IDO Labor Gelber Handschuh

New Research Findings, IDO,

Unraveling the Mode of Action of Tirzepatide

Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes. Although the drug is designed to activate receptors…

Timo Müller Werner-Creutzfeldt-Preis 2023 Auszeichnung, Mai 2023 Berlin

Awards & Grants, IDO,

Timo Müller Awarded with Werner Creutzfeldt Prize

The German Diabetes Society (DDG) awards this year's Werner Creutzfeldt Prize to Helmholtz Munich scientist PD Dr Timo Müller for his exceptional work in the research field of Incretin-based diabetes and obesity. This is already the second time in a…

New Research Findings, IDO,

Cited1 links sex and metabolic hormones to protect against obesity

Sex differences exist in the regulation of energy homeostasis, the organism’s mechanism to keep a stable body weight. Current studies indicate for instance that female mammals, including humans, are better protected against metabolic diseases during…

Center Template, Icon, Featured Publication, Diabetes

Featured Publication, IDO,

Messages from adipose tissue

Identification of a previously unknown function of adipose tissue in insulin secretion.

Scientists at Helmholtz Munich and the University of Augsburg have made an important breakthrough in better understanding early processes in the development of…

Center Template, Icon, Featured Publication, Diabetes

Featured Publication, IDR, IDO,

Diabetes type 2: New biomarkers for patient classification and intervention prediction identified

Type 2 diabetes disease progression and successful intervention depend on individual’s unique clinical, genetic, genomic, and environmental information partly represented by gene expression patterns. An international team of researchers around…

Prof. Dr. Dr. h.c. Matthias H. Tschöp, wissenschaftlicher Geschäftsführer Helmholtz Zentrum München

IDO,

Matthias Tschöp successfully completed the ERC Project “Targeting Hypothalamic inFlammation in obesity and diabetes (HypoFlam)”

The key objective of this proposal was to further dissect and characterize the cell-specific neuroendocrine signaling mechanisms that underlie the development of obesity, diabetes, and their co-morbidities, with a special emphasis on hypothalamic…