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INTERACTOMICS

At INET we systematically generate molecular interactome maps by our well established AI informed and robotics supported protein-protein interaction pipeline integrating latest experimental and theoretical approaches.

In general our high-quality protein-protein interaction maps not only hasten the functional characterization of unknown proteins, including those with potential biotechnological utility, but also enable systems level investigations of genotype-to-phenotype relationships.  

 

Research

Systems Biology of Chlamydomonas reinhardtii metabolism BMBF eBio-Modul III- junior group funding

Extensive signal integration by the phytohormone protein network Altmann et al. Nature. 2020 DOI: 10.1038/s41586-020-2460-0 A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice

Wierbowski et al. Proc. Natl. Acad. Sci. U.S.A. 2020 DOI: 10.1073/pnas.1918068117

Binary Interactome Models of Inner- Versus Outer-Complexome Organization                                                  Lambourne et al bioRxiv. 2021 03.16.435663