About our Research
Our team performs research in the area of molecular medicine with a focus on innate effector mechanisms of allergy, asthma and helminth infection.
Our team is particularly interested in uncovering the roles of eicosanoid lipid mediators and macrophages in type 2 immune responses in asthma, nasal polyposis and helminth infection. A particular focus is the identification and characterization of helminth molecules that regulate type 2 inflammatory diseases. As a second major aim, the team studies innate memory responses as a mechanism of chronic airway diseases. Ultimately, our team’s research is aimed at contributing to new therapeutic strategies to treat chronic airway inflammation.
PhD student
PhD student
PhD student
Publications
Wasserer, S. ; Seiringer, P. ; Kurzen, N. ; Jargosch, M. ; Eigemann, J. ; Aydin, G. ; Raunegger, T. ; Schmidt-Weber, C.B. ; Eyerich, S. ; Biedermann, T. ; Eyerich, K. ; Lauffer, F.
TYK2 inhibition improves clinical and molecular hallmarks in various subtypes of cutaneous lupus.Jargosch, M. ; Kuruvila, J. ; Scala, E. ; Grosch, J. ; Eigemann, J. ; Wasserer, S. ; Lekiashvili, S. ; Trautwein, N. ; Kowalewski, D.J. ; Böhner, A. ; Köseoglu, Y. ; Hillig, C. ; Thomas, J. ; Lauffer, F. ; Schmidt-Weber, C.B. ; Menden, M.P. ; Walz, J.S. ; Kaesler, S. ; Eyerich, S. ; Blank, S. ; Rammensee, H.G. ; Biedermann, T. ; Eyerich, K. ; Kurgyis, Z. ; Freudenmann, L.K. ; Garzorz-Stark, N.
Immunopeptidome analysis reveals SERPINB3 as an autoantigen driving eczematized psoriasis.Kurzen, N. ; Mubarak, M. ; Eigemann, J. ; Seiringer, P. ; Wasserer, S. ; Hillig, C. ; Menden, M.P. ; Biedermann, T. ; Schmidt-Weber, C.B. ; Eyerich, K. ; Jargosch, M. ; Eyerich, S. ; Lauffer, F.
Death-associated protein kinase 1 dampens keratinocyte necroptosis and expression of genes in lichen planus.Contact