Human Microbiome
We want to understand the functional basis of health promoting microbes from the human microbiome, focusing on the barrier organs skins and respiratory system. Based on samples from cohorts of healthy children and adults, provided by colleges at Helmholtz Munich and beyond, we predict core microbiota which provide health promoting functions. Those microbiota are isolated using high throughput cultivation based approaches and tested in vitro for their functional potentials, which is further confirmed using cell culture and animal models. Strategies to promote the abundance and activity of those microbiota under dysbioitc conditions will be proposed based on the microbial geno- and phenotypes.
We want to understand the functional basis of health promoting microbes from the human microbiome, focusing on the barrier organs skins and respiratory system. Based on samples from cohorts of healthy children and adults, provided by colleges at Helmholtz Munich and beyond, we predict core microbiota which provide health promoting functions. Those microbiota are isolated using high throughput cultivation based approaches and tested in vitro for their functional potentials, which is further confirmed using cell culture and animal models. Strategies to promote the abundance and activity of those microbiota under dysbioitc conditions will be proposed based on the microbial geno- and phenotypes.
