Publications
Rogalsky, S.P. ; Hodyna, D. ; Semenyuta, I. ; Frasinyuk, M. ; Tarasyuk, O. ; Riabov, S. ; Kobrina, L. ; Tetko, I.V. ; Metelytsia, L.
Antibacterial activity of 1-dodecylpyridinium tetrafluoroborate and its inclusion complex with sulfobutyl ether-β-cyclodextrin against MDR acinetobacter Baumannii strains.Higuera-Rodriguez, R.A. ; De Pascali, M.C. ; Aziz, M. ; Sattler, M. ; Rant, U. ; Kaiser, W.J.
Kinetic FRET assay to measure binding-induced conformational changes of nucleic acids.Aretz, J. ; Aziz, M. ; Strohmeyer, N. ; Sattler, M. ; Fässler, R.
Talin and kindlin use integrin tail allostery and direct binding to activate integrins.Rössler, J. ; Pich, D. ; Krähling, V. ; Becker, S. ; Keppler, O.T. ; Zeidler, R. ; Hammerschmidt, W.
SARS-CoV-2 and Epstein-Barr Virus-like particles associate and fuse with extracellular vesicles in virus neutralization tests.Fukumura, K. ; Sperotto, L. ; Seuss, S. ; Kang, H.-S. ; Yoshimoto, R. ; Sattler, M. ; Mayeda, A.
SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns.Kitel, R. ; Surmiak, E. ; Borggräfe, J. ; Kalinowska-Tluscik, J. ; Golik, P. ; Czub, M. ; Uzar, W. ; Musielak, B. ; Madej, M.G. ; Popowicz, G.M. ; Dubin, G. ; Holak, T.A.
Discovery of inhibitory fragments that selectively target spire2-FMN2 interaction.Schmidt, H. ; Raj, T. ; O´Neill, T.J. ; Muschaweckh, A. ; Giesert, F. ; Negraschus, A. ; Höfig, K.P. ; Behrens, G. ; Esser, L. ; Baumann, Christina ; Feederle, R. ; Plaza-Sirvent, C. ; Geerlof, A. ; Gewies, A. ; Isay, S.E. ; Ruland, J. ; Schmitz, I. ; Wurst, W. ; Korn, T. ; Krappmann, D. ; Heissmeyer, V.
Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.Vincenzi, M. ; Kremić, A. ; Jouve, A. ; Lattanzi, R. ; Miele, R. ; Benharouga, M. ; Alfaidy, N. ; Migrenne-Li, S. ; Kanthasamy, A.G. ; Porcionatto, M. ; Ferrara, N. ; Tetko, I.V. ; Desaubry, L. ; Nebigil, C.G.
Therapeutic potential of targeting prokineticin receptors in diseases.Aschenbrenner, I. ; Siebenmorgen, T. ; Lopez, A. ; Parr, M. ; Ruckgaber, P. ; Kerle, A. ; Rührnößl, F. ; Catici, D. ; Haslbeck, M. ; Frishman, D. ; Sattler, M. ; Zacharias, M. ; Feige, M.J.
Assembly-dependent structure formation shapes human interleukin-23 versus interleukin-12 secretion.Pustelny, K. ; Grygier, P. ; Barzowska, A. ; Pucelik, B. ; Matsuda, A. ; Mrowiec, K. ; Slugocka, E. ; Popowicz, G.M. ; Dubin, G. ; Czarna, A.
Binding mechanism and biological effects of flavone DYRK1A inhibitors for the design of new antidiabetics.Nakamura, T. ; Mishima, E. ; Yamada, N. ; Mourao, A. ; Trümbach, D. ; Doll, S. ; Wanninger, J. ; Lytton, E. ; Sennhenn, P. ; Nishida Xavier da Silva, T. ; Angeli, J.P.F. ; Sattler, M. ; Proneth, B. ; Conrad, M.
Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation.Šmelko, A. ; Blahut, J. ; Reif, B. ; Tosner, Z.
Performance of the cross-polarization experiment in conditions of radiofrequency field inhomogeneity and slow to ultrafast magic angle spinning (MAS).Witzenberger, M. ; Burczyk, S. ; Settele, D. ; Mayer, W. ; Welp, L.M. ; Heiss, M. ; Wagner, M. ; Monecke, T. ; Janowski, R. ; Carell, T. ; Urlaub, H. ; Hauck, S.M. ; Voigt, A. ; Niessing, D.
Human TRMT2A methylates tRNA and contributes to translation fidelity.Cardoso Micu Menezes, F.M. ; Popowicz, G.M.
When catchers meet - a computational study on the dimerization of the Buckycatcher.Roll, W. ; Müther, M. ; Böning, G. ; Delker, A. ; Warneke, N. ; Gildehaus, F.J. ; Schäfers, M. ; Stummer, W. ; Zeidler, R. ; Reulen, H.J. ; Stegger, L.
First clinical experience with fractionated intracavitary radioimmunotherapy using [177Lu]Lu-6A10-Fab fragments in patients with glioblastoma: A pilot study.Kolonko-Adamska, M. ; Zawadzka-Kazimierczuk, A. ; Bartosińska-Marzec, P. ; Koźmiński, W. ; Popowicz, G.M. ; Krężel, A. ; Ożyhar, A. ; Greb-Markiewicz, B.
Interaction patterns of methoprene-tolerant and germ cell-expressed Drosophila JH receptors suggest significant differences in their functioning.Mishima, E. ; Nakamura, T. ; Zheng, J. ; Zhang, W. ; Mourao, A. ; Sennhenn, P. ; Conrad, M.
DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition.Blahut, J. ; Brandl, M.J. ; Sarkar, R. ; Reif, B. ; Tošner, Z.
Optimal control derived sensitivity-enhanced CA-CO mixing sequences for MAS solid-state NMR – Applications in sequential protein backbone assignments.Marciniak, M. ; Mroz, P. ; Napolitano, V. ; Kalel, V.C. ; Fino, R. ; Pykacz, E. ; Schliebs, W. ; Plettenburg, O. ; Erdmann, R. ; Sattler, M. ; Popowicz, G.M. ; Dawidowski, M.
Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template.Nakamura, T. ; Hipp, C. ; Santos Dias Mourão, A. ; Borggräfe, J. ; Aldrovandi, M. ; Henkelmann, B. ; Wanninger, J. ; Mishima, E. ; Lytton, E. ; Emler, D. ; Proneth, B. ; Sattler, M. ; Conrad, M.
Phase separation of FSP1 promotes ferroptosis.Pradhan, T. ; Sarkar, R. ; Meighen-Berger, K.M. ; Feige, M.J. ; Zacharias, M. ; Reif, B.
Mechanistic insights into the aggregation pathway of the patient-derived immunoglobulin light chain variable domain protein FOR005.Svilenov, H.L. ; Delhommel, F. ; Siebenmorgen, T. ; Rührnößl, F. ; Popowicz, G.M. ; Reiter, A. ; Sattler, M. ; Brockmeyer, C. ; Buchner, J.
Extrinsic stabilization of antiviral ACE2-Fc fusion proteins targeting SARS-CoV-2.Cardoso Micu Menezes, F.M. ; Popowicz, G.M.
A buckycatcher in solution-a computational perspective.Agam, G. ; Gebhardt, C. ; Popara, M. ; Mächtel, R. ; Folz, J. ; Ambrose, B. ; Chamachi, N. ; Chung, S.Y. ; Craggs, T.D. ; de Boer, M. ; Grohmann, D. ; Ha, T. ; Hartmann, A. ; Hendrix, J. ; Hirschfeld, V. ; Hübner, C.G. ; Hugel, T. ; Kammerer, D. ; Kang, H.-S. ; Kapanidis, A.N. ; Krainer, G. ; Kramm, K. ; Lemke, E.A. ; Lerner, E. ; Margeat, E. ; Martens, K. ; Michaelis, J. ; Mitra, J. ; Moya Muñoz, G.G. ; Quast, R.B. ; Robb, N.C. ; Sattler, M. ; Schlierf, M. ; Schneider, J. ; Schröder, T. ; Sefer, A. ; Tan, P.S. ; Thurn, J. ; Tinnefeld, P. ; van Noort, J. ; Weiss, S. ; Wendler, N. ; Zijlstra, N. ; Barth, A. ; Seidel, C.A.M. ; Lamb, D.C. ; Cordes, T.
Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins.Andronov, M. ; Voinarovska, V. ; Andronova, N. ; Wand, M. ; Clevert, D.A. ; Schmidhuber, J.
Reagent prediction with a molecular transformer improves reaction data quality.Escher, B.I. ; Altenburger, R. ; Blüher, M. ; Colbourne, J.K. ; Ebinghaus, R. ; Fantke, P. ; Hein, M. ; Köck, W. ; Kümmerer, K. ; Leipold, S. ; Li, X. ; Scheringer, M. ; Scholz, S. ; Schloter, M. ; Schweizer, P.J. ; Tal, T. ; Tetko, I.V. ; Traidl-Hoffmann, C. ; Wick, L.Y. ; Fenner, K.
Modernizing persistence-bioaccumulation-toxicity (PBT) assessment with high throughput animal-free methods.Grygier, P. ; Pustelny, K. ; Nowak, J. ; Golik, P. ; Popowicz, G.M. ; Plettenburg, O. ; Dubin, G. ; Cardoso Micu Menezes, F.M. ; Czarna, A.
Silmitasertib (CX-4945), a clinically used CK2-kinase inhibitor with additional effects on GSK3β and DYRK1A kinases: A structural perspective.Günsel, U. ; Klöpfer, K. ; Häusler, E. ; Hitzenberger, M. ; Bölter, B. ; Sperl, L.E. ; Zacharias, M. ; Soll, J. ; Hagn, F.
Structural basis of metabolite transport by the chloroplast outer envelope channel OEP21.Mohamad, M. ; Goricanec, D. ; Wagner, G. ; Hagn, F.
NMR sample optimization and backbone assignment of a stabilized neurotensin receptor.Calonaci, N. ; Bernetti, M. ; Jones, A. ; Sattler, M. ; Bussi, G.
Molecular dynamics simulations with grand-canonical reweighting suggest cooperativity effects in RNA structure probing experiments.Liesenhoff, C. ; Paulus, S.M. ; Havertz, C. ; Geerlof, A. ; Priglinger, S. ; Priglinger, C.S. ; Ohlmann, A.
Endogenous galectin-1 modulates cell biological properties of immortalized retinal pigment epithelial cells in vitro.Shi, E. ; Wu, Z. ; Karaoglan, B.S. ; Schwenk-Zieger, S. ; Kranz, G. ; Abdul Razak, N. ; Reichel, C.A. ; Canis, M. ; Baumeister, P. ; Zeidler, R. ; Gires, O.
5'-Ectonucleotidase CD73/NT5E supports EGFR-mediated invasion of HPV-negative head and neck carcinoma cells.Klambauer, G. ; Clevert, D.A. ; Shah, I. ; Benfenati, E. ; Tetko, I.V.
Introduction to the special issue: AI meets toxicology.Enders, L. ; Siklos, M. ; Borggräfe, J. ; Gaussmann, S. ; Koren, A. ; Malik, M. ; Tomek, T. ; Schuster, M. ; Reiniš, J. ; Hahn, E. ; Rukavina, A. ; Reicher, A. ; Casteels, T. ; Bock, C. ; Winter, G.E. ; Hannich, J.T. ; Sattler, M. ; Kubicek, S.
Pharmacological perturbation of the phase-separating protein SMNDC1.Ebersberger, S. ; Hipp, C. ; Mulorz, M.M. ; Buchbender, A. ; Hubrich, D. ; Kang, H.-S. ; Martinez Lumbreras, S. ; Kristofori, P. ; Sutandy, F.X.R. ; Llacsahuanga Allcca, L. ; Schönfeld, J. ; Bakisoglu, C. ; Busch, A. ; Hänel, H. ; Tretow, K. ; Welzel, M. ; Di Liddo, A. ; Möckel, M.M. ; Zarnack, K. ; Ebersberger, I. ; Legewie, S. ; Luck, K. ; Sattler, M. ; König, J.
FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.Troisi, R. ; Napolitano, V. ; Rossitto, E. ; Osman, W. ; Nagano, M. ; Wakui, K. ; Popowicz, G.M. ; Yoshimoto, K. ; Sica, F.
Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide.Soni, K. ; Jagtap, P.K. ; Martinez Lumbreras, S. ; Bonnal, S. ; Geerlof, A. ; Stehle, R. ; Simon, B. ; Valcárcel, J. ; Sattler, M.
Structural basis for specific RNA recognition by the alternative splicing factor RBM5.Vistoli, G. ; Manelfi, C. ; Talarico, C. ; Fava, A. ; Warshel, A. ; Tetko, I.V. ; Apostolov, R. ; Ye, Y. ; Latini, C. ; Ficarelli, F. ; Palermo, G. ; Gadioli, D. ; Vitali, E. ; Varriale, G. ; Pisapia, V. ; Scaturro, M. ; Coletti, S. ; Gregori, D. ; Gruffat, D. ; Leija, E. ; Hessenauer, S. ; Delbianco, A. ; Allegretti, M. ; Beccari, A.R.
MEDIATE - Molecular DockIng at homE: Turning collaborative simulations into therapeutic solutions.Roca-Martínez, J. ; Dhondge, H. ; Sattler, M. ; Vranken, W.F.
Deciphering the RRM-RNA recognition code: A computational analysis.Gui, X. ; Feng, S. ; Li, Z. ; Li, Y. ; Reif, B. ; Shi, B. ; Niu, Z.
Liquid-liquid phase separation of amyloid-β oligomers modulates amyloid fibrils formation.Zanuttigh, E. ; Derderian, K. ; Güra, M. ; Geerlof, A. ; Di Meo, I. ; Cavestro, C. ; Hempfling, S. ; Ortiz Collazos, S. ; Mauthe, M. ; Kmiec, T. ; Cammarota, E. ; Panzeri, M.C. ; Klopstock, T. ; Sattler, M. ; Winkelmann, J. ; Messias, A.C. ; Iuso, A.
Identification of autophagy as a functional target suitable for the pharmacological treatment of mitochondrial membrane protein-associated neurodegeneration (MPAN) in vitro.Molitor, L. ; Klostermann, M. ; Bacher, S. ; Merl-Pham, J. ; Spranger, N. ; Burczyk, S. ; Ketteler, C. ; Rusha, E. ; Tews, D. ; Pertek, A. ; Proske, M. ; Busch, A. ; Reschke, S. ; Feederle, R. ; Hauck, S.M. ; Blum, H. ; Drukker, M. ; Fischer-Posovszky, P. ; König, J. ; Zarnack, K. ; Niessing, D.
Depletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies.Keil, P. ; Wulf, A. ; Kachariya, N. ; Reuscher, S. ; Huhn, K. ; Silbern, I. ; Altmüller, J. ; Keller, M. ; Stehle, R. ; Zarnack, K. ; Sattler, M. ; Urlaub, H. ; Sträßer, K.
Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.Delhommel, F. ; Martinez Lumbreras, S. ; Sattler, M.
Combining NMR, SAXS and SANS to characterize the structure and dynamics of protein complexes.