CF-iPSC publication

2022 Scientific Article in Stem Cell Research Stem Cell Res. 61:102773 (2022)

Iuso, A. ; Zhang, F. ; Rusha, E. ; Campbell, B. ; Dorn, T. ; Zanuttigh, E. ; Haas, D. ; Anikster, Y. ; Lederer, G. ; Pertek, A. ; Nteli, P. ; Laugwitz, K.L. ; Moretti, A.

Generation of two human iPSC lines, HMGUi003-A and MRIi028-A, carrying pathogenic biallelic variants in the PPCS gene.

2022 Scientific Article in Scientific Reports Sci. Rep. 12:3100 (2022)

Zywitza, V. ; Rusha, E. ; Shaposhnikov, D. ; Ruiz-Orera, J. ; Telugu, N. ; Rishko, V. ; Hayashi, M. ; Michel, G. ; Wittler, L. ; Stejskal, J. ; Holtze, S. ; Göritz, F. ; Hermes, R. ; Wang, J. ; Izsvák, Z. ; Colleoni, S. ; Lazzari, G. ; Galli, C. ; Hildebrandt, T.B. ; Hayashi, K. ; Diecke, S. ; Drukker, M.

Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction.

2021 Scientific Article in The CRISPR Journal CRISPR J. 4, 178-190 (2021)

Eberherr, A.C. ; Maaske, A. ; Wolf, C. ; Giesert, F. ; Berutti, R. ; Rusha, E. ; Pertek, A. ; Kastlmeier, M.T. ; Voss, C. ; Plummer, M. ; Sayed, A. ; Graf, E. ; Effner, R. ; Volz, T. ; Drukker, M. ; Strom, T.M. ; Meitinger, T. ; Stöger, T. ; Buyx, A.M. ; Hagl, B. ; Renner, E.D.

Rescue of STAT3 function in hyper-IgE syndrome using adenine base editing.

2020 Scientific Article in BMC Biology BMC Biol. 18:42 (2020)

Grosch, M. ; Rusha, E. ; Ori, C. ; Truong, D.J.J. ; O'Neill, A.C. ; Pertek, A. ; Westmeyer, G.G. ; Drukker, M.

Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation.

2019 Scientific Article in Stem Cell Reports Stem Cell Rep. 12, 861-868 (2019)

Matheus, F. ; Rusha, E. ; Rehimi, R. ; Molitor, L. ; Pertek, A. ; Modic, M. ; Feederle, R. ; Flatley, A. ; Kremmer, E. ; Geerlof, A. ; Rishko, V. ; Rada-Iglesias, A. ; Drukker, M.

Pathological ASXL1 mutations and protein variants impair neural crest development.

2019 Scientific Article in Molecular Cell Mol. Cell 74, 951-965.e13 (2019)

Modic, M. ; Grosch, M. ; Rot, G. ; Schirge, S. ; Lepko, T. ; Yamazaki, T. ; Lee, F.C.Y. ; Rusha, E. ; Shaposhnikov, D. ; Palo, M. ; Merl-Pham, J. ; Cacchiarelli, D. ; Rogelj, B. ; Hauck, S.M. ; von Mering, C. ; Meissner, A. ; Lickert, H. ; Hirose, T. ; Ule, J. ; Drukker, M.

Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition.

2019 Scientific Article in Nature medicine Nat. Med. 25, 561–568 (2019)

Klaus, J. ; Kanton, S. ; Kyrousi, C. ; Ayo-Martin, A.C. ; Di Giaimo, R. ; Riesenberg, S. ; O'Neill, A.C. ; Camp, J.G. ; Tocco, C. ; Santel, M. ; Rusha, E. ; Drukker, M. ; Schroeder, M. ; Götz, M. ; Robertson, S.P. ; Treutlein, B. ; Cappello, S.

Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia.

2018 Scientific Article in Glia Glia 66, 413-427 (2018)

Kunze, C. ; Börner, K. ; Kienle, E. ; Orschmann, T. ; Rusha, E. ; Schneider, M. ; Radivojkov-Blagojevic, M. ; Drukker, M. ; Desbordes, S.C. ; Grimm, D. ; Brack-Werner, R.

Synthetic AAV/CRISPR vectors for blocking HIV-1 expression in persistently infected astrocytes.

2014 Scientific Article in Molecular Biotechnology : MB Online Mol. Biotechnol. 56, 697-713 (2014)

Pertek, A. ; Meier, F. ; Irmler, M. ; Beckers, J. ; Skylaki, S. ; Endele, M. ; Wurst, W. ; Prakash, N. ; Kühn, R.

Simple derivation of transgene-free iPS cells by a dual recombinase approach.

2013 Scientific Article in PLoS ONE PLoS ONE 8:e55170 (2013)

Merkl, C. ; Saalfrank, A. ; Riesen, N. ; Kühn, R. ; Pertek, A. ; Eser, S. ; Hardt, M.S. ; Kind, A. ; Saur, D. ; Wurst, W. ; Iglesias, A. ; Schnieke, A.

Publications