Scientific Focus

Research Group "Lung Aging"

The Lehmann Lab aims to understand how aging predisposes the lung to the development of chronic lung diseases such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD). In particular, the lab investigates the contribution of cellular aging pathways such as cellular senescence in chronic lung diseases. We aim to understand how cellular aging affects stem cell capacities and cell-cell crosstalk, especially between immune cells and stem cells. In order to allow the aging lung to efficiently repair, we aim to develop biomarkers as well as therapeutic strategies targeting cellular aging phenotypes, thereby opening novel avenues for the diagnosis and treatment of chronic lung diseases.