All Exposomics Publications
In: (Internoise 2022 - 51st International Congress and Exposition on Noise Control Engineering, Glasgow, Scotland). 2022. 2999-3998
Environmental quality or behavioural cognitions? Identifying variables that can be used to classify intended civic engagement against transportation noise exposure.
In: Hydrometeorological Extreme Events and Public Health. 2022. 99-108
Conclusions and perspectives.
2022Vortrag: World Sleep 2022 Conference, 11-16 March 2022, Rom, Italien. (2022)
Longitudinal associations of insufficient sleep duration and insomnia with obesity from adolescence to young adulthood in the GINIplus and LISA studies.
2022 Scientific Article in Genome Biology Genome Biol. 23:268 (2022)
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
2022 Scientific Article in PLoS Medicine PLoS Med. 19:e1004151 (2022)
The effect of population-based blood pressure screening on long-term cardiometabolic morbidity and mortality in Germany: A regression discontinuity analysis.
2022 Scientific Article in Lipids in Health and Disease Lipids Health Dis. 21:143 (2022)
Sex-specific associations between serum lipids and hemostatic factors: The cross-sectional population-based KORA-fit study.
2022 Scientific Article in European Journal of Nutrition Eur. J. Nutr. 62, 1357-1375 (2022)
Pooled analysis of epigenome-wide association studies of food consumption in KORA, TwinsUK and LLS.
2022 Scientific Article in Life Life 12:2090 (2022)
Long-term predictors of hospitalized reinfarction after an incident acute myocardial infarction.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:1000650 (2022)
Associations of endogenous androgens and sex hormone-binding globulin with kidney function and chronic kidney disease.
2022Vortrag: Paula Rantakallio Symposium, 15-17.06.2022, Oulu, Finnland. (2022)
Allergic disease trajectories up to adolescence: Characteristics, early-life and genetic determinants .
2022Vortrag: 34th Annual Conference of the International Society for Environmental Epidemiology (ISEE 2022), 18.-21.09.2022, Athen, Griechenland. (2022)
Longitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study.
2022 Nature Communications Nat. Commun. 13:1962 (2022)
Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.
2022 Scientific Article in Nutrients Nutrients 14:4954 (2022)
Subclinical cardiovascular disease markers in relation to serum and dietary magnesium in individuals from the general population: The KORA-MRI study.
2022 Scientific Article in Nature Nature 612, 720–724 (2022)
Genetic diversity fuels gene discovery for tobacco and alcohol use.
2022 Scientific Article in Injury Injury 54, 525-532 (2022)
Lack of correlation between hip osteoarthritis and anatomical spinopelvic parameters obtained in supine position on MRI.
2022 Scientific Article in The World Journal of Biological Psychiatry World J. Biol. Psychiatry, DOI: 10.1080/15622975.2021.2014152 (2022)
Lifetime and current depression in the German National Cohort (NAKO).
2022 Scientific Article in The World Journal of Biological Psychiatry World J. Biol. Psychiatry, DOI: 10.1080/15622975.2021.2011407 (2022)
General cognitive ability assessment in the German National Cohort (NAKO) - The block-adaptive number series task.
2022 Scientific Article in The World Journal of Biological Psychiatry World J. Biol. Psychiatry, DOI: 10.1080/15622975.2021.2011408 (2022)
The assessment of cognitive function in the German National Cohort (NAKO) - Associations of demographics and psychiatric symptoms with cognitive test performance.
2022 Scientific Article in Environmental Science & Technology Environ. Sci. Technol. 56, 17815-17824 (2022)
Higher daily air temperature is associated with shorter leukocyte telomere length: KORA F3 and KORA F4.
2022 Nature Nature 612:E7 (2022)
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries.
2022 Scientific Article in Journal of Lipid Research J. Lipid Res. 63, 11:100306 (2022)
The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat.
2022 Scientific Article in Psychosomatic Medicine Psychosom. Med. 84, 1050-1055 (2022)
The association of social connectivity and body weight with the onset of type 2 diabetes: Findings from the population-based prospective MONICA/KORA cohort.
2022 Scientific Reports Sci. Rep. 12:20593 (2022)
Author Correction: Gender specific somatic symptom burden and mortality risk in the general population.
2022 Scientific Article in Genome Medicine Genome Med. 14:125 (2022)
Network reconstruction for trans acting genetic loci using multi-omics data and prior information.
2022 Scientific Article in Environment International Environ. Int. 170:107632 (2022)
Longitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study.
2022 Scientific Article in Nephrology Dialysis Transplantation Nephrol. Dial. Transplant. 38, 1240-1248 (2022)
Association between the fatty liver index and chronic kidney disease: The population-based KORA study.
2022 Scientific Article in Tomography Tomography 8, 2202-2217 (2022)
Quantification of left atrial size and function in cardiac MR in correlation to non-gated MR and cardiovascular risk factors in subjects without cardiovascular disease: A population-based cohort study.
2022 Scientific Article in Movement Disorders Mov. Disord. 37, 2110-2121 (2022)
Common variants near ZIC1 and ZIC4 in autopsy-confirmed multiple system atrophy.
2022 Other: News Item in Bayerisches Ärzteblatt Bayer. Ärztebl. 4, 164-165 (2022)
Klimaschutz ist Gesundheitsschutz.
2022 Other: Opinion in Berliner Ärzt:innen Berliner Ärzt:innen 5, 30-32 (2022)
Zeit zu handeln. Hitze ist das größte Gesundheitsrisiko durch den Klimawandel.
2022 Scientific Article in Nature Cardiovascular Research Nat. Cardio. Res. 1, 727–731 (2022)
Triggering of myocardial infarction by heat exposure is modified by medication intake.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:18733 (2022)
Automated imaging-based abdominal organ segmentation and quality control in 20,000 participants of the UK Biobank and German National Cohort Studies.
2022 Scientific Article in Life Life 12:1460 (2022)
Optimized metabotype definition based on a limited number of standard clinical parameters in the population-based KORA study.
2022 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 109, 1366-1387 (2022)
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
2022 Scientific Article in Epigenomics Epigenomics 14, 1105-1124 (2022)
Methylation status of VTRNA2-1/nc886 is stable across populations, monozygotic twin pairs and in majority of tissues.
2022 Scientific Article in Diagnostics Diagnostics 12:2356 (2022)
Long-term psychosocial consequences of whole-body magnetic resonance imaging and reporting of incidental findings in a population-based cohort study.
2022 Scientific Article in Metabolites Metabolites 12:992 (2022)
Cluster analysis statistical spectroscopy for the identification of metabolites in 1H NMR metabolomics.
2022 Scientific Article in BMC Medical Imaging BMC Med. Imaging 22:168 (2022)
AbdomenNet: Deep neural network for abdominal organ segmentation in epidemiologic imaging studies.
2022 Scientific Article in Environment International Environ. Int. 170:107581 (2022)
Long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in a large pooled European cohort: ELAPSE study.
2022 Scientific Article in Nature Communications Nat. Commun. 13:6204 (2022)
Host genetic factors related to innate immunity, environmental sensing and cellular functions are associated with human skin microbiota.
2022 Review in European Journal of Epidemiology Eur. J. Epidemiol. 37, 1107-1124 (2022)
Framework and baseline examination of the German National Cohort (NAKO).
2022 Scientific Article in Neurology Neurology 99, E1738-E1754 (2022)
Contribution of common genetic variants to risk of early onset ischemic stroke.
2022 Scientific Article in Nature Nature 611, 115-123 (2022)
Stroke genetics informs drug discovery and risk prediction across ancestries.
2022 Scientific Article in Annals of Epidemiology Ann. Epidemiol. 74, 84-96 (2022)
The bias from heaping on risk estimation: Effect of age at diagnosis of hypertension on risk of subsequent cardiovascular comorbidities.
2022 Scientific Article in Nature Communications Nat. Commun. 13:5144 (2022)
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.
2022 Scientific Article in Nature Genetics Nat. Genet. 54, 1332–1344 (2022)
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.
2022 Scientific Article in Metabolites Metabolites 12:846 (2022)
Fecal bile acids and neutral sterols are associated with latent microbial subgroups in the human gut.
2022 Scientific Article in Journal of Translational Medicine J. Transl. Med. 20:457 (2022)
Inflammatory plasma proteins predict short-term mortality in patients with an acute myocardial infarction.
2022 Scientific Article in The Lancet planetary health Lancet Planet Health 6, e784-e792 (2022)
Future temperature-related mortality considering physiological and socioeconomic adaptation: A modelling framework.
2022 Review in Environmental Pollution Environ. Pollut. 314:120245 (2022)
Short-term effects of ultrafine particles on heart rate variability: A systematic review and meta-analysis.
2022 Scientific Article in Clinical Epigenetics Clin. Epigenet. 14:114 (2022)
DNA methylation and aeroallergen sensitization: The chicken or the egg?
2022 Scientific Article in Journal of Personalized Medicine J. Pers. Med. 12:889 (2022)
Association between large arteries diameter and heart function in subjects free of cardiovascular diseases.
2022 Letter to the Editor in American Journal of Epidemiology Am. J. Epidemiol. 191, 1781–1782 (2022)
Response to AJE-00301-2022 Invited Commentary "Mechanistic and biologically based models in epidemiology; A powerful underutilized tool" by Rafael Meza & Jihyoun Jeon.
2022 Scientific Article in Sleep Sleep 45:zsac098 (2022)
Reassessment of candidate gene studies for idiopathic restless legs syndrome in a large GWAS dataset of European ancestry.
2022 Scientific Article in Clinical Nutrition Clin. Nutr. 41, 1818-1826 (2022)
Proteomics of the phase angle: Results from the population-based KORA S4 study.
2022 Scientific Article in Environmental Research Environ. Res. 215:114184 (2022)
Blood lead levels in 2018/2019 compared to 1987/1988 in the German population-based KORA study.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:15049 (2022)
Gender specific somatic symptom burden and mortality risk in the general population.
2022 Scientific Article in Nature Communications Nat. Commun. 13:5198 (2022)
Identification of risk loci for primary aldosteronism in genome-wide association studies.
2022 Scientific Article in Journal of Psychosomatic Research J. Psychosomat. Res. 162:111022 (2022)
Stability and predictors of somatic symptoms in men and women over 10 years: A real-world perspective from the prospective MONICA/KORA study.
2022 Scientific Article in Nature Communications Nat. Commun. 13:5269 (2022)
Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults.
2022 Scientific Article in Vascular Health and Risk Management Vasc. Health Risk Manag. 18, 335-346 (2022)
Association of C-terminal pro-endothelin-1 with mortality in the population-based KORA F4 study.
2022 Scientific Article in Sleep Medicine Sleep Med. 94, 26-30 (2022)
ExomeChip-based rare variant association study in restless legs syndrome.
2022 Scientific Article in Acta Diabetologica Acta Diabetol. 59, 1019-1029 (2022)
Prognostic value of stress hyperglycemia ratio on short- and long-term mortality after acute myocardial infarction.
2022 Scientific Article in Aging Aging 14, 5620-5627 (2022)
Common electrocardiogram measures are not associated with telomere length.
2022 Scientific Article in Cancers Cancers 14:3363 (2022)
Uncovering the contribution of moderate-penetrance susceptibility genes to breast cancer by whole-exome sequencing and targeted enrichment sequencing of candidate genes in women of European ancestry.
2022 Scientific Article in Life Life 12:1064 (2022)
Association between usual dietary intake of food groups and DNA methylation and effect modification by metabotype in the KORA FF4 cohort.
2022 Scientific Article in Stroke Stroke 53, 2331-2339 (2022)
A family and a genome-wide polygenic risk score are independentlyassociated with stroke in a population-based study.
2022 Scientific Article in International Journal of Behavioral Nutrition and Physical Activity Int. J. Behav. Nutr. Phys. Act. 19:102 (2022)
Association of physical activity with utilization of long-term care in community-dwelling older adults in Germany: Results from the population-based KORA-Age observational study.
2022 Review in European Respiratory Review Eur. Respir. Rev. 31:220038 (2022)
Air pollution, metabolites and respiratory health across the life-course.
2022 Scientific Article in International Journal of Obesity Int. J. Obes. 46, 1366–1374 (2022)
Effect of obesity on the associations of 25-hydroxyvitamin D with prevalent and incident distal sensorimotor polyneuropathy: Population-based KORA F4/FF4 study.
2022 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 19:47 (2022)
Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: A comparison between a traditional versus a new route-specific approach using gold nanoparticles in rats.
2022 Scientific Article in Pancreatology Pancreatol. 22, 449-456 (2022)
Colocalization analysis of pancreas eQTLs with risk loci from alcoholic and novel non-alcoholic chronic pancreatitis GWAS suggests potential disease causing mechanisms.
2022 Scientific Article in European Journal of Internal Medicine Eur. J. Intern. Med. 100, 69-76 (2022)
Association between admission ECG changes and long-term mortality in patients with an incidental myocardial infarction: Results from the KORA myocardial infarction registry.
2022 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev. 38:e3528 (2022)
Association of MRI-based adrenal gland volume and impaired glucose metabolism in a population-based cohort study.
2022 Scientific Article in Atherosclerosis Atherosclerosis 349, 151-159 (2022)
The effect of LPA Thr3888Pro on lipoprotein(a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G>A.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:10131 (2022)
Heterogeneity in coronary heart disease risk.
2022 Scientific Article in International Journal of Hygiene and Environmental Health Int. J. Hyg. Environ. Health 244:113993 (2022)
Assessment of the association of exposure to polycyclic aromatic hydrocarbons, oxidative stress, and inflammation: A cross-sectional study in Augsburg, Germany.
2022 Scientific Article in Environmental Science & Technology Environ. Sci. Technol. 56, 9277–9290 (2022)
Long-term exposure to source-specific fine particles and mortality – a pooled analysis of 14 European cohorts within the ELAPSE project.
2022 Scientific Article in Environment International Environ. Int. 166:107341 (2022)
Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort.
2022 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 21:99 (2022)
Associations of the vasoactive peptides CT-proET-1 and MR-proADM with incident type 2 diabetes: Results from the BiomarCaRE Consortium.
2022 Scientific Article in Nature Genetics Nat. Genet. 54, 560-572 (2022)
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
2022 Nature Genetics Nat. Genet. 54:735 (2022)
Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 31, 3566-3579 (2022)
Genetic and clinical determinants of abdominal aortic diameter: Genome-wide association studies, exome array data and Mendelian randomization study.
2022 Scientific Article in American Journal of Epidemiology Am. J. Epidemiol. 191, 1766–1775 (2022)
From atherosclerosis to myocardial infarction - a process-oriented model investigating the role of risk factors.
2022 Scientific Article in Environmental Pollution Environ. Pollut. 302:119071 (2022)
Short-term effects of cold spells on plasma viscosity: Results from the KORA cohort study in Augsburg, Germany.
2022 Scientific Article in JCI insight JCI insight 7:e157035 (2022)
Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases.
2022 Scientific Article in Environmental Research Environ. Res. 212:113360 (2022)
Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of U.S. adults.
2022 Scientific Article in Environmental Research Environ. Res. 212:113503 (2022)
Association of long-term environmental exposures in pregnancy and early life with islet autoimmunity development in children in Bavaria, Germany.
2022 Scientific Article in Communications Biology Comm. Biol. 5:580 (2022)
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
2022 Scientific Article in Journals of Gerontology Series A: Biological Sciences and Medical Sciences J. Gerontol. A Biol. Sci. Med. Sci. 77, 1750-1759 (2022)
The role of epigenetic clocks in explaining educational inequalities in mortality: A multi-cohort study and meta-analysis.
2022 Scientific Article in Investigative Radiology Invest. Radiol. 57, 478-487 (2022)
Whole-body magnetic resonance imaging in the large population-based German National Cohort study: Predictive capability of automated image quality assessment for protocol repetitions.
2022 Scientific Article in British Journal of Cancer BJC Br. J. Cancer 126, 1499-1507 (2022)
Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: The ELAPSE project.
2022 Scientific Article in Scandinavian Journal of Gastroenterology Scand. J. Gastroenterol. 57, 1349-1360 (2022)
Validity of fatty liver disease indices in the presence of alcohol consumption.
2022 Scientific Article in Frontiers in Cardiovascular Medicine Front. Cardiovasc. Med. 9:869395 (2022)
Undiagnosed impaired glucose tolerance and type-2 diabetes in acute myocardial infarction patients: Fequency, characteristics and long-term mortality.
2022 Scientific Article in Aging Cell Aging Cell:e13608 (2022)
Integrative analysis of clinical and epigenetic biomarkers of mortality.
2022 Scientific Article in Diabetologia Diabetologia 65, 1328-1338 (2022)
Health impact of seven herpesviruses on (pre)diabetes incidence and HbA1c: Results from the KORA cohort.
2022 Scientific Article in PLoS Computational Biology PLoS Comput. Biol. 18:e1010044 (2022)
A randomization-based causal inference framework for uncovering environmental exposure effects on human gut microbiota.
2022 Scientific Article in Atherosclerosis Atherosclerosis 352, 10-17 (2022)
Association between a polygenic and family risk score on the prevalence and incidence of myocardial infarction in the KORA-F3 study.
2022 Scientific Article in Nature Communications Nat. Commun. 13:2408 (2022)
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases.
2022 Scientific Article in PLoS ONE PLoS ONE 17:e0268815 (2022)
Genetically regulated gene expression and proteins revealed discordant effects.
2022 Scientific Article in eLife eLife 11:e71802 (2022)
Epigenetic scores for the circulating proteome as tools for disease prediction.
2022 Scientific Article in Circulation Genomic and precision medicine Circ. Genom. Precis. Med. 15:e003489 (2022)
Genome-wide characterization of a highly penetrant form of hyperlipoproteinemia associated with genetically elevated cardiovascular Risk.
2022 Editorial in Environmental Health: A Global Access Science Source Environ. Health 21:37 (2022)
Priorities for research on environment, climate and health, a European perspective.
2022 Review in Frontiers in psychiatry Front. Psychiatr. 13:815718 (2022)
Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health.
2022 Scientific Article in Nature Communications Nat. Commun. 13:1222 (2022)
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.
2022 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 119, 179–870 (2022)
Zunahme psychischer Störungen während der COVID-19-Pandemie – die Rolle beruflicher und finanzieller Belastungen. Eine Analyse der NAKO Gesundheitsstudie.
2022 Scientific Article in Diagnostics Diagnostics 12:965 (2022)
Validation of the 30-year Framingham Risk Score in a German population-based cohort.
2022 Scientific Article in Preventive medicine reports Prev. Med. Rep. 26:101700 (2022)
Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures: The MORGAM prospective cohort project.
2022 Scientific Article in BMC Geriatrics BMC Geriatr. 22:115 (2022)
Impact of prenatal and childhood adversity effects around World War II on multimorbidity: Results from the KORA-Age study.
2022 Scientific Article in Tomography Tomography 8, 560-569 (2022)
Whole-body MRI-derived adipose tissue characterization and relationship to pulmonary function impairment.
2022 Scientific Article in Psychoneuroendocrinology Psychoneuroendocrinology 141:105753 (2022)
Dysregulated diurnal cortisol patterns are associated with cardiovascular mortality: Findings from the KORA-F3 study.
2022 Scientific Article in Annals of Medicine Ann. Med. 54, 900-908 (2022)
Shock index and modified shock index are predictors of long-term mortality not only in STEMI but also in NSTEMI patients.
2022 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 10:e002558 (2022)
Association of renin and aldosterone with glucose metabolism in a Western European population: The KORA F4/FF4 study.
2022 Scientific Article in BMJ Open Ophthalmology BMJ Open Ophthalmol. 7:e000912 (2022)
Incidence, progression and risk factors of age-related macular degeneration in 35-95-year-old individuals from three jointly designed German cohort studies.
2022 Scientific Article in Nutrients Nutrients 14:797 (2022)
Association between adipose tissue depots and dyslipidemia: The KORA-MRI population-based study.
2022 Scientific Article in PLoS ONE PLoS ONE 17:e0262330 (2022)
Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study.
2022 Scientific Article in Allergy Allergy 77, 2803–2817 (2022)
Methylation risk scores for childhood aeroallergen sensitization: Results from the LISA birth cohort.
2022 Letter to the Editor in Environmental Health Perspectives Environ. Health Perspect. 130:38002 (2022)
Response to "Comment on 'Invited perspective: The NO2 and mortality dilemma solved? Almost there!'".
2022 Review in Environment International Environ. Int. 163:107202 (2022)
Setting the European environment and health research agenda –under-researched areas and solution-oriented research.
2022 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 205, 1429-1439 (2022)
Long-term air pollution exposure and pneumonia related mortality in a large pooled European cohort.
2022 Scientific Article in Nature Genetics Nat. Genet. 54, 232-239 (2022)
Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility.
2022 Nature Communications Nat. Commun. 13:1122 (2022)
Author Correction: Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis (Nature Communications, (2022), 13, 1, (143), 10.1038/s41467-021-27706-6).
2022 Scientific Article in Allergy Allergy 77, 2482-2497 (2022)
Differential effects of lung inflammation on insulin resistance in humans and mice.
2022 Scientific Article in Briefings in Bioinformatics Brief. Bioinform. 23:bbab535 (2022)
TIGER: Technical variation elimination for metabolomics data using ensemble learning architecture.
2022 Scientific Article in Nature Genetics Nat. Genet. 54, 18–29 (2022)
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function.
2022 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 13, 976-986 (2022)
Population-based cohort imaging: skeletal muscle mass by magnetic resonance imaging in correlation to bioelectrical-impedance analysis.
2022 Scientific Article in Nature Communications Nat. Commun. 13:143 (2022)
Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis.
2022 Scientific Article in The Lancet planetary health Lancet Planet Health 6, e9-e18 (2022)
Long-term exposure to low ambient air pollution concentrations and mortality among 28 million people: results from seven large European cohorts within the ELAPSE project.
2022 Scientific Article in Cytokine Cytokine 150:155786 (2022)
Association of serum uromodulin with adipokines in dependence of type 2 diabetes.
2022 Scientific Article in Translational research Transl. Res. 242, 93-104 (2022)
Novel associations between inflammation-related proteins and adiposity: A targeted proteomics approach across four population-based studies.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 31, 1171-1182 (2022)
Associations of carotid intima media thickness with gene expression in whole blood and genetically predicted gene expression across 48 tissues.
2022 Scientific Article in Nutrients Nutrients 14:132 (2022)
Association of habitual dietary intake with liver iron—a population-based imaging study.
2022 Scientific Article in Neurology Neurology 98, e1002-e1012 (2022)
Circulating interleukin-6 levels and incident ischemic stroke: A systematic review and meta-analysis of prospective studies
2022 Scientific Article in Journal of Environmental Management J. Environ. Manage. 302:114048 (2022)
Low emission zones reduced PM10 but not NO2 concentrations in Berlin and Munich, Germany.
2022 Scientific Article in Nephrology Dialysis Transplantation Nephrol. Dial. Transplant. 37, 1916-1926 (2022)
Novel biomarkers of inflammation, kidney function and chronic kidney disease in the general population.
2022 Review in Environment International Environ. Int. 158:106915 (2022)
Getting out of crises: Environmental, social-ecological and evolutionary research is needed to avoid future risks of pandemics.
2022 Scientific Article in Acta Radiologica Acta Radiol. 63, 750-759 (2022)
Association between cardiovascular risk factors and degenerative disc disease of the thoracolumbar spine in the general population: Results from the KORA MRI Study.
2022 Scientific Article in Cardiovascular Research Cardiovasc. Res. 118, 1088–1102 (2022)
Cis-epistasis at the LPA locus and risk of cardiovascular diseases.
In: Versorgungs-Report: Klima und Gesundheit. 2021. 105-117
Interaktion von Temperatur und Luftschadstoffen: Einfluss auf Morbidität und Mortalität.
2021 Letter to the Editor in Environmental Health Perspectives Environ. Health Perspect. 129, 121304 (2021)
Invited perspective: The NO2 and mortality dilemma solved? Almost there!
2021 Scientific Article in Metabolites Metabolites 11:871 (2021)
Distribution and associated factors of hepatic iron-A population-based imaging study.
2021 Scientific Article in Nature Communications Nat. Commun. 12:7174 (2021)
Meta-analyses identify DNA methylation associated with kidney function and damage.
2021 Scientific Article in Nature Communications Nat. Commun. 12:7173 (2021)
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus.
2021 Scientific Article in Nature Nature 600, 675-679 (2021)
The power of genetic diversity in genome-wide association studies of lipids.
2021 Scientific Article in BMC Health Services Research BMC Health Serv. Res. 21:1301 (2021)
Impact of investment case on equitable access to maternal and child health services in Nepal: A quasi-experimental study.
2021 Scientific Article in Cells Cells 10:3336 (2021)
Blood immunoproteasome activity is regulated by sex, age and in chronic inflammatory diseases: A first population-based study.
2021 Scientific Article in American Journal of Ophthalmology Am. J. Ophthalmol. 236, 99-106 (2021)
Physical activity, incidence and progression of age-related macular degeneration: A multi-cohort study.
2021 Scientific Article in Clinical Epigenetics Clin. Epigenet. 13:198 (2021)
Validating biomarkers and models for epigenetic inference of alcohol consumption from blood.
2021 Scientific Article in Nature Communications Nat. Commun. 12:6618 (2021)
Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.
2021 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 20:223 (2021)
Association of glycated hemoglobin A1c levels with cardiovascular outcomes in the general population: Results from the BiomarCaRE (Biomarker for Cardiovascular Risk Assessment in Europe) consortium.
2021 Scientific Article in Brain: A Journal of Neurology Brain, DOI: 10.1093/brain/awab360 (2021)
Blood DNA methylation provides an accurate biomarker of KMT2B-related dystonia and predicts onset.
2021 Scientific Article in ESC heart failure ESC Heart Fail. 8, 4584–4592 (2021)
Association of iron deficiency with incident cardiovascular diseases and mortality in the general population.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0255231 (2021)
Investment case approach for equitable access to maternal neonatal and child health services: Stakeholders' perspective in Nepal.
2021 Scientific Article in Journal of Human Hypertension J. Hum. Hypertens., DOI: 10.1038/s41371-021-00619-z (2021)
Cardiovascular mortality risk in young adults with isolated systolic hypertension: Findings from population-based MONICA/KORA cohort study.
2021 Scientific Article in Clinical Epigenetics Clin. Epigenet. 13:195 (2021)
Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: An EWAS in multi-ethnic Asian individuals.
2021 Scientific Article in Nature human behaviour Nat. Hum. Behav. 5, 1717-1730 (2021)
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:19365 (2021)
Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function.
2021 Scientific Article in Gefahrstoffe, Reinhaltung der Luft Gefahrstoffe Reinhalt. Luft 81, 353-361 (2021)
Hochaufgelöste Erfassung der urbanen Feinstaubbelastung mittels Messnetz aus kostengünstigen Sensoren und numerischen Simulationen.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 2527-2535 (2021)
Natriuretic peptides and risk of type 2 diabetes: Results from the biomarkers for cardiovascular risk assessment in Europe (BiomarCaRE) consortium.
2021 Review in International Journal of Environmental Research and Public Health Int. J. Environ. Res. Public Health 18:9856 (2021)
Sex/gender-differences in the health effects of environmental noise exposure on hypertension and ischemic heart disease— A systematic review.
2021 Scientific Article in BMJ Open Gastroenterology BMJ Open Gastroenterol. 8:e000709 (2021)
Association between hepatic fat and subclinical vascular disease burden in the general population.
2021 Scientific Article in Lancet, The Lancet 398, 957-980 (2021)
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: A pooled analysis of 1201 population-representative studies with 104 million participants.
2021 Scientific Article in BMJ BMJ 374:n1904 (2021)
Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: Pooled analysis.
2021 Scientific Article in The Lancet planetary health Lancet Planet Health 5, e620-e632 (2021)
Long-term exposure to low-level ambient air pollution and incidence of stroke and coronary heart disease: A pooled analysis of six European cohorts within the ELAPSE project.
2021 Scientific Article in Environmental epidemiology Environ. Epi. 5:e162 (2021)
Developing the building blocks to elucidate the impact of the urban exposome on cardiometabolic-pulmonary disease: The EU EXPANSE project.
2021 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 20:168 (2021)
Association of sex-specific differences in lipoprotein(a) concentrations with cardiovascular mortality in individuals with type 2 diabetes mellitus.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:16173 (2021)
Subclinical cardiac impairment relates to traditional pulmonary function test parameters and lung volume as derived from whole-body MRI in a population-based cohort study.
2021 Scientific Article in Nature Nature 596, 393-397 (2021)
Genetic insights into biological mechanisms governing human ovarian ageing.
2021 Scientific Article in Experimental Gerontology Exp. Gerontol. 153:111500 (2021)
Gender-linked determinants for utilization of long-term care in community-dwelling adults 65+ in Germany: Results from the population-based KORA-Age study.
2021 Scientific Article in Journal of Hypertension J. Hypertens. 39, 2527-2533 (2021)
N-glycosylation of immunoglobulin G predicts incident hypertension.
2021 Scientific Article in European Heart Journal Eur. Heart J. 42, 2439-2454 (2021)
SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe.
2021 Scientific Article in Frontiers in Environmental Science Front. Env. Sci. 9:624180 (2021)
The association between particulate air pollution and respiratory mortality in Beijing before, during, and after the 2008 Olympic and Paralympic Games.
2021 Scientific Article in Nutrition & metabolism Nutr. Metab. 18:73 (2021)
Dietary habits and the presence and degree of asymptomatic diverticular disease by magnetic resonance imaging in a Western population: A population-based cohort study.
2021 Scientific Article in Clinical Epigenetics Clin. Epigenet. 13:143 (2021)
Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs.
2021 Scientific Article in International Journal of Cancer Int. J. Cancer 149, 1887–1897 (2021)
Long-term exposure to air pollution and liver cancer incidence in six European cohorts.
2021 Scientific Article in Genome Biology Genome Biol. 22:194 (2021)
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging.
2021 Scientific Article in Clinical Kidney Journal Clin. Kidney J. 14, 1618-1625 (2021)
Serum uromodulin is inversely associated with biomarkers of subclinical inflammation in the population-based KORA F4 study.
2021 Nature Communications Nat. Commun. 12:4256 (2021)
Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.
2021 Scientific Article in Journal of Nutritional Science : JNS J. Nutr. Sci. 10:e46 (2021)
Prediction of type 2 diabetes mellitus based on nutrition data.
2021 Scientific Article in Cardiovascular Research Cardiovasc. Res. 118:1742–1757 (2021)
Chronically elevated branched chain amino acid levels are pro-arrhythmic.
2021 Scientific Article in Clinical Epigenetics Clin. Epigenet. 13:121 (2021)
DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function.
2021 Scientific Article in Nature Genetics Nat. Genet. 53, 840-860 (2021)
The trans-ancestral genomic architecture of glycemic traits.
2021 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 10:2751 (2021)
Chronic inflammation mediates the association between cortisol and hyperglycemia: Findings from the cross-sectional population-based KORA Age Study.
2021 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 9:e002050 (2021)
White matter hyperintensity volume in pre-diabetes, diabetes and normoglycemia.
2021 Scientific Article in European Journal of Epidemiology Eur. J. Epidemiol. 36, 1143-1155 (2021)
Meta-analysis of epigenome-wide association studies of carotid intima-media thickness.
2021 Scientific Article in BMJ Open BMJ Open 11:e046641 (2021)
Admission glucose level and short-term mortality in older patients with acute myocardial infarction: Results from the KORA Myocardial Infarction Registry.
2021 Scientific Article in Genetic Epidemiology Genet. Epidemiol. 45, 633-650 (2021)
Comparison of genetic risk prediction models to improve prediction of coronary heart disease in two large cohorts of the MONICA/KORA study.
2021 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 12, 1011–1023 (2021)
Proteomic profiling of low muscle and high fat mass: A machine learning approach in the KORA S4/FF4 study.
2021 Scientific Article in Journal of the American Society of Nephrology J. Am. Soc. Nephrol. 32, 1747-1763 (2021)
Plasma proteomics of renal function: A trans-ethnic metaanalysis and Mendelian randomization study.
2021 Scientific Article in Nature Communications Nat. Commun. 12:3987 (2021)
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.
2021 Scientific Article in Journal of Epidemiology and Community Health J. Epidemiol. Community Health 75, 1147-1154 (2021)
Roles of allostatic load, lifestyle and clinical risk factors in mediating the association between education and coronary heart disease risk in Europe.
2021 Scientific Article in International Journal of Hygiene and Environmental Health Int. J. Hyg. Environ. Health 235:113752 (2021)
Association of persistent organic pollutants with sensorimotor neuropathy in participants with and without diabetes or prediabetes: Results from the population-based KORA FF4 study.
2021 Scientific Article in Statistics in Medicine Stat. Med. 40, 3299-3312 (2021)
Simulating the dynamics of atherosclerosis to the incidence of myocardial infarction, applied to the KORA population.
2021 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 20:111 (2021)
Metabolic syndrome and the plasma proteome: From association to causation.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0252385 (2021)
Correlation between thoracolumbar disc degeneration and anatomical spinopelvic parameters in supine position on MRI.
2021 Scientific Article in Nature Communications Nat. Commun. 12:2830 (2021)
Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption.
2021 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 23, 1868–1878 (2021)
Distribution patterns of intramyocellular and extramyocellular fat by magnetic resonance imaging in subjects with diabetes, prediabetes and normoglycaemic controls.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 82-85 (2021)
Folgeerkrankungen des Diabetes mellitus.
2021 Scientific Article in International Journal of Public Health Int. J. Public Health 66:633909 (2021)
Educational level, but not income or area deprivation, is related to macrovascular disease: Results from two population-based cohorts in Germany.
2021 Scientific Article in International Journal of Environmental Research and Public Health Int. J. Environ. Res. Public Health 18:6215 (2021)
Genetic variation and cardiovascular risk factors: A cohort study on migrants from the former soviet union and a native german population.
2021 Scientific Article in Basic Research in Cardiology Basic Res. Cardiol. 116:29 (2021)
Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarction.
2021 Scientific Article in Molecular Psychiatry Mol. Psychiatry 26, 6293-6304 (2021)
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.
2021 Scientific Article in Journal of Psychosomatic Research J. Psychosomat. Res. 145:110480 (2021)
Generalized anxiety disorder symptoms and type 2 diabetes onset: Findings from the Prospective Cooperative Health Research in the Region of Augsburg F4 and FF4 studies.
2021 Scientific Article in Geographische Rundschau Geograph. Rundschau 73, 14-18 (2021)
Gesundheitsrelevanz von Luftinhaltsstoffen: Feinstaub, Stickoxide und Ozon und deren Veranderungen unterdem Klimawandel.
2021 Scientific Article in British Journal of Dermatology - BJD Br. J. Dermatol. 185, 573-584 (2021)
Host traits, lifestyle and environment are associated with the human skin bacteria.
2021 Scientific Article in Human Genetics and Genomics Advances HGG Advances 2:100013 (2021)
Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits.
2021 Scientific Article in Environmental Research Environ. Res. 198:111153 (2021)
COVID-19 and heat waves: New challenges for healthcare systems.
2021 Scientific Article in Environmental Health Perspectives Environ. Health Perspect. 129:47009 (2021)
Long-term exposure to fine particle elemental components and natural and cause-specific mortality – a pooled analysis of eight European cohorts within the ELAPSE project.
2021 Scientific Article in Hypertension Hypertension 77, 1076-1085 (2021)
Predictive importance of blood pressure characteristics with increasing age in healthy men and women: The MORGAM Project.
2021 Scientific Article in Microbiome Microbiome 9:61 (2021)
Associations between habitual diet, metabolic disease, and the gut microbiota using latent Dirichlet allocation.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:6307 (2021)
Admission ECG changes predict short term-mortality after acute myocardial infarction less reliable in patients with diabetes.
2021 Scientific Article in Clinical Epigenetics Clin. Epigenet. 13:60 (2021)
Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases.
2021 Scientific Article in eLife eLife 10:e60060 (2021)
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC).
2021 Scientific Article in Nutrients Nutrients 13:1275 (2021)
Significant impact of coffee consumption on MR-based measures of cardiac function in a population-based cohort study without manifest cardiovascular disease.
2021 Review in Cell Cell 184, 1455-1468 (2021)
Hallmarks of environmental insults.
2021 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 184, 289-298 (2021)
Serum insulin is associated with right ventricle function parameters and lung volumes in subjects free of cardiovascular disease.
2021 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 113, 639-646 (2021)
Relation of body fat mass and fat-free mass to total mortality: Results from 7 prospective cohort studies.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1279 (2021)
Revealing the role of the human blood plasma proteome in obesity using genetic drivers.
2021 Scientific Article in Value in Health Value Health 24, 274-280 (2021)
Utility decrements associated with diabetes and related complications: Estimates from a population-based study in Germany.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:2476 (2021)
Low serum calcium is associated with higher long-term mortality in myocardial infarction patients from a population-based registry.
2021 Scientific Article in Environmental Pollution Environ. Pollut. 275:116663 (2021)
Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort.
2021 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 9:e001951 (2021)
Cross-sectional and prospective relationships of endogenous progestogens and estrogens with glucose metabolism in men and women: A KORA F4/FF4 Study.
2021 Scientific Article in BMC Medicine BMC Med. 19:38 (2021)
Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study.
2021 Scientific Article in Metabolites Metabolites 11:89 (2021)
Validation of candidate phospholipid biomarkers of chronic kidney disease in hyperglycemic individuals and their organ-specific exploration in leptin receptor-deficient db/db mouse.
2021 Scientific Article in Journal of Cardiovascular Magnetic Resonance J. Cardiov. Magn. Reson. 23:2 (2021)
Association of antecedent cardiovascular risk factor levels and trajectories with cardiovascular magnetic resonance-derived cardiac function and structure.
2021 Scientific Article in Clinical Epigenetics Clin. Epigenet. 13:7 (2021)
DNA methylation and lipid metabolism: An EWAS of 226 metabolic measures.
2021 Scientific Article in PLoS Genetics PLoS Genet. 17:e1009236 (2021)
Human genome diversity data reveal that L564P is the predominant TPC2 variant and a prerequisite for the blond hair associated M484L gain-of-function effect.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:2325 (2021)
Associated factors of white matter hyperintensity volume: A machine-learning approach.
2021 Scientific Article in Clinical Kidney Journal Clin. Kidney J. 14, 205-211 (2021)
Serum uromodulin and decline of kidney function in older participants of the population-based KORA F4/FF4 study.
2021 Scientific Article in Nature Genetics Nat. Genet. 53, 147–155 (2021)
Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome.
2021 Scientific Article in Statistics in Medicine Stat. Med. 40, 1321-1335 (2021)
Assessing environmental epidemiology questions in practice with a causal inference pipeline: An investigation of the air pollution-multiple sclerosis relapses relationship.
2021 Letter to the Editor in Environmental Research Environ. Res. 193:110600 (2021)
A call for urgent action to safeguard our planet and our health in line with the helsinki declaration.
2021 Review in Environment International Environ. Int. 146:106272 (2021)
The COVID-19 pandemic and global environmental change: Emerging research needs.
2021 Scientific Article in Experimental Gerontology Exp. Gerontol. 145:111196 (2021)
Living longer but less healthy: The female disadvantage in health expectancy. Results from the KORA-Age study.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, e1647-e1659 (2021)
A panel of six biomarkers significantly improves the prediction of type 2 diabetes in the MONICA/KORA study population.
2021 Scientific Article in Environmental Research Environ. Res. 193:110568 (2021)
Long-term exposure to fine particle elemental components and lung cancer incidence in the ELAPSE pooled cohort.
2021 Scientific Article in EBioMedicine EBioMedicine 63:103151 (2021)
DNA methylation-based biomarkers of age acceleration and all-cause death, myocardial infarction, stroke, and cancer in two cohorts: The NAS, and KORA F4.
2021 Scientific Article in European Journal of Radiology Eur. J. Radiol. 134:109451 (2021)
Incidental findings in whole-body MR imaging of a population-based cohort study: Frequency, management and psychosocial consequences.
2021 Scientific Article in Environment International Environ. Int. 146:106267 (2021)
Long-term exposure to low-level air pollution and incidence of asthma: The ELAPSE project.
2021 Review in European Journal of Nutrition Eur. J. Nutr. 60, 2331–2341 (2021)
Association between dietary patterns and prediabetes, undetected diabetes or clinically diagnosed diabetes: Results from the KORA FF4 study.
2021 Scientific Article in Nutrition, Metabolism and Cardiovascular Diseases Nutr. Metab. Cardiovasc. Dis. 31, 429-438 (2021)
Reversion from prediabetes to normoglycaemia after weight change in older persons: The KORA F4/FF4 study.
2021 Scientific Article in Environment International Environ. Int. 146:106249 (2021)
Long-term low-level ambient air pollution exposure and risk of lung cancer – a pooled analysis of 7 European cohorts.
2021 Scientific Article in JAMA cardiology JAMA Cardiol. 6, 587-592 (2021)
Association of circulating monocyte chemoattractant protein-1 levels with cardiovascular mortality: A meta-analysis of population-based studies.
2021 Scientific Article in Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren Rofo-Fortschr. Rontg. 193, 33-41 (2021)
Magnetic resonance imaging of diverticular disease and its association with adipose tissue compartments and constitutional risk factors in subjects from a western general population.
2021 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev. 37:e3369 (2021)
Associations between haemoglobin A(1c)and mortality rate in the KORA S4 and the Heinz Nixdorf Recall population-based cohort studies.
2021 Scientific Article in Molecular Psychiatry Mol. Psychiatry 26, 2111–2125 (2021)
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
2020 Other: Opinion in Nature reviews. Cardiology Nat. Rev. Cardiol. 18, 1-2 (2020)
Cardiovascular risks of climate change.
2020 Scientific Article in Circulation Genomic and precision medicine Circ. Genom. Precis. Med. 13, 640-648 (2020)
Genetic predisposition to coronary artery disease in type 2 diabetes mellitus.
2020 Scientific Article in Environmental Health Perspectives Environ. Health Perspect. 128:127013 (2020)
Association of long-term air pollution with prevalence and incidence of distal sensorimotor polyneuropathy: Kora F4/FF4 study.
2020 Scientific Article in Lancet, The Lancet 396, 1511-1524 (2020)
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: A pooled analysis of 2181 population-based studies with 65 million participants.
2020 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 117, 861-867 (2020)
The impact of the COVID-19 pandemic on self-reported health.
2020 Scientific Article in BMC Public Health BMC Public Health 20:1901 (2020)
Different information needs in subgroups of people with diabetes mellitus: A latent class analysis.
2020 Scientific Article in Zeitschrift für Psychosomatische Medizin und Psychotherapie Z. Psychosom. Med. Psychother. 66, 418-424 (2020)
Von der Petrischale ins Bevölkerungslaboratorium: grenzenlose Entwicklungschancen für die Forschung zur seelischen Gesundheit. Ein Plädoyer.
2020 Scientific Article in Zeitschrift für Psychosomatische Medizin und Psychotherapie Z. Psychosom. Med. Psychother. 66, 324-336 (2020)
Seelische Gesundheit als Forschungsgegenstand in der MONICA-KORA-Studie.
2020 Scientific Article in Circulation Genomic and precision medicine Circ. Genom. Precis. Med. 13, 387-395 (2020)
Genetic determinants of electrocardiographic P-wave duration and relation to atrial fibrillation.
2020 Review in European Respiratory Review Eur. Respir. Rev. 29:200116 (2020)
Meta-analysis on short-term exposure to ambient ultrafine particles and respiratory morbidity.
2020 Other: Opinion in The Lancet planetary health Lancet Planet Health 4, e503-e505 (2020)
The Helsinki Declaration 2020: Europe that protects.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:15373 (2020)
Association of familial history of diabetes or myocardial infarction and stroke with risk of cardiovascular diseases in four German cohorts.
2020 Scientific Article in Clinical Epigenetics Clin. Epigenet. 12:157 (2020)
Smoking-related changes in DNA methylation and gene expression are associated with cardio-metabolic traits.
2020 Scientific Article in Antioxidants Antioxidants 9:908 (2020)
The association between serum bilirubin levels and colorectal cancer risk: Results from the prospective cooperative health research in the region of Augsburg (KORA) in Germany.
2020 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 19 (2020)
Associations of cardiac stress biomarkers with incident type 2 diabetes and changes in glucose metabolism: KORA F4/FF4 study.
2020 Scientific Article in Lecture Notes in Computer Science Lect. Notes Comput. Sc. 12436 LNCS, 270-280 (2020)
Bayesian neural networks for uncertainty estimation of imaging biomarkers.
2020 Scientific Article in Academic radiology Acad. Radiol. 28, 1, S1-S10 (2020)
MRI-derived radiomics features of hepatic fat predict metabolic states in individuals without cardiovascular disease.
2020 Scientific Article in Translational Psychiatry Transl. Psychiatry 10:323 (2020)
Subjective mental health, incidence of depressive symptoms in later life, and the role of epigenetics: Results from two longitudinal cohort studies.
2020 Scientific Article in Diabetes Diabetes 69, 2756-2765 (2020)
Machine learning approaches reveal metabolic signatures of incident chronic kidney disease in individuals with prediabetes and type 2 diabetes.
2020 Scientific Article in Diabetes Diabetes 69, 2766-2778 (2020)
Deciphering the plasma proteome of type 2 diabetes.
2020 Scientific Article in BMC Medicine BMC Med. 18:229 (2020)
Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses.
2020 Scientific Article in Acta Diabetologica Acta Diabetol. 57, 1481-1491 (2020)
Toward targeted prevention: Risk factors for prediabetes defined by impaired fasting glucose, impaired glucose tolerance and increased HbA1c in the population-based KORA study from Germany.
2020 Meeting abstract in The proceedings of the Nutrition Society Proc. Nutr. Soc. 79, E654-E654 (2020)
Association between dietary fat intake and MRI-determined visceral, subcutaneous, or hepatic fat in men and women from the general population.
2020 Meeting abstract in The proceedings of the Nutrition Society Proc. Nutr. Soc. 79, E380-E380 (2020)
Validation of metabotypes identified in an Irish population in the German KORA FF4 study.
2020 Scientific Article in BMC Medical Genomics BMC Med. Genomics 13:120 (2020)
Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.
2020 Scientific Article in Circulation Genomic and precision medicine Circ. Genom. Precis. Med. 13:e002766 (2020)
Whole blood DNA methylation signatures of diet are associated with cardiovascular disease risk factors and all-cause mortality.
2020 Scientific Article in Aging Aging 12, 16539-16554 (2020)
Accelerated epigenetic aging as a risk factor for chronic obstructive pulmonary disease and decreased lung function in two prospective cohort studies.
2020 Scientific Article in Stroke Stroke 51, 2770-2777 (2020)
Cardiac Troponin I and incident stroke in European cohorts: Insights from the BiomarCaRE project,
2020 Scientific Article in Genome Medicine Genome Med. 12:74 (2020)
Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein(a) in 10,910 individuals.
2020 Scientific Article in Cell Host & Microbe Cell Host Microbe 28, 258-272.e6 (2020)
Arrhythmic gut microbiome signatures predict risk of type 2 diabetes.
2020 Scientific Article in Aging Aging 12, 14092-14124 (2020)
Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals.
2020 Scientific Article in GeroScience GeroScience 42, 1365–1376 (2020)
Seropositivity for pathogens associated with chronic infections is a risk factor for all-cause mortality in the elderly: findings from the Memory and Morbidity in Augsburg Elderly (MEMO) Study.
2020 Scientific Article in Economics and Human Biology Econ. Hum. Biol. 38:100893 (2020)
The effect of retirement on biomedical and behavioral risk factors for cardiovascular and metabolic disease.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:9610 (2020)
Diverging trends in age at first myocardial infarction: Evidence from two German population-based studies.
2020 Scientific Article in Nature Nature 582, 73-77 (2020)
Repositioning of the global epicentre of non-optimal cholesterol.
2020 Scientific Article in Nutrients Nutrients 12:1684 (2020)
Association of dietary patterns and type-2 diabetes mellitus in metabolically homogeneous subgroups in the KORA FF4 study.
2020 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 8:e001425 (2020)
Proinsulin to insulin ratio is associated with incident type 2 diabetes but not with vascular complications in the KORA F4/FF4 study.
2020 Scientific Article in Spine Journal Spine J. 20, 1386-1396 (2020)
Long-term effect of physical inactivity on thoracic and lumbar disc degeneration-an MRI-based analysis of 385 individuals from the general population.
2020 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 17:21 (2020)
Quantitative biokinetics over a 28 day period of freshly generated, pristine, 20 nm silver nanoparticle aerosols in healthy adult rats after a single 11/2-hour inhalation exposure.
2020 Scientific Article in Nutrients Nutrients 12:1527 (2020)
Vertebral bone marrow fat is independently associated to vat but not to sat: Kora FF4—whole-body mr imaging in a population-based cohort.
2020 Scientific Article in Nature Communications Nat. Commun. 11:2542 (2020)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:8363 (2020)
Machine-learning based exploration of determinants of gray matter volume in the KORA-MRI study.
2020 Scientific Article in Hypertension Hypertension 75, 1420-1428 (2020)
Does estimated pulse wave velocity add prognostic information? MORGAM prospective cohort project.
2020 Scientific Article in Health science reports Health Sci. Rep. 3:e157 (2020)
Association between unrealistic comparative optimism and self-management in individuals with type 2 diabetes: Results from a cross-sectional, population-based study.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0232073 (2020)
A genome-wide analysis of DNA methylation identifies a novel association signal for Lp(a) concentrations in the LPA promoter.
2020 Scientific Article in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 63, 301-311 (2020)
Physical activity in the German National Cohort (NAKO): Use of multiple assessment tools and initial results.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0231974 (2020)
Seropositivity of selected chronic infections and different measures of obesity.
2020 Scientific Article in Endocrine Connections Endocr. Connect. 9, 326–336 (2020)
Sex hormone-binding globulin, androgens and mortality: The KORA-F4 cohort study.
2020 Scientific Article in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 63, 312-321 (2020)
Messung der körperlichen Fitness in der NAKO Gesundheitsstudie – Methoden, Qualitätssicherung und erste deskriptive Ergebnisse.
2020 Scientific Article in Microorganisms Microorganisms 8:547 (2020)
Investigation of adiposity measures and operational taxonomic unit (OTU) data transformation procedures in stool samples from a German Cohort Study using machine learning algorithms.
2020 Scientific Article in Molecular Nutrition and Food Research Mol. Nutr. Food Res. 64:1900918 (2020)
Evaluation of the metabotype concept identified in an Irish population in the German KORA cohort study.
2020 Scientific Article in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 63, 267-278 (2020)
Soziodemografische und erwerbsbezogene Merkmale in der NAKO Gesundheitsstudie.
2020 Review in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 63, 426-438 (2020)
Design und Qualitätskontrolle der zahnmedizinischen Untersuchung in der NAKO Gesundheitsstudie.
2020 Scientific Article in Acta Diabetologica Acta Diabetol. 57, 1057-1063 (2020)
Longitudinal association of type 2 diabetes and insulin therapy with muscle parameters in the KORA-Age study.
2020 Scientific Article in Cancer Prevention Research Cancer Prev. Res. 13, 377-384 (2020)
Epidemiologic risk factors in a comparison of a Barrett Esophagus Registry (BarrettNET) and a case-control population in Germany.
2020 Scientific Article in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 63, 439-451 (2020)
Erfassung selbst berichteter kardiovaskulärer und metabolischer Erkrankungen in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse.
2020 Scientific Article in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 63, 290-300 (2020)
Anthropometrische Messungen in der NAKO Gesundheitsstudie – mehr als nur Größe und Gewicht.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0230185 (2020)
Association between metabolic syndrome and hip osteoarthritis in middle-aged men and women from the general population.
2020 Scientific Article in European Heart Journal Eur. Heart J. 41, 3949–3959 (2020)
The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development.
2020 Scientific Article in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 63, 415-425 (2020)
Häufigkeiten muskuloskelettaler Symptome und Erkrankungen in der bevölkerungsbezogenen NAKO Gesundheitsstudie.
2020 Scientific Article in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 63, 254-266 (2020)
Die Basiserhebung der NAKO Gesundheitsstudie: Teilnahme anden Untersuchungsmodulen, Qualitätssicherung und Nutzungvon Sekundärdaten.
2020 Scientific Article in European Radiology Eur. Radiol. 30, 3417-3428 (2020)
Bone marrow fat fraction assessment in regard to physical activity: KORA FF4-3-T MR imaging in a population-based cohort.
2020 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 19:32 (2020)
Biomarker-defined pathways for incident type 2 diabetes and coronary heart disease-a comparison in the MONICA/KORA study.
2020 Scientific Article in PLoS Computational Biology PLoS Comput. Biol. 16:e1007616 (2020)
DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.
2020 Scientific Article in Atherosclerosis Atherosclerosis 297, 1-7 (2020)
Serum uromodulin and risk for cardiovascular morbidity and mortality in the community-based KORA F4 study.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0216635 (2020)
Renal and renal sinus fat volumes as quantified by magnetic resonance imaging in subjects with prediabetes, diabetes, and normal glucose tolerance.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:774 (2020)
Factors associated with habitual time spent in different physical activity intensities using multiday accelerometry.
2020 Review in Maturitas : The European Menopause Journal Maturitas 135, 6-26 (2020)
Sexually dimorphic DNA-methylation in cardiometabolic health: A systematic review.
2020 Scientific Article in Diabetic Medicine Diabetic Med. 37, 1737-1741 (2020)
Anxiety boosts progression of prediabetes to type 2 diabetes: Findings from the prospective Cooperative Health Research in the Region of Augsburg F4 and FF4 studies.
2020 Scientific Article in Preventive Medicine Prev. Med. 133:106025 (2020)
The times we are born into and our lifestyle choices determine our health trajectories in older age - Results from the KORA(1)-Age study.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0227648 (2020)
Impact of long-term storage and freeze-thawing on eight circulating microRNAs in plasma samples.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:442 (2020)
Association of serum uric acid with visceral, subcutaneous and hepatic fat quantified by magnetic resonance imaging.
2020 Scientific Article in Nature Communications Nat. Commun. 11:15 (2020)
Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits.
2020 Scientific Article in Atherosclerosis Atherosclerosis 296, 32-39 (2020)
Risk for cardiovascular events responds nonlinearly to carotid intima-media thickness in the KORA F4 study.
2020 Scientific Article in The journal of allergy and clinical immunology J. Allergy Clin. Immunol. 145, 1208-1218 (2020)
Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression.
2020 Scientific Article in International Journal of Epidemiology Int. J. Epidemiol. 49, 173-192 (2020)
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: A pooled analysis of 458 population-based studies in Asian and Western countries.
2020 Scientific Article in Quality of Life Research Qual. Life Res. 29, 391-401 (2020)
Resilience is strongly associated with health-related quality of life but does not buffer work-related stress in employed persons 1 year after acute myocardial infarction.
2020 Scientific Article in Public Health Nutrition Public Health Nutr. 23, 446-456 (2020)
Malnutrition and related risk factors in older adults from different health-care settings: an enable study.
2019 Review in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 116, 881-886 (2019)
The effects of fine dust, ozone, and nitrogen dioxide on health.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:18616 (2019)
Association of smoking and physical inactivity with MRI derived changes in cardiac function and structure in cardiovascular healthy subjects.
2019 Scientific Article in Frontiers in Pharmacology Front. Pharmacol. 10:1293 (2019)
Unpredictable nanoparticle retention in commonly used plastic syringes introduces dosage uncertainties that may compromise the accuracy of nanomedicine and nanotoxicology studies.
2019 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 18:145 (2019)
Glucose and insulin levels are associated with arterial stiffness and concentric remodeling of the heart.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:16972 (2019)
Association of longitudinal risk profile trajectory clusters with adipose tissue depots measured by magnetic resonance imaging.
2019 Scientific Article in International Journal of Environmental Research and Public Health Int. J. Environ. Res. Public Health 16:4247 (2019)
Change in physical activity after diagnosis of diabetes or hypertension: Results from an observational population-based cohort study.
2019 Meeting abstract in Multiple Sclerosis Journal Mult. Scler. J. 25, 906-907 (2019)
Identification of functionally relevant genetic variants associated with multiple sclerosis using deep learning.
2019 Other: Opinion in European Heart Journal Eur. Heart J. 40, 3440-3441 (2019)
Burden of myocardial infarctions attributable to heat and cold.
2019 Scientific Article in Circulation Research Circ. Res. 125, 773-782 (2019)
Circulating monocyte chemoattractant protein-1 and risk of stroke meta-analysis of population-based studies involving 17 180 individuals.
2019 Scientific Article in Nature Genetics Nat. Genet. 51, 1459-1474 (2019)
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
2019 Scientific Article in Nature Communications Nat. Commun. 10:4130 (2019)
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
2019 Scientific Article in European Journal of Epidemiology Eur. J. Epidemiol. 34, 1055-1074 (2019)
Validated inference of smoking habits from blood with a finite DNA methylation marker set.
2019 Scientific Article in Circulation Circulation 140, 645-657 (2019)
Blood leukocyte DNA methylation predicts risk of future myocardial infarction and coronary heart disease: A longitudinal study of 11,461 participants from population-based cohorts.
2019 Scientific Article in Nature Communications Nat. Commun. 10:3346 (2019)
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals.
2019 Meeting abstract in Atherosclerosis Atherosclerosis 287, E58-E58 (2019)
A comprehensive map of the variability in the lipoprotein (A) KIV 2 repeat region and follow-up of the KIV-2 ARG20TER mutation in 11,000 individuals.
2019 Scientific Article in Health Economics Review Health Econ. Rev. 9:26 (2019)
Are health risk attitude and general risk attitude associated with healthcare utilization, costs and working ability? Results from the German KORA FF4 cohort study.
2019 Letter to the Editor in Gesundheitswesen, Das Gesundheitswesen 81, 444-447 (2019)
Kritik an Population Attributable Fraction bei genauerem Hinsehen nicht gerechtfertigt.
2019 Scientific Article in PharmacoEconomics Pharmacoeconomics 37, 1485-1494 (2019)
Performance of the UKPDS outcomes model 2 for predicting death and cardiovascular events in patients with type 2 diabetes mellitus from a German Population-Based Cohort.
2019 Scientific Article in Experimental Gerontology Exp. Gerontol. 124:110644 (2019)
Exposure to anticholinergic and sedative medications using the Drug Burden Index and its association with vertigo, dizziness and balance problems in older people - Results from the KORA-FF4 Study.
2019 Scientific Article in Atherosclerosis Atherosclerosis 288, 1-8 (2019)
Associations between fecal bile acids, neutral sterols, and serum lipids in the KORA FF4 study.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:9693 (2019)
Visceral adiposity index (VAI), lipid accumulation product (LAP), and product of triglycerides and glucose (TyG) to discriminate prediabetes and diabetes.
2019 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 16:29 (2019)
Quantitative biokinetics over a 28day period of freshly generated, pristine, 20 nm titanium dioxide nanoparticle aerosols in healthy adult rats after a single two-hour inhalation exposure.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:9439 (2019)
Genome-wide association study of change in fasting glucose over time in 13,807 non-diabetic European Ancestry Individuals.
2019 Scientific Article in JAMA cardiology JAMA Cardiol. 4, 575-579 (2019)
Estimation of the required lipoprotein(a)-lowering therapeutic effect size for reduction in coronary heart disease outcomes a mendelian randomization analysis.
2019 Particle and Fibre Toxicology Part. Fibre Toxicol. 16:26 (2019)
Particle toxicology and health - where are we? (vol 16, 19, 2019).
2019 Meeting abstract in Journal of Psychosomatic Research J. Psychosomat. Res. 121, 134-134 (2019)
Higher oxytocin levels associated with a history of suicidal ideation in old age: Findings from the population based KORA Age Study.
2019 Other: Opinion in Lancet Respiratory Medicine, The Lancet Resp. Med. 7, 650-652 (2019)
Promoting clean air: Combating fake news and denial.
2019 Scientific Article in Environment International Environ. Int. 132:104723 (2019)
Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation.
2019 Scientific Article in Journal of the American College of Cardiology J. Am. Coll. Cardiol. 73, 3118-3131 (2019)
Effects of calcium, magnesium, and potassium concentrations on ventricular repolarization in unselected individuals.
2019 Meeting abstract in Journal of Psychosomatic Research J. Psychosomat. Res. 121, 125-126 (2019)
Chronic inflammation contributes to cortisol-induced hyperglycemia: Findings from the KORA Age study.
2019 Meeting abstract in Journal of Psychosomatic Research J. Psychosomat. Res. 121, 124-124 (2019)
Inverse relationship between social isolation and type 2 diabetes incidence in people with obesity: Findings from the MONICA/KORA prospective cohort.
2019 Scientific Article in European Radiology Eur. Radiol. 29, 6662-6670 (2019)
Hepatic fat is superior to BMI, visceral and pancreatic fat as a potential risk biomarker for neurodegenerative disease.
2019 Scientific Article in Nature Genetics Nat. Genet. 51, 957-972 (2019)
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
2019 Scientific Article in PLoS ONE PLoS ONE 14:e0216110 (2019)
Dynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants.
2019 Scientific Article in Journal of Neurology J. Neurol. 266, 2120-2128 (2019)
Vertigo and dizziness cause considerable more health care resource use and costs: Results from the KORA FF4 study.
2019 Scientific Article in Nutrients Nutrients 11:1151 (2019)
Isocaloric substitution of dietary carbohydrate intake with fat intake and MRI-determined total volumes of visceral, subcutaneous and hepatic fat content in middle-aged adults.
2019 Scientific Article in Nature Nature 569, 260-264 (2019)
Rising rural body-mass index is the main driver of the global obesity epidemic in adults.
2019 Scientific Article in PLoS ONE PLoS ONE 14:e0216222 (2019)
Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease.
2019 Scientific Article in Frontiers in Public Health Front. Publ. Health 7:96 (2019)
Helicobacter pylori seropositivity: Prevalence, associations, and the impact on incident metabolic diseases/risk factors in the population-based KORA study.
2019 Scientific Article in American Journal of Epidemiology Am. J. Epidemiol. 188, 1033-1054 (2019)
Multiancestry genome-wide association study of lipid levels incorporating gene-alcohol interactions.
2019 Scientific Article in International Archives of Allergy and Immunology Int. Arch. Allergy Immunol. 179, 262-272 (2019)
Different psychosocial factors are associated with seasonal and perennial allergies in adults: Cross-sectional results of the KORA FF4 study.
2019 Review in Particle and Fibre Toxicology Part. Fibre Toxicol. 16:19 (2019)
Particle toxicology and health - where are we?
2019 Scientific Article in Aging Aging 11, 2045-2070 (2019)
Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: A multi-cohort analysis.
2019 Scientific Article in Nature Genetics Nat. Genet. 51, 636-648 (2019)
Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
2019 Scientific Article in Journal of the American College of Cardiology J. Am. Coll. Cardiol. 73, 58-66 (2019)
Association of the PHACTR1/EDN1 genetic locus with spontaneous coronary artery dissection.
2019 Scientific Article in European Journal of Epidemiology Eur. J. Epidemiol. 34, 675-687 (2019)
Being born in the aftermath of World War II increases the risk for health deficit accumulation in older age: Results from the KORA-Age study.
2019 Scientific Article in British Journal of Radiology, The Br. J. Radiol. 92:20180562 (2019)
MRI-based assessment and characterization of epicardial and paracardial fat depots in the context of impaired glucose metabolism and subclinical left-ventricular alterations.
In: (Internationalen Gesellschaft für Umweltepidemiologie (ISEE) und der European Respiratory Society (ERS)). 2019. accepted
Die Rolle der Luftschadstoffe für die Gesundheit.
2019 Meeting abstract in Experimental Dermatology Exp. Dermatol. 28, E46-E46 (2019)
Exome-wide association study reveals DOK2 as novel atopic dermatitis susceptibility gene harbouring low frequency risk variants.
2019 Scientific Article in Human Genetics Hum. Genet. 138, 375–388 (2019)
The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus.
2019 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 104, 3192-3202 (2019)
Impaired glucose metabolism in primary aldosteronism is associated with cortisol cosecretion.
2019 Scientific Article in Metabolites Metabolites 9:44 (2019)
Ageing investigation using two-time-point metabolomics data from KORA and CARLA studies.
2019 Scientific Article in European Heart Journal Eur. Heart J. 40, 1600-1608 (2019)
Temporal variations in the triggering of myocardial infarction by air temperature in Augsburg, Germany, 1987-2014.
2019 Scientific Article in Nature Genetics Nat. Genet. 51, 414-430 (2019)
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
2019 Scientific Article in Science of the Total Environment, The Sci. Total Environ. 666, 672-679 (2019)
The impact of ambient particulate matter on hospital outpatient visits for respiratory and circulatory system disease in an urban Chinese population.
2019 Scientific Article in European Journal of Public Health Eur. J. Public Health 29, 992-997 (2019)
Status quo bias and health behavior: Findings from a cross-sectional study.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:1946 (2019)
Ambient and controlled exposures to particulate air pollution and acute changes in heart rate variability and repolarization.
2019 Scientific Article in Nature Genetics Nat. Genet. 51, 245-257 (2019)
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
2019 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 109, 276-287 (2019)
Disentangling the genetics of lean mass.
2019 Scientific Article in European Journal of Human Genetics Eur. J. Hum. Genet. 27, 952-962 (2019)
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.
2019 Scientific Article in Nature Communications Nat. Commun. 10:431 (2019)
Shared heritability and functional enrichment across six solid cancers.
2019 Scientific Article in Diabetes Care Diabetes Care 42, E18-E20:DC181473 (2019)
Incidence rates of type 2 diabetes in people with impaired fasting glucose (ADA vs. WHO Criteria) and impaired glucose tolerance: Results from an older population (KORA S4/F4/FF4 Study).
2019 Scientific Article in Journal of Epidemiology and Community Health J. Epidemiol. Community Health 73, 19-25 (2019)
Temporal trends in cardiovascular risk factors and performance of the Framingham Risk Score and the Pooled Cohort Equations.
2019 Scientific Article in European Radiology Eur. Radiol. 29, 1094-1103 (2019)
Characteristics and associated risk factors of diverticular disease assessed by magnetic resonance imaging in subjects from a Western general population.
2018 Scientific Article in Neurology Genetics Neurol. Genet. 4:e293 (2018)
Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes.
2018 Meeting abstract in Blood Blood 132 (2018)
Sorafenib as maintenance therapy post allogeneic stem cell transplantation for FLT3-ITD positive AML: Results from the randomized, double-blind, placebo-controlled multicentre sormain trial.
2018 Scientific Article in Clinical Epigenetics Clin. Epigenet. 10:161 (2018)
Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction.
2018 Scientific Article in BMC Cardiovascular Disorders BMC Cardiovasc. Disord. 18:235 (2018)
Association of sleep disturbances within 4 weeks prior to incident acute myocardial infarction and long-term survival in male and female patients: An observational study from the MONICA/KORA Myocardial Infarction Registry.
2018 Scientific Article in Lecture Notes in Computer Science Lect. Notes Comput. Sc. 11167 LNCS, 223-231 (2018)
Deep shape analysis on abdominal organs for diabetes prediction.
2018 Scientific Article in EBioMedicine EBioMedicine 38, 206-216 (2018)
Association of maternal prenatal smoking GFI1-locus and cardiometabolic phenotypes in 18,212 adults.
2018 Scientific Article in Nature Genetics Nat. Genet. 50, 1505-1513 (2018)
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.
2018 Scientific Article in Nature Genetics Nat. Genet. 50, 1514-1523 (2018)
Genetics of blood lipids among similar to 300,000 multi-ethnic participants of the Million Veteran Program.
2018 Scientific Article in Nature Communications Nat. Commun. 9:4455 (2018)
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
2018 Scientific Article in Epigenetics Epigenetics 13, 1039-1055 (2018)
Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: An epigenome-wide study in the NAS and KORA cohorts.
2018 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 108, 453-475 (2018)
Body mass index is negatively associated with telomere length: A collaborative cross-sectional meta-analysis of 87 observational studies.
2018 Scientific Article in Nature Communications Nat. Commun. 9:3738 (2018)
Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation.
2018 Scientific Article in Molecular Nutrition and Food Research Mol. Nutr. Food Res. 62:1800117 (2018)
Identification of comprehensive metabotypes associated with cardiometabolic diseases in the population-based KORA study.
2018 Scientific Article in Atherosclerosis Atherosclerosis 276, 140-147 (2018)
Ldlr-/- and ApoE-/- mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease.
2018 Scientific Article in BMC Cardiovascular Disorders BMC Cardiovasc. Disord. 18:162 (2018)
Association of glycemic status and segmental left ventricular wall thickness in subjects without prior cardiovascular disease: A cross-sectional study.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:11981 (2018)
Time trends in stroke incidence and in prevalence of risk factors in Southern Germany, 1989 to 2008/09.
2018 Scientific Article in Blood Blood 132, 1842-1850 (2018)
DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis.
2018 Scientific Article in European Journal of Radiology Eur. J. Radiol. 105, 261-268 (2018)
Assessment of the degree of abdominal myosteatosis by magnetic resonance imaging in subjects with diabetes, prediabetes and healthy controls from the general population.
2018 Scientific Article in Journal of Hypertension J. Hypertens. 36, 1555-1562 (2018)
Correlation of MRI-derived adipose tissue measurements and anthropometric markers with prevalent hypertension in the community.
2018 Scientific Article in British Journal of Radiology, The Br. J. Radiol. 3:20180019 (2018)
Inter- and intra-observer variability of an anatomical landmark-based, manual segmentation method by MRI for the assessment of skeletal muscle fat content and area in subjects from the general population.
2018 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 17, 88:88 (2018)
Association between abdominal adiposity and subclinical measures of left-ventricular remodeling in diabetics, prediabetics and normal controls without history of cardiovascular disease as measured by magnetic resonance imaging: Results from the KORA-FF4 Study.
2018 Scientific Article in European Radiology Eur. Radiol. 28, 3105-3113 (2018)
Subclinical changes in MRI-determined right ventricular volumes and function in subjects with prediabetes and diabetes.
2018 Scientific Article in Investigative Radiology Invest. Radiol. 53, 357-364 (2018)
Phenotypic multiorgan involvement of subclinical disease as quantified by magnetic resonance imaging in subjects with prediabetes, diabetes, and normal glucose tolerance.
2018 Scientific Article in British Journal of Radiology, The Br. J. Radiol. 91 (2018)
The role of visceral and subcutaneous adipose tissue measurements and their ratio by magnetic resonance imaging in subjects with prediabetes, diabetes and healthy controls from a general population without cardiovascular disease.
2018 Scientific Article in PLoS ONE PLoS ONE 13:e0192448 (2018)
Alcohol consumption, but not smoking is associated with higher MR-derived liver fat in an asymptomatic study population.
2018 Scientific Article in Environmental Health Perspectives Environ. Health Perspect. 126:027004 (2018)
Long-term air pollution exposure, genome-wide DNA methylation and lung function in the lifelines cohort study.
2018 Scientific Article in Nature Genetics Nat. Genet. 50, 26-41 (2018)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
2018 Scientific Article in European heart journal - cardiovascular imaging Eur. Heart J. Cardiovasc. Imaging 19, 701-708 (2018)
Myocardial tissue characterization by contrast-enhanced cardiac magnetic resonance imaging in subjects with prediabetes, diabetes, and normal controls with preserved ejection fraction from the general population.
2018 Scientific Article in Gut (eGut) Gut 67, 1855–186 (2018)
Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.
2018 Scientific Article in Scandinavian journal of medicine & science in sports Scand. J. Med. Sci. Sports 28, 604-612 (2018)
Physical activity, muscular strength, and polypharmacy among older multimorbid persons: Results from the KORA-Age study.
2017 Scientific Article in European Journal of Human Genetics Eur. J. Hum. Genet. 25, 137-146 (2017)
Across-cohort QC analyses of GWAS summary statistics from complex traits.
2017 Scientific Article in Lancet, The Lancet 390, 2627-2642 (2017)
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 1722–1730 (2017)
Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 1758-1766 (2017)
Exome-wide association study of plasma lipids in >300,000 individuals.
2017 Scientific Article in Biopreservation and Biobanking Biopreserv. Biobank. 15, 512-518 (2017)
Influence of storage and inter- and Intra-assay variability on the measurement of inflammatory biomarkers in population-based biobanking.
2017 Scientific Article in Neurology Neurology 89, 1829-1839 (2017)
COL4A2 is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls.
2017 Scientific Article in Journal of Epidemiology and Community Health J. Epidemiol. Community Health 71, 1210-1216 (2017)
Determinants of social inequalities in stroke incidence across Europe: A collaborative analysis of 126 635 individuals from 48 cohort studies.
2017 Scientific Article in Lancet Neurology, The Lancet Neurol. 16, 898–907 (2017)
Identification of novel risk loci for restless legs syndrome: A meta-analysis of genome-wide association studies in individuals of European ancestry: A meta-analysis.
2017 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 26, 4301-4313 (2017)
Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.
2017 Scientific Article in Diabetologia Diabetologia 61, 117-129 (2017)
Metabolite ratios as potential biomarkers for type 2 diabetes: A DIRECT study.
2017 Scientific Article in Environment International Environ. Int. 108, 127-136 (2017)
DNA methylation and exposure to ambient air pollution in two prospective cohorts.
2017 Scientific Article in Archives of Toxicology Arch. Toxicol. 91, 3011–3037 (2017)
Toxic effects and biodistribution of ultrasmall gold nanoparticles.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 1113-1119 (2017)
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
2017 Scientific Article in Circulation Circulation 135, 2336-2353 (2017)
Loss of cardioprotective effects at the ADAMTS7 locus as a result of gene-smoking interactions.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 946-952 (2017)
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 834-841 (2017)
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
2017 Scientific Article in Journal of Proteome Research J. Proteome Res. 16, 2547-2559 (2017)
Plasma and serum metabolite association networks: Comparibility within and between studies using NMR and MS profiling.
2017 Scientific Article in European Heart Journal Eur. Heart J. 38, 983-990 (2017)
Long-term exposure to ambient air pollution and traffic noise and incident hypertension in seven cohorts of the European study of cohorts for air pollution effects (ESCAPE).
2017 Scientific Article in Current environmental health reports Curr. Environ. Health Rep. 4, 21-29 (2017)
Thermal control, weather, and aging.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 403-415 (2017)
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
2016 Scientific Article in Human Heredity Hum. Hered. 82, 103-139 (2016)
Estimation of trait-model parameters in a MOD score linkage analysis.
2016 Scientific Article in Research Report (Health Effects Institute) Res. Rep. Health Eff. Inst. 186, 5-75 (2016)