Helmholtz Munich

The young man at the doctor's office signs the documents.

In order to develop effective lifestyle intervention programs that are fully tailored to the individual needs of a person at risk of developing type 2 diabetes, more needs to be known about the mechanisms that determine the "response" or "non-response" to lifestyle intervention. This requires extremely accurate phenotyping and genotyping of individuals. With this in mind, the TULIP study (Tuebinger Lifestyle Intervention Program) was launched in 2003. The Germany-wide Prediabetes Lifestyle Intervention Study (PLIS), which has already been completed, aims to develop personalized prevention measures. In the IFIS study (Intermittent Fasting to Improve Insulin Secretion), we are investigating how intermittent fasting affects sugar metabolism in subtypes of prediabetes and diabetes. Gestational diabetes (PREG) is also being researched in several studies.

Diabetes concept with insulin, syringe, vials, pills, and stethoscope.

Ongoing trial

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Helmholtz Munich | Helmholtz Munich

Ongoing study

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Obesity overweight diabetes fitness abdomen adult background

We are Partner in the New Project on Early Stage Diabetes Detection

The BMBF funds a new project in the field of medical AI and systems medicine. The goal of the KI-DiabetesDetektion project is to integrate indication data from various sources in a knowledge graph and apply machine learning methods to improve the early stage detection of Diabetes.

Prof. Dr. Andreas Fritsche

Deputy Director View profile

Dr. Andreas Vosseler

Scientist

2021

Robert Wagner, Martin Heni, Adam G. Tabák, Jürgen Machann, Fritz Schick, Elko Randrianarisoa, Martin Hrabě de Angelis, Andreas L. Birkenfeld, Norbert Stefan, Andreas Peter, Hans-Ulrich Häring & Andreas Fritsche

Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes

2023

Andreas Fritsche

Insulin Secretion Capacity as a Crucial Feature to Distinguish Type 1 From Type 2 Diabetes and to Indicate the Need for Insulin Therapy - A Critical Discussion of the ADA/EASD Consensus Statement on the Management of Type 1 Diabetes in Adults

2023

Robert Wagner, Martin Heni, Konstantinos Kantartzis, Arvid Sandforth, Jürgen Machann, Fritz Schick, Andreas Peter, Louise Fritsche, Julia Szendrödi, Andreas F H Pfeiffer, Annette Schürmann, Matthias Blüher, Hans Hauner, Jochen Seissler, Stefan Bornstein, Michael Roden, Norbert Stefan, Andreas L Birkenfeld, Morris F White, Hans-Ulrich Häring, Andreas Fritsche

Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

2021

Andreas Fritsche, Robert Wagner, Martin Heni, Kostantinos Kantartzis, Jürgen Machann, Fritz Schick, Rainer Lehmann, Andreas Peter, Corinna Dannecker, Louise Fritsche, Vera Valenta, Renate Schick, Peter Paul Nawroth, Stefan Kopf, Andreas F H Pfeiffer, Stefan Kabisch, Ulrike Dambeck, Michael Stumvoll, Matthias Blüher, Andreas L Birkenfeld, Peter Schwarz, Hans Hauner, Julia Clavel, Jochen Seißler, Andreas Lechner, Karsten Müssig, Katharina Weber, Michael Laxy, Stefan Bornstein, Annette Schürmann, Michael Roden, Martin Hrabe de Angelis, Norbert Stefan, Hans-Ulrich Häring

Different Effects of Lifestyle Intervention in High- and Low-Risk Prediabetes: Results of the Randomized Controlled Prediabetes Lifestyle Intervention Study (PLIS)

2021

Marie Auzanneau, Andreas Fritsche, Andrea Icks, Erhard Siegel, Reinhold Kilian, Wolfram Karges, Stefanie Lanzinger, Reinhard W. Holl

Diabetes in the Hospital A Nationwide Analysis of All Hospitalized Cases in Germany With and Without Diabetes, 2015–2017