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All Exposomics Publications

2024 Scientific Article in Nature Communications Nat. Commun. 15:10138 (2024)

Yang, L. ; Liu, Q. ; Kumar, P. ; Sengupta, A. ; Farnoud, A. ; Shen, R. ; Trofimova, D. ; Ziegler, S. ; Davoudi, N. ; Doryab, A. ; Yildirim, A.Ö. ; Diefenbacher, M. ; Schiller, H. ; ... ; Piraud, M. ; Burgstaller, G. ; Kreyling, W.G. ; Rehberg, M. ; Stöger, T. ; Schmid, O.

LungVis 1.0: An automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages.

2024 Scientific Article in Lancet, The Lancet 403, 1027-1050 (2024)

NCD Risk Factor Collaboration (Döring, A.) ; NCD Risk Factor Collaboration (Gieger, C.) ; NCD Risk Factor Collaboration (Heier, M.) ; NCD Risk Factor Collaboration (Linkohr, B.) ; NCD Risk Factor Collaboration (Meisinger, C.) ; NCD Risk Factor Collaboration (Peters, A.) ; NCD Risk Factor Collaboration (Schneider, A.) ; NCD Risk Factor Collaboration (Stieber, J.) ; NCD Risk Factor Collaboration (Stöckl, D.) ; NCD Risk Factor Collaboration (Thorand, B.) ; NCD Risk Factor Collaboration (Wolf, K.)

Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults.

2024 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 23:199 (2024)

Harada, M. ; Adam, J. ; Covic, M. ; Ge, J. ; Brandmaier, S. ; Muschet, C. ; Huang, J. ; Han, S. ; Rommel, M. ; Rotter, M. ; Heier, M. ; Mohney, R.P. ; Krumsiek, J. ; Kastenmüller, G. ; Rathmann, W. ; Zou, Z. ; Zukunft, S. ; Scheerer, M.F. ; Neschen, S. ; Adamski, J. ; Gieger, C. ; Peters, A. ; ... ; Hrabě de Angelis, M. ; Wang-Sattler, R.

Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i.

2023 Scientific Article in Stroke Stroke 54, 810-818 (2023)

Bakker, M.K. ; Kanning, J.P. ; Abraham, G. ; Martinsen, A.E. ; ... ; HUNT All-In Stroke, CADISP group, International Consortium for Blood Pressure, International Headache Genetics Consortium, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group (Gieger, C.) ; HUNT All-In Stroke, CADISP group, International Consortium for Blood Pressure, International Headache Genetics Consortium, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group (Peters, A.)

Genetic risk Score for intracranial aneurysms: Prediction of subarachnoid hemorrhage and role in clinical heterogeneity.

2022 Scientific Article in Sleep Sleep 45:zsac098 (2022)

International EU-RLS-GENE Consortium (Schormair, B.) ; Zhao, C. ; Salminen, A.V. ; International EU-RLS-GENE Consortium (Oexle, K.) ; International EU-RLS-GENE Consortium (Winkelmann, J.) ; International EU-RLS-GENE Consortium (Oertel, W.H.) ; International EU-RLS-GENE Consortium (Gieger, C.) ; International EU-RLS-GENE Consortium (Peters, A.)

Reassessment of candidate gene studies for idiopathic restless legs syndrome in a large GWAS dataset of European ancestry.

2022 Scientific Article in Nature Genetics Nat. Genet. 54, 18–29 (2022)

Hawe, J. ; Wilson, R. ; Schmid, K. ; Zhou, L. ; Lakshmanan, L.N. ; Lehne, B.C. ; Kühnel, B. ; ... ; Baumbach, C. ; Pfeiffer, L. ; Matias-Garcia, P.R. ; Meitinger, T. ; Prokisch, H. ; Strauch, K. ; Hauck, S.M. ; Merl-Pham, J. ; Grallert, H. ; Barbosa, E.G.V. ; Peters, A. ; Kooner, J.S. ; Loh, M. ; Heinig, M. ; Gieger, C. ; Waldenberger, M. ; Chambers, J.C.

Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function.

2021 Scientific Article in Nature human behaviour Nat. Hum. Behav. 5, 1717-1730 (2021)

Mills, M.C. ; Tropf, F.C. ; Brazel, D.M. ; van Zuydam, N. ; ... ; Day, F.R. ; eQTLGen Consortium (Müller-Nurasyid, M. ; Prokisch, H. ; Schramm, K.) ; Human Reproductive Behaviour Consortium (Gieger, C.) ; Human Reproductive Behaviour Consortium (Kühnel, B.) ; Human Reproductive Behaviour Consortium (Meitinger, T.) ; Human Reproductive Behaviour Consortium (Strauch, K. ; Peters, A. ; Stöckl, D.) ; Human Reproductive Behaviour Consortium (Waldenberger, M.)

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.

2021 Scientific Article in Environmental epidemiology Environ. Epi. 5:e162 (2021)

Vlaanderen, J. ; de Hoogh, K. ; Hoek, G. ; Peters, A. ; Probst-Hensch, N. ; ... ; Vermeulen, R. ; EXPANSE Consortium (Pickford, R.) ; EXPANSE Consortium (Standl, M.) ; EXPANSE Consortium (Zhao, T.) ; EXPANSE Consortium (Schneider, A.E.) ; EXPANSE Consortium (Breitner-Busch, S.) ; EXPANSE Consortium (Wolf, K.) ; EXPANSE Consortium (Waldenberger, M.)

Developing the building blocks to elucidate the impact of the urban exposome on cardiometabolic-pulmonary disease: The EU EXPANSE project.

2021 Scientific Article in Metabolites Metabolites 11:89 (2021)

Huang, J. ; Covic, M. ; Huth, C. ; Rommel, M. ; Adam, J. ; Zukunft, S. ; Prehn, C. ; Wang, L. ; Nano, J. ; Scheerer, M.F. ; Neschen, S. ; Kastenmüller, G. ; Gieger, C. ; Laxy, M. ; Schliess, F. ; Adamski, J. ; Suhre, K. ; Hrabě de Angelis, M. ; Peters, A. ; Wang-Sattler, R.

Validation of candidate phospholipid biomarkers of chronic kidney disease in hyperglycemic individuals and their organ-specific exploration in leptin receptor-deficient db/db mouse.

2020 Scientific Article in Diabetes Diabetes 69, 2756-2765 (2020)

Huang, J. ; Huth, C. ; Covic, M. ; Troll, M. ; Adam, J. ; Zukunft, S. ; Prehn, C. ; Wang, L. ; Nano, J. ; Scheerer, M.F. ; Neschen, S. ; Kastenmüller, G. ; Suhre, K. ; Laxy, M. ; Schliess, F. ; Gieger, C. ; Adamski, J. ; Hrabě de Angelis, M. ; Peters, A. ; Wang-Sattler, R.

Machine learning approaches reveal metabolic signatures of incident chronic kidney disease in individuals with prediabetes and type 2 diabetes.

2019 Scientific Article in JAMA cardiology JAMA Cardiol. 4, 575-579 (2019)

Lamina, C. ; Kronenberg, F. ; Mack, S. ; Coassin, S. ; Rueedi, R. ; ... ; Lp(a)-GWAS-Consortium (Gieger, C.) ; Lp(a)-GWAS-Consortium (Ried, J.S.) ; Lp(a)-GWAS-Consortium (Peters, A.) ; Lp(a)-GWAS-Consortium (Meitinger, T.) ; Lp(a)-GWAS-Consortium (Strauch, K.) ; Vollenweider, P.

Estimation of the required lipoprotein(a)-lowering therapeutic effect size for reduction in coronary heart disease outcomes a mendelian randomization analysis.

In: (Internationalen Gesellschaft für Umweltepidemiologie (ISEE) und der European Respiratory Society (ERS)). 2019. accepted

Peters, A. ; Hoffmann, B. ; Brunekreef, B. ; Künzli, N. ; ... ; Schulz, H. ; Wichmann, H.-E.

Die Rolle der Luftschadstoffe für die Gesundheit.

2019 Scientific Article in Nature Genetics Nat. Genet. 51, 245-257 (2019)

Karlsson Linnér, R. ; Biroli, P. ; Kong, E. ; Meddens, S.F.W. ; ... ; eQTLGen Consortium (Prokisch, H. ; Schramm, K.) ; Social Science Genetic Association Consortium (Baumbach, C. ; Meisinger, C. ; Meitinger, T. ; Strauch, K. ; Gieger, C.) ; Beauchamp, J.P.

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

2017 Scientific Article in Neurology Neurology 89, 1829-1839 (2017)

Rannikme, K. ; Sivakumaran, V. ; Millar, H. ; Malik, R. ; ... ; SIGN study group (Gieger, C.) ; SIGN study group (Meisinger, C.) ; SIGN study group (Müller-Nurasyid, M.) ; SIGN study group (Strauch, K.) ; SIGN study group (Waldenberger, M.) ; METASTROKE Consortium (Liu, J.) ; Sudlow, C.L.M. ; SIGN study group (Peters, A.)

COL4A2 is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls.