Academic Career and Research Areas
Jinling Xue possesses an interdisciplinary background in Environmental Microbiology and Human Health Risk Assessment, which she leverages to advance the field of virome research. Her work investigates the critical contributions of virome to both natural ecological circulations and the development of human autoimmune diseases, such as Type 2 Diabetes (T2D) and Graft-versus-Host Disease (GvHD). By utilizing multi-omics approaches and Deep-Learning-Based protein structural prediction, she has uncovered a series of novel bacteriophage-encoded genes that play pivotal roles in short-chain fatty acid biosynthesis (BCoAT) and long-chain hydrocarbon degradation (various Alkane Hydroxylases). Her current research focuses on expanding the understanding of microbial ecology and pathogenesis and also on opening new avenues for therapeutic interventions via phage-involved treatments.
Professional Background
University-funded Senior Postdoc Researcher in the Chair of Microbial Disease Prevention, School of Life Sciences, Technical Univ. of Munich, Freising, Germany
Post-Doc researcher in Institute of Virology, Helmholtz Zentrum München, Germany
Chinese-German Helmholtz Association Postdoctoral Fellow, Neuherberg, Germany
Ph.D., top 5% of students got Master plus PhD program, Tsinghua University, Beijing, China
B.Sc., summa cum laude, School of Environmental Sciences and Technology, Shandong University, Jinan, China
Publications
Thiele Orberg, E. ; Meedt, E. ; Hiergeist, A. ; Xue, J. ; Heinrich, P.C. ; Ru, J. ; Ghimire, S. ; Miltiadous, O. ; Lindner, S. ; Tiefgraber, M. ; Göldel, S. ; Eismann, T. ; Schwarz, A. ; Göttert, S. ; Jarosch, S. ; Steiger, K. ; Schulz, C. ; Gigl, M. ; Fischer, J.C. ; Janssen, K.P. ; Quante, M. ; Heidegger, S. ; Herhaus, P. ; Verbeek, M. ; Ruland, J. ; van den Brink, M.R.M. ; Weber, D. ; Edinger, M. ; Wolff, D. ; Busch, D.H. ; Kleigrewe, K. ; Herr, W. ; Bassermann, F. ; Gessner, A. ; Deng, L. ; Holler, E. ; Poeck, H.
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation.Xue, J. ; Mirzaei, M.K. ; Costa, R. ; Smith, S. ; Tiamani, K. ; Ma, T. ; Deng, L.
Human virome in health and disease.Luo, S. ; Ru, J. ; Khan Mirzaei, M. ; Xue, J. ; Peng, X. ; Ralser, A. ; Hadi, J.L. ; Mejías-Luque, R. ; Gerhard, M. ; Deng, L.
Helicobacter pylori infection alters gut virome by expanding temperate phages linked to increased risk of colorectal cancer.