Research within the Institute of Epigenetics and Stem Cells aims at determining how stem cells originate in vivo and at establishing epigenetic principles behind changes in cellular plasticity and genome reprogramming. They study how the transitions in cell potency and cell fate are regulated by chromatin-mediated processes using a variety of approaches including quantitative imaging, modeling, functional genomics and cell biology. Understanding the molecular mechanisms behind the maintenance and manipulation of cellular plasticity will have strong implications in regenerative medicine and disease, and will help in deciphering human reproduction and infertility.

Stephan Hamperl Chromatin dynamics and genome stability

Eva Hörmanseder Maintaining and Reprogramming Cell Fates

Antonio Scialdone Physics- and data-based modeling of cellular decision making

Maria Elena Torres-Padilla Epigenetics and cell fate in early mammalian development

Microscopy Core