Dr. Boyan Bonev
Principal Investigator Helmholtz Pioneer CampusResearch Area
Our long-term objective is to decipher the genetic and epigenetic blueprints of cortical development and evolution. To accomplish this, we study the interplay between transcription factors, 3D nuclear organization and gene expression in vivo and using cerebral organoids. Our research is highly interdisciplinary and combines developmental neurobiology, single cell –omics, mouse genetics, CRISPR-based techniques and computational biology.
Professional Background
Principal Investigator Helmholtz Pioneer Campus, Helmholtz Zentrum München
Postdoctoral Fellow Institute of Human Genetics – CNRS (France) Mentor: Giacomo Cavalli
Postdoctoral Fellow Harvard University (United States) Mentor: Paola Arlotta & John Rinn
Honors and Awards
EMBO Young Investigator Award
2022ERC Consolidator Award
2022ERA-NET Neuron Grant
2022Great Advances in Biology Award, French Academy of Sciences
2018Best Poster Award, EMBO Gene regulation in neural fate decisions
2017Sir Henry Wellcome Postdoctoral Fellowship
2013 - 2017Beddington Medal for best PhD thesis in Developmental Biology, British Society for Developmental Biology
2012Wellcome Trust PhD Fellowship
2007 - 2011Best Poster Award, Faculty Research Symposium Manchester
2011Best Presentation Award, Faculty Showcase Symposium, Manchester
2010
Publications
Read more2024 Nature Neuroscience
Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.
2024 Review in Nature Neuroscience
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.
2024 Scientific Article in Cell
Innate immune memory after brain injury drives inflammatory cardiac dysfunction.
2024 Scientific Article in Nature Neuroscience
Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1.
2024 Scientific Article in Journal of Neuroinflammation
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice.
2023 Scientific Article in Nature Cell Biology
Joint epigenome profiling reveals cell-type-specific gene regulatory programmes in human cortical organoids.
2022 Scientific Article in Nature Neuroscience
Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler.
2021 Letter to the Editor in Trends in Neurosciences