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Exploring the dynamics of chromatin structure and function across physiological states
© Helmholtz Zentrum München/ Daphne Cabianca

Boost for Epigenetic Research at Helmholtz Zentrum München

Awards & Grants, IES,

The German research foundation DFG funds the collaborative research center ‘Chromatin Dynamics’ (SFB 1064) for four more years. Helmholtz Zentrum München, Ludwigs-Maximilians-Universität München, Technical University of Munich and the Max Planck Institute of Biochemistry join forces for continued discoveries on the dynamics of the chromatin structure and function across physiological states.

The dynamic nature of chromatin is essential for genome integrity and is required for development, environmental adaptation and metabolic (stress) memory. Dysregulation of chromatin can lead to harmful pathological outcomes such as cancer, cardiovascular disease, or environmentally triggered disorders, such as diabetes. Thus, identifying chromatin patterns and their role in the integration of environmental inputs will be a key pillar supporting the mission of Helmholtz Zentrum München to discover solutions for the prevention and therapy of environmentally triggered diseases.

Since 2013, this collaborative research center (CRC) has united the outstanding research expertise in epigenetics of the four Munich based partners. During the new third phase (from 2021 until 2025) the CRC ‘Chromatin Dynamics’ aims to deliver a comprehensive understanding of the epigenetic processes and chromatin marks underlying the chromatin landscape using different model organisms.

The new projects funded include three projects from the Institute for Epigenetics and Stem Cells, three from the Institute of Functional Epigenetics, as well as one from the group ‘<link>Metabolic Reprogramming</link>’ of Henriette Uhlenhaut.

More details about the projects: <link epigeneticshmgu/news-events/news/news/article/49705/index.html - extern></link>