Molecular Obesity Research / Heiker-Lab
Our group ‘Molecular Obesity Research’ pursues several approaches to investigate protein, especially serpins and proteases, function in adipose tissue and obesity. We use our expertise in protein expression and purification to generate substantial amounts of these proteins and elucidate the structural characteristics and molecular mechanisms underlying their biologic activity. In parallel, we are dedicated to unravel their physiological function in health and disease using isolated cells, tissues and animal models.
Our group ‘Molecular Obesity Research’ pursues several approaches to investigate protein (e.g. serpin or protease) function in adipose tissue and obesity. We use our expertise in protein expression and purification to generate substantial amounts of these proteins and elucidate the structural characteristics and molecular mechanisms underlying their biologic activity. In parallel, we are dedicated to unravel their physiological function in health and disease using isolated cells, tissues and animal models.
Alumni of the Heiker Lab
- Lisa Christen, PhD (2020-2023)
- Sebastian Dommel, PostDoc (2022-2023)
- Aleix Ribas Latre, PostDoc (2020-2023)
- Hanna Scheffold B.Sc. (2022)
- Catherine Tindall, PhD (2017-2021)
- Sophie Rehme, M.Sc. (2021)
- Helen Broghammer, B.Sc. (2021)
- Sandra Kuhn, M.Sc. (2021)
- Nicolas Mytzka, M.Sc. (2020)
- Estelle Erkner, M.Sc. (2019)
- Benjamin Fritz, M.Sc. (2019)
- Lisa Volke, M.Sc. (2019)
Publications
Complete List of Publications of the Heiker Lab2023 Frontiers in Endocrinology (2023), 14:1146454
2022 Clinical and Translational Medicine (2022), 12:e1108
2018 Cell Mol Life Sci. 2018 Feb;75(4):727-742
2017 Mol Metab. 2017 Jun; 6(6): 482–493
2013 Cell Mol Life Sci. 2013; 70(14): 2569–2583