Publications Julia Hess
Trommer, M. ; Grohmann, M. ; Fabian, A. ; Ehret, F. ; Hess J. ; Rückert, M. ; Matschke, J.B. ; Stefanowicz, S. ; Rühle, A. ; Ferdinandus, S. ; Merten, R. ; Besserer, A. ; Schmidt, L. ; Sperk, E. ; Depardon, A. ; Putz, F. ; Petersen, C. ; Haderlein, M. ; Schröder, A. ; Weissmann, T. ; Deloch, L.
Balancing barriers: Family, career, and gender equality in radiation oncology and radiation research-An interdisciplinary prospective survey among the young workforce.Zhou, J. ; He, M. ; Zhao, Q. ; Shi, E. ; Wang, H. ; Ponkshe, V. ; Song, J. ; Wu, Z. ; Ji, D. ; Kranz, G. ; Tscherne, A. ; Schwenk-Zieger, S. ; Razak, N.A. ; Hess J. ; Belka, C. ; Zitzelsberger, H. ; Ourailidis, I. ; Stögbauer, F. ; Boxberg, M. ; Budczies, J. ; Reichel, C.A. ; Canis, M. ; Baumeister, P. ; Unger, K. ; Mock, A. ; Gires, O.
EGFR-mediated local invasiveness and response to Cetuximab in head and neck cancer.Marschner, S. ; Maihöfer, C. ; Späth, R. ; Haehl, E. ; Reitz, D. ; Kienlechner, N. ; Schüttrumpf, L. ; Baumeister, P. ; Pflugradt, U. ; Hess J. ; Zitzelsberger, H. ; Unger, K. ; Belka, C. ; Walter, F.
Adjuvant (chemo)radiotherapy for patients with head and neck cancer: Can comorbidity risk scores predict outcome?Danko, B. ; Hess J. ; Unger, K. ; Samaga, D. ; Walz, C. ; Walch, A.K. ; Sun, N. ; Baumeister, P. ; Zeng, P.Y.F. ; Walter, F. ; Marschner, S. ; Späth, R. ; Gires, O. ; Herkommer, T. ; Dazeh, R. ; Matos, T. ; Kreutzer, L. ; Matschke, J.B. ; Eul, K. ; Klauschen, F. ; Pflugradt, U. ; Canis, M. ; Ganswindt, U. ; Mymryk, J.S. ; Wollenberg, B. ; Nichols, A.C. ; Belka, C. ; Zitzelsberger, H. ; Lauber, K. ; Selmansberger, M.
Metabolic pathway-based subtypes associate glycan biosynthesis and treatment response in head and neck cancer.Budeus, B. ; Unger, K. ; Hess J. ; Sentek, H. ; Klein, D.
Comparative computational analysis to distinguish mesenchymal stem cells from fibroblasts.Burkart, S. ; Weusthof, C. ; Khorani, K. ; Steen, S. ; Stögbauer, F. ; Unger, K. ; Hess J. ; Zitzelsberger, H. ; Belka, C. ; Kurth, I. ; Hess, J.
A novel subgroup of UCHL1-related cancers is associated with genomic instability and sensitivity to DNA-damaging treatment.Schnöller, L.E. ; Piehlmaier, D. ; Weber, P. ; Brix, N. ; Fleischmann, D.F. ; Nieto, A.E. ; Selmansberger, M. ; Heider, T. ; Hess J. ; Niyazi, M. ; Belka, C. ; Lauber, K. ; Unger, K. ; Orth, M.
Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data.Unger, K. ; Hess J. ; Link, V. ; Buchner, A. ; Eze, C. ; Li, M. ; Stief, C. ; Kirchner, T. ; Klauschen, F. ; Zitzelsberger, H. ; Niyazi, M. ; Ganswindt, U. ; Schmidt-Hegemann, N.S. ; Belka, C.
DNA-methylation and genomic copy number in primary tumors and corresponding lymph node metastases in prostate cancer from patients with low and high Gleason score.Schinke, H. ; Shi, E. ; Lin, Z. ; Quadt, T. ; Kranz, G. ; Zhou, J. ; Wang, H. ; Hess J. ; Heuer, S. ; Belka, C. ; Zitzelsberger, H. ; Schumacher, U. ; Genduso, S. ; Riecken, K. ; Gao, Y. ; Wu, Z. ; Reichel, C.A. ; Walz, C. ; Canis, M. ; Unger, K. ; Baumeister, P. ; Pan, M. ; Gires, O.
A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer.Flach, S. ; Kumbrink, J. ; Walz, C. ; Hess J. ; Drexler, G. ; Belka, C. ; Canis, M. ; Jung, A. ; Baumeister, P.
Analysis of genetic variants of frequently mutated genes in human papillomavirus-negative primary head and neck squamous cell carcinoma, resection margins, local recurrences and corresponding circulating cell-free DNA.Lombardo, E. ; Hess J. ; Kurz, C. ; Riboldi, M. ; Marschner, S. ; Baumeister, P. ; Lauber, K. ; Pflugradt, U. ; Walch, A.K. ; Canis, M. ; Klauschen, F. ; Zitzelsberger, H. ; Belka, C. ; Landry, G. ; Unger, K.
DeepClassPathway: Molecular pathway aware classification using explainable deep learning.Hess J. ; Unger, K. ; Maihoefer, C. ; Schuettrumpf, L. ; Weber, P. ; Marschner, S. ; Wintergerst, L. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Soerensen, K. ; Baumann, M. ; Tinhofer, I. ; Combs, S.E. ; Debus, J. ; Schaefer, H. ; Krause, M. ; Linge, A. ; von der Gruen, J. ; Stuschke, M. ; Zips, D. ; Canis, M. ; Lauber, K. ; Ganswindt, U. ; Henke, M. ; Zitzelsberger, H. ; Belka, C.
Integration of p16/HPV DNA status with a 24-miRNA-defined molecular phenotype improves clinically relevant stratification of head and neck cancer patients.Kreutzer, L. ; Weber, P. ; Heider, T. ; Heikenwaelder, M. ; Riedl, T. ; Baumeister, P. ; Klauschen, F. ; Belka, C. ; Walch, A.K. ; Zitzelsberger, H. ; Hess J. ; Unger, K.
Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.Tiwari, D.K. ; Hannen, R. ; Unger, K. ; Kohl, S. ; Hess J. ; Lauber, K. ; Subtil, F.S.B. ; Dikomey, E. ; Engenhart-Cabillic, R. ; Schötz, U.
IL1 pathway in HPV-negative HNSCC cells is an indicator of radioresistance after photon and carbon ion irradiation without functional involvement.Schnöller, L.E. ; Albrecht, V. ; Brix, N. ; Nieto, A.E. ; Fleischmann, D.F. ; Niyazi, M. ; Hess J. ; Belka, C. ; Unger, K. ; Lauber, K. ; Orth, M.
Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy.Thomsen, A.R. ; Aldrian, C. ; Luka, B. ; Hornhardt, S. ; Gomolka, M. ; Moertl, S. ; Hess J. ; Zitzelsberger, H. ; Heider, T. ; Schlueter, N. ; Rau, S. ; Monroy Ordonez, B. ; Schäfer, H. ; Rücker, G. ; Henke, M.
Biopsy-derived oral keratinocytes – A model to potentially test for oral mucosa radiation sensitivity.Weber, P. ; Künstner, A. ; Hess J. ; Unger, K. ; Marschner, S. ; Idel, C. ; Ribbat-Idel, J. ; Walz, C. ; Rietzler, S. ; Valeanu, L. ; Herkommer, T. ; Kreutzer, L. ; Klymenko, O. ; Kirchner, T. ; Ganswindt, U. ; Walch, A.K. ; Sterr, M. ; Lickert, H. ; Canis, M. ; Rades, D. ; Perner, S. ; Berriel Diaz, M. ; Herzig, S. ; Wollenberg, B. ; Busch, H. ; Zitzelsberger, H.
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.Weiss, B.G. ; Anczykowski, M.Z. ; Ihler, F. ; Bertlich, M. ; Spiegel, J.L. ; Haubner, F. ; Canis, M. ; Küffer, S. ; Hess J. ; Unger, K. ; Kitz, J. ; Jakob, M.
MicroRNA-182-5p and microRNA-205-5p as potential biomarkers for prognostic stratification of p16-positive oropharyngeal squamous cell carcinoma.Schoetz, U. ; Klein, D. ; Hess J. ; Shnayien, S. ; Spoerl, S. ; Orth, M. ; Mutlu, S. ; Hennel, R. ; Sieber, A. ; Ganswindt, U. ; Luka, B. ; Thomsen, A.R. ; Unger, K. ; Jendrossek, V. ; Zitzelsberger, H. ; Bluethgen, N. ; Belka, C. ; Unkel, S. ; Klinger, B. ; Lauber, K.
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma.Tawk, B. ; Wirkner, U. ; Schwager, C. ; Rein, K. ; Zaoui, K. ; Federspil, P.A. ; Adeberg, S. ; Linge, A. ; Ganswindt, U. ; Hess J. ; Unger, K. ; Tinhofer, I. ; Budach, V. ; Lohaus, F. ; Krause, M. ; Guberina, M. ; Stuschke, M. ; Balermpas, P. ; Rödel, C. ; Grosu, A.L. ; Schäfer, H. ; Zips, D. ; Combs, S.E. ; Pigorsch, S. ; Zitzelsberger, H. ; Baumeister, P. ; Kirchner, T. ; Bewerunge-Hudler, M. ; Weichert, W. ; Hess, J. ; Herpel, E. ; Belka, C. ; Baumann, M. ; Debus, J. ; Abdollahi, A.
Tumor DNA-methylome derived epigenetic fingerprint identifies HPV-negative head and neck patients at risk for locoregional recurrence after postoperative radiochemotherapy.Jakob, M. ; Mattes, L.M. ; Unger, K. ; Kueffer, S. ; Hess J. ; Canis, M. ; Schirmer, M. ; Spiegel, J.L. ; Haubner, F. ; Ihler, F. ; Weiss, B.G. ; Kitz, J.
Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma.Krug, D. ; Hecht, M. ; Ebert, N. ; Maurer, M. ; Fleischmann, D.F. ; Fokas, E. ; Straube, C. ; Nicolay, N.H. ; Hörner-Rieber, J. ; Schmitt, D. ; von Neubeck, C. ; Zamboglou, C. ; Sperk, E. ; Kaul, D. ; Hess J. ; Corradini, S. ; Seidel, C. ; Gani, C. ; Baues, C. ; Frey, B. ; Blanck, O. ; Gauer, T. ; Niyazi, M.
Correction to: Innovative radiation oncology Together-Precise, Personalized, Human.Krug, D. ; Hecht, M. ; Ebert, N. ; Maurer, M. ; Fleischmann, D.F. ; Fokas, E. ; Straube, C. ; Nicolay, N.H. ; Hörner-Rieber, J. ; Schmitt, D. ; von Neubeck, C. ; Zamboglou, C. ; Sperk, E. ; Kaul, D. ; Hess J. ; Corradini, S. ; Seidel, C. ; Gani, C. ; Baues, C. ; Frey, B. ; Blanck, O. ; Gauer, T. ; Niyazi, M.
Innovative radiation oncology Together – Precise, Personalized, Human: Vision 2030 for radiotherapy & radiation oncology in Germany.Hansel, C. ; Barr, S. ; Schemann, A.V. ; Lauber, K. ; Hess J. ; Unger, K. ; Zitzelsberger, H. ; Jendrossek, V. ; Klein, D.
Metformin protects against radiation-induced acute effects by limiting senescence of bronchial-epithelial cells.Hirschberger, S. ; Strauß, G. ; Effinger, D. ; Marstaller, X. ; Ferstl, A. ; Müller, M.B. ; Wu, T. ; Hübner, M. ; Rahmel, T. ; Mascolo, H. ; Exner, N. ; Hess J. ; Kreth, F.W. ; Unger, K. ; Kreth, S.
Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming.Stadler, D. ; Kächele, M. ; Jones, A. ; Hess J. ; Urban, C. ; Schneider, J. ; Xia, Y. ; Oswald, A. ; Nebioglu, F. ; Bester, R. ; Lasitschka, F. ; Ringelhan, M. ; Ko, C. ; Chou, W.M. ; Geerlof, A. ; van de Klundert, M. ; Wettengel, J.M. ; Schirmacher, P. ; Heikenwälder, M. ; Schreiner, S. ; Bartenschlager, R. ; Pichlmair, A. ; Sattler, M. ; Unger, K. ; Protzer, U.
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.Orth, M. ; Albrecht, V. ; Seidl, K. ; Kinzel, L. ; Unger, K. ; Hess J. ; Kreutzer, L. ; Sun, N. ; Stegen, B. ; Nieto, A. ; Maas, J. ; Winssinger, N. ; Friedl, A.A. ; Walch, A.K. ; Belka, C. ; Zitzelsberger, H. ; Niyazi, M. ; Lauber, K.
Inhibition of HSP90 as a strategy to radiosensitize glioblastoma: Targeting the DNA damage response and beyond.Ogundipe, V.M.L. ; Groen, A.H. ; Hosper, N. ; Nagle, P.W.K. ; Hess J. ; Faber, H. ; Jellema, A.L. ; Baanstra, M. ; Links, T.P. ; Unger, K. ; Plukker, J.T.M. ; Coppes, R.P.
Generation and differentiation of adult tissue-derived human thyroid organoids.Schinke, H. ; Heider, T. ; Herkommer, T. ; Simon, F. ; Blancke Soares, A. ; Kranz, G. ; Samaga, D. ; Dajka, L. ; Feuchtinger, A. ; Walch, A.K. ; Valeanu, L. ; Walz, C. ; Kirchner, T. ; Canis, M. ; Baumeister, P. ; Belka, C. ; Maihöfer, C. ; Marschner, S. ; Pflugradt, U. ; Ganswindt, U. ; Hess J. ; Zitzelsberger, H. ; Gires, O.
Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas.Fleischmann, D.F. ; Unger, K. ; Ruf, V. ; Heider, T. ; Hess J. ; Drexler, G. ; Herms, J. ; Thon, N. ; Kreth, F.-. ; Tonn, J.-. ; Zitzelsberger, H. ; Lauber, K. ; Belka, C. ; Niyazi, M.
Risk Stratification of Glioblastoma Patients using Blood Plasma Samples.Schmidt-Hegemann, N.-S. ; Hess J. ; Unger, K. ; Link, V. ; Buchner, A. ; Eze, C. ; Li, M. ; Stief, C. ; Kirchner, T. ; Ganswindt, U. ; Zitzelsberger, H. ; Belka, C.
DNA copy number and DNA methylome analysis of primary prostate cancer and pathologic lymph node metastases in patients with low and high Gleason score.Hansel, C. ; Wiesemann, A. ; Lauber, K. ; Hess J. ; Unger, K. ; Zitzelsberger, H. ; Jendrossek, V. ; Klein, D.
Radiation-induced senescence as potential target for normal tissue protection.Mutlu, S. ; Unger, K. ; Brix, N. ; Heider, T. ; Maier, S. ; Branz, P. ; Hess J. ; Belka, C. ; Zitzelsberger, H. ; Lauber, K.
Intrinsic radioresistance and intra-tumoral heterogeneity in HNSCC.Drexler, G.A. ; Klymenko, O. ; Baumeister, P. ; Weber, P. ; Heider, T. ; Selmansberger, M. ; Zitzelsberger, H. ; Unger, K. ; Hess J. ; Schoetz, U. ; Belka, C. ; Lauber, K.
Patient-derived HNSCC cell lines and subclones reflect inter- and intra-tumoral heterogeneity regarding various molecular and phenotypic aspects.Unger, K. ; Fleischmann, D.F. ; Ruf, V. ; Felsberg, J. ; Piehlmaier, D. ; Samaga, D. ; Hess J. ; Suresh, M.P. ; Mittelbronn, M. ; Lauber, K. ; Budach, W. ; Säbel, M. ; Rödel, C. ; Reifenberger, G. ; Herms, J. ; Tonn, J.C. ; Zitzelsberger, H. ; Belka, C. ; Niyazi, M.
Improved risk stratification in younger IDH wild-type glioblastoma patients by combining a 4-miRNA signature with MGMT promoter methylation status.Selmansberger, M. ; Michna, A. ; Braselmann, H. ; Höfig, I. ; Schorpp, K.K. ; Weber, P. ; Anastasov, N. ; Zitzelsberger, H. ; Hess J. ; Unger, K.
Transcriptome network of the papillary thyroid carcinoma radiation marker CLIP2.Samaga, D. ; Hornung, R. ; Braselmann, H. ; Hess J. ; Zitzelsberger, H. ; Belka, C. ; Boulesteix, A.L. ; Unger, K.
Single-center versus multi-center data sets for molecular prognostic modeling: A simulation study.Schüttrumpf, L. ; Marschner, S. ; Scheu, K. ; Hess J. ; Rietzler, S. ; Walch, A.K. ; Baumeister, P. ; Kirchner, T. ; Ganswindt, U. ; Zitzelsberger, H. ; Belka, C. ; Maihoefer, C.
Definitive chemoradiotherapy in patients with squamous cell cancers of the head and neck-results from an unselected cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".Unger, K. ; Fleischmann, D.F. ; Ruf, V. ; Felsberg, J. ; Piehlmaier, D. ; Samaga, D. ; Hess J. ; Mittelbronn, M. ; Lauber, K. ; Budach, W. ; Säbel, M. ; Rödel, C. ; Reifenberger, G. ; Herms, J. ; Tonn, J.C. ; Zitzelsberger, H. ; Belka, C. ; Niyazi, M.
4-miRNA signature and MGMT promoter methylation improve risk stratisfaction in glioblastoma.Steens, J. ; Unger, K. ; Klar, L. ; Neureiter, A. ; Wieber, K. ; Hess J. ; Jakob, H.G. ; Klump, H. ; Klein, D.
Direct conversion of human fibroblasts into therapeutically active vascular wall-typical mesenchymal stem cells.Jakob, M. ; Mattes, L. ; Küffer, S. ; Unger, K. ; Hess J. ; Bertlich, M. ; Haubner, F. ; Ihler, F. ; Canis, M. ; Weiss, B. ; Kitz, J.
MicroRNA expression patterns in oral squamous cell carcinoma: Hsa-mir-99b-3p and hsa-mir-100-5p as novel prognostic markers for oral cancer.Unger, K. ; Fleischmann, D.F. ; Ruf, V. ; Felsberg, J. ; Piehlmaier, D. ; Hess J. ; Mittelbronn, M. ; Lauber, K. ; Budach, W. ; Roedel, C. ; Säbel, M. ; Reifenberger, G. ; Herms, J. ; Zitzelsberger, H. ; Belka, C. ; Niyazi, M.
Validation of a 4-miRNA prognosticator allowing for improved risk stratification of glioblastoma patients in combination with MGMT promoter methylation status.Schötz, U. ; Shnayien, S. ; Spoel, S. ; Kinzel, L. ; Maihöfer, C. ; Hess J. ; Zitzelsberger, H. ; Klein, D. ; Jendrossek, V. ; Klinger, B. ; Sieber, A. ; Bluehgen, N. ; Belka, C. ; Unkel, S. ; Lauber, K.
Inherent resistance of head and neck tumors: Cellular senescence and associated cyokine production as key mechanisms in vitro and in vivo.Klymenko, O. ; Drexler, G.A. ; Baumeister, P. ; Weber, P. ; Zitzelsberger, H. ; Unger, K. ; Hess J. ; Schoetz, U. ; Belka, C. ; Lauber, K.
Patient-derived HNSCC cell lines and subclones reflect inter- and intra-tumoral heterogeneity regarding genomic copy number alterations and radiation response.Wintergerst, L. ; Selmansberger, M. ; Maihoefer, C. ; Schuettrumpf, L. ; Walch, A.K. ; Wilke, C. ; Pitea, A. ; Woischke, C. ; Baumeister, P. ; Kirchner, T. ; Belka, C. ; Ganswindt, U. ; Zitzelsberger, H. ; Unger, K. ; Hess J.
A 16q24.3 4-gene mRNA signature predicts outcome in radio(chemo)therapy-treated head and neck squamous cell carcinoma.Osterode, E. ; Schoetz, U. ; Orth, M. ; Selmansberger, M. ; Schuster, J. ; Hess J. ; Unger, K. ; Zitzelsberger, H. ; Belka, C. ; Lauber, K.
Evaluation of CD44v6 targeting strategies in HNSCC.Piehlmaier, D. ; Stegen, B. ; Nieto, A. ; Orth, M. ; Niyazi, M. ; Ruf, V. ; Selmansberger, M. ; Unkel, S. ; Hess J. ; Zitzelsberger, H. ; Lauber, K. ; Unger, K.
In-vitro and in-vivo characterization of a glioblastoma cell line panel.Hess J. ; Unger, K. ; Maihoefer, C. ; Schuettrumpf, L. ; Schneider, L. ; Heider, T. ; Weber, P. ; Marschner, S. ; Braselmann, H. ; Kuger, S. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Werner, K. ; Baumann, M. ; Budach, V. ; Combs, S.E. ; Debus, J. ; Grosu, A.-L. ; Krause, M. ; Roedel, C. ; Stuschke, M. ; Zips, D. ; Zitzelsberger, H. ; Ganswindt, U. ; Henke, M. ; Belka, C.
A five-microRNA-signature predicts recurrence and survival in HPV-negative HNSCC.Weber, J. ; de la Rosa, J. ; Grove, C.S. ; Schick, M. ; Rad, L. ; Baranov, O. ; Strong, A. ; Pfaus, A. ; Friedrich, M.J. ; Engleitner, T. ; Lersch, R. ; Öllinger, R. ; Grau, M. ; Menendez, I.G. ; Martella, M. ; Kohlhofer, U. ; Banerjee, R. ; Turchaninova, M.A. ; Scherger, A. ; Hoffman, G.J. ; Hess J. ; Kuhn, L. ; Ammon, T. ; Kim, J. ; Schneider, G. ; Unger, K. ; Zimber-Strobl, U. ; Heikenwälder, M. ; Schmidt-Supprian, M. ; Yang, F. ; Saur, D. ; Liu, P. ; Steiger, K. ; Chudakov, D.M. ; Lenz, G. ; Quintanilla-Martinez, L. ; Keller, U. ; Vassiliou, G.S. ; Cadiñanos, J. ; Bradley, A. ; Rad, R.
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice.Hess J. ; Unger, K. ; Maihoefer, C. ; Schüttrumpf, L. ; Wintergerst, L. ; Heider, T. ; Weber, P. ; Marschner, S. ; Braselmann, H. ; Samaga, D. ; Kuger, S. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Werner, K. ; Baumann, M. ; Budach, V. ; Combs, S.E. ; Debus, J. ; Grosu, A.-L. ; Krause, M. ; Linge, A. ; Rödel, C. ; Stuschke, M. ; Zips, D. ; Zitzelsberger, H. ; Ganswindt, U. ; Henke, M. ; Belka, C.
A five-microRNA signature predicts survival and disease control of patients with head and neck cancer negative for HPV-infection.Mueller, S. ; Engleitner, T. ; Maresch, R. ; Zukowska, M. ; Lange, S. ; Kaltenbacher, T. ; Konukiewitz, B. ; Oellinger, R. ; Zwiebel, M. ; Strong, A. ; Yen, H.Y. ; Banerjee, R. ; Louzada, S. ; Fu, B. ; Seidler, B. ; Goetzfried, J. ; Schuck, K. ; Hassan, Z. ; Schoenhuber, N. ; Klein, S. ; Veltkamp, C. ; Friedrich, M. ; Rad, L. ; Barenboim, M. ; Ziegenhain, C. ; Hess J. ; Dovey, O.M. ; Eser, S. ; Parekh, S. ; Constantino-Casas, F. ; de la Rosa, J. ; Sierra, M.I. ; Fraga, M. ; Mayerle, J. ; Kloeppel, G. ; Schmid, R.M. ; Cadiñanos, J. ; Liu, P. ; Vassiliou, G.S. ; Weichert, W. ; Steiger, K. ; Enard, W. ; Yang, F. ; Unger, K. ; Schneider, G. ; Varela, I. ; Bradley, A. ; Saur, D. ; Rad, R.
Evolutionary trajectories and KRAS gene dosage define pancreatic cancer phenotypes.Baumeister, P. ; Hollmann, A. ; Kitz, J. ; Afthonidou, A. ; Simon, F. ; Shakhtour, J. ; Mack, B. ; Kranz, G. ; Libl, D. ; Leu, M. ; Schirmer, M.A. ; Canis, M. ; Belka, C. ; Zitzelsberger, H. ; Ganswindt, U. ; Hess J. ; Jakob, M. ; Unger, K. ; Gires, O.
High expression of EpCAM and Sox2 is a positive prognosticator of clinical outcome for head and neck carcinoma.Pan, M. ; Schinke, H. ; Luxenburger, E. ; Kranz, G. ; Shakhtour, J. ; Libl, D. ; Huang, Y. ; Gaber, A. ; Pavšič, M. ; Lenarčič, B. ; Kitz, J. ; Jakob, M. ; Schwenk-Zieger, S. ; Canis, M. ; Hess J. ; Unger, K. ; Baumeister, P. ; Gires, O.
EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers.Wintergerst, L. ; Selmansberger, M. ; Maihoefer, C. ; Schüttrumpf, L. ; Walch, A.K. ; Wilke, C. ; Pitea, A. ; Woischke, C. ; Baumeister, P. ; Kirchner, T. ; Belka, C. ; Ganswindt, U. ; Zitzelsberger, H. ; Unger, K. ; Hess J.
A prognostic mRNA expression signature of four 16q24.3 genes in radio(chemo)therapy-treated head and neck squamous cell carcinoma (HNSCC).Klymenko, O. ; Baumeister, P. ; Zitzelsberger, H. ; Unger, K. ; Hess J. ; Schoetz, U. ; Belka, C. ; Lauber, K.
HNSCC derived cell lines and subclones differ in genomic copy number changes and radiation response.Schoetz, U. ; Orth, M. ; Selmansberger, M. ; Schuster, J. ; Stegen, B. ; Hess J. ; Unger, K. ; Zitzelsberger, H. ; Belka, C. ; Engenhart-Cabillic, R. ; Lauber, K.
Prognostic biomarkers and targets for personalization of radiotherapy of HNSCC: CD44v6.Maihoefer, C. ; Schüttrumpf, L. ; Macht, C. ; Pflugradt, U. ; Hess J. ; Schneider, L. ; Woischke, C. ; Walch, A.K. ; Baumeister, P. ; Kirchner, T. ; Zitzelsberger, H. ; Belka, C. ; Ganswindt, U.
Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".Wilke, C. ; Braselmann, H. ; Hess J. ; Klymenko, S.V. ; Chumak, V.V. ; Zakhartseva, L.M. ; Bakhanova, E.V. ; Walch, A.K. ; Selmansberger, M. ; Samaga, D. ; Weber, P. ; Schneider, L. ; Fend, F. ; Bösmüller, H.C. ; Zitzelsberger, H. ; Unger, K.
A genomic copy number signature predicts radiation exposure in post-Chernobyl breast cancer.Mueller, S. ; Engleitner, T. ; Maresch, R. ; Zukowska, M. ; Lange, S. ; Kaltenbacher, T. ; Konukiewitz, B. ; Öllinger, R. ; Zwiebel, M. ; Strong, A. ; Yen, H.Y. ; Banerjee, R. ; Louzada, S. ; Fu, B. ; Seidler, B. ; Götzfried, J. ; Schuck, K. ; Hassan, Z. ; Arbeiter, A. ; Schönhuber, N. ; Klein, S. ; Veltkamp, C. ; Friedrich, M. ; Rad, L. ; Barenboim, M. ; Ziegenhain, C. ; Hess J. ; Dovey, O.M. ; Eser, S. ; Parekh, S. ; Constantino-Casas, F. ; de la Rosa, J. ; Sierra, M.I. ; Fraga, M. ; Mayerle, J. ; Klöppel, G. ; Cadiñanos, J. ; Liu, P. ; Vassiliou, G.S. ; Weichert, W. ; Steiger, K. ; Enard, W. ; Schmid, R.M. ; Yang, F. ; Unger, K. ; Schneider, G. ; Varela, I. ; Bradley, A. ; Saur, D. ; Rad, R.
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.Wilke, C. ; Hess J. ; Klymenko, S.V. ; Chumak, V.V. ; Zakhartseva, L.M. ; Bakhanova, E.V. ; Feuchtinger, A. ; Walch, A.K. ; Selmansberger, M. ; Braselmann, H. ; Schneider, L. ; Pitea, A. ; Steinhilber, J. ; Fend, F. ; Bösmüller, H.C. ; Zitzelsberger, H. ; Unger, K.
Expression of miRNA-26b-5p and its target TRPS1 is associated with radiation exposure in post-Chernobyl breast cancer.Maihoefer, C. ; Kienlechner, N. ; Schttrumpf, L. ; Baumeister, P. ; Macht, C. ; Pflugradt, U. ; Hess J. ; Zitzelsberger, H. ; Friedl, A.A. ; Belka, C. ; Ganswindt, U.
The influence of anemia, nicotine abuse and co-morbidities in patients with adjuvant radio(chemo)therapy in HNSCC.Piehlmaier, D. ; Stegen, B. ; Nieto, A. ; Orth, M. ; Niyazi, M. ; Ruf, V. ; Hess J. ; Zitzelsberger, H. ; Lauber, K. ; Unger, K.
In-vitro and in-vivo characterization of a glioblastoma cell line panel.Schoetz, U. ; Orth, M. ; Selmansberger, M. ; Schuster, J. ; Stegen, B. ; Ganswindt, U. ; Maihoefer, C. ; Schuettrumpf, L. ; Hess J. ; Unger, K. ; Zitzelsberger, H. ; Belka, C. ; Lauber, K.
Increased CD44v6 expression confers radioresistance in subsets of HNSCC.Wunderlich, R. ; Unger, K. ; Hess J. ; Lauber, K. ; Frey, B. ; Gaipl, U. ; Zitzelsberger, H.
Irradiated HPV+ head and neck cancer cells induce an interferon related gene expression in various innate immune cell subtypes.Schneider, L. ; Selmansberger, M. ; Schuettrumpf, L. ; Maihoefer, C. ; Pflugradt, U. ; Kirchner, T. ; Woischke, C. ; Belka, C. ; Zitzelsberger, H. ; Ganswindt, U. ; Unger, K. ; Hess J.
Subgroups of HPV-positive and HPV-negative head and neck squamous cell carcinoma differing in global copy number changes and prognosis.Steens, J. ; Zuk, M. ; Benchellal, M. ; Bornemann, L. ; Teichweyde, N. ; Hess J. ; Unger, K. ; Görgens, A. ; Klump, H. ; Klein, D.
In vitro generation of vascular wall-resident multipotent stem cells of mesenchymal nature from murine induced pluripotent stem cells.Wunderlich, R. ; Rühle, P.F. ; Deloch, L. ; Unger, K. ; Hess J. ; Zitzelsberger, H. ; Lauber, K. ; Frey, B. ; Gaipl, U.S.
Interconnection between DNA damage, senescence, inflammation, and cancer.Hall, J. ; Jeggo, P.A. ; West, C. ; Gomolka, M. ; Quintens, R. ; Badie, C. ; Laurent, O. ; Aerts, A.L. ; Anastasov, N. ; Azimzadeh, O. ; Azizova, T.V. ; Baatout, S. ; Baselet, B. ; Benotmane, M.A. ; Blanchardon, E. ; Guéguen, Y. ; Haghdoost, S. ; Harms-Ringhdahl, M. ; Hess J. ; Kreuzer, M. ; Laurier, D. ; Macaeva, E. ; Manning, G. ; Pernot, E. ; Ravanat, J.L. ; Sabatier, L. ; Tack, K. ; Tapio, S. ; Zitzelsberger, H. ; Cardis, E.
Ionizing radiation biomarkers in epidemiological studies – An update.Hess J. ; Unger, K. ; Orth, M. ; Schötz, U. ; Schüttrumpf, L. ; Zangen, V. ; Gimenez-Aznar, I. ; Michna, A. ; Schneider, L. ; Stamp, R. ; Selmansberger, M. ; Braselmann, H. ; Hieber, L. ; Drexler, G.A. ; Kuger, S. ; Klein, D. ; Jendrossek, V. ; Friedl, A.A. ; Belka, C. ; Zitzelsberger, H. ; Lauber, K.
Genomic amplification of Fanconi anemia complementation group A (FancA) in head and neck squamous cell carcinoma (HNSCC): Cellular mechanisms of radioresistance and clinical relevance.Michna, A. ; Braselmann, H. ; Selmansberger, M. ; Dietz, A. ; Hess J. ; Gomolka, M. ; Hornhardt, S. ; Blüthgen, N. ; Zitzelsberger, H. ; Unger, K.
Natural cubic spline regression modeling followed by dynamic network reconstruction for the identification of radiation-sensitivity gene association networks from time-course transcriptome data.Michna, A. ; Schötz, U. ; Selmansberger, M. ; Zitzelsberger, H. ; Lauber, K. ; Unger, K. ; Hess J.
Transcriptomic analyses of the radiation response in head and neck squamous cell carcinoma subclones with different radiation sensitivity: Time-course gene expression profiles and gene association networks.Badie, C. ; Hess J. ; Zitzelsberger, H. ; Kulka, U.
Established and emerging biomarkers of radiation exposure.Sass, S. ; Pitea, A. ; Unger, K. ; Hess J. ; Müller, N.S. ; Theis, F.J.
MicroRNA-target network inference and local network enrichment analysis identify two microRNA clusters with distinct functions in head and neck squamous cell carcinoma.Hess J. ; Gimenez-Aznar, I. ; Michna, A. ; Kuger, S. ; Klein, D. ; Schoetz, U. ; Orth, M. ; Hieber, L. ; Braselmann, H. ; Schuettrumpf, L. ; Jendrossek, V. ; Belka, C. ; Zangen, V. ; Unger, K. ; Zitzelsberger, H. ; Lauber, K.
Signalling networks associated with FancA mediated radioresistance in cells of head and neck squamous cell carcinoma.Kuger, S. ; Hess J. ; Schötz, U. ; Gimenez-Aznar, I. ; Michna, A. ; Orth, M. ; Hieber, L. ; Braselmann, H. ; Klein, D. ; Schuettrumpf, L. ; Jendrossek, V. ; Belka, C. ; Zangen, V. ; Unger, K. ; Zitzelsberger, H. ; Lauber, K.
The influence of FancA overexpression on radioresistance in oral keratinocytes and HNSCC cells.Schoetz, U. ; Shnayien, S. ; Kinzel, L. ; Hess J. ; Zitzelsberger, H. ; Klein, D. ; Jendrossek, V. ; Belka, C. ; Unkel, S. ; Lauber, K.
Inherent radioresistance of head and neck squamous cell carcinoma cells: Principal component analysis identifies cellular senescence as a crucial driver.Schneider, L. ; Belka, C. ; Budach, W. ; Zitzelsberger, H. ; Unger, K. ; Hess J.
Identification and validation of predictive markers in head and neck squamous cell carcinomas.Braselmann, H. ; Michna, A. ; Hess J. ; Unger, K.
CFAssay: Statistical analysis of the colony formation assay.Gimenez-Aznar, I. ; Michna, A. ; Ludwig, H. ; Braselmann, H. ; Klein, D. ; Ohrt, M. ; Schoetz, U. ; Kuger, S. ; Schneider, L. ; Schuettrumpf, L. ; Jendrossek, V. ; Belka, C. ; Zangen, V. ; Unger, K. ; Zitzelsberger, H. ; Lauber, K. ; Hess J.
Fanconi anemia, complementation group A (FancA) overexpression confers radioresistance to oral keratinocytes.Summerer, I. ; Hess J. ; Pitea, A. ; Unger, K. ; Hieber, L. ; Selmansberger, M. ; Lauber, K. ; Zitzelsberger, H.
Integrative analysis of the microRNA-mRNA response to radiochemotherapy in primary head and neck squamous cell carcinoma cells.Selmansberger, M. ; Braselmann, H. ; Hess J. ; Bogdanova, T. ; Abend, M. ; Tronko, M. ; Brenner, A. ; Zitzelsberger, H. ; Unger, K.
Genomic copy number analysis of Chernobyl papillary thyroid carcinoma in the Ukrainian-American Cohort.Groß, C. ; Steiger, K. ; Sayyed, S. ; Heid, I. ; Feuchtinger, A. ; Walch, A.K. ; Hess J. ; Unger, K. ; Zitzelsberger, H. ; Settles, M. ; Schlitter, A.M. ; Dworniczak, J. ; Altomonte, J. ; Ebert, O. ; Schwaiger, M. ; Rummeny, E.J. ; Steingötter, A. ; Esposito, I. ; Braren, R.
Model matters: Differences in orthotopic rat hepatocellular carcinoma physiology determine therapy response to sorafenib.Selmansberger, M. ; Kaiser, J.C. ; Hess J. ; Güthlin, D. ; Likhtarov, I. ; Shpak, V. ; Tronko, M. ; Brenner, A. ; Abend, M. ; Blettner, M. ; Unger, K. ; Jacob, P. ; Zitzelsberger, H.
Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas.Summerer, I. ; Niyazi, M. ; Unger, K. ; Pitea, A. ; Zangen, V. ; Hess J. ; Atkinson, M.J. ; Belka, C. ; Mörtl, S. ; Zitzelsberger, H.
Erratum: Changes in circulating microRNAs after radiochemotherapy in head and neck cancer patients.Schuster, F.R. ; Stanglmaier, M. ; Woessmann, W. ; Winkler, B. ; Siepermann, M. ; Meisel, R. ; Schlegel, P.G. ; Hess J. ; Lindhofer, H.G. ; Borkhardt, A. ; Buhmann, R.
Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies.Selmansberger, M. ; Feuchtinger, A. ; Zurnadzhy, L. ; Michna, A. ; Kaiser, J.C. ; Abend, M. ; Brenner, A. ; Bogdanova, T. ; Walch, A.K. ; Unger, K. ; Zitzelsberger, H. ; Hess J.
CLIP2 as radiation biomarker in papillary thyroid carcinoma.Gimenez-Aznar, I. ; Michna, A. ; Hieber, L. ; Braselmann, H. ; Jendrossek, V. ; Zangen, V. ; Unger, K. ; Zitzelsberger, H. ; Lauber, K. ; Hess J.
FancA overexpression confers radioresistance to cells of head and neck squamous cell carcinoma.Wilke, C. ; Hess J. ; Pitea, A. ; Schmidl, D. ; Klymenko, S. ; Zitzelsberger, H. ; Unger, K.
Comparative global characterisation of microRNA-expression in radiation-associated and sporadic breast carcinomas.Selmansberger, M. ; Feuchtinger, A. ; Zurnadzhy, L. ; Höfig, I. ; Bogdanova, T. ; Walch, A.K. ; Unger, K. ; Zitzelsberger, H. ; Hess J.
CLIP2 as radiation biomarker in papillary thyroid carcinoma.Hess J. ; Gimenez-Aznar, I. ; Michna, A. ; Hieber, L. ; Braselmann, H. ; Schuettrumpf, L. ; Unger, K. ; Zangen, V. ; Klein, D. ; Jendrossek, V. ; Belka, C. ; Zitzelsberger, H. ; Lauber, K.
FANCA overexpression confers radioresistance to cells of head and neck squamous cell carcinoma.Summerer, I. ; Niyazi, M. ; Unger, K. ; Pitea, A. ; Zangen, V. ; Hess J. ; Atkinson, M.J. ; Belka, C. ; Mörtl, S. ; Zitzelsberger, H.
Changes in circulating microRNAs after radiochemotherapy in head and neck cancer patients.Buhmann, R. ; Stanglmaier, M. ; Hess J. ; Lindhofer, H. ; Peschel, C. ; Kolb, H.-J.
Immunotherapy with FBTA05 (Bi20), a trifunctional bispecific anti-CD3 x anti-CD20 antibody and donor lymphocyte infusion (DLI) in relapsed or refractory B-cell lymphoma after allogeneic stem cell transplantation: Study protocol of an investigator-driven, open-label, non-randomized, uncontrolled, dose-escalating phase I/II-trial.Hess J.
Molekulargenetische Veränderungen auf Chromosom 7q11 als strahlenspezifische Marker in papillären Schilddrüsenkarzinomen nach dem Reaktorunfall von Tschernobyl.Ruf, P. ; Schäfer, B. ; Eissler, N. ; Mocikat, R. ; Hess J. ; Plöscher, M. ; Wosch, S. ; Suckstorff, I. ; Zehetmeier, C. ; Lindhofer, H.
Ganglioside GD2-specific trifunctional surrogate antibody Surek demonstrates therapeutic activity in a mouse melanoma model.Heiliger, K.-J. ; Hess J. ; Vitagliano, D. ; Salerno, P. ; Braselmann, H. ; Salvatore, G. ; Ugolini, C. ; Summerer, I. ; Bogdanova, T. ; Unger, K. ; Thomas, G. ; Santoro, M. ; Zitzelsberger, H.
Novel candidate genes of thyroid tumourigenesis identified in Trk-T1 transgenic mice.Hess J. ; Thomas, G. ; Braselmann, H. ; Bauer, V. ; Bogdanova, T. ; Wienberg, J. ; Zitzelsberger, H. ; Unger, K.
Gain of chromosome band 7q11 in papillary thyroid carcinomas of young patients is associated with exposure to low-dose irradiation.