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The Contribution of Salivary Extra-Cellular Vesicles to Taste-Cell Gene Expression Signatures and Eating Behavior in People with Obesity

 

The Contribution of Salivary Extra-Cellular Vesicles to Taste-Cell Gene Expression Signatures and Eating Behavior in People with Obesity

 

People living with obesity have altered taste sensitivity and eating behavior, along with impaired saliva production and oral health. This project focuses on small particles detected in saliva. These extracellular vesicles (EVs) contain regulatory factors, which may influence the function of the taste epithelium. The project aims to uncover alterations in the type and composition of EVs in relation to body weight and weight loss. We test the hypothesis that certain components of EVs play a role in taste cell function and eating behavior. With this project, we will better understand how obesity affects our sense of taste and how taste mediated food choices might be rearranged in the future in order to prevent and treat obesity.

Scientists working in the project

Dr. Kerstin Rohde-Zimmermann

PostDoc

Kristin Röhrborn

PhD Student (EKFS funded)

Contact Project Leader

Dr. Kerstin Rohde-Zimmermann

PostDoc

Leipzig