Computational Health Center

Institute of Computational Biology

The Institute of Computational Biology (ICB) develops models and methods for data analysis in systems biology and systems medicine. We integrate information on multiple scales, ranging from single-cell time series to cohort omics data. Heterogeneities in the data are modeled using statistical and dynamical approaches, both on the cellular and the population level.

The Institute of Computational Biology (ICB) develops models and methods for data analysis in systems biology and systems medicine. We integrate information on multiple scales, ranging from single-cell time series to cohort omics data. Heterogeneities in the data are modeled using statistical and dynamical approaches, both on the cellular and the population level.

Keyvisual ICB

About us

We develop innovative methods and tools in

  • data sciences
  • dynamical modeling
  • integrative omics and
  • bioimage informatics

and apply them collaboratively with our experimental partners to

  • modeling stem cell decisions
  • modeling transcriptional heterogeneities and
  • Quantifying gene-environment effects in diabetes and lung disease

to jointly advance our understanding and treatment of human diseases.

Our Groups

Computational Epigenomics

Colomé-Tatché Group

Biostatistics

Fuchs Group

Computational Molecular Medicine

Gagneur Group

Data-driven Computational Modelling

Hasenauer Group

Genetic and Epigenetic Gene Regulation

Heinig Group

Computation and Machine Learning

Jüstel Group

Systems Metabolomics

Kastenmüller Group

Medical Genomics

Knauer-Arloth Group

Computational RNA Biology

Marsico Group

Computational Biomedicine

Menden Group

Computational Statistics and Data Science for Biological Systems

C.L. Müller Group

Dynamical Inference

Schneider Lab

Translational Immunoinformatics

Schubert Group

Physics and data-based modelling of cellular decision making

Scialdone Group

Machine Learning

Theis Lab

Our News

See all
12.07.2023, Neuherberg: Helmholtz Pioneer Campus Opening. Foto: Matthias Balk/Helmholtz Zentrum München

Stem Cells, IES, Computational Health, ICB, Bioengineering, IBMI, Pioneer Campus,

Three Helmholtz Munich Researchers Elected to Bavarian Academy

At its most recent plenary session, the Bavarian Academy of Sciences and Humanities (BAdW) elected 13 distinguished scholars as new members. Among them are three researchers from Helmholtz Munich: Prof. Maria-Elena Torres-Padilla, Prof. Fabian Theis,…

Fabian Theis bei Eröffnung des Google AI Centers Berlin

AI, Awards & Grants, Computational Health, ICB,

Google Opens AI Center in Berlin and Supports AI Projects by Fabian Theis

On March 5, Google opened its first German AI Center in Berlin. The event was attended by representatives from politics, business, and science, including Federal Research Minister Dorothee Bär, Federal Digital Minister Karsten Wildberger, Berlin's…

Kidney Picture AI-Generated

AI, Transfer, Computational Health, ICB,

Helmholtz Munich Launches Collaboration on AI-Driven Kidney Disease Research

Helmholtz Munich and Novartis Biomedical Research are launching a four-year collaboration to advance kidney disease research. Starting in early 2026, the partnership will work to develop an integrated, cross-species “kidney disease atlas” at…

Big data technology data science analysis

AI, New Research Findings, Computational Health, ICB,

BioPathNet: New AI Uncovers Hidden Patterns in Biomedical Knowledge Graphs

A new artificial intelligence (AI) method called BioPathNet helps researchers systematically search large biological data networks for hidden connections – from gene functions and disease mechanisms to potential therapeutic approaches. BioPathNet was…

Detailed view of a computer interface used by geneticists showing a complex genome mapping software with colorful DNA strands without displaying any personal identity in a modern research lab

AI, New Research Findings, Computational Health, ICB,

Pertpy: A Software Toolbox Reveals How Individual Cells Respond to Therapies

With single-cell technologies, researchers can measure millions of cells in parallel and track how each one responds to specific perturbations – targeted interventions such as drug treatments, changes in gene activity or disease-like conditions.…

Icon, Computational Health, Featured Publication

Featured Publication, Computational Health, ICB,

Mapping Carotid Artery Plaques at Single-Cell Resolution

Researchers from Helmholtz Munich, the Technical University of Munich (TUM), and international partner institutions have generated one of the most detailed cellular maps of carotid artery plaques to date. Their work shows how different cell types and…

Operations & Scientific Management

Scientists at ICB

Frau Sacher, Anna, Dr._freigestellt
Dr. Anna Sacher

Head of Science Management & Administration, Institute of Computational Biology

Dr. Julia Schlehe

Munich School for Data Sciences

Daniela Herrmann

Administrative assistant

Karina Kahl

Administrative assistant

Mara Kieke

Administration and Recruitment

Sabine Kunz

Executive Assistant to Fabian Theis

Contact

Frau Sacher, Anna, Dr._freigestellt
Dr. Anna Sacher

Head of Science Management & Administration, Institute of Computational Biology

Ingolstädter Landstraße 1, 85764 Neuherberg

Building / Room: 58a, 105