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Helmholtz Munich | Maria Keller

CRISPR dCAS9 Based Epigenetic Editing in vitro

CRISPR dCAS9 Based Epigenetic Editing in vitro

Based on previous findings for obesity specific methylation pattern in human subcutaneous- and omental visceral adipose tissue (e.g. Keller et al, 2016, Mol Met), this project aims to identify possible epigenetic alterations that define a "point of no return" in obesity and comorbidities development. Thus, we are testing the reversibility of methylation remodeling in (human) adipocytes by means of epigenetic editing.

 

Contact Project Leader

Dr. Maria Keller

PostDoc

Leipzig