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Helmholtz Munich | Matthias Tunger Photodesign

Priv.-Doz. Dr. rer. nat. Simon Blank

Principal Investigator at Institute of Allergy Research – Molecular & Translational Allergology
+49 89 3187 2625Email meBuilding/Room: 57/107

“Our work focuses on developing novel approaches for effective allergen-specific immunotherapy to combat the burden of allergic disease and on the identification and characterization of allergens for advanced allergy diagnostics.”

“Our work focuses on developing novel approaches for effective allergen-specific immunotherapy to combat the burden of allergic disease and on the identification and characterization of allergens for advanced allergy diagnostics.”

Academic Pathway & Research Area

Simon Blank studied biology with a focus on biochemistry and molecular biology at the University of Hamburg. He obtained the degree of Dr. rer nat. in 2009 at the Department of Chemistry of the University of Hamburg where he focused on the investigation of allergic molecules and their use in diagnostics and therapy of insect venom allergy in the lab of. Prof. Dr. Reinhard Bredehorst. Afterward, Simon had the chance to work independently as a postdoc doc in the field of antibody-allergen-interactions at the Institute of Biochemistry and Molecular Biology in the context of the young researchers initiative of the University of Hamburg for the promotion of highly-qualified young scientists. In addition, during his time at the University of Hamburg, Simon was involved in university spin-offs that developed new concepts for allergen-specific immunotherapy and made novel component-resolved diagnostics for insect venom allergy available for the clinic. In 2013, he joined the Institute of Allergy Research at Helmholtz Munich, where he became the principal investigator of the Molecular & Translational Allergology group. In 2017, Simon obtained the qualification for teaching in higher education (Habilitation) in Experimental Medicine at the Faculty of Medicine of the Technical University of Munich.

The Blank lab combines recombinant allergens with the analysis of immunological tolerance in humans as well as in various models of experimental allergen-specific immunotherapy. The group aims to gain new insights into the mechanisms of immunotherapy and the allergen-immune system interaction. An important topic of the group is to translate the knowledge gained into new immunomodulatory and adjuvant approaches, new biomarkers, and the further improvement of diagnostics and to bring these new concepts directly into the clinic.

Fields of Work and Expertise

Allergen-Specific Immunotherapy Allergy Diagnostics Recombinant Allergens Immunological ToleranceHymenoptera Venom Allergy Experimental Immunotherapy Immunomodulation mRNA-based Immunotherapy Vaccines

Professional Background

2017

Habilitation in “Experimental Medicine” at the Faculty of Medicine, Technical University of Munich

Since 2013

Principal Investigator Molecular & Translational Allergology Group at Helmholtz Munich

2010-2013

Postdoctoral Research Fellow at Institute of Biochemistry and Molecular Biology, University of Hamburg

2010-2013

Lab Head at the PLS-Design GmbH, Hamburg

2005-2009

Ph.D. student, Department of Chemistry, University of Hamburg

Honors and Awards

  • Since 2022
    Board member of the Interest Group Allergy Diagnosis & Systems Medicine of the European Academy of Allergy and Clinical Immunology (EAACI)

  • Since 2020
    Associate Editor at Frontiers in Allergy and Toxins

  • Since 2017
    Member of the Immunology & Inflammation Initiative of the Helmholtz Association

  • 2012
    Independent senior researcher in the context of the young researchers initiative of the University of Hamburg for the promotion of highly-qualified young scientists

Publications

Read more

2022 Scientific Article in Frontiers in Immunology

Kreft, L. ; Schepers, A. ; Hils, M. ; Swiontek, K. ; Flatley, A. ; Janowski, R. ; Mirzaei, M.K. ; Dittmar, M. ; Chakrapani, N. ; Desai, M.S. ; Eyerich, S. ; Deng, L. ; Niessing, D. ; Fischer, K. ; Feederle, R. ; Blank, S. ; Schmidt-Weber, C.B. ; Hilger, C. ; Biedermann, T. ; Ohnmacht, C.

A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria.

Media Highlights

Recent results from the Blank Lab

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