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LISA

The LISA study is a long-term, population-based prospective birth cohort study comprising 3094 children from four regions of Germany (Munich, Leipzig, Wesel, Bad Honnef). The aims of the LISA study are to monitor the development and natural course of atopic diseases and to investigate the influence of life-style and environmental factors. Further topics such as mental well-being, lung function, nutrition, body composition and physical activity were added later and the LISA study is now further contributing data in a multitude of collaborative efforts to further understand childhood allergies, growth and genetics.

Our website for the participants of the LISA study: www.lisastudie.de (in German).

The LISA study is a long-term, population-based prospective birth cohort study comprising 3094 children from four regions of Germany (Munich, Leipzig, Wesel, Bad Honnef). The aims of the LISA study are to monitor the development and natural course of atopic diseases and to investigate the influence of life-style and environmental factors. Further topics such as mental well-being, lung function, nutrition, body composition and physical activity were added later and the LISA study is now further contributing data in a multitude of collaborative efforts to further understand childhood allergies, growth and genetics.

Our website for the participants of the LISA study: www.lisastudie.de (in German).

About our Cohort Study

The LISA study is a prospective, multi-center and population-based birth cohort, which recruited children born between November 1997 to January 1999 and focuses on the influence of Life-style factors on the Development of the Immune System and Allergies in East and West Germany (LISA).

3097 healthy and full-term newborns were enrolled in the four study regions, Munich (n = 1467), Leipzig (n = 976), Wesel (n = 348) and Bad Honnef (n = 306) and followed up at 0.5, 1, 1.5, 2, 4, 6, 10, 15, 20 and now 25 years of age, as well as during the COVID-19 pandemic.

General

  • To determine the influence of life-style factors, environmental exposures, and health-related behaviour on the development of the immune system and the incidence of allergic diseases in children.
  • To determine the influence of traffic emissions and genetics

The 25-year-follow up will start at the beginning of 2023.

 

Study region Munich

  • Helmholtz Munich – Institute of Epidemiology: Marie Standl

Wesel

  • Marien-Hospital Wesel, Department of Pediatrics: Andrea von Berg

Düsseldorf

  • IUF – Leibniz Research Institute for Environmental Medicine: Tamara Schikowski
  • Evangelisches Krankenhaus Düsseldorf, Children‘s Hospital: Monika Gappa. 

Leipzig

  • Helmholtz Centre for Environmental Research – UFZ, Department of Environmental Immunology: Gunda Herberth

Bad Honnef

  • Medical Praxis for Children, Bad Honnef: B. Schaaf

 

  • To determine the influence of life-style factors, environmental exposures, and health-related behaviour on the development of the immune system and the incidence of allergic diseases in children.
  • To determine the influence of traffic emissions and genetics

The 25-year-follow up will start at the beginning of 2023.

 

Study region Munich

  • Helmholtz Munich – Institute of Epidemiology: Marie Standl

Wesel

  • Marien-Hospital Wesel, Department of Pediatrics: Andrea von Berg

Düsseldorf

  • IUF – Leibniz Research Institute for Environmental Medicine: Tamara Schikowski
  • Evangelisches Krankenhaus Düsseldorf, Children‘s Hospital: Monika Gappa. 

Leipzig

  • Helmholtz Centre for Environmental Research – UFZ, Department of Environmental Immunology: Gunda Herberth

Bad Honnef

  • Medical Praxis for Children, Bad Honnef: B. Schaaf

 

People at LISA

Dr. Marie Standl

Head of Research Group 'Allergic Disease Epidemiology', Head (ad interim) of Research Group 'Lung Epidemiology', Statistician View profile

Lika Palabiyik

Study Nurse

Ines Trentinaglia

Data Manager

Sarah Wagner

PhD Student

Lisa Maier

PhD Student

Carla Harris

Research Fellow

Maike Ferland

B.Sc., Data Manager

Dr. Claudia Flexeder

Postdoc, Statistician

Birgit Schmuck

Study Doctor

Elke Luxenburger

Technician

Megi Vogli

Research Fellow

Mingming Wang

PhD Student

Dr. Elisabeth Thiering

Postdoc, Statistician

Dr. Stefan Karrasch

MD, Epidemiologist

Sonja Braun

Doctoral Student

Claudia Zeller

Technical Assistant

Contacts for study participants

Claudia Zeller

Technical Assistant

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Responsible Investigator for LISA Munich

Dr. Marie Standl

Head of Research Group 'Allergic Disease Epidemiology', Head (ad interim) of Research Group 'Lung Epidemiology', Statistician

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