Scientific Focus

  • The overall aim of Molecular Targets and Therapeutics Center is to unravel novel pathways and molecular mechanisms controlling physiological and disease-related cellular processes, and to use this information to identify novel targets for therapeutic intervention. We have discovered and characterized novel pathways and molecular mechanisms in cell death, immunity, epigenetics and RNA regulation. Advanced integrative structural biology techniques are being used to unravel molecular mechanisms as a basis for structure-based drug discovery. The vision of the Center is to ultimately translate this knowledge into effective and safe new therapies.