Martin Mück-Häusl landscape portrait

Deputy Director

Dr. Martin Mück-Häusl

“Genetic engineering is my playground!” 

Group Leader of the research group Genetic Perturbations and Systems (upcoming)

Academic Career and Research Areas

Martin holds a Master’s degree in Biochemistry from the Technical University of Munich (TUM) and completed his PhD in 2011 at the Max von Pettenkofer Institute of Ludwig-Maximilians-University (LMU) Munich, where he focused on advanced genetic engineering methods for viral vector development in the context of gene‑therapeutic applications. 

After joining the Institute of Virology at Helmholtz Munich in 2012, he focused on modulating genetic factors and engineering complex systems in the context of vaccination as well as experimental cell culture and animal models. Starting in 2018 at the Institute of Regenerative Biology and Medicine (IRBM) as a Senior Scientist, he worked under Dr. Adrian Fischer, developing genetic tools for investigating the extracellular matrix and mechanistic analyses of mesothelial cells in the context of lung fibrosis.

In 2024, he was recruited by Prof. Dr. Herbert Schiller as Deputy Director of the Research Unit of Precision Regenerative Medicine (PRM), focusing his research on mechanistic investigations of gene programs identified through LLM‑assisted statistical analysis of large‑scale, multi‑omics datasets from mouse models and human precision‑cut lung slices (PCLS) in the context of lung fibrosis and lung aging. 

Skills

Genetic engineering  Vector Development  Extracellular Matrix Detection  Regenerative Medicine and Translation Genetic Manipulations and Perturbations  Nucleic Acids Transfer Genetic Systems Coding

Professional Background

2026

Group Leader for the research group Genetic Perturbations and Systems (GPS) within PRM

2024

Deputy Director, Research Unit for Precision Regenerative Medicine (PRM), Helmholtz Munich

2018

2018–2024 Senior Scientist, Institute of Regenerative Medicine and Biology (IRBM), Helmholtz Munich

2012

2012–2017 Postdoctoral Scientist, Institute of Virology, Helmholtz Munich

2011

2011–2012 Postdoctoral Scientist, Max von Pettenkofer-Institute, Ludwig-Maximilians-University (LMU) Munich

2011

2007-2011 Doctoral thesis in Virology, Max von Pettenkofer-Institute, Ludwig-Maximilians-University (LMU) Munich

2007

M.Sc. in Biochemistry, Technical University of Munich (TUM)

Patents

  1. Modulators of Mesothelial ECM movement (US20250333482) - 2022

  2. Novel recombinant hbv reporter system (US10912827B2) - 2019 

  3. Means and methods for treating HBV (US10912827B2) - 2017

Selected Publications

2025 Nature Communications

Kadri S.*, Fischer A.*, Mück-Häusl M.*, Han W.* et. al.

A mesothelial differentiation gateway drives fibrosis
2025 Nature Communications

Fischer A.*, Han W.*, Hu S.*, Mück-Häusl M.*, Wannemacher J.* et. al.

Targeting pleuro-alveolar junctions reverses lung fibrosis in mice