotrowski, C. ; Lede, V. ; Butthof, A. ; Kaiser, N. ; Hirrlinger, P.G. ; Tschöp, M.H. ; Schöneberg, T. ; Bechmann, I.
Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb.Lee, K.Y. ; Sharma, R. ; Gase, G. ; Ussar, S. ; Li, Y. ; Welch, L. ; Berryman, D.E. ; Kispert, A. ; Blüher, M. ; Kahn, C.R.
Tbx15 defines a glycolytic subpopulation and white adipocyte heterogeneity.Götz, A. ; Jall, S. ; Tschöp, M.H. ; Müller, T.D.
Inkretinbasierte Medikamente zur Diabetes- und Adipositastherapie. Entwicklungsperspektiven.Gaudry, M.J. ; Jastroch, M. ; Treberg, J.R. ; Hofreiter, M. ; Paijmans, J.L.A. ; Starrett, J. ; Wales, N. ; Signore, A.V. ; Springer, M.S. ; Campbell, K.L.
Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades.Duncan, L. ; Yilmaz, Z. ; Gaspar, H. ; Walters, R. ; Goldstein, J.I. ; Anttila, V. ; Bulik-Sullivan, B. ; Ripke, S. ; Thornton, L.M. ; Hinney, A. ; Daly, M. ; Sullivan, P.F. ; Zeggini, E. ; Breen, G. ; Bulik, C.M. ; Eating Disorders Working Group of the Psychiatric Genomics Consortium (Wichmann, H.-E. ; Tschöp, M.H.)
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa.Ravichandran, M. ; Grandl, G. ; Ristow, M.
Dietary carbohydrates impair healthspan and promote mortality.Gao, Y. ; Vidal-Itriago, A. ; Kalsbeek, M.J. ; Layritz, C. ; García-Cáceres, C. ; Tom, R.Z. ; Eichmann, T.O. ; Vaz, F.M. ; Houtkooper, R.H. ; van der Wel, N. ; Verhoeven, A.J. ; Yan, J. ; Kalsbeek, A. ; Eckel, R.H. ; Hofmann, S.M. ; Yi, C.X.
Lipoprotein lipase maintains microglial innate immunity in obesity.Kleinert, M. ; Clemmensen, C. ; Stemmer, K. ; Müller, T.D. ; DiMarchi, R.D. ; Tschöp, M.H.
Emerging poly-agonists for obesity and type 2 diabetes.Wiens, L. ; Banh, S. ; Sotiri, E. ; Jastroch, M. ; Block, B.A. ; Brand, M.D. ; Treberg, J.R.
Comparison of mitochondrial reactive oxygen species production of ectothermic and endothermic fish muscle.Quarta, C. ; Clemmensen, C. ; Zhu, Z. ; Yang, B. ; Joseph, S.S. ; Lutter, D. ; Yi, C.X. ; Graf, E. ; García-Cáceres, C. ; Legutko, B. ; Fischer, K. ; Brommage, R. ; Zizzari, P. ; Franklin, B.S. ; Krueger, M. ; Koch, M. ; Vettorazzi, S. ; Li, P. ; Hofmann, S.M. ; Bakhti, M. ; Bastidas-Ponce, A. ; Lickert, H. ; Strom, T.M. ; Gailus-Durner, V. ; Bechmann, I. ; Perez-Tilve, D. ; Tuckermann, J.P. ; Hrabě de Angelis, M. ; Sandoval, D.A. ; Cota, D. ; Latz, E. ; Seeley, R.J. ; Müller, T.D. ; DiMarchi, R.D. ; Finan, B. ; Tschöp, M.H.
Molecular integration of incretin and glucocorticoid action reverses immunometabolic dysfunction and obesity.Pfuhlmann, K. ; Pfluger, P.T. ; Schriever, S.C. ; Müller, T.D. ; Tschöp, M.H. ; Stemmer, K.
Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice.Wang, X. ; Haering, M.-F. ; Rathjen, T. ; Lockhart, S.M. ; Sorensen, D. ; Ussar, S. ; Rasmussen, L.M. ; Bertagnolli, M.M. ; Kahn, C.R. ; Rask-Madsen, C.
Insulin resistance in vascular endothelial cells promotes intestinal tumour formation.Kälin, S. ; Becker, M. ; Ott, V. ; Serr, I. ; Hosp, F. ; Mollah, M.M.H. ; Keipert, S. ; Lamp, D. ; Rohner-Jeanrenaud, F. ; Flynn, V.K. ; Scherm, M.G. ; Nascimento, L.F.R. ; Gerlach, K. ; Popp, V. ; Dietzen, S. ; Bopp, T. ; Krishnamurthy, P. ; Kaplan, M.H. ; Serrano, M. ; Woods, S.C. ; Tripal, P. ; Palmisano, R. ; Jastroch, M. ; Blüher, M. ; Wolfrum, C. ; Weigmann, B. ; Ziegler, A.-G. ; Mann, M. ; Tschöp, M.H. ; Daniel, C.
A Stat6/Pten axis links regulatory T cells with adipose tissue function.Böttcher, A. ; Lickert, H. ; Tschöp, M.H.
Engineering skin with skinny genes.Mayer, J.P. ; Tschöp, M.H. ; DiMarchi, R.D.
Once blind, now we see GLP-1 molecular action.Arduino, D.M. ; Wettmarshausen, J. ; Vais, H. ; Navas-Navarro, P. ; Cheng, Y. ; Leimpek, A. ; Ma, Z. ; Delrio-Lorenzo, A. ; Giordano, A. ; Garcia-Perez, C. ; Médard, G. ; Kuster, B. ; García-Sancho, J. ; Mokranjac, D. ; Foskett, J.K. ; Alonso, M.T. ; Perocchi, F.
Systematic identification of MCU modulators by orthogonal Iiterspecies chemical screening.Khajavi, N. ; Biebermann, H. ; Tschöp, M.H. ; DiMarchi, R.
Treatment of diabetes and obesity by rationally designed peptide agonists functioning at multiple metabolic receptors.Pramme-Steinwachs, I. ; Jastroch, M. ; Ussar, S.
Extracellular calcium modulates brown adipocyte differentiation and identity.Frias, J.P. ; Bastyr, E.J. ; Vignati, L. ; Tschöp, M.H. ; Schmitt, C. ; Owen, K.R. ; Christensen, R.H. ; DiMarchi, R.D.
The sustained effects of a dual GIP/GLP-1 receptor agonist, NNC0090-2746, in patients with type 2 diabetes.Le Thuc, O. ; Stobbe, K. ; Cansell, C. ; Nahon, J.L. ; Blondeau, N. ; Rovère, C.
Hypothalamic inflammation and energy balance disruptions: Spotlight on chemokines.Keipert, S. ; Kutschke, M. ; Ost, M. ; Schwarzmayr, T. ; van Schothorst, E.M. ; Lamp, D. ; Brachthäuser, L. ; Hamp, I. ; Mazibuko-Mbeje, S. ; Hartwig, S. ; Lerch, S. ; Graf, E. ; Plettenburg, O. ; Neff, F. ; Tschöp, M.H. ; Jastroch, M.
Long-term cold adaptation does not require FGF21 or UCP1.Sánchez-Garrido, M.A. ; Brandt, S. ; Clemmensen, C. ; Müller, T.D. ; DiMarchi, R.D. ; Tschöp, M.H.
GLP-1/glucagon receptor co-agonism for treatment of obesity.Jastroch, M.
Uncoupling protein 1 controls reactive oxygen species in brown adipose tissue.Fritsche, A. ; Heni, M. ; Gancheva, S. ; Preissl, H. ; Kullmann, S. ; Lehnert, H. ; Tschöp, M.H. ; Brüning, J.C. ; Roden, M. ; Häring, H.-U.
Das Gehirn als Schaltzentrale des Stoffwechsels.Gao, Y. ; Layritz, C. ; Legutko, B. ; Eichmann, T.O. ; Laperrousaz, E. ; Moullé, V.S. ; Cruciani-Guglielmacci, C. ; Magnan, C. ; Luquet, S. ; Woods, S.C. ; Eckel, R.H. ; Yi, C.-X. ; Garcia-Caceres, C. ; Tschöp, M.H.
Disruption of lipid uptake in astroglia exacerbates diet induced obesity.Hankir, M.K. ; Kranz, M. ; Keipert, S. ; Weiner, J. ; Andreasen, S.G. ; Kern, M.J. ; Patt, M. ; Kloeting, N. ; Heiker, J.T. ; Brust, P. ; Hesse, S. ; Jastroch, M. ; Fenske, W.K.
Dissociation between brown adipose tissue 18F-FDG uptake and thermogenesis in uncoupling protein 1 deficient mice.Keuper, M. ; Sachs, S. ; Walheim, E. ; Berti, L. ; Raedle, B. ; Tews, D. ; Fischer-Posovszky, P. ; Wabitsch, M. ; Hrabě de Angelis, M. ; Kastenmüller, G. ; Tschöp, M.H. ; Jastroch, M. ; Staiger, H. ; Hofmann, S.M.
Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors.Rathjen, T. ; Yan, X. ; Kononenko, N.L. ; Ku, M.C. ; Song, K. ; Ferrarese, L. ; Tarallo, V. ; Puchkov, D. ; Kochlamazashvili, G. ; Brachs, S. ; Varela, L. ; Szigeti-Buck, K. ; Yi, C.-X. ; Schriever, S.C. ; Tattikota, S.G. ; Carlo, A.S. ; Moroni, M. ; Siemens, J. ; Heuser, A. ; van der Weyden, L. ; Birkenfeld, A.L. ; Niendorf, T. ; Poulet, J.F.A. ; Horvath, T.L. ; Tschöp, M.H. ; Heinig, M. ; Trajkovski, M. ; Haucke, V. ; Poy, M.N.
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.Giles, D.A. ; Moreno-Fernandez, M.E. ; Stankiewicz, T.E. ; Graspeuntner, S. ; Cappelletti, M. ; Wu, D. ; Mukherjee, R. ; Chan, C.C. ; Lawson, M.J. ; Klarquist, J. ; Sünderhauf, A. ; Softic, S. ; Kahn, C.R. ; Stemmer, K. ; Iwakura, Y. ; Aronow, B.J. ; Karns, R. ; Steinbrecher, K.A. ; Karp, C.L. ; Sheridan, R. ; Shanmukhappa, S.K. ; Reynaud, D. ; Haslam, D.B. ; Sina, C. ; Rupp, J. ; Hogan, S.P. ; Divanovic, S.
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.Tschöp, M.H. ; DiMarchi, R.
Single-molecule combinatorial therapeutics for treating obesity and diabetes.Tkatch, T. ; Greotti, E. ; Baranauskas, G. ; Pendin, D. ; Roy, S. ; Nita, L.I. ; Wettmarshausen, J. ; Prigge, M. ; Yizhar, O. ; Shirihai, O.S. ; Fishman, D. ; Hershfinkel, M. ; Fleidervish, I.A. ; Perocchi, F. ; Pozzan, T. ; Sekler, I.
Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins.Gao, Y. ; Bielohuby, M. ; Fleming, T. ; Grabner, G.F. ; Foppen, E. ; Bernhard, W. ; Guzmán-Ruiz, M. ; Layritz, C. ; Legutko, B. ; Zinser, E. ; García-Cáceres, C. ; Buijs, R.M. ; Woods, S.C. ; Kalsbeek, A. ; Seeley, R.J. ; Nawroth, P.P. ; Bidlingmaier, M. ; Tschöp, M.H. ; Yi, C.X.
Dietary sugars, not lipids, drive hypothalamic inflammation.Gruber, T. ; Garcia-Caceres, C. ; Le Thuc, O. ; Legutko, B. ; Horvath, T.L. ; Tschöp, M.H.
Hypercaloric environment triggers chronic remodeling of the hypothalamic vasculature via astroglial HIF1 alpha and VEGF signaling.Legutko, B. ; Gruber, T. ; Caceres, C.G. ; Le Thuc, O. ; Horvath, T. ; Tschöp, M.H.
Astrocytic leptin and insulin signals interact to maintain systemic metabolic homeostasis.Le Thuc, O. ; Legutko, B. ; Gruber, T. ; Li, D. ; Luquet, S. ; Tschöp, M.H. ; Garcia-Caceres, C.
Hypothalamic astrocyte activity state determines systemic glucose metabolism in mice.Caceres, C.G. ; Le Thuc, O. ; Legutko, B. ; Gruber, T. ; Jastroch, M. ; Varela, L. ; Diano, S. ; Horvath, T. ; Tschöp, M.H.
Astrocytic UCP2 is required for hypothalamic response to metabolic challenges.Dirscherl, P. ; Jastroch, M. ; Vogt-Weisenhorn, D. ; Wurst, W.
Mitochondrial function in Pink1 deficient astrocytes.Schaub, A. ; Glasmacher, E.
Splicing in immune cells - mechanistic insights and emerging topics.Kleinert, M. ; Parker, B.L. ; Fritzen, A.M. ; Knudsen, J.R. ; Jensen, T.E. ; Kjøbsted, R. ; Sylow, L. ; Ruegg, M.A. ; James, D.E. ; Richter, E.A.
Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice.Reißig, S. ; Tang, Y. ; Nikolaev, A. ; Gerlach, K. ; Wolf, C. ; Davari, K. ; Gallus, C. ; Masri, J. ; Mufazalov, I.A. ; Neurath, M.F. ; Wunderlich, F.T. ; Schattenberg, J.M. ; Galle, P.R. ; Weigmann, B. ; Waisman, A. ; Glasmacher, E. ; Hövelmeyer, N.
Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis.Davari, K. ; Lichti, J. ; Gallus, C. ; Greulich, F. ; Uhlenhaut, N.H. ; Heinig, M. ; Friedel, C.C. ; Glasmacher, E.
Rapid genome-wide recruitment of RNA polymerase II drives transcription, splicing, and translation events during T cell responses.Collden, G. ; Tschöp, M.H. ; Müller, T.D.
Therapeutic potential of targeting the ghrelin pathway.Nathan, S.R. ; Pino, N.W. ; Arduino, D.M. ; Perocchi, F. ; MacMillan, S.N. ; Wilson, J.J.N.
Synthetic methods for the preparation of a functional analogue of Ru360, a potent inhibitor of mitochondrial calcium uptake.Ussar, S. ; Haering, M.-F. ; Fujisaka, S. ; Lutter, D. ; Lee, K.Y. ; Li, N. ; Gerber, G.K. ; Bry, L. ; Kahn, C.R.
Regulation of glucose uptake and enteroendocrine function by the intestinal epithelial insulin receptor.Schriever, S.C. ; Zimprich, A. ; Pfuhlmann, K. ; Baumann, P. ; Giesert, F. ; Klaus, V. ; Kabra, D. ; Hafen, U. ; Romanov, A. ; Tschöp, M.H. ; Wurst, W. ; Conrad, M. ; Hölter, S.M. ; Weisenhorn, D.M. ; Pfluger, P.T.
Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.Klaus, V. ; Bastek, H. ; Damme, K. ; Collins, L.B. ; Frötschl, R. ; Benda, N. ; Lutter, D. ; Ellinger-Ziegelbauer, H. ; Swenberg, J.A. ; Dietrich, D.R. ; Stemmer, K.
Time-matched analysis of DNA adduct formationand early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats.Varela, L. ; Suyama, S. ; Huang, Y. ; Shanabrough, M. ; Tschöp, M.H. ; Gao, X.B. ; Giodano, F.J. ; Horvath, T.L.
Endothelial HIF-1α enables hypothalamic glucose uptake to drive POMC neurons.Aichler, M. ; Borgmann, D.M. ; Krumsiek, J. ; Buck, A. ; MacDonald, P.E. ; Fox, J.E.M. ; Lyon, J. ; Light, P.E. ; Keipert, S. ; Jastroch, M. ; Feuchtinger, A. ; Müller, N.S. ; Sun, N. ; Palmer, A. ; Alexandrov, T. ; Hrabě de Angelis, M. ; Neschen, S. ; Tschöp, M.H. ; Walch, A.K.
N-acyl taurines and acylcarnitines cause an imbalance in insulin synthesis and secretion provoking β cell dysfunction in type 2 diabetes.Fuchs, Y.F. ; Eugster, A. ; Dietz, S. ; Sebelefsky, C. ; Kühn, D. ; Wilhelm, C. ; Lindner, A. ; Gavrisan, A. ; Knoop, J. ; Dahl, A. ; Ziegler, A.-G. ; Bonifacio, E.
CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.Le Thuc, O. ; Rovère, C.
[Hypothalamic inflammation and energy balance deregulations: Focus on chemokines.].Laperrousaz, E. ; Moullé, V.S. ; Denis, R.G. ; Kassis, N. ; Berland, C. ; Colsch, B. ; Fioramonti, X. ; Philippe, E. ; Lacombe, A. ; Vanacker, C. ; Butin, N. ; Bruce, K.D. ; Wang, H. ; Wang, Y. ; Gao, Y. ; García-Cáceres, C. ; Prévot, V. ; Tschöp, M.H. ; Eckel, R.H. ; Le Stunff, H. ; Luquet, S. ; Magnan, C. ; Cruciani-Guglielmacci, C.
Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.Müller, T.D. ; Finan, B. ; Clemmensen, C. ; DiMarchi, R.D. ; Tschöp, M.H.
The new biology and pharmacology of glucagon.Honrath, B. ; Matschke, L. ; Meyer, T. ; Magerhans, L. ; Perocchi, F. ; Ganjam, G.K. ; Zischka, H. ; Krasel, C. ; Gerding, A. ; Bakker, B.M. ; Bünemann, M. ; Strack, S. ; Decher, N. ; Culmsee, C. ; Dolga, A.M.
SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.Wettmarshausen, J. ; Perocchi, F.
Isolation of functional mitochondria from cultured cells and mouse tissues.Kabra, U.D. ; Pfuhlmann, K. ; Migliorini, A. ; Keipert, S. ; Lamp, D. ; Korsgren, O. ; Gegg, M. ; Woods, S.C. ; Pfluger, P.T. ; Lickert, H. ; Affourtit, C. ; Tschöp, M.H. ; Jastroch, M.
Direct substrate delivery into mitochondrial-fission deficient pancreatic islets rescues insulin secretion.Jastroch, M. ; Tschöp, M.H.
METABOLISM. Fat controls U. Circulating uridine acts as a hunger signal.Sylow, L. ; Kleinert, M. ; Richter, E.A. ; Jensen, T.E.
Exercise-stimulated glucose uptake - regulation and implications for glycaemic control.Kahn, C.R. ; Ussar, S.
Response to comment on Ussar et al. Regulation of glucose uptake and enteroendocrine function by the intestinal epithelial insulin receptor. Diabetes 2017;66:886-896.Yi, C.-X. ; Walter, M.C. ; Gao, Y. ; Pitra, S. ; Legutko, B. ; Kälin, S. ; Layritz, C. ; García-Cáceres, C. ; Bielohuby, M. ; Bidlingmaier, M. ; Woods, S.C. ; Ghanem, A. ; Conzelmann, K.K. ; Stern, J.E. ; Jastroch, M. ; Tschöp, M.H.
TNFα drives mitochondrial stress in POMC neurons in obesity.Clemmensen, C. ; Müller, T.D. ; Woods, S.C. ; Berthoud, H.R. ; Seeley, R.J. ; Tschöp, M.H.
Gut-brain cross-talk in metabolic control.Jall, S. ; Sachs, S. ; Clemmensen, C. ; Finan, B. ; Neff, F. ; DiMarchi, R.D. ; Tschöp, M.H. ; Müller, T.D. ; Hofmann, S.M.
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice.Hinney, A. ; Kesselmeier, M. ; Jall, S. ; Volckmar, A.L. ; Föcker, M. ; Antel, J. ; Heid, I.M. ; Winkler, T.W. ; Grant, S.F.A. ; Guo, Y. ; Bergen, A.W. ; Kaye, W. ; Berrettini, W. ; Hakonarson, H. ; Herpertz-Dahlmann, B. ; de Zwaan, M. ; Herzog, W. ; Ehrlich, S. ; Zipfel, S. ; Egberts, K.M. ; Adan, R.A. ; Brandys, M.K. ; van Elburg, A.A. ; Perica, V.B. ; Franklin, C.S. ; Tschop, M.H. ; Zeggini, E. ; Bulik, C.M. ; Collier, D.A. ; Scherag, A. ; Müller, T.D. ; Hebebrand, J.
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index (vol 22, pg 192, 2017).Fischer, K. ; Ruiz, H.H. ; Jhun, K. ; Finan, B. ; Oberlin, D.J. ; van der Heide, V. ; Kalinovich, A.V. ; Petrovic, N. ; Wolf, Y. ; Clemmensen, C. ; Shin, A.C. ; Divanovic, S. ; Brombacher, F. ; Glasmacher, E. ; Keipert, S. ; Jastroch, M. ; Nagler, J. ; Schramm, K.-W. ; Medrikova, D. ; Collden, G. ; Woods, S.C. ; Herzig, S. ; Homann, D. ; Jung, S. ; Nedergaard, J. ; Cannon, B. ; Tschöp, M.H. ; Müller, T.D. ; Buettner, C.
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis.Polymeropoulos, E.T. ; Oelkrug, R. ; White, C.R. ; Jastroch, M.
Phylogenetic analysis of the allometry of metabolic rate and mitochondrial basal proton leak.Al Massadi, O. ; López, M. ; Tschöp, M.H. ; Dieguez, C. ; Nogueiras, R.
Current understanding of the hypothalamic ghrelin pathways inducing appetite and adiposity.Heninger, A.K. ; Jergens, S. ; Wilhelm, C. ; Beyerlein, A. ; Ziegler, A.-G. ; Bonifacio, E.
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity.Clemmensen, C. ; Jørgensen, C.V. ; Smajilovic, S. ; Bräuner-Osborne, H.
Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor.Ost, M. ; Keipert, S. ; Klaus, S.
Targeted mitochondrial uncoupling beyond UCP1 - The fine line between death and metabolic health.Hinney, A. ; Kesselmeier, M. ; Jall, S. ; Volckmar, A.L. ; Föcker, M. ; Antel, J. ; Genetic Consortium for Anorexia Nervosa (GCAN) () ; Wellcome Trust Case Control Consortium 3 (WTCCC3) () ; Heid, I.M. ; Winkler, T.W. ; GIANT Consortium (Collier, D.A. ; Gieger, C. ; Müller, T.D. ; Illig, T. ; Scherag, A. ; Hebebrand, J. ; Thorand, B. ; Wichmann, H.-E.) ; Grant, S.F. ; Early Growth Genetics Consortium () ; Guo, Y. ; Bergen, A.W. ; Kaye, W. ; Berrettini, W. ; Hakonarson, H. ; Price Foundation Collaborative Group () ; Children's Hospital of Philadelphia/Price Foundation () ; Herpertz-Dahlmann, B. ; de Zwaan, M. ; Herzog, W. ; Ehrlich, S. ; Zipfel, S. ; Egberts, K.M. ; Adan, R.A. ; Brandys, M.K. ; van Elburg, A.A. ; Boraska Perica, V. ; Franklin, C.S. ; Tschöp, M.H.
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index.Gerencser, A.A. ; Mookerjee, S.A. ; Jastroch, M. ; Brand, M.D.
Positive feedback amplifies the response of mitochondrial membrane potential to glucose concentration in clonal pancreatic beta cells.Huypens, P. ; Sass, S. ; Wu, M. ; Dyckhoff, D. ; Tschöp, M.H. ; Theis, F.J. ; Marschall, S. ; Hrabě de Angelis, M. ; Beckers, J.
Epigenetic germline inheritance of diet-induced obesity and insulin resistance.Bernhardt, K. ; Haar, J. ; Tsai, M.H. ; Poirey, R. ; Feederle, R. ; Delecluse, H.-J.
A viral microRNA cluster regulates the expression of PTEN, p27 and of a bcl-2 homolog.Fujisaka, S. ; Ussar, S. ; Clish, C.B. ; Devkota, S. ; Dreyfuss, J.M. ; Sakaguchi, M. ; Soto, M. ; Konsishi, M. ; Softic, S. ; Altindis, E. ; Li, N. ; Gerber, G. ; Bry, L. ; Kahn, R.
Antibiotic effects on gut microbiota and metabolism are host dependent.Schlehe, J.S. ; Ussar, S.
Das Mikrobiom: Einfluss auf Adipositas und Diabetes.Jack, B.U. ; Malherbe, C.J. ; Huisamen, B. ; Gabuza, K. ; Mazibuko-Mbeje, S. ; Schulze, A.E. ; Joubert, E. ; Muller, C.J.F. ; Louw, J. ; Pheiffer, C.
A polyphenol-enriched fraction of Cyclopia intermedia decreases lipid content in 3T3-L1 adipocytes and reduces body weight gain of obese db/db mice.Sánchez-Garrido, M.A. ; Habegger, K.M. ; Clemmensen, C. ; Holleman, C. ; Müller, T.D. ; Perez-Tilve, D. ; Li, P. ; Agrawal, A.S. ; Finan, B. ; Drucker, D.J. ; Tschöp, M.H. ; DiMarchi, R.D. ; Kharitonenkov, A.
Fibroblast activation protein (FAP) as a novel metabolic target.Gerencser, A.A. ; Mookerjee, S.A. ; Jastroch, M. ; Brand, M.D.
Measurement of the absolute magnitude and time courses of mitochondrial membrane potential in primary and clonal pancreatic beta-cells.Müller, V. ; Remus, K. ; Hoffmann, V. ; Tschöp, M.H. ; Meissner, K.
Effectiveness of a placebo intervention on visually induced nausea in women – A randomized controlled pilot study.Pigoni, M. ; Wanngren, J. ; Kuhn, P.-H. ; Munro, K.M. ; Gunnersen, J.M. ; Takeshima, H. ; Feederle, R. ; Voytyuk, I. ; de Strooper, B. ; Levasseur, M.D. ; Hrupka, B.J. ; Mueller, S.A. ; Lichtenthaler, S.F.
Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.Serr, I. ; Fürst, R.W. ; Ott, V.B. ; Scherm, M.G. ; Nikolaev, A. ; Gökmen, F. ; Kälin, S. ; Zillmer, S. ; Bunk, M. ; Weigmann, B. ; Kunschke, N. ; Loretz, B. ; Lehr, C.M. ; Kirchner, B. ; Haase, B. ; Pfaffl, M.W. ; Waisman, A. ; Willis, R.A. ; Ziegler, A.G. ; Daniel, C.
miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.Jastroch, M. ; Giroud, S. ; Barrett, P. ; Geiser, F. ; Heldmaier, G. ; Herwig, A.
Seasonal control of mammalian energy balance: Recent advances in the understanding of daily torpor and hibernation.Groß, C. ; Mishra, R. ; Schneider, K. ; Médard, G. ; Wettmarshausen, J. ; Dittlein, D. ; Shih, H. ; Gorka, O. ; König, P. ; Fromm, S. ; Magnani, G. ; Cikovic, T. ; Hartjes, L. ; Smollich, J. ; Robertson, A.A.B. ; Cooper, M.A. ; Schmidt-Supprian, M. ; Schuster, M. ; Schroder, K. ; Broz, P. ; Traidl-Hoffmann, C. ; Beutler, B. ; Kuster, B. ; Ruland, J. ; Schneider, S. ; Perocchi, F. ; Groß, O.
K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria.Feederle, R. ; Gerber, J.K. ; Middleton, A. ; Northrup, E. ; Kist, R. ; Kremmer, E. ; Peters, H.
Generation of Pax1/PAX1-specific monoclonal antibodies.Albanese, M. ; Tagawa, T. ; Bouvet, M. ; Maliqi, L. ; Lutter, D. ; Hoser, J.D.S. ; Hastreiter, M. ; Hayes, M. ; Sugden, B. ; Martin, L. ; Moosmann, A. ; Hammerschmidt, W.
Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.Enriori, P.J. ; Chen, W. ; Garcia-Rudaz, M.C. ; Grayson, B.E. ; Evans, A.E. ; Comstock, S.M. ; Gebhardt, U. ; Müller, H.L. ; Reinehr, T. ; Henry, B.A. ; Brown, R.D. Jr. ; Bruce, C.R. ; Simonds, S.E. ; Litwak, S.A. ; McGee, S.L. ; Luquet, S. ; Martinez, S. ; Jastroch, M. ; Tschöp, M.H. ; Watt, M.J. ; Clarke, I.J. ; Roth, C.L. ; Grove, K.L. ; Cowley, M.A.
α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors.Xiang, X. ; Werner, G. ; Bohrmann, B. ; Mazaheri, F. ; Capell, A. ; Feederle, R. ; Knuesel, I. ; Kleinberger, G. ; Haass, C.
TREM2-deficiency reduces the efficacy of immunotherapeutic amyloid clearance.Finan, B. ; Clemmensen, C. ; Zhu, Z. ; Stemmer, K. ; Gauthier, K. ; Müller, L. ; de Angelis, M. ; Moreth, K. ; Neff, F. ; Perez-Tilve, D. ; Fischer, K. ; Lutter, D. ; Sánchez-Garrido, M.A. ; Liu, P. ; Tuckermann, J.P. ; Malehmir, M. ; Healy, M.E. ; Weber, A. ; Heikenwälder, M. ; Jastroch, M. ; Kleinert, M. ; Jall, S. ; Brandt, S. ; Flamant, F. ; Schramm, K.-W. ; Biebermann, H. ; Döring, Y. ; Weber, C. ; Habegger, K.M. ; Keuper, M. ; Gelfanov, V. ; Liu, F. ; Köhrle, J. ; Rozman, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Hofmann, S.M. ; Yang, B. ; Tschöp, M.H. ; DiMarchi, R. ; Müller, T.D.
Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic Impact for metabolic disease.Mueller, K.M. ; Hartmann, K. ; Kaltenecker, D. ; Vettorazzi, S. ; Bauer, M. ; Mauser, L. ; Amann, S. ; Jall, S. ; Fischer, K. ; Esterbauer, H. ; Müller, T.D. ; Tschöp, M.H. ; Magnes, C. ; Haybaeck, J. ; Scherer, T. ; Bordag, N. ; Tuckermann, J.P. ; Moriggl, R.
Adipocyte glucocorticoid receptor deficiency attenuates aging and HFDinduced obesity, and impairs the feedingfasting transition.de Angelis, M. ; Giesert, F. ; Finan, B. ; Clemmensen, C. ; Müller, T.D. ; Vogt Weisenhorn, D.M. ; Tschöp, M.H. ; Schramm, K.-W.
Determination of thyroid hormones in mouse tissues by isotope-dilution microflow liquid chromatography-mass spectrometry method.Müller, G.
Zivilisationskrankheiten – Für eine gesamtwissenschaftliche Prädiktion und Prävention. Molekulare, phänomenologische, systemische und gestalttheoretische Analyse von Altersdiabetes.Tagawa, T. ; Albanese, M. ; Bouvet, M. ; Moosmann, A. ; Mautner, J. ; Heissmeyer, V. ; Zielinski, C. ; Lutter, D. ; Hoser, J.D.S. ; Hastreiter, M. ; Hayes, M. ; Sugden, B. ; Hammerschmidt, W.
Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing.Ussar, S. ; Fujisaka, S. ; Kahn, C.R.
Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome.Reissig, S. ; Nikolaev, A. ; Weigmann, B. ; Gerlach, K. ; Glasmacher, E. ; Hoevelmeyer, N. ; Waisman, A.
The transcriptional regulator Bcl-3 impaires the function of regulatory T cells leading to the development of intestinal inflammation.Maida, A. ; Zota, A. ; Sjøberg, K.A. ; Schumacher, J. ; Sijmonsma, T.P. ; Pfenninger, A. ; Christensen, M.M. ; Gantert, T. ; Fuhrmeister, J. ; Rothermel, U. ; Schmoll, D. ; Heikenwälder, M. ; Iovanna, J.L. ; Stemmer, K. ; Kiens, B. ; Herzig, S. ; Rose, A.J.
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.Hernandez-Garzón, E. ; Fernandez, A.M. ; Perez-Alvarez, A. ; Genis, L. ; Bascuñana, P. ; de la Rosa, R.F. ; Delgado, M. ; Pozo, M.A. ; Moreno, E. ; McCormick, P.J. ; Santi, A. ; Trueba-Saiz, A. ; García-Cáceres, C. ; Tschöp, M.H. ; Araque, A. ; Martin, E.D. ; Torres Aleman, I.
The insulin-like growth factor I receptor regulates glucose transport by astrocytes.García-Cáceres, C. ; Quarta, C. ; Varela, L. ; Gao, Y. ; Gruber, T. ; Legutko, B. ; Jastroch, M. ; Johansson, P.A. ; Ninkovic, J. ; Yi, C.-X. ; Le Thuc, O. ; Szigeti-Buck, K. ; Cai, W. ; Meyer, C.W. ; Pfluger, P.T. ; Fernandez, A.M. ; Luquet, S. ; Woods, S.C. ; Torres-Alemán, I. ; Kahn, C.R. ; Götz, M. ; Horvath, T.L. ; Tschöp, M.H.
Astrocytic insulin signaling couples brain glucose uptake with nutrient availability.Kleinwort, K.J. ; Amann, B. ; Hauck, S.M. ; Feederle, R. ; Sekundo, W. ; Deeg, C.A.
Immunological characterization of intraocular lymphoid follicles in a spontaneous recurrent uveitis model.Haack, T.B. ; Ignatius, E. ; Calvo-Garrido, J. ; Iuso, A. ; Isohanni, P. ; Maffezzini, C. ; Lönnqvist, T. ; Suomalainen, A. ; Gorza, M. ; Kremer, L.S. ; Graf, E. ; Hartig, M. ; Berutti, R. ; Paucar, M. ; Svenningsson, P. ; Stranneheim, H. ; Brandberg, G. ; Wedell, A. ; Kurian, M.A. ; Hayflick, S.A. ; Venco, P. ; Tiranti, V. ; Strom, T.M. ; Dichgans, M. ; Horvath, R. ; Holinski-Feder, E. ; Freyer, C. ; Meitinger, T. ; Prokisch, H. ; Senderek, J. ; Wredenberg, A. ; Carroll, C.J. ; Klopstock, T.
Absence of the autophagy adaptor SQSTM1/p62 causes childhood-onset neurodegeneration with ataxia, dystonia, and gaze palsy.Ziegler, A.-G. ; Haupt, F. ; Scholz, M. ; Weininger, K. ; Wittich, S. ; Löbner, S. ; Matzke, C. ; Gezginci, C. ; Riethausen, S. ; Beyerlein, A. ; Zillmer, S. ; Amoroso, M. ; Coles, R. ; Powell, M. ; Furmaniak, J. ; Rees Smith, B. ; Winkler, C. ; Bonifacio, E. ; Achenbach, P.
3 screen ELISA for high-throughput detection of beta cell autoantibodies in capillary blood.Müller, A. ; Niederstadt, L. ; Jonas, W. ; Yi, C.X. ; Meyer, F. ; Wiedmer, P. ; Fischer, J. ; Grötzinger, C. ; Schürmann, A. ; Tschöp, M.H. ; Kleinau, G. ; Grüters, A. ; Krude, H. ; Biebermann, H.
Ring finger protein 11 inhibits melanocortin 3 and 4 receptor signaling.Vogel, H. ; Wolf, S. ; Rabasa, C. ; Rodriguez-Pacheco, F. ; Babaei, C.S. ; Stöber, F. ; Goldschmidt, J. ; DiMarchi, R.D. ; Finan, B. ; Tschöp, M.H. ; Dickson, S.L. ; Schürmann, A. ; Skibicka, K.P.
GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight.Kleinert, M. ; Parker, B.L. ; Chaudhuri, R. ; Fazakerley, D.J. ; Serup, A. ; Thomas, K.C. ; Krycer, J.R. ; Sylow, L. ; Fritzen, A.M. ; Hoffman, N.J. ; Jeppesen, J. ; Schjerling, P. ; Ruegg, M.A. ; Kiens, B. ; James, D.E. ; Richter, E.A.
MTORC2 and AMPK differentially regulate muscle triglyceride content via perilipin 3.Müller, T.D. ; Tschöp, M.H. ; O'Rahilly, S.
Metabolic precision medicines: Curing POMC deficiency.Gerencser, A.A. ; Mookerjee, S.A. ; Jastroch, M. ; Brand, M.D.
Measurement of the absolute magnitude and time courses of mitochondrial membrane potential in primary and clonal pancreatic beta-cells.Fuente-Martin, E. ; García-Cáceres, C. ; Argente-Arizon, P. ; Díaz, F. ; Granado, M. ; Freire-Regatillo, A. ; Castro-Gonzalez, D. ; Ceballos, M.L. ; Frago, L.M. ; Dickson, S.L. ; Argente, J. ; Chowen, J.A.
Ghrelin regulates glucose and glutamate transporters in hypothalamic astrocytes.Bader, E. ; Migliorini, A. ; Gegg, M. ; Moruzzi, N. ; Gerdes, J.M. ; Roscioni, S. ; Bakhti, M. ; Brandl, E. ; Irmler, M. ; Beckers, J. ; Aichler, M. ; Feuchtinger, A. ; Leitzinger, C. ; Zischka, H. ; Wang-Sattler, R. ; Jastroch, M. ; Tschöp, M.H. ; Machicao, F. ; Staiger, H. ; Häring, H.-U. ; Chmelova, H. ; Chouinard, J.A. ; Oskolkov, N. ; Korsgren, O. ; Speier, S. ; Lickert, H.
Identification of proliferative and mature β-cells in the islets of Langerhans.Kunath, N. ; Müller, N.C. ; Tonon, M. ; Konrad, B.N. ; Pawlowski, M. ; Kopczak, A. ; Elbau, I. ; Uhr, M. ; Kühn, S. ; Repantis, D. ; Ohla, K. ; Müller, T.D. ; Fernández, G. ; Tschöp, M.H. ; Czisch, M. ; Steiger, A. ; Dresler, M.
Ghrelin modulates encoding-related brain function without enhancing memory formation in humans.Endesfelder, D. ; Hagen, M. ; Winkler, C. ; Haupt, F. ; Zillmer, S. ; Knopff, A. ; Bonifacio, E. ; Ziegler, A.-G. ; zu Castell, W. ; Achenbach, P.
A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children.Xiang, X. ; Werner, G. ; Bohrmann, B. ; Liesz, A. ; Mazaheri, F. ; Capell, A. ; Feederle, R. ; Knuesel, I. ; Kleinberger, G. ; Haass, C.
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.Tschöp, M.H. ; Finan, B. ; Clemmensen, C. ; Gelfanov, V. ; Perez-Tilve, D. ; Müller, T.D. ; DiMarchi, R.D.
Unimolecular polypharmacy for treatment of diabetes and obesity.Scherm, M.G. ; Ott, V. ; Daniel, C.
Follicular helper T cells in autoimmunity.Tschöp, M.H. ; Stumvoll, M. ; Ristow, M.
Opposing effects of antidiabetic interventions on malignant growth and metastasis.Hytönen, J. ; Leppaenen, O. ; Braesen, J.H. ; Schunck, W.H. ; Müller, D. ; Jung, F. ; Mrowietz, C. ; Jastroch, M. ; von Bergwelt-Baildon, M. ; Kappert, K. ; Heuser, A. ; Drenckhahn, J.D. ; Pieske, B. ; Thierfelder, L. ; Yla-Herttuala, S. ; Blaschke, F.
Activation of peroxisome proliferator-activated receptor-δ as novel therapeutic strategy to prevent in-stent restenosis and stent thrombosis.Quarta, C. ; Clemmensen, C.
Unforeseen role for glucocorticoids in combinatorial anti-obesity pharmacology.Walther, D. ; Eugster, A. ; Jergens, S. ; Gavrisan, A. ; Weinzierl, C. ; Telieps, T. ; Winkler, C. ; Ziegler, A.-G. ; Bonifacio, E.
Tetraspanin 7 autoantibodies in type 1 diabetes.Raab, J. ; Haupt, F. ; Scholz, M. ; Matzke, C. ; Warncke, K. ; Lange, K. ; Assfalg, R. ; Weininger, K. ; Wittich, S. ; Löbner, S. ; Beyerlein, A. ; Nennstiel-Ratzel, U. ; Lang, M. ; Laub, O. ; Dunstheimer, D. ; Bonifacio, E. ; Achenbach, P. ; Winkler, C. ; Ziegler, A.-G.
Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: Design and initial results of the Fr1da study.Jouffe, C. ; Gobet, C. ; Martin, E. ; Métairon, S. ; Morin-Rivron, D. ; Masoodi, M. ; Gachon, F.
Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism.Gomes, I. ; Bobeck, E.N. ; Margolis, E.B. ; Gupta, A. ; Sierra, S. ; Fakira, A.K. ; Fujita, W. ; Müller, T.D. ; Müller, A. ; Tschöp, M.H. ; Kleinau, G. ; Fricker, L.D. ; Devi, L.A.
Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.Berland, C. ; Cansell, C. ; Hnasko, T.S. ; Magnan, C. ; Luquet, S.
Dietary triglycerides as signaling molecules that influence reward and motivation.Hausmann, S. ; Ussar, S.
Insulin receptor trafficking steers insulin action.Finan, B. ; Müller, T.D. ; Clemmensen, C. ; Perez-Tilve, D. ; Tschöp, M.H.
Reappraisal of GIP pharmacology for metabolic diseases.Tine, M. ; Kuhl, H. ; Teske, P.R. ; Tschöp, M.H. ; Jastroch, M.
Diversification and coevolution of the ghrelin/growth hormone secretagogue receptor system in vertebrates.Quarta, C. ; Sánchez-Garrido, M.A. ; Tschöp, M.H. ; Clemmensen, C.
Renaissance of leptin for obesity therapy.Huypens, P. ; Sass, S. ; Wu, M. ; Dyckhoff, D. ; Tschöp, M.H. ; Theis, F.J. ; Marschall, S. ; Hrabě de Angelis, M. ; Beckers, J.
Epigenetic germline inheritance of diet-induced obesity and insulin resistance.Kabra, D.G. ; Pfuhlmann, K. ; García-Cáceres, C. ; Schriever, S.C. ; Casquero García, V. ; Kebede, A.F. ; Fuente-Martin, E. ; Trivedi, C. ; Heppner, K. ; Uhlenhaut, N.H. ; Legutko, B. ; Kabra, U.D. ; Gao, Y. ; Yi, C.-X. ; Quarta, C. ; Clemmensen, C. ; Finan, B. ; Müller, T.D. ; Meyer, C.W. ; Paez-Pereda, M. ; Stemmer, K. ; Woods, S.C. ; Perez-Tilve, D. ; Schneider, R. ; Olson, E.N. ; Tschöp, M.H. ; Pfluger, P.T.
Hypothalamic leptin action is mediated by histone deacetylase 5.García-Cáceres, C. ; Tschöp, M.H.
Hypothalamic injury: Fish oil to the rescue!Jung, B. ; Padula, D. ; Burtscher, I. ; Landerer, C. ; Lutter, D. ; Theis, F.J. ; Messias, A.C. ; Geerlof, A. ; Sattler, M. ; Kremmer, E. ; Boldt, K. ; Ueffing, M. ; Lickert, H.
Pitchfork and Gprasp2 target smoothened to the primary cilium for Hedgehog pathway activation.Müller, G.
Assays for insulin and insulin-like metabolic activity based on hepatocytes, myocytes and diaphragms.Müller, G.
Measurement of insulin and other glucose-regulating peptide hormones.Müller, G.
Monitoring of diabetic late complication.Müller, G.
Personalized diagnosis and therapy.Müller, G.
Assays for insulin and Insulin-like regulation of energy metabolism.Müller, G.
Insulin analogs: Assessment of insulin mitogenicity and IGF-I activity.Müller, G.
Insulin target tissues and cells.Müller, G.
Assays for insulin and insulin-like activity based on adipocytes.Müller, G.
Measurement of blood glucose-lowering and antidiabetic activity.Müller, G.
Assays for insulin and insulin-like regulation of gene and protein expression.Müller, G.
Measurement of glucose absorption.Müller, G.
Methods to induce experimental Diabetes Mellitus.Müller, G.
Genetically diabetic animals.Müller, G.
Assays for insulin and insulin-like signal transduction based on adipocytes, hepatocytes and myocytes.Müller, G.
Assays for the expression and release of insulin and glucose-regulating peptide hormones from pancreatic β-cell.Bernhardt, K. ; Haar, J. ; Tsai, M.H. ; Poirey, R. ; Feederle, R. ; Delecluse, H.J.
A viral microRNA cluster regulates the expression of PTEN, p27 and of a bcl-2 homolog.Raab, S. ; Wang, H. ; Uhles, S. ; Cole, N. ; Alvarez-Sanchez, R. ; Künnecke, B. ; Ullmer, C. ; Matile, H. ; Bedoucha, M. ; Norcross, R.D. ; Ottaway-Parker, N. ; Perez-Tilve, D. ; Conde Knape, K. ; Tschöp, M.H. ; Hoener, M.C. ; Sewing, S.
Incretin-like effects of small molecule trace amine-associated receptor 1 agonists.Quarta, C. ; Schneider, R. ; Tschöp, M.H.
Epigenetic ON/OFF switches for obesity.Telieps, T. ; Köhler, M. ; Treise, I. ; Förtsch, K. ; Adler, T. ; Busch, D.H. ; Hrabě de Angelis, M. ; Verschoor, A. ; Adler, K. ; Bonifacio, E. ; Ziegler, A.-G.
Longitudinal frequencies of blood leukocyte sub-populations differ between NOD and NOR mice, but do not predict diabetes in NOD mice.Ost, M. ; Coleman, V. ; Voigt, A. ; van Schothorst, E.M. ; Keipert, S. ; van der Stelt, I. ; Ringel, S. ; Graja, A. ; Ambrosi, T. ; Kipp, A.P. ; Jastroch, M. ; Schulz, T.J. ; Keijer, J. ; Klaus, S.
Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action.Haar, J. ; Contrant, M. ; Bernhardt, K. ; Feederle, R. ; Diederichs, S. ; Pfeffer, S. ; Delecluse, H.J.
The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation.Grabner, G.F. ; Eichmann, T.O. ; Wagner, B. ; Gao, Y. ; Farzi, A. ; Taschler, U. ; Radner, F.P. ; Schweiger, M. ; Lass, A. ; Holzer, P. ; Zinser, E. ; Tschöp, M.H. ; Yi, C.-X. ; Zimmermann, R.
Deletion of monoglyceride lpase in astrocytes attenuates lipopolysaccharide-induced neuroinflammation.Huerta-Cepas, J. ; Szklarczyk, D. ; Forslund, K. ; Cook, H. ; Heller, D. ; Walter, M.C. ; Rattei, T. ; Mende, D.R. ; Sunagawa, S. ; Kuhn, M. ; Jensen, L.J. ; von Mering, C. ; Bork, P.
eggNOG 4.5: A hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences.Clemmensen, C. ; Müller, T.D. ; Finan, B. ; Tschöp, M.H. ; DiMarchi, R.
Current and emerging treatment options in diabetes care.