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Head of Division "Metabolic Neuroimaging"

Prof. Hubert Preissl

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Fields of Work and Expertise

fMRI Imaging  Artificial Intelligence Fetal programming Development functional Imaging 

 

  • Investigation of the structural and functional changes of the brain in prediabetics
  • Insulin action in the brain
  • Investigation of functional brain development and the autonomic nervous system in human foetuses using a non-invasive method (fetal magnetoencephalography and cardiography)

Professional Background

Since 2015

Professor, Institute for Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Munich at the University of Tübingen

Since 2011

Research group leader "Metabolic Neuroimaging" at the Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Munich at the University of Tübingen.

2000-2011

Project Director for fetal Magnetoencephalography at the University of Arkansas for Medical Sciences, Little Rock, USA.

1997-2015

Researcher at the MEG Center, University of Tübingen.

1994-1997

Postdoctoral research at the Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, under the supervision of Professor Niels Birbaumer.

1988 - 1994

Doctoral thesis (Physics) at the Max Planck Institute for Biological Cybernetics under the guidance of Professor Valentin Braitenberg.

1981-1988

Diploma in Physics, University of Regensburg and Tübingen

Hubert Preissl as a guest at Scobel, 3sat "Overweight: flaw or disease?"

What can successful prevention look like? Is the body mass index really the measure of all things, or are there other, more accurate methods to measure overweight?

Publications

Metabolism, DOI: 10.1016/j.metabol.2025.156430:156430 (2025)

Wang, Y. ; Sandforth, A. ; Jumpertz von Schwartzenberg, R. ; Ganslmeier, M. ; Cheng, Y. ; Sandforth, L. ; Katzenstein, S. ; Machann, J. ; Schick, F. ; Kantartzis, K. ; Preissl, H. ; Fritsche, A. ; Stefan, N. ; Bergman, M. ; Birkenfeld, A.L.

Lifestyle intervention is more effective in high 1-hour post-load glucose than in prediabetes for restoring β-cell function, reducing ectopic fat, and preventing type 2 diabetes.
Obes. Rev.:e70001 (2025)

Zhao, S. ; Semeia, L. ; Veit, R. ; Moser, J. ; Preissl, H. ; Kullmann, S.

Structural and functional brain changes in children and adolescents with obesity.
Sci. Transl. Med. 17:eadv7834 (2025)

Kullmann, S. ; Singh, A. ; Sehgal, R. ; Eichelmann, F. ; Sandforth, L. ; Wilms, B. ; Jähnert, M. ; Peter, A. ; Meyhöfer, S. ; Walther, D. ; Preissl, H. ; Häring, H.-U. ; Schulze, M.B. ; Heni, M. ; Birkenfeld, A.L. ; Schürmann, A. ; Ouni, M.

Circulating epigenetic signatures classifying brain insulin resistance in humans.
npj Imaging 3:49 (2025)

Gehmeyr, M. ; Rojas López, M.B. ; Nitkunanantharajah, S. ; Preissl, H. ; Vosseler, A. ; Jumpertz von Schwartzenberg, R. ; Birkenfeld, A.L. ; Katsouli, N. ; Fasoula, N. ; Karlas, A. ; Kallmayer, M. ; Ziegler, A.-G. ; Jüstel, D. ; Ntziachristos, V.

Enhanced maximum intensity projection (eMIP) for improving the fidelity of optoacoustic images.
Nat. Med. 31, 3330-3340 (2025)

Sandforth, A. ; Arreola, E.V. ; Hanson, R.L. ; Wewer Albrechtsen, N.J. ; Holst, J.J. ; Ahrends, R. ; Coman, C. ; Gerst, F. ; Lorza-Gil, E. ; Cheng, Y. ; Sandforth, L. ; Katzenstein, S. ; Ganslmeier, M. ; Seissler, J. ; Hauner, H. ; Perakakis, N. ; Wagner, R. ; Machann, J. ; Schick, F. ; Peter, A. ; Lehmann, R. ; Weigert, C. ; Maurer, J. ; Preissl, H. ; Heni, M. ; Szendrödi, J. ; Kopf, S. ; Solimena, M. ; Schwarz, P. ; Blüher, M. ; Häring, H.-U. ; Hrabě de Angelis, M. ; Schürmann, A. ; Kabisch, S. ; Mai, K. ; Pfeiffer, A.F.H. ; Bornstein, S. ; Stumvoll, M. ; Roden, M. ; Stefan, N. ; Fritsche, A. ; Birkenfeld, A.L. ; Jumpertz von Schwartzenberg, R.

Prevention of type 2 diabetes through prediabetes remission without weight loss.

Gallard, A. ; Brebion, B. ; Sippel, K. ; Zaylaa, A. ; Preissl, H. ; Moghimi, S. ; Fregier, Y. ; Wallois, F.

Transforming spontaneous premature neonatal EEG to spontaneous fetal MEG using a novel machine learning approach.
Appetite 214:108206 (2025)

Goll, N. ; Wiechers, C. ; Zinke, K. ; Preissl, H. ; Fritsche, A. ; Hallschmid, M.

Influence of maternal metabolism on neonate eating behaviour.
Early Hum. Dev. 206:106272 (2025)

Auchynnikava, V. ; Semeia, L. ; Sippel, K. ; Sbierski-Kind, J. ; Fritsche, A. ; Birkenfeld, A.L. ; Paluscke-Fröhlich, J. ; Wikström, A.K. ; Preissl, H.

Fetal heart rate variability in relation to maternal physical activity and metabolic health.
Diabetes Care 48, 996-1006 (2025)

Sandforth, L. ; Raverdy, V. ; Sandforth, A. ; Bauvin, P. ; Chatelain, E. ; Verkindt, H. ; Mingrone, G. ; Guidone, C. ; Verrastro, O. ; Zhou, K. ; Archid, R. ; Mihaljevic, A.L. ; Caiazzo, R. ; Baud, G. ; Marciniak, C. ; Chetboun, M. ; Ganslmeier, M. ; Minelli Faiao, V. ; Heni, M. ; Fritsche, L. ; Moller, A. ; Kantartzis, K. ; Peter, A. ; Lehmann, R. ; Wagner, R. ; Prystupa, K. ; Fritsche, A. ; Stefan, N. ; Preissl, H. ; Birkenfeld, A.L. ; Jumpertz von Schwartzenberg, R. ; Pattou, F.

Subphenotype-dependent benefits of bariatric surgery for individuals at risk for type 2 diabetes.
Brain Stimul. 18, 863-874 (2025)

Ester-Nacke, T. ; Veit, R. ; Thomanek, J. ; Book, M. ; Tamble, L. ; Beermann, M. ; Löffler, D. ; Salvador, R. ; Ruffini, G. ; Heni, M. ; Birkenfeld, A.L. ; Plewnia, C. ; Preissl, H. ; Kullmann, S.

Repeated net-tDCS of the hypothalamus appetite-control network enhances inhibitory control and decreases sweet food intake in persons with overweight or obesity.

Networks and Affiliations

Logo Deutsches Zentrum für Diabetesforschung;

German Center for Diabetes Research

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SSIB_logo_Society_for_the_study_of_ingestive_behaviour

Society for the Study of Ingestive Behavior (SSIB)

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Uppsala_University

Uppsala University

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Deutsche Adipositas Gesellschaft

Deutsche Adipositas-Gesellschaft e.V.

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Organization_of_Human_Brain_Mapping

Organization for Human Brain Mapping

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Society_for_Neuroendocrinology

British Society for Neuroendocrinology

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