Group Leader Immunotherapeutic Technologies
Dr. Rer. Nat. Gerald Burgstaller
"My vision is to discover and develop innovative therapeutics tackling chronic lung diseases and identify novel molecular targets as well as elucidating the mode-of-action. This only can be achieved by highly multi- and interdisciplinary work and thriving academic, clinical and industrial collaborations."
Skills
Chronic Lung Diseases Cell Biology Extracellular MatrixDrug Discovery Human Lung Disease Models Advanced Microscopy
Professional Background
Principal Investigator/Research group leader at Helmholtz Munich, Institute of Lung Health and Immunity, Comprehensive Pneumology Center (CPC)
Staff Scientist at Helmholtz Munich, Head of Imaging Core Facility, Institute of Lung Biology and Disease, Comprehensive Pneumology Center (CPC)
Postdoc at Helmholtz Munich, Head of Imaging Core Facility, Institute of Lung Biology and Disease, Comprehensive Pneumology Center (CPC)
Postdoc at Helmholtz Munich, Institute of Clinical Molecular Biology and Tumor Genetics
Postdoc at Max Perutz Laboratories Vienna, Austria
Doctorial researcher at Austrian Academy of Sciences in Salzburg, Austria
Publications
Sieber-Schaefer, F. ; Jiang, M. ; Kromer, A.P.E. ; Nguyen, A. ; Molbay, M. ; Pinto Carneiro, S. ; Juergens, D. ; Burgstaller, G. ; Popper, B. ; Winkeljann, B. ; Merkel, O.M.
Machine learning-enabled polymer discovery for enhanced pulmonary siRNA delivery.Stoleriu, M.-G. ; Ansari, M. ; Strunz, M. ; Schamberger, A.C. ; Heydarian, M. ; Gabriel, C. ; Najak, A. ; Disovic, A. ; Schneider, J. ; Gerckens, M. ; Burgstaller, G. ; Ding, Y. ; Doryab, A. ; Voss, C. ; Ketscher, C. ; Sienel, W. ; Kauke, T. ; Fertmann, J. ; Schneider, C. ; Behr, J. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Schubert, B. ; Hauck, S.M. ; Hatz, R. ; Schmid, O. ; Stöger, T. ; Schiller, H. ; Hilgendorff, A.
Development of advanced in-vitro human bronchial epithelial models and lung cell atlas in COPD enabled by thoracic surgery translational research.Müller, J.T. ; Kromer, A.P.E. ; Ezaddoustdar, A. ; Alexopoulos, I. ; Steinegger, K.M. ; Porras-Gonzalez, D.L. ; Berninghausen, O. ; Beckmann, R. ; Braubach, P. ; Burgstaller, G. ; Wygrecka, M. ; Merkel, O.M.
Nebulization of RNA-loaded micelle-embedded polyplexes as a potential treatment of idiopathic pulmonary fibrosis.Bukas, C. ; Subramanian, H. ; See, F. ; Steinchen, C. ; Ezhov, I. ; Boosarpu, G. ; Asgharpour, S. ; Burgstaller, G. ; Lehmann, M. ; Kofler, F. ; Piraud, M.
MultiOrg: A Multi-rater organoid-detection dataset.Yang, L. ; Liu, Q. ; Kumar, P. ; Sengupta, A. ; Farnoud, A. ; Shen, R. ; Trofimova, D. ; Ziegler, S. ; Davoudi, N. ; Doryab, A. ; Yildirim, A.Ö. ; Diefenbacher, M. ; Schiller, H. ; Razansky, D. ; Piraud, M. ; Burgstaller, G. ; Kreyling, W.G. ; Isensee, F. ; Rehberg, M. ; Stöger, T. ; Schmid, O.
LungVis 1.0: An automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages.Burgy, O. ; Mayr, C.H. ; Schenesse, D. ; Fousekis Papakonstantinou, E. ; Ballester, B. ; Sengupta, A. ; She, Y. ; Hu, Q. ; Melo-Narváez, M.C ; Jain, E. ; Pestoni, J. ; Mozurak, M. ; Estrada-Bernal, A. ; Onwuka, U. ; Coughlan, C. ; Parimon, T. ; Chen, P. ; Heimerl, T. ; Bange, G. ; Schmeck, B.T. ; Lindner, M. ; Hilgendorff, A. ; Ruppert, C. ; Guenther, A. ; Mann, M. ; Yildirim, A.Ö. ; Eickelberg, O. ; Jung, A.L. ; Schiller, H. ; Lehmann, M. ; Burgstaller, G. ; Königshoff, M.
Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis.Stoleriu, M.-G. ; Ansari, M. ; Strunz, M. ; Schamberger, A.C. ; Heydarian, M. ; Ding, Y. ; Voss, C. ; Schneider, J.J. ; Gerckens, M. ; Burgstaller, G. ; Castelblanco, A. ; Kauke, T. ; Fertmann, J. ; Schneider, C. ; Behr, J. ; Lindner, M. ; Stacher-Priehse, E. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Schubert, B. ; Hauck, S.M. ; Schmid, O. ; Hatz, R.A. ; Stöger, T. ; Schiller, H. ; Hilgendorff, A.
COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors.Mayr, C. ; Sengupta, A. ; Asgharpour, S. ; Ansari, M. ; Pestoni, J. ; Ogar, P. ; Angelidis, I. ; Liontos, A. ; Rodriguez-Castillo, J.A. ; Lang, N.J. ; Strunz, M. ; Porras-Gonzalez, D.L. ; Gerckens, M. ; De Sadeleer, L.J. ; Oehrle, B. ; Viteri-Alvarez, V. ; Fernandez, I.E. ; Tallquist, M. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Stoleriu, M.G. ; Behr, J. ; Kneidinger, N. ; Wuyts, W.A. ; Wasnick, R. ; Yildirim, A.Ö. ; Ahlbrecht, K. ; Morty, R.E. ; Samakovlis, C. ; Theis, F.J. ; Burgstaller, G. ; Schiller, H.
Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts.