Academic Career and Research Areas
Mohammadali Khan Mirzaei's research integrates experimental and computational approaches to gain a deep understanding of complex phage-host interactions with the aim of developing next-generation therapeutics to treat multi-drug resistant infections and engineer the human microbiome. To achieve this, he develops and combines a diverse array of methodologies, including single-cell techniques, -omics approaches, metabolic labeling, and model systems.
Professional Background
Vice head of the research unit/ Team leader at the Institute of Virology, Helmholtz Zentrum München and Technical University of Munich, Germany
Senior postdoctoral researcher at the Institute of Virology, Helmholtz Zentrum München and Technical University of Munich, Germany
Research topic: Novel phage-based therapeutics for treating multi-drug resistant infections and engineering the human microbiome
Postdoctoral researcher at the Department of Microbiology and Imunology, McGill University, Montreal, Canada
Research topic: Phage-bacteria interactions in the human gut and their role in health and disease
Ph.D. in Molecular Genetics at the Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden
Thesis: The efficacy of bacterial viruses against multi-resistant Escherichia coli: from isolation to Pharmacology
M.Sc. in Molecular life sciences at the Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden
Thesis: Isolation and characterization of phages against multi-resistant Escherichia coli
Publications
Rupp, M. ; Ferry, T. ; Khan Mirzaei, M. ; Alt, V. ; Deng, L. ; Walter, N.
Bakteriophagen zur Behandlung muskuloskelettaler Infektionen – Eine Übersicht zu klinischem Einsatz, offenen Fragen und rechtlichem Rahmen.Huang, W. ; Khan Mirzaei, M. ; Deng, L.
Comparative evaluation of long-term preservation methods for morphologically distinct bacteriophages.Ahmadi, A. ; Yousefimashouf, R. ; Mohammadi, A. ; Nikkhoo, B. ; Shokoohizadeh, L. ; Khan Mirzaei, M. ; Alikhani, M.Y. ; Sheikhesmaili, F. ; Khodaei, H.
Investigating the expression of anti/pro-inflammatory cytokines in the pathogenesis and treatment of ulcerative colitis and its association with serum level of vitamin D.