All IDC Publications
As of February 9, 2023
In: Molecular Exercise Physiology. 2022. 25 S. ( ; 11)
Altitude, temperature, circadian rhythms and exercise.
2022 Scientific Article in Cell Cell 185, 5040-5058.e19 (2022)
Spatial proteomics in three-dimensional intact specimens.
2022 Scientific Article in Cancers Cancers 14:5481 (2022)
Combined targeting of pathogenetic mechanisms in pancreatic neuroendocrine tumors elicits synergistic antitumor effects.
2022 Scientific Article in Nature Communications Nat. Commun. 13:6754 (2022)
Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.
2022 Review in Cancer and Metastasis Reviews Cancer Metastasis Rev. 41, 517–547 (2022)
Obesity and cancer-extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases.
2022 Editorial in Frontiers in Pharmacology Front. Pharmacol. 13:975812 (2022)
Editorial: Ion channels and transporters in diabetes and metabolic diseases.
2022 Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 19:62 (2022)
Author Correction: Endosomal trafficking in metabolic homeostasis and diseases (Nature Reviews Endocrinology, (2022), 10.1038/s41574-022-00737-9).
2022 Review in Antioxidants Antioxidants 11:1541 (2022)
The prognostic value of derivatives-reactive oxygen metabolites (d-ROMs) for cardiovascular disease events and mortality: A review.
2022 Scientific Article in Toxicology Letters Toxicol. Lett. 368, 33-46 (2022)
In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 64:101556 (2022)
Tryptophan metabolism is a physiological integrator regulating circadian rhythms.
2022 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 357-358 (2022)
Hunger metabolism - from molecular basis to therapeutic use Werner Creutzfeldt prize 2022-a brief overview of the award winner Stephan Herzig.
2022 Editorial in Molecular Metabolism Mol. Metab. 63:101547 (2022)
10 years of molecular metabolism.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1071-1083 (2022)
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
2022 Scientific Article in Science Advances Sci. Adv. 8:eabo5555 (2022)
TSC22D4 interacts with Akt1 to regulate glucose metabolism.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 1824-1842.e9 (2022)
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
2022 Scientific Article in Advanced science Adv. Sci. 9:e2104291 (2022)
Trip13 depletion in liver cancer induces a lipogenic response contributing to plin2-dependent mitotic cell death.
2022 Review in Advances in Experimental Medicine and Biology Adv. Exp. Med. Biol. 1390, 61-82 (2022)
Nuclear receptors in energy metabolism.
Methods in Molecular Biology In: Circadian Regulation. 2022. 311-327 (Methods Mol. Biol. ; 2482)
Untargeted and targeted circadian metabolomics using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and flow injection-electrospray ionization-tandem mass spectrometry (FIA-ESI-MS/MS).
2022 Scientific Article in Life Sciences Life Sci. 303:120601 (2022)
Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain.
2022 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 29, 285-306 (2022)
Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 60:101487 (2022)
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, 2167-2181 (2022)
Six-month periodic fasting in patients with type 2 diabetes and diabetic nephropathy: A proof-of-concept study.
2022 Scientific Article in Biochemical and Biophysical Research Communications Biochem. Biophys. Res. Commun. 618, 46-53 (2022)
TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells.
2022 Scientific Article in Metabolites Metabolites 12:99 (2022)
Analogues of natural chalcones as efficient inhibitors of AKR1C3.
2022 Scientific Article in Metabolites Metabolites 12:445 (2022)
Effects of acute and chronic resistance exercise on the skeletal muscle metabolome.
2022 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14364 (2022)
Angpt2/Tie2 autostimulatory loop controls tumorigenesis.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 473-486.e9 (2022)
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
2022 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 10, 221-230 (2022)
Sexual dimorphism in COVID-19: Potential clinical and public health implications.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 329-345.e8 (2022)
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 56:101412 (2022)
Adipocyte-specific tribbles pseudokinase 1 regulates plasma adiponectin and plasma lipids in mice.
2022 Scientific Article in Cancers Cancers 14:90 (2022)
Aging aggravates cachexia in tumor-bearing mice.
2022 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 28, 1038-1052 (2022)
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.
2022 Diabetologia Diabetologia 65:257 (2022)
Correction to: Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy.
In: Endocrine Surgery Comprehensive Board Exam Guide. 2021. 935–950
Multiple endocrine neoplasia type 4 (MEN 4).
In: Gigantism and Acromegaly. 2021. 157-172
CDKN1B (p27) defects leading to pituitary tumors.
Endocrinology In: Polyendocrine Disorders and Endocrine Neoplastic Syndromes. 2021. 245-274 (Endocrinology)
Multiple endocrine neoplasia-type 4 (MEN4) and other MEN1-like syndromes.
2021 Review in Frontiers in Endocrinology Front. Endocrin. 12:765201 (2021)
Diabetic pneumopathy-a new diabetes-associated complication: Mechanisms, consequences and treatment considerations.
2021 Review in EJNMMI Research EJNMMI Res. 11:121 (2021)
Imaging pheochromocytoma in small animals: Preclinical models to improve diagnosis and treatment.
2021 Scientific Article in Cell Reports Medicine Cell Rep. Med. 2:100434 (2021)
Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
2021 Review in EJNMMI Research EJNMMI Res. 11:94 (2021)
Imaging modalities for diagnosis and monitoring of cancer cachexia.
2021 Scientific Article in STAR Protocols STAR Protoc. 2:100805 (2021)
Purification of GFP-tagged nuclei from frozen livers of INTACT mice for RNA- and ATAC-sequencing.
2021 Scientific Article in Cancers Cancers 13:4433 (2021)
Mri‐determined psoas muscle fat infiltration correlates with severity of weight loss during cancer cachexia.
2021 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-021-05557-6 (2021)
Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabi7828 (2021)
Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202101037 (2021)
RNA sequencing reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes.
2021 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle, DOI: 10.1002/jcsm.12758 (2021)
Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy.
2021 Scientific Article in Nature Communications Nat. Commun. 12:5068 (2021)
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
2021 Nature Communications Nat. Commun. 12:4796 (2021)
Author Correction: Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:7958 (2021)
Common muscle metabolic signatures highlight arginine and lysine metabolism as potential therapeutic targets to combat unhealthy aging.
2021 Review in Advanced science Adv. Sci., e2100275 (2021)
Emerging targets in type 2 diabetes and diabetic complications.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 1685-1700.e9 (2021)
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.
2021 Journal of Nutritional Biochemistry, The J. Nutr. Biochem. 97:108807 (2021)
Corrigendum to "Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance" [The Journal of Nutritional Biochemistry 57 (2018) 189-196].
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:722790 (2021)
Editorial: Stem cells in endocrine tumors.
2021 Scientific Article in Cancers Cancers 13:3097 (2021)
Gender-specific efficacy revealed by head-to-head comparison of pasireotide and octreotide in a representative in vivo model of nonfunctioning pituitary tumors.
2021 Editorial in Molecular Metabolism Mol. Metab. 50:101274 (2021)
NAFLD - A rising metabolic disease.
2021 Scientific Article in Cancers Cancers 13:2843 (2021)
Elevated expression of the rage variant-v in sclc mitigates the effect of chemotherapeutic drugs.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 82-85 (2021)
Folgeerkrankungen des Diabetes mellitus.
2021 Scientific Article in Nature Communications Nat. Commun. 12:2999 (2021)
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.
2021 Scientific Article in Diabetologia Diabetologia 64, 1850-1865 (2021)
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
2021 Scientific Article in Comprehensive Physiology Compr. Physiol. 11, 1759-1783 (2021)
Glucagon's metabolic action in health and disease.
2021 Scientific Article in Thrombosis and Haemostasis Thromb. Haemost. 121, 1464-1475 (2021)
Methylglyoxal drives a distinct, nonclassical macrophage activation status.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 49:101181 (2021)
Spatiotemporal GLP-1 and GIPR receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists.
2021 Scientific Article in Cancers Cancers 13:126 (2021)
Mutation of the cell cycle regulator p27kip1 drives pseudohypoxic pheochromocytoma development.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 394–409 (2021)
Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes.
2021 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 9:641410 (2021)
TBL1XR1 ensures balanced neural development through NCOR complex-mediated regulation of the MAPK pathway.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000898 (2021)
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 833-844.e5 (2021)
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e12461 (2021)
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism.
2020Vortrag: ASCB/EMBO Cell Bio Vitrual, 07.-12.12.2020, online. (2020)
Endosomal sorting complex protein Vps37a regulates hepatic glucose production via regulating glucagon receptor trafficking.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S384-S385 (2020)
Urinary cathepsin levels are predictive of the improvement of albuminuria and are associated with elevated excretion of free glucosepane.
2020 Molecular Metabolism Mol. Metab. 41:101068 (2020)
Molecular regulation of urea cycle function by the liver glucocorticoid receptor (vol 4, pg 732, 2015).
2020 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 11, 1459-1475 (2020)
High levels of modified ceramides are a defining feature of murine and human cancer cachexia.
2020 Review in Current opinion in pharmacology Curr. Opin. Pharmacol. 53, 101-116 (2020)
Exploiting common aspects of obesity and cancer cachexia for future therapeutic strategies.
2020 Scientific Article in International Journal of Cancer Int. J. Cancer 147, 3523-3538 (2020)
miR-34a is upregulated in AIP-mutated somatotropinomas and promotes octreotide resistance.
2020 Scientific Article in Liver International Liver Int. 40, 2982-2997 (2020)
High-protein diet more effectively reduces hepatic fat than low-protein diet despite lower autophagy and FGF21 levels.
2020 Other: Opinion in Cell Metabolism Cell Metab. 32, 331-333 (2020)
An antibody attack against body wasting in cancer.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 40:101026 (2020)
STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue.
2020 Scientific Article in Journal of Diabetes and its Complications J. Diab. Complic. 34:107648 (2020)
Urinary cathepsin L is predictive of changes in albuminuria and correlates with glucosepane in patients with type 2 diabetes in a closed-cohort study.
2020 Review in Seminars in cell & developmental biology Semin. Cell Dev. Biol. 108, 72-81 (2020)
Hepatic lipid droplet homeostasis and fatty liver disease.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 36:100953 (2020)
De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry.
2020 Scientific Article in Nature Communications Nat. Commun. 11:2306 (2020)
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
2020 Scientific Article in Acta Physiologica Acta Physiol. 230:e13496 (2020)
Exercise-dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF-SRF signalling.
2020 Review in Cell Cell 181, 1189-1193 (2020)
Biomedical research goes viral: Dangers and opportunities.
2020 Scientific Article in EMBO Journal, The EMBO J. 39:e103477 (2020)
Compromised DNA repair is responsible for diabetes-associated fibrosis.
2020 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 12:e09271 (2020)
Endothelial Notch signaling controls insulin transport in muscle.
2020 Scientific Article in Nature Biotechnology Nat. Biotechnol. 38, 293-296 (2020)
Label-free metabolic imaging by mid-infrared optoacoustic microscopy in living cells.
2019 Meeting abstract in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle, 1387 (2019)
Exploring the contribution of the liver to cancer cachexia development.
2019 Scientific Article in Nature Communications Nat. Commun. 10:5686 (2019)
Glucose homeostasis is regulated by pancreatic beta-cell cilia via endosomal EphA-processing.
2019 Scientific Article in Molecular Cell Mol. Cell 76, 531-545.e5 (2019)
Cistromic reprogramming of the diurnal glucocorticoid hormone response by high-fat diet.
2019 Scientific Article in Nature metabolism Nat. Metab. 1, 1009-1026 (2019)
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
2019 Scientific Article in EMBO Reports EMBO Rep. 20:e48552 (2019)
The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 28, 91-106 (2019)
alpha-Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles.
2019 Review in Molecular Aspects of Medicine Mol. Aspects Med. 68, 90-100 (2019)
The role of brown and beige adipose tissue in glycaemic control.
2019 Scientific Article in Archives of Toxicology Arch. Toxicol. 93, 1609-1637 (2019)
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
2019 Scientific Article in Nature Communications Nat. Commun. 10:2474 (2019)
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic beta-cells.
2019 Review in Traffic Traffic 20, 552-570 (2019)
Metabolic regulation through the endosomal system.
Handbook of Experimental Pharmacology In: Brown Adipose Tissue. 2019. (Handb. Exp. Pharmacol. ; 251)
Preface.
2019 Review in Thrombosis and Haemostasis Thromb. Haemost. 119, 567-575 (2019)
Endocannabinoid signalling in atherosclerosis and related metabolic complications.
2019 Scientific Article in Endocrine Connections Endocr. Connect. 8, 367–377 (2019)
Aip-mutated acromegaly resistant to first-generation somatostatin analogs: Long-term control with pasireotide lar in two patients.
2019 Review in EMBO Reports EMBO Rep. 20:e47258 (2019)
Energy metabolism in cachexia.
2019 Scientific Article in Cellular Signalling Cell. Signal. 57, 45-57 (2019)
Chemical genetic screen identifies Gapex-5/GAPVDI and STBD1 as novel AMPK substrates.
2019 Scientific Article in FASEB Journal FASEB J. 33, 5924-5941 (2019)
A miR-29a-driven negative feedback loop regulates peripheral glucocorticoid receptor signaling.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 19, 97-106 (2019)
Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis.
2019 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 127, 203-214 (2019)
Effects of the reactive metabolite methylglyoxal on cellular signalling, insulin action and metabolism – What we know in mammals and what we can learn from yeast.
2018 Diabetes Diabetes 67, 343-344 (2018)
Erratum. Adipocyte glucocorticoid Receptor deficiency attenuates aging- and HFD-induced obesity and impairs the feeding-fasting transition. Diabetes 2017;66:272-286.
2018 Scientific Article in BMC Genomics BMC Genomics 19:794 (2018)
Norepinephrine triggers an immediate-early regulatory network response in primary human white adipocytes.
2018 Review in Trends in cancer Trends Cancer 4, 849-860 (2018)
Cancer cachexia: More than skeletal muscle wasting.
2018 Scientific Article in Developmental Cell Dev. Cell 47, 205-221.e7 (2018)
Organellar proteomics and phospho-proteomics reveal subcellular teorganization in diet-induced hepatic steatosis.
2018 Scientific Article in World Journal of Gastroenterology World J. Gastroenterol. 24, 4028-4035 (2018)
Adiponectin affects the mechanical responses in strips from the mouse gastric fundus.
2018 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 17, 2358-2370 (2018)
Comparative secretome analyses of primary murine white and brown adipocytes reveal novel adipokines.
2018 Scientific Article in Cell Cell 174, 1571-1585.e11 (2018)
Atlas of circadian metabolism reveals system-wide coordination and communication between clocks.
2018 Scientific Article in PLoS Biology PLoS Biol. 16:e2005886 (2018)
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.
2018 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 10:e8613 (2018)
Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors.
2018 Scientific Article in Science Signaling Sci. Signal. 11:eaai7838 (2018)
Jak-TGF beta cross-talk links transient adipose tissue inflammation to beige adipogenesis.
2018 Scientific Article in Journal of Nutritional Biochemistry, The J. Nutr. Biochem. 57, 189-196 (2018)
Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance.
2018 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 293, 4845-4859 (2018)
High-glucose toxicity is mediated by AICAR-transformylase/ IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans.
2018 Scientific Article in Circulation Circulation 137, 2592-2608 (2018)
Inhibition of endothelial notch signaling impairs fatty acid transport and leads to metabolic and vascular remodeling of the adult heart.
2018 Review in Current Opinion in Clinical Nutrition & Metabolic Care Curr. Opin. Clin. Nutr. Metab. Care 21, 164-167 (2018)
Skeletal muscle mass is controlled by the MRF4-MEF2 axis.
2018 Scientific Article in Nature medicine Nat. Med. 24, 62-72 (2018)
A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.
2018 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 25, 145-162 (2018)
Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: A novel model of invasive medullary thyroid carcinoma.
2017 Meeting abstract in Acta clinica Belgica Acta Clin. Belg. 72, 16-17 (2017)
Long-term management of resistant acromegaly with pasireotide LAR in 2 cases with a familial AIP mutation.
2017 Meeting abstract in Molecular Biology of the Cell Mol. Biol. Cell 28 (2017)
Proteomics identifies organelle specific phosphorylation and reveals major subcellular reorganization in the progression of NAFLD.
2017 Scientific Article in Frontiers in Physiology Front. Physiol. 8:968 (2017)
Comparative analysis of muscle hypertrophy models reveals divergent gene transcription profiles and points to translational regulation of muscle growth through increased mTOR signaling.
2017 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 45, 10595-10613 (2017)
Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.
2017 Scientific Article in Cell Metabolism Cell Metab. 26, 1–14.e1–e5 (2017)
Acetyl-CoA carboxylase 1-dependent protein acetylation controls breast cancer metastasis and recurrence.
2017 Review in Hormone molecular biology and clinical investigation Horm. Mol. Biol. Clin. Investig. 31:0043 (2017)
Endocrine and autocrine/paracrine modulators of brown adipose tissue mass and activity as novel therapeutic strategies against obesity and type 2 diabetes.
2017 Meeting abstract in Diabetologia Diabetologia 60, S507-S508 (2017)
Loss of glyoxalase 1 in various mammalian cells is associated with an increased resistance against environmental stressors.
2017 Scientific Article in Redox Biology Redox Biol. 13, 674-686 (2017)
Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux.
2017 Review in Frontiers in Neuroscience Front. Neurosci. 11:369 (2017)
Circadian metabolomics in time and space.
2017 Scientific Article in Cell Reports Cell Rep. 20, 1422-1434 (2017)
A hepatic GAbp-AMPK axis links inflammatory signaling to systemic vascular damage.
2017 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 24, T161-T177 (2017)
Animal models of MEN1.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 873-881 (2017)
Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution.
2017 Review in EMBO Journal, The EMBO J. 36, 1999-2017 (2017)
Adipose tissue: Between the extremes.
2017 Other: News Item in EMBO Reports EMBO Rep. 18, 1039-1040 (2017)
Let's burn whatever you have: Mitofusin 2 metabolically re-wires brown adipose tissue.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:4023 (2017)
Acute loss of the hepatic endo-lysosomal system in vivo causes compensatory changes in iron homeostasis.
2017 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 18:984 (2017)
Dicarbonyls and advanced glycation end-products in the development of diabetic complications and targets for intervention.
2017 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, 5265-5270 (2017)
Lsd1 prevents age-programed loss of beige adipocytes.
2017 Scientific Article in Journal of Diabetes and its Complications J. Diab. Complic. 31, 1058-1065 (2017)
ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy.
2017 Scientific Article in Nature medicine Nat. Med. 23, 623-630 (2017)
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis.
2017 Scientific Article in Experimental Cell Research Exp. Cell Res. 350, 242-252 (2017)
Functional properties of hepatocytes in vitro are correlated with cell polarity maintenance.
2017 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 24, 1-15 (2017)
Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo.
2017 Scientific Article in Journal of Diabetes and its Complications J. Diab. Complic. 31, 304-310 (2017)
Reduction in ins-7 gene expression in non-neuronal cells of high glucose exposed Caenorhabditis elegans protects from reactive metabolites, preserves neuronal structure and head motility, and prolongs lifespan.
2017 Scientific Article in Journal of Magnetic Resonance Imaging J. Magn. Reson. Imaging 45, 369-380 (2017)
In vivo assessment of cold stimulation effects on the fat fraction of brown adipose tissue using DIXON MRI.
2017 Scientific Article in Endocrine Endocrine 55, 386-397 (2017)
Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas.
2016 Meeting abstract in Diabetologia Diabetologia 59, S521-S521 (2016)
Impaired lung function as a diabetes related complication.
2016 Meeting abstract in Diabetologia Diabetologia 59, S234-S234 (2016)
Transforming growth factor beta-like stimulated clone 22 D4 promotes diabetic hyperglycaemia and insulin resistance.
2016 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 292, 3224-3238 (2016)
Loss of glyoxalase 1 induces compensatory mechanism to achieve dicarbonyl detoxification in mammalian Schwann cells.
2016 Scientific Article in Recent Results in Cancer Research Recent Results Cancer Res. 208, 219-242 (2016)
Biological mechanisms for the effect of obesity on cancer risk: Experimental evidence.
2016 Scientific Article in Nature Communications Nat. Commun. 7:13267 (2016)
Control of diabetic hyperglycaemia and insulin resistance through TSC22D4.
2016 Meeting abstract in Neuroendocrinology Neuroendocrinology 103, 8-8 (2016)
The Role of p27 in Pheochromocytoma Development.
2016 Review in Skeletal muscle Skelet. Muscle 6:33 (2016)
The functional significance of the skeletal muscle clock: Lessons from Bmal1 knockout models.
2016 Scientific Article in Diabetes Diabetes 66, 272-286:db160381 (2016)
Adipocyte glucocorticoid receptor deficiency attenuates aging and HFDinduced obesity, and impairs the feedingfasting transition.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 615-25 (2016)
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function.
2016 Scientific Article in BioTechniques / Protocol Guide BioTechniques 61, 137-148 (2016)
Characterization of aggregate load and pattern in living yeast cells by flow cytometry.
2016 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 126, 3263-3278 (2016)
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
2016 Scientific Article in Journal of natural medicines J. Nat. Med. 22, 1120-1130 (2016)
An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice.
2016 Scientific Article in Nature Communications Nat. Commun. 7:12397 (2016)
MRF4 negatively regulates adult skeletal muscle growth by repressing MEF2 activity.
2016 Letter to the Editor in Journal of Physiology - Paris J. Physiol. 594, 3161-3162 (2016)
Inactivation of the intrinsic muscle clock does not cause sarcopenia.
2016 Scientific Article in Nature Communications Nat. Commun. 7:11869 (2016)
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.
2016 Scientific Article in Thyroid Thyroid 26, 1131-1140 (2016)
Primary cell culture systems for human thyroid studies.
2016 Scientific Article in Endocrinology Endocrinology 157, 3157-3166 (2016)
Morphology, biochemistry and pathophysiology of MENX-related pheochromocytoma recapitulate the clinical features.
2016 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 8, 654-669 (2016)
Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health.
2016 Scientific Article in Science Signaling Sci. Signal. 9:rs1 (2016)
Mouse redox histology using genetically encoded probes.
2016 Scientific Article in Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids Biochim. Biophys. Acta-Mol. Cell Biol. Lipids 1861, 285-293 (2016)
IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 67-78 (2016)
Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.
2015 Scientific Article in Endocrine Endocrine 51, 236-244 (2015)
Aggressive tumor growth and clinical evolution in a patient with X-linked acro-gigantism syndrome.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 406-417 (2015)
Mice lacking neutral amino acid transporter B0AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control.
2015 Scientific Article in Journal of Diabetes Research J. Diabetes Res.:842584 (2015)
A glyoxalase-1 knockdown does not have major short term effects on energy expenditure and atherosclerosis in mice.
2015 Scientific Article in PLoS Genetics PLoS Genet. 11:e1005561 (2015)
PPP2R5C couples hepatic glucose and lipid homeostasis.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 823-833 (2015)
The calcineurin-NFAT pathway controls activity-dependent circadian gene expression in slow skeletal muscle.
2015 Scientific Article in Diabetes Diabetes 65, 406-420 (2015)
Obesity in MENX rats is accompanied by high circulating levels of ghrelin and improved insulin sensitivity.
2015 Meeting abstract in Alcohol and Alcoholism Alcohol Alcohol. 50:SY14-4 (2015)
Primary hepatocellular damage and suppressed fat mobilization in heavy drinkers with PNPLA3 G genotype.
2015 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 6:129 (2015)
Transcriptional pathways in cPGI2-induced adipocyte progenitor activation for browning.
2015 Scientific Article in OncoTarget Oncotarget 6, 39111-39126 (2015)
Oncogenic features of the Bone Morphogenic Protein 7 (BMP7) in pheochromocytoma.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 732-740 (2015)
Molecular regulation of urea cycle function by the liver glucocorticoid receptor.
2015 Scientific Article in Nature Genetics Nat. Genet. 47, 969-978 (2015)
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.
2015 Scientific Article in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 421, 49-59 (2015)
Animal models of multiple endocrine neoplasia.
2015 Scientific Article in International Journal of Obesity Int. J. Obes. 39, 1733-1741 (2015)
Mesoderm Specific Transcript (MEST) is a negative regulator of human adipocyte differentiation.
2015 Meeting abstract in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 10:P62 (2015)
Mind the Ga(b)p! – a novel hepatic gatekeeper at the switch point of metabolic homeostasis and diabetic late complications controlled by reactive metabolites.
2015 Meeting abstract in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 10:P311 (2015)
Hepatic heat shock proteins in diabetes and long term diabetic complications.
2015 Meeting abstract in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 10:FV12 (2015)
Transforming growth factor beta-like stimulated clone 22 D4 promotes diabetic hyperglycemia and insulin resistance.
2015 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 7, 1048-1062 (2015)
Transcriptional co-factor Transducin Beta-Like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy.
2015 Scientific Article in Cell Metabolism Cell Metab. 21, 678-691 (2015)
Hematopoietic Kit deficiency, rather than lack of mast cells, protects mice from obesity and insulin resistance.
2015 Scientific Article in Journal of Nuclear Medicine J. Nucl. Med. 56, 839-846 (2015)
Semi-quantitative 123I-metaiodobenzylguanidine scintigraphy to distinguish pheochromocytoma and paraganglioma from physiological adrenal uptake and its correlation with genotype-dependent expression of catecholamine transporters.
2015 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 21, 3204-3215 (2015)
Targeting PI3K/mTOR signaling displays potent antitumor efficacy against nonfunctioning pituitary adenomas.
2015 Scientific Article in Theranostics Theranostics 5, 618-630 (2015)
Disclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imaging.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0118534 (2015)
Brown adipose tissue harbors a distinct sub-population of regulatory T cells.
2015 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 22, 353-367 (2015)
X-Linked Acrogigantism (X-LAG) syndrome: Clinical profile and therapeutic responses.
2015 Scientific Article in Endocrine Endocrine 49, 58-64 (2015)
Early onset acromegaly associated with a novel deletion in CDKN1B 5'UTR region.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0118534 (2015)
Brown adipose tissue harbors a distinct sub-population of regulatory T cells.
2015 Scientific Article in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 408, 178-184 (2015)
Adrenomedullary progenitor cells: Isolation and characterization of a multi-potent progenitor cell population.
2015 Scientific Article in Lancet, The Lancet 385, 392 (2015)
Ovarian hyperstimulation from ectopic hypersecretion of follicle stimulating hormone.
2015 Scientific Article in Endocrinology and Metabolism Endocrinol. Metab. 30, 389-394 (2015)
Acromegaly due to a macroinvasive plurihormonal pituitary adenoma and a rectal carcinoid tumor.
2015 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 22, 111-119 (2015)
SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary.
2015 Scientific Article in EMBO Journal, The EMBO J. 34, 344-360 (2015)