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3d rendering of Human cell

Stem Cells, IES, Computational Health, ICB,

A New Frontier in Human Development Research: Advanced 3D Gastruloid Models Enable Exploration of Early Lineages

A Powerful Tool for Modeling Early Human Development

Stem Cells, IES,

New paper from Stephan Hamperl lab

"Transcription-replication conflicts drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery".

Nucleic Acids Research. 28 February 2025.

Werner M*, Trauner M*, Schauer T., Ummethum H., Márquez-Gómez E.,…

Art_the_IES_IMG_6586

Stem Cells, IES,

New Review on Epigenome dynamics

"Epigenome dynamics in early mammalian embryogenesis".

Nature Reviews Genetics. 27 February 2025.

Adam Burton & Maria Elena Torres-Padilla.

Epigenetics Summer Interns 2024 - poster

Stem Cells, IES, Computational Health, ICB, AIH, Molecular Targets and Therapeutics, IFE,

Call for Applications CLOSED

Epigenetics Summer Internship Call for Applications CLOSED

Maria Elena Torres Padilla AI generated

Maria-Elena Torres-Padilla Honored With the Leibniz Prize 2025

International Top Scientist from Helmholtz Munich Honored with Germany's Most Prestigious Research Award

Epigenetic modification representation

IES, IFE,

FROM DNA TO PHENOTYPE Workshop. Join us in Jaen!

This multidisciplinary workshop will bring together 15 OUTSTANDING SPEAKERS with the objective of tackling the various dimensions of epigenetic mechanisms in resilience and adaptation, by providing a platform for researchers to exchange knowledge,…

Abe_et_al_2022_Cell_Reports_MA_Plot

How our genes are read at the beginning of life

Researchers from the Institute for Epigenetics and Stem Cells at Helmholtz Munich studied RNA Polymerase II (Pol II) in early mouse embryos and shed light on transcriptional elongation during zygotic genome activation (ZGA), a key process of…

Human embryo on the stage of 16 cells on background with DNA

IES, IFE,

The use of embryo models to study development - a perspective

In the perspective article "In preprints: improving and interrogating embryo models", Antonio Scialdone from the Institute for Epigenetics and Stem Cells, the Institute of Functional Epigenetics, and the Institute of Computational Biology at…

Light Bulbs with Workshop Concept

The fourth Epigenetics Retreat was a great success

The fourth epigenetics@HelmholtzMunich retreat took place on November 7th – 8th 2022 close to Lake Ammersee in Bavaria.