Mautner Lab
Our research focus is on the immune response against the Epstein-Barr virus (EBV), and EBV-associated disease. With a better understanding of how immunity against EBV is established, we seek to establish predictive markers for the development and novel strategies for the treatment of virus-associated disorders.
Our research focus is on the immune response against the Epstein-Barr virus (EBV), and EBV-associated disease. With a better understanding of how immunity against EBV is established, we seek to establish predictive markers for the development and novel strategies for the treatment of virus-associated disorders.
About our research
EBV is carried by the vast majority of the human population. Following primary infection, EBV persists lifelong in the human host. In most virus carriers, EBV is contained as asymptomatic infection by the immune system. However, EBV is an oncogenic virus and causes different types of tumors that account for 1 to 2% of all human cancers. Furthermore, EBV has been linked with the development of several autoimmune disorders, most notably multiple sclerosis. Why EBV infection remains asymptomatic in most virus carriers and causes various diseases in a subset of infected individuals is still incompletely understood.
Our scientists at Mautner Lab
Publications
Read more2022 Scientific Article in Cancers
T cells directed against the metastatic driver chondromodulin-1 in ewing sarcoma: Comparative engineering with CRISPR/Cas9 vs. retroviral gene transfer for adoptive transfer.
2022 Scientific Article in Frontiers in Immunology
Association between IgG responses against the nucleocapsid proteins of alphacoronaviruses and COVID-19 severity.
