The research group of Prof. Ferruh Artunc, MD, focuses on the importance of the excretion of active proteases in the urine in nephrotic syndrome, which has been termed proteasuria. Current data suggest that proteasuria plays an important pathophysiological role in the development of typical complications of nephrotic syndrome such as sodium retention, hyperlipidaemia, hypercoagulability and progressive renal injury. The identification of the proteases involved could lay the foundation for new therapeutic approaches to treat patients with nephrotic syndrome by targeted inhibition of protease activity in the urine. In the nephrotic mouse model, this achieved a complete prevention of sodium retention without quantitatively reducing proteinuria (Bohnert et al. Kidney International 2018).
Professional Background
Conferral of the title of associate professor
Senior physician
Habilitation
Specialist for internal medicine
Honors and Awards
Paul Langerhans Prize of the German Diabetes Society
2023Nils Alwall Prize of the German Society for Nephrology
2019Special Award of the Scientific Institute of Nephrology
2018Abstract Prize 2018, 10th Annual Meeting of the German Society of Nephrology
2018Poster Prize 2013, 5th Annual Meeting of the German Society for Nephrology
2013