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Helmholtz Munich | ©Antonio Aguilar

Dr. Valérie Gailus-Durner

Scientific Head of the German Mouse Clinic (GMC)
+49 89 3187 3613VisitEmail meBuilding/Room: 35.14/314

“I want to understand the cause and the pathogenesis of genetic diseases. New scientific knowledge requires to work with the whole organism.”

“I want to understand the cause and the pathogenesis of genetic diseases. New scientific knowledge requires to work with the whole organism.”

Academic Pathway & Research Area

Valérie is a proud key founding member of the German Mouse Clinic and is leading the GMC as Scientific Head since 2001. She coordinated the setting up of the phenotyping pipelines, project and quality management as well as the assembly of a highly motivated team of scientists, technicians and project managers. Under her guidance the GMC established a reputation for excellence in phenotyping mouse mutants of human diseases.

Valérie has a keen interest to understand gene function by taking a systemic view at the whole organism and to identify new disease genes. Main research interests are metabolic diseases, rare diseases and ageing. She is participating in and coordinating several national and international multi-partner consortia and large-scale projects.

Valérie studied biology and received her PhD in biochemistry in 1994 from the University of Constance, Germany. She spent several years as a postdoctoral fellow at the Waksman Institute, Rutgers University, USA., supported by the German Research Foundation (DFG) as well as US fellowships. Her postdoctoral studies concentrated on genetics and transcriptional regulation of meiosis. In 1998, Valérie accepted a position at the GSF as senior scientist in bioinformatics at the Institute of Mammalian Genetics (Rudi Balling) where she worked on the analysis of complex regulatory transcriptional networks. In 2000 Valérie joined Martin Hrabé de Angelis’ new Institute of Experimental Genetics and together with her colleague Helmut Fuchs she established the first mouse clinic worldwide, the German Mouse Clinic. She served as executive board member of the first European Mouse Clinics (EUMODIC) and is member of the steering committee of the International Mouse Phenotyping Consortium (IMPC), a powerful network of mouse clinics for annotating the whole mammalian genome.

Valérie’s main ambition for the future is to make full use of the great potential of mouse models for human diseases and to make the enormous resource of phenotyping data more accessible for researchers and clinicians. New advanced methods will constantly improve pre-clinical models for studying treatments and genetic diseases, easing the translation to clinics.

Fields of Work and Expertise

mouse phenotypingrare diseasesageing

big data analysisnetworkingquality management

Private Facts

Next to her ambitions in science, supporting women in their careers is an important matter for Valérie. In this respect she is continuously serving as mentor in the Cross-Mentoring München program, which is supposed to foster women leaders and their careers in science and business.

Honors and Awards

  • Charles and Johanna Busch Biomedical fellowship

  • DFG postdoctoral fellowship

  • EC (EU) junior research fellowship for Genetic Engineering

Gold Star Awards Luxury Background
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Selected Publications