All publications
2022 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 116, 394-403 (2022)
Sources of dietary gluten in the first 2 years of life and associations with celiac disease autoimmunity and celiac disease in Swedish genetically predisposed children: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2022 Scientific Article in Trials Trials 23:414 (2022)
INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes.
2022 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 119, 765-770 (2022)
SARS-CoV-2 seroprevalence in preschool and school-age children.
2022 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 445-460 (2022)
Früherkennung und Prävention des Typ-1-Diabetes.
2022 Scientific Article in Diabetes Diabetes 71, 2632-2641 (2022)
Islet autoantibody levels differentiate progression trajectories in individuals with presymptomatic type 1 diabetes.
2022 Scientific Article in BMC Endocrine Disorders BMC Endocr. Disord. 22:19 (2022)
Is staff consistency important to parents' satisfaction in a longitudinal study of children at risk for type 1 diabetes: The TEDDY study.
2022 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 23, 1707-1716 (2022)
The emotional well-being of parents with children at genetic risk for type 1 diabetes before and during participation in the POInT-study.
2022 Review in Pediatric Diabetes Pediatr. Diabetes 23, 1175-1187 (2022)
ISPAD clinical practice consensus guidelines 2022: Stages of type 1 diabetes in children and adolescents.
2022 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 23, 1586-1593 (2022)
HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children.
2022 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, S98-S110 (2022)
Definition, Klassifikation, Diagnostik und Differenzialdiagnostik des Diabetes mellitus: Update 2022.
2022 Review in MMW - Fortschritte der Medizin MMW-Fortschr. Med. 164, 67-69 (2022)
Rolle der genetischen Prädisposition. Risiko für Typ-1-Diabetes auch bei Nachkommen erhöht?
2022 Scientific Article in JAMA: Journal of the American Medical Association JAMA 328, 1252-1255 (2022)
SARS-CoV-2 infections and presymptomatic type 1 diabetes autoimmunity in children and adolescents from Colorado, USA, and Bavaria, Germany.
2022 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, S215-S225 (2022)
Gestational diabetes mellitus (GDM), diagnosis, therapy and aftercare.
2022 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 10, 589-596 (2022)
Two-age islet-autoantibody screening for childhood type 1 diabetes: A prospective cohort study.
2022 Scientific Article in EBioMedicine EBioMedicine 82:104118 (2022)
A classification and regression tree analysis identifies subgroups of childhood type 1 diabetes.
2022 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 132:e162123 (2022)
Elevations in blood glucose before and after the appearance of islet autoantibodies in children.
2022 Scientific Article in Diabetologia Diabetologia 65, 93-104 (2022)
Progression likelihood score identifies substages of presymptomatic type 1 diabetes in childhood public health screening.
2022 Scientific Article in Diabetologia Diabetologia 66, 93-104 (2022)
Quantifying the utility of islet autoantibody levels in the prediction of type 1 diabetes in children.
2022 Diabetologia Diabetologia, DOI: 10.1007/s00125-022-05798-z (2022)
Correction to: Progression likelihood score identifies substages of presymptomatic type 1 diabetes in childhood public health screening.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 2342-2349 (2022)
Rising hemoglobin A1c in the nondiabetic range predicts progression of type 1 diabetes as well as oral glucose tolerance tests.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 2271-2281 (2022)
Predictors of the initiation of islet autoimmunity and progression to multiple autoantibodies and clinical diabetes: The TEDDY study.
2022 Scientific Article in Diabetes Aktuell Diabetes akt. 20, 116-123 (2022)
Typ-1-Diabetes bei Kindern früh erkennen und präventiv handeln. Die Fr1da-Studie.
2022 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 23, 714-720 (2022)
Autoantibodies against ATP4A are a feature of the abundant autoimmunity that develops in first-degree relatives of patients with type 1 diabetes.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, 2329-2338 (2022)
Integration of infant metabolite, genetic and islet autoimmunity signatures to predict type 1 diabetes by 6 years of age.
2022 Scientific Article in BMC Cancer BMC Cancer 22:386 (2022)
Invadopodia play a role in prostate cancer progression.
2022 Review in Diabetologie, Die Diabetologie 18, 758–768 (2022)
Molekulargenetische Diagnostik des Diabetes mellitus.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:4516 (2022)
Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study.
2022 Scientific Article in Nature Communications Nat. Commun. 13:3151 (2022)
Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: The TEDDY study.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 1822-1832 (2022)
Maternal dietary glycemic index and glycemic load in pregnancy and offspring cord blood DNA methylation.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 31, 3377–3391 (2022)
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, 1520-1528 (2022)
Childhood height growth rate association with the risk of islet autoimmunity and development of type 1 diabetes.
2022 Scientific Article in Environmental Research Environ. Res. 212:113503 (2022)
Association of long-term environmental exposures in pregnancy and early life with islet autoimmunity development in children in Bavaria, Germany.
2022 Scientific Article in Genome Medicine Genome Med. 14:51 (2022)
Breast cancer risks associated with missense variants in breast cancer susceptibility genes.
2022 Scientific Article in Acta Diabetologica Acta Diabetol. 59, 687-696 (2022)
Intra-lymphatic administration of GAD-alum in type 1 diabetes: Long-term follow-up and effect of a late booster dose (the DIAGNODE Extension trial).
2022 Scientific Article in iScience iScience 25:103680 (2022)
An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs.
2022 Scientific Article in Diabetologia Diabetologia 65, 1278-1290 (2022)
Insulin allergy: A diagnostic and therapeutic strategy based on a retrospective cohort and a case–control study.
2022 Review in Diabetes Diabetes 71, 610-623 (2022)
Screening for type 1 diabetes in the general population: A status report and perspective.
2022 Scientific Article in Nature Communications Nat. Commun. 13:1514 (2022)
Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 614-623 (2022)
Maternal glycemic dysregulation during pregnancy and neonatal blood DNA methylation: Meta-analyses of epigenome-wide association studies.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 837-844 (2022)
Costs of public health screening of children for presymptomatic type 1 diabetes in Bavaria, Germany.
2022 Nature medicine Nat. Med. 28:599 (2022)
Author Correction: A combined risk score enhances prediction of type 1 diabetes among susceptible children.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 624-633 (2022)
Heterogeneity of DKA incidence and age-specific clinical characteristics in children diagnosed with type 1 diabetes in the TEDDY Study.
2022 Scientific Article in Diabetes Diabetes 71, 566-577 (2022)
Cytotoxicity-related gene expression and chromatin accessibility define a subset of CD4+ T cells that mark progression to type 1 diabetes.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 160-168 (2022)
Islet autoantibody type-specific titer thresholds improve stratification of risk of progression to type 1 diabetes in children.
2022 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev.:e3500 (2022)
Immune response differs between intralymphatic or subcutaneous administration of GAD-alum in individuals with recent onset type 1 diabetes.
2022 Scientific Article in Epigenetics Epigenetics 17, 19-31 (2022)
Maternal haemoglobin levels in pregnancy and child DNA methylation: A study in the pregnancy and childhood epigenetics consortium.
2021 Scientific Article in AMIA Annual Symposium Proceedings AMIA Annu. Symp. Proc. 2021, 754-762 (2021)
Imputing longitudinal growth data in international pediatric studies: Does CDC reference suffice?
2021 Scientific Article in Breast Cancer Research Breast Cancer Res. 23:86 (2021)
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:19787 (2021)
Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.
2021 Scientific Article in Nature Nature 600, 720–726 (2021)
A hormone complex of FABP4 and nucleoside kinases regulates islet function.
2021 Scientific Article in BMJ Open BMJ Open 11:e052449 (2021)
Supplementation with Bifidobacterium longum subspecies infantis EVC001 for mitigation of type 1 diabetes autoimmunity: the GPPAD-SINT1A randomised controlled trial protocol.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0259629 (2021)
A new mathematical approach to improve the original dietary inflammatory index (DII) calculation.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S215-S225 (2021)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge-Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2021 Other: Opinion in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 369-371 (2021)
"A Pragmatic, Randomized Clinical Trial of Gestational Diabetes Screening"-eine interdisziplinäre Stellungnahme.
2021 Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 129, e1 (2021)
Correction: Gestational diabetes mellitus (GDM), diagnostics, therapy and follow-up care.
2021 Review in Med (N Y) Med. 2, 1120-1137 (2021)
100 Years of insulin: Lifesaver, immune target, and potential remedy for prevention.
2021 Scientific Article in Frontiers in Nutrition Front. Nutr. 8:720041 (2021)
25(OH)D levels in infancy is associated with celiac disease autoimmunity in at-risk children: A case-control study.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:767012 (2021)
Editorial: Footprints of immune cells in the type 1 diabetic pancreas.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202101013 (2021)
Functional and metabolic fitness of human CD4+ T lymphocytes during metabolic stress.
2021 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-021-05523-2 (2021)
Simplifying prediction of disease progression in pre-symptomatic type 1 diabetes using a single blood sample.
2021 Scientific Article in Diabetologia Diabetologia 64, 2247-2257 (2021)
Characteristics of children diagnosed with type 1 diabetes before vs after 6 years of age in the TEDDY cohort study.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 367-372 (2021)
Diabetic ketoacidosis at manifestation of type 1 diabetes in childhood and adolescence.
2021 Review in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd. 169, 922–929 (2021)
Nicht immer Typ 1 – seltene Diabetesformen bei Kindern.
2021 Scientific Article in Frontiers in Molecular Biosciences Front. Mol. Biosci. 8:689799 (2021)
Whole-slide image analysis of human pancreas samples to elucidate the immunopathogenesis of type 1 diabetes using the QuPath software.
2021 Review in Frontiers in Immunology Front. Immunol. 12:683091 (2021)
Means, motive, and opportunity: Do non-islet-reactive infiltrating T cells contribute to autoimmunity in type 1 diabetes?
2021 Scientific Article in Diabetes Care Diabetes Care 44, 2269-2276 (2021)
Islet autoimmunity and HLA markers of presymptomatic and clinical type 1 diabetes: Joint analyses of prospective cohort studies in Finland, Germany, Sweden, and the U.S.
2021 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 108, 1190-1203 (2021)
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 1992-1999 (2021)
Epigenome-wide association study reveals methylation loci associated with offspring gestational diabetes mellitus exposure and maternal methylome.
2021 Review in Frontiers in Immunology Front. Immunol. 12:667989 (2021)
Neoepitopes in type 1 diabetes: Etiological insights, biomarkers and therapeutic targets.
2021 Review in Diabetes Diabetes 70, 1038-1050 (2021)
Altered β-cell prohormone processing and secretion in type 1 diabetes.
2021 Scientific Article in Frontiers in Immunology Front. Immunol. 12:656451 (2021)
Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in type 1 diabetes.
2021 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 114, 134-142 (2021)
Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2021 Review in Diabetologie, Die Diabetologie 17, 538–548 (2021)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge.Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2021 Letter to the Editor in Med (N Y) Med. 2, 571-572 (2021)
A public health antibody screening indicates a marked increase of SARS-CoV-2 exposure rate in children during the second wave.
2021 Scientific Article in Science Translational Medicine Sci. Transl. Med. 13:eabd5666 (2021)
Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression.
2021 Scientific Article in Diabetologia Diabetologia 64, 1604-1612 (2021)
Maternal food consumption during late pregnancy and offspring risk of islet autoimmunity and type 1 diabetes.
2021 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 129, 1, S9-S19 (2021)
Gestational diabetes mellitus (GDM), diagnostics, therapy and follow-up care. Practice recommendation - Summary of the S3 guideline (AWMF register number: 057–008).
2021 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 22, 717-728 (2021)
Parental monitoring for type 1 diabetes in genetically at-risk young children: The TEDDY study.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabd6527 (2021)
Islet expression of type I interferon response sensors is associated with immune infiltration and viral infection in type 1 diabetes.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 2260-2268 (2021)
An age-related exponential decline in the risk of multiple islet autoantibody seroconversion during childhood.
2021 Nature Nature 592:E8 (2021)
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (Nature, (2020), 587, 7834, (377-386), 10.1038/s41586-020-2715-9).
2021 Letter to the Editor in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 105-105 (2021)
Kommentar.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:3627 (2021)
Children's erythrocyte fatty acids are associated with the risk of islet autoimmunity.
2021 Scientific Article in Diabetologia Diabetologia 64, 1079-1092 (2021)
Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial.
2021 Scientific Article in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd. 169, 451–460 (2021)
Kann die Ketoacidose bei pädiatrischen Patienten mit Manifestation eines Diabetes mellitus Typ 1 vermieden werden? Lehren aus der COVID-19-Pandemie.
2021 Scientific Article in Diabetologia Diabetologia 64, 591-602 (2021)
First-appearing islet autoantibodies for type 1 diabetes in young children: Maternal life events during pregnancy and the child’s genetic risk.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 63-69 (2021)
Neue Klassifikation des Diabetes mellitus – Anforderungen an Labormessgrößen.
2021 Scientific Article in Diabetes Diabetes 70, 752-758 (2021)
One in ten CD8+ cells in the pancreas of living individuals with recent onset type 1 diabetes recognizes the preproinsulin epitope PPI15-24.
2021 Scientific Article in Diabetes Diabetes 70, 282-292 (2021)
Plasma metabolome and circulating vitamins stratified onset age of an initial islet autoantibody and progression to type 1 diabetes: The TEDDY Study.
2021 Scientific Article in Med (N Y) Med. 2, 149-163.e4 (2021)
Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children.
2021 Editorial in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 17, 73–74 (2021)
Shortening the paths to type 1 diabetes mellitus prevention.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S181-S181 (2020)
Optimal ages for screening for type 1 diabetes risk in children.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S157-S157 (2020)
Presence of markers associated with viral infections in the pancreas before and after onset of type 1 diabetes.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S26-S27 (2020)
Long-term follow-up study of type 1 diabetes patients previously treated with IMCY-0098 or placebo in young adults with recent-onset type 1 diabetes.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S101-S102 (2020)
Visualising heterogeneous islet autoantibody trajectories of children who develope type 1 diabetes from multi-site birth cohort studies.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S159-S159 (2020)
A visual analytics method to explore the evolution of autoantibodies during progression to type 1 diabetes in multi-site birth cohort studies.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S160-S160 (2020)
Heterogeneous islet autoantibody evolution trajectories in multi-site birth cohort studies.
2020 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:9647 (2020)
Intergenerational metabolomic analysis of mothers with a history of gestational diabetes mellitus and their offspring.
2020 Scientific Article in Nature metabolism Nat. Metab. 2, 1021-1024 (2020)
Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: A case report.
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S101-S111 (2020)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge – Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2020 Scientific Article in Science Advances Sci. Adv. 6:eabc5586 (2020)
The healthy exocrine pancreas contains preproinsulin-specific CD8 T cells that attack islets in type 1 diabetes.
2020 Scientific Article in Frontiers in Immunology Front. Immunol. 11:564921 (2020)
Glutamic acid decarboxylase injection into lymph nodes: Beta cell function and immune responses in recent onset type 1 diabetes patients.
2020 Review in Nature Nature 587, 377–386 (2020)
LifeTime and improving European healthcare through cell-based interceptive medicine.
2020 Review in Diabetologie, Die Diabetologie 16, 654-661 (2020)
Typ-1-Diabetes: Früherkennung und Ansätze zur Prävention.Update 2020.
2020 Scientific Article in Nature medicine Nat. Med. 26, 1247-1255 (2020)
A combined risk score enhances prediction of type 1 diabetes among susceptible children.
2020 Scientific Article in Diabetes Care Diabetes Care 43, 2066-2073 (2020)
Hierarchical order of distinct autoantibody spreading and progression to type 1 diabetes in the Teddy study.
2020 Letter to the Editor in Diabetologia Diabetologia, DOI: 10.1007/s00125-020-05175-8 (2020)
Why is the presence of autoantibodies against GAD associated with a relatively slow progression to clinical diabetes?
2020 Review in Diabetologie, Die Diabetologie 16, 362-372 (2020)
Gestational diabetes mellitus (GDM), diagnostics, therapy and aftercare: Practice Recommendation—Abstract of the S3 Guideline (AWMF Register Number: 057-008).
2020 Scientific Article in European Journal of Immunology Eur. J. Immunol. 50, 903-905 (2020)
Soluble IL-7 receptor alpha concentration in cord blood is linked to sex and maternal diabetes, but not with subsequent development of type 1 diabetes.
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 105, e2192–e2206 (2020)
Randomized 52-week phase 2 trial of albiglutide vs placebo in adult patients with newly diagnosed type 1 diabetes.
2020 Scientific Article in JAMA: Journal of the American Medical Association JAMA 323, 339-351 (2020)
Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany.
2020 Scientific Article in Diabetes Diabetes 69, 465-476 (2020)
Longitudinal metabolome-wide signals prior to the appearance of a first islet autoantibody in children participating in the TEDDY Study.
2020 Scientific Article in Diabetes Care Diabetes Care 43, 556-562 (2020)
Distinct growth phases in early life associated with the risk of type 1 diabetes: The TEDDY study.
2020 Scientific Article in Diabetes Diabetes 69, 661-669 (2020)
Maternal type 1 diabetes reduces autoantigen-responsive CD4(+) T cells in Offspring.
2020 Scientific Article in Journal of Autoimmunity J. Autoimmun. 107:102378 (2020)
Human herpesvirus-6 is present at higher levels in the pancreatic tissues of donors with type 1 diabetes.
2020 Scientific Article in Diabetologia Diabetologia 63, 278-286 (2020)
Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: The TEDDY study.
2020 Review in Biotechnology Advances Biotechnol. Adv. 39:107359 (2020)
Harmonization of immunoassays for biomarkers in diabetes mellitus.
2019 Scientific Article in Nature Communications Nat. Commun. 10:5697 (2019)
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes.
2019 Scientific Article in Nature medicine Nat. Med. 25, 1865-1872 (2019)
Prospective virome analyses in young children at increased genetic risk for type 1 diabetes.
2019 Scientific Article in Gut (eGut) Gut 69, 1416–1422 (2019)
Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: The TEDDY study.
2019 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 14, S196-S206 (2019)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge. Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2019 Scientific Article in Scientific Reports Sci. Rep. 9:14819 (2019)
Metabolite-related dietary patterns and the development of islet autoimmunity.
2019 Meeting abstract in Diabetologia Diabetologia 62, S203-S203 (2019)
Enterovirus as triggers of disease? New insights from autoantibody positive and type 1 diabetic nPOD donors.
2019 Meeting abstract in Diabetologia Diabetologia 62, S352-S353 (2019)
Phase Ib clinical trial of IMCY-0098 in young adults with recent-onsent type 1 diabetes.
2019 Scientific Article in Clinical Chemistry Clin. Chem. 65, 1141-1152 (2019)
Islet autoantibody standardization program 2018 workshop: Interlaboratory comparison of glutamic acid decarboxylase autoantibody assay performance.
2019 Scientific Article in Stress and health Stress and Health 35, 289-303 (2019)
The association between stressful life events and respiratory infections during the first 4 years of life: The Environmental Determinants of Diabetes in the Young study.
2019 Scientific Article in JAMA: Journal of the American Medical Association JAMA 322, 514-523 (2019)
Association of gluten intake during the first 5 years of Llfe with incidence of celiac disease autoimmunity and celiac disease among children at increased risk.
2019 Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 62, 1276-1277 (2019)
Ethical consideration of studies involving human subjects outside the regulatory framework: Not mandatory, but of high relevance (vol 62, pg 722, 2019).
2019 Scientific Article in Nutrients Nutrients 11:1790 (2019)
Early probiotic supplementation and the risk of celiac disease in children at genetic risk.
2019 Review in Clinical & Experimental Immunology Clin. Exp. Immunol. 198, 294-305 (2019)
Birth and coming of age of islet autoantibodies.
2019 Scientific Article in International Journal of Epidemiology Int. J. Epidemiol. 48, 1051-1051K (2019)
Cohort Profile: The DynaHEALTH consortium - a European consortium for a life-course bio-psychosocial model of healthy ageing of glucose homeostasis.
2019 Scientific Article in BMC Medicine BMC Med. 17:125 (2019)
Landmark models to define the age-adjusted risk of developing stage 1 type 1 diabetes across childhood and adolescence.
2019 Scientific Article in BMJ Open BMJ Open 9:e028578 (2019)
Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol.
2019 Scientific Article in Diabetes Care Diabetes Care 42, 1684-1691 (2019)
Age, HLA, and sex define a marked risk of organ-specific autoimmunity in first-degree relatives of patients with type 1 diabetes.
2019 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 20, 720-727 (2019)
Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials-GPPAD-02 study design and first results.
2019 Editorial in Diabetologie, Die Diabetologie 15, 333-343 (2019)
Gestational Diabetes mellitus (GDM), Diagnostics, Therapy and Aftercare Practice Recommendation - Abstract of the S3 Guideline (AWMF Register Number: 057-008).
2019 Scientific Article in Diabetes Care Diabetes Care 42, 1051-1060 (2019)
Predicting islet cell autoimmunity and type 1 diabetes: An 8-year TEDDY study progress report.
2019 Review in Diabetes Aktuell Diabetes akt. 17, 110-112 (2019)
Infektionen in der Schwangerschaft und frühen Kindheit. Risiko für Betazell-Autoimmunität und Typ-1-Diabetes?
2019 Review in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 62, 722-728 (2019)
Ethical consideration of studies involving human subjects outside the regulatory framework: not mandatory, but of high relevance.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:6250 (2019)
Common patterns of gene regulation associated with Cesarean section and the development of islet autoimmunity - indications of immune cell activation.
2019 Scientific Article in Diabetologia Diabetologia 62, 805-810 (2019)
Cytoplasmic ends of tetraspanin 7 harbour epitopes recognised by autoantibodies in type 1 diabetes.
2019 Scientific Article in Arthritis & Rheumatology Arthritis Rheum. 71, 817-828 (2019)
Association of dendritic cell signatures with autoimmune inflammation revealed by single-cell profiling.
2019 Editorial in Diabetes, Stoffwechsel und Herz Diabetes Stoffwechs. Herz 28, 33-35 (2019)
Infantile vitamin-D-levels determine the risk for type 1-diabetes.
2019 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 20, 263-270 (2019)
Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children.
2019 Scientific Article in Diabetes Diabetes 68, 847-857 (2019)
Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families.
2019 Other: Opinion in The lancet child & adolescent health Lancet Child Adolesc. Health 3, 288-290 (2019)
Screening for asymptomatic β-cell autoimmunity in young children.
2019 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 20, 86-92 (2019)
Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study.
2019 Scientific Article in Acta Paediatrica Acta Paediatr. 108, 940-944 (2019)
Blood draws up to 3% of blood volume in clinical trials are safe in children.
2019 Scientific Article in Diabetic Medicine Diabetic Med. 36, 366-375 (2019)
Physical activity is associated with lower insulin and C-peptide during glucose challenge in children and adolescents with family background of diabetes.
2018 Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 13, E1 (2018)
Erratum: Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge:: Praxisempfehlung - Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008) (Diabetologie und Stoffwechsel (2018) 13:Suppl 2 (S174-S184) DOI: 10.1055/a-0598-3468).
2018 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 19, 1025-1033 (2018)
Family adjustment to diabetes diagnosis in children: Can participation in a study on type 1 diabetes genetic risk be helpful?
2018 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 17, 1824-1836 (2018)
Quality control analysis in real-time (QC-ART): A tool for real-time quality control assessment of mass spectrometry-based proteomics data.
2018 Review in Geburtshilfe und Frauenheilkunde Geburtsh. u. Frauenheilk. 78, 1219-1231 (2018)
Gestational Diabetes Mellitus (GDM) - Diagnosis, Treatment and Follow-Up. Guideline of the DDG and DGGG (S3 Level, AWMF Registry Number 057/008, February 2018).
2018 Meeting abstract in Transplant international Transpl. Int. 31, 32-32 (2018)
Effects of MTOR-IS on malignancy and survival following renal transplantation: A systematic review and meta-analysis of randomized trials with a minimum follow-up of 24 months.
2018 Scientific Article in Diabetes Diabetes 67, 2329-2336 (2018)
Reduction in white blood cell, neutrophil, and red blood cell counts related to sex, HLA, and islet autoantibodies in Swedish TEDDY children at increased risk for type 1 diabetes.
2018 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 13, S174-S184 (2018)
Gestational diabetes mellitus (GDM), diagnosis, therapy and follow-up.
2018 Scientific Article in Nature Nature 562, 589-594 (2018)
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study.
2018 Scientific Article in Nature Nature 562, 583-588 (2018)
Temporal development of the gut microbiome in early childhood from the TEDDY study.
2018 Review in Current Diabetes Reports Curr. Diab. Rep. 18:136 (2018)
The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update.
2018 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 41, 140-141 (2018)
The EUTOS long-term survival (ELTS) score is superior to the Sokal score for prognosis of probabilities of dying of chronicphase chronic myeloid leukaemia.
2018 Scientific Article in Statistics in Medicine Stat. Med. 37, 4771-4788 (2018)
Nonlinear association structures in flexible Bayesian additive joint models.
2018 Review in Clinical & Experimental Immunology Clin. Exp. Immunol. 195, 15-24 (2018)
Enterovirus infection and type 1 diabetes: Unraveling the crime scene.
2018 Scientific Article in Diabetes Diabetes 68, 119-130 (2018)
Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children.
2018 Scientific Article in Journal of Medical Genetics J. Med. Genet. 56, 602-605 (2018)
Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: Results from the prospective TEDDY study.
2018 Review in Current Diabetes Reports Curr. Diab. Rep. 18:124 (2018)
Pancreas pathology during the natural history of type 1 diabetes.
2018 Scientific Article in PLoS ONE PLoS ONE 13:e0201959 (2018)
Molecular epidemiology of enteroviruses in young children at increased risk of type 1 diabetes.
2018 Scientific Article in Obesity Obesity 26, 1457-1466 (2018)
Associations of maternal diabetes during pregnancy with overweight in offspring: Results from the prospective TEDDY study.
2018 Scientific Article in Journal of Public Mental Health J. Public Health, DOI: 10.1007/s10389-018-0981-x (2018)
Feasibility and organization of a population-based screening for pre-symptomatic type 1 diabetes in children – Evaluation of the Fr1da study.
2018 Review in Diabetologia Diabetologia 61, 2252-2258 (2018)
Immunological biomarkers for the development and progression of type 1 diabetes.
2018 Review in Current Diabetes Reports Curr. Diab. Rep. 18:106 (2018)
Enteroviral infections as a trigger for type 1 diabetes.
2018 Scientific Article in Journal of Immunological Methods J. Immunol. Methods 463, 54-60 (2018)
CD4+ T cell activation, function, and metabolism are inhibited by low concentrations of DMSO.
2018 Meeting abstract in Allergy Allergy 73, 200-200 (2018)
Potential of upper airway mediators as biomarkers for asthmatic lung.
2018 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 19, 1238-1242 (2018)
Fasting hypoglycemia is associated with disease progression in presymptomatic early stage type 1 diabetes.
2018 Scientific Article in Contemporary clinical trials communications Contemp. Clin. Trails Comm. 11, 170-173 (2018)
Recruiting young pre-symptomatic children for a clinical trial in type 1 diabetes: Insights from the Fr1da insulin intervention study.
2018 Scientific Article in Diabetes Aktuell Diabetes akt. 16, 52-54 (2018)
Neue Studie zur Prävention von Typ-1-Diabetes.
2018 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev. 34:e3049 (2018)
Regional differences in type 2 diabetes treatment and outcomes in Germany-An analysis of the German DPV and DIVE registries.
2018 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 19, 20-27 (2018)
ISPAD Clinical Practice Consensus Guidelines 2018: Stages of type 1 diabetes in children and adolescents.
2018 Scientific Article in Diabetologia Diabetologia 61, 2319–2332 (2018)
Associations of maternal type 1 diabetes with childhood adiposity and metabolic health in the offspring: A prospective cohort study.
2018 Scientific Article in Clinical Immunology Clin. Immunol. 194, 87-91 (2018)
Novel minor HLA DR associated antigens in type 1 diabetes.
2018 Scientific Article in Journal of Diabetes Research J. Diabetes Res. 2018, 9391845 (2018)
Intralymphatic glutamic acid decarboxylase (GAD)-alum administration induced Th2-like specific immunomodulation in responder patients: a pilot clinical trial in type 1 diabetes.
2018 Scientific Article in Diabetologie, Die Diabetologie 14, 231-233 (2018)
Behandlung des Typ-1-Diabetes im Frühstadium: eine Kasuistik.
2018 Editorial in Diabetologie, Die Diabetologie 14, 212-213 (2018)
Früherkennung und präventive Behandlung des Typ-1-Diabetes.
2018 Review in Diabetologie, Die Diabetologie 14, 221-223 (2018)
Evaluation of the Fr1da screening: From an epidemiological perspective.
2018 Review in Diabetologie, Die Diabetologie 14, 240-244 (2018)
Früherkennung und Primärprävention des Typ-1-Diabetes: „Global Platform for the Prevention of Autoimmune Diabetes“ (GPPAD).
2018 Review in Diabetologie, Die Diabetologie 14, 234-239 (2018)
Typ-1-Diabetes im asymptomatischen Frühstadium: Orales Insulin zur präventiven Behandlung.
2018 Review in Diabetologie, Die Diabetologie 14, 214-220 (2018)
Früherkennung des Typ-1-Diabetes in der Fr1da-Studie: Diagnosestellung im asymptomatischen Stadium.
2018 Scientific Article in Diabetologia Diabetologia 61, 1644-1649 (2018)
Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12.
2018 Scientific Article in Acta Diabetologica Acta Diabetol. 55, 881-884 (2018)
Searching peripheral blood mononuclear cells of children with viral respiratory tract infections preceding islet autoimmunity for viruses by high-throughput sequencing.
2018 Scientific Article in Maternal & Child Nutrition Matern. Child Nutr. 14:e12611 (2018)
Milk feeding and first complementary foods during the first year of life in the TEDDY study.
2018 Scientific Article in International Journal of Obesity Int. J. Obes. 42, 1249-1264 (2018)
Maternal smoking during pregnancy and offspring overweight: Is there a dose-response relationship? An individual patient data meta-analysis.
2018 Review in Medizinische Monatsschrift für Pharmazeuten Med. Monatsschr. Pharm. 41, 105-109 (2018)
Immune preventive approaches for type-1-diabetes.
2018 Scientific Article in PLoS ONE PLoS ONE 13:e0194975 (2018)
Effects of mTOR-Is on malignancy and survival following renal transplantation: A systematic review and meta-analysis of randomized trials with a minimum follow-up of 24 months.
2018 Scientific Article in PLoS Medicine PLoS Med. 15:e1002548 (2018)
Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.
2018 Scientific Article in Diabetic Medicine Diabetic Med. 35, 1420-1424 (2018)
No further improvement in pregnancy-related outcomes in the offspring of mothers with pre-gestational diabetes in Bavaria, Germany, between 2001 and 2016.
2018 Scientific Article in Diabetic Medicine Diabetic Med. 35, 954-963 (2018)
The first 142 amino acids of glutamate decarboxylase do not contribute to epitopes recognized by autoantibodies associated with Type 1 diabetes.
2018 Scientific Article in Diabetologia Diabetologia 61, 1484–1490 (2018)
Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: The SNAIL study.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 9, 168-175 (2018)
Efficacy of vildagliptin for prevention of postpartum diabetes in women with a recent history of insulin-requiring gestational diabetes: A phase II, randomized, double-blind, placebo-controlled study.
2018 Scientific Article in JCI insight JCI insight 3:e98212 (2018)
A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes.
2018 Scientific Article in Diabetes Care Diabetes Care 41, 522-530 (2018)
Early infant diet and islet autoimmunity in the TEDDY Study.
2018 Scientific Article in Journal of Autoimmunity J. Autoimmun. 89, 90-100 (2018)
Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort.
2018 Scientific Article in Diabetes Diabetes 67, 146-154 (2018)
Plasma 25-hydroxyvitamin D concentration and risk of islet autoimmunity.
2018 Scientific Article in Acta Diabetologica Acta Diabetol. 55, 263–270 (2018)
A novel LIPS assay for insulin autoantibodies.
2018 Scientific Article in Journal of Autoimmunity J. Autoimmun. 89, 63-74 (2018)
Allele-specific methylation of type 1 diabetes susceptibility genes.
2018 Scientific Article in Clinical Nutrition Clin. Nutr. 37, 2246-2251 (2018)
10 patients, 10 years - Long term follow-up of cardiovascular risk factors in Glut1 deficiency treated with ketogenic diet therapies: A prospective, multicenter case series.
2018 Scientific Article in Journal of Autoimmunity J. Autoimmun. 86, 93-103 (2018)
Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident beta-cell autoantibodies.
2018 Scientific Article in Wiener medizinische Wochenschrift Wien. Med. Wochenschr. 168, 415–422 (2018)
Welche Patienten aus der Routinebetreuung verwenden das neue Insulin-Analogon Glargin U300 im Vergleich zu Patienten mit Glargin U100? Eine multizentrische Analyse von 14.123 Patienten mit Insulin Glargin aus den Diabetesregistern DPV und DIVE.
2018 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 19, 277-283 (2018)
Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young.
2017 Diabetes Diabetes 66, e10-e11 (2017)
Response to comment on Rodriguez-Calvo et al. Increase in pancreatic proinsulin and preservation of β-cell mass in autoantibody-positive donors prior to type 1 diabetes onset. Diabetes 2017;66:1334–1345.
2017 Scientific Article in Pediatrics Pediatrics 139:e20162848 (2017)
Psychological manifestations of celiac disease autoimmunity in young children.
2017 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 5, 864-876 (2017)
Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial.
2017 Scientific Article in JAMA Pediatrics JAMA Pediatr. 171, 1217-1225 (2017)
Association between early-life antibiotic use and the risk of islet or celiac disease autoimmunity.
2017 Editorial in Geburtshilfe und Frauenheilkunde Geburtsh. u. Frauenheilk. 77, 1151-1153 (2017)
New study on the prevention of type-1-diabetes.
2017 Scientific Article in Clinical Immunology Clin. Immunol. 188, 23-30 (2017)
GM-CSF producing autoreactive CD4(+) T cells in type 1 diabetes.
2017 Scientific Article in Journal of Proteome Research J. Proteome Res. 17, 618-634 (2017)
Proteomic landscape of patient-derived CD4+T cells in recent-onset type 1 diabetes.
2017 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 18, 794-802 (2017)
Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls.
2017 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 49, 892-898 (2017)
Thymus growth and fetal immune responses in diabetic pregnancies.
2017 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 50, 44-49 (2017)
Screening for type 1 diabetes risk in newborns: The Freder1k pilot study in Saxony.
München, Ludwig-Maximilians-Universität, Fakultät für Mathematik, Informatik und Statistik, Diss., 2017, 166 S.
Flexible Bayesian joint models for longitudinal biomarkers and time-to-event outcomes with applications to type 1 diabetes research.
2017 Diabetologia Diabetologia 61, 254-254 (2017)
Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: The TEDDY study.
2017 Scientific Article in Journal of Food Composition and Analysis J. Food Compos. Anal. 63, 79-88 (2017)
Development of a harmonized food grouping system for between-country comparisons in the TEDDY Study.
2017 Scientific Article in Diabetologia Diabetologia 61, 193–202 (2017)
Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children.
2017 Scientific Article in Pediatrics Pediatrics 140, DOI: 10.1542/peds.2017-1305 (2017)
Co-occurrence of type 1 diabetes and celiac disease autoimmunity.
2017 Scientific Article in Diabetologia Diabetologia 61, 117-129 (2017)
Metabolite ratios as potential biomarkers for type 2 diabetes: A DIRECT study.
2017 Scientific Article in European Journal of Clinical Nutrition Eur. J. Clin. Nutr. 71, 1449-1454 (2017)
Vitamin D and probiotics supplement use in young children with genetic risk for type 1 diabetes.
2017 Scientific Article in Diabetes Diabetes 66, 3122-3129 (2017)
The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history to the progression from multiple autoantibodies to type 1 diabetes: A TEDDY Study Report.
2017 Scientific Article in Pediatric obesity Pediatr. Obes. 12, 1, 125-129 (2017)
The relationship between breast milk leptin and adiponectin with child body composition from 3 to 5 years: A follow-up study.
2017 Scientific Article in Acta Diabetologica Acta Diabetol. 54, 1009–1017 (2017)
Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: Results from the TEDDY study.
2017 Scientific Article in Cell Metabolism Cell Metab. 26, 475-492.e7 (2017)
A Stat6/Pten axis links regulatory T cells with adipose tissue function.
2017 Letter to the Editor in Diabetes Diabetes 66, e10-e11 (2017)
Response to comment on Rodriguez-Calvo et al. Increase in pancreatic proinsulin and preservation of β-cell mass in autoantibody-positive donors prior to type 1 diabetes onset. diabetes 2017;66:1334-1345.
2017 Scientific Article in Diabetes Care Diabetes Care 40, 1167-1172 (2017)
My child is islet autoantibody positive: Impact on parental anxiety.
2017 Scientific Article in Diabetes Care Diabetes Care 40, 1194-1202 (2017)
Genetic and environmental interactions modify the risk of diabetes-related autoimmunity by 6 years of age: The TEDDY Study.
2017 Scientific Article in Diabetologia Diabetologia 60, 1931-1940 (2017)
Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: The TEDDY study.
2017 Scientific Article in Biometrical Journal Biom. J. 59, 1144-1165 (2017)
Flexible Bayesian additive joint models with an application to type 1 diabetes research.
2017 Scientific Article in American Journal of Epidemiology Am. J. Epidemiol. 186, 1277-1280 (2017)
Infections in early Life and development of celiac disease.
2017 Scientific Article in Journal of Pediatric Gastroenterology and Nutrition J. Pediatr. Gastroenterol. Nutr. 66, 417-424 (2017)
Cesarean section on the risk of celiac disease in the offspring: The Teddy Study.
2017 Scientific Article in Pediatric Research Pediatr. Res. 81, 745-751 (2017)
Cord blood and child plasma adiponectin levels in relation to childhood obesity risk and fat distribution up to 5 y.
2017 Letter to the Editor in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 13, 492-492 (2017)
β-Cell mass versus function in type 1 diabetes mellitus: truth or dare?
2017 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 12, 184-185 (2017)
Eine seltene Ursache für eine hyperinsulinämische Hypoglykämie.
2017 Scientific Article in Obesity Obesity 25, 1435-1441 (2017)
Intake of energy and protein is associated with overweight risk at age 5.5 years: Results from the prospective TEDDY study.
2017 Scientific Article in Developmental psychobiology Dev. Psychobiol. 59, 658-667 (2017)
The feasibility of salivary sample collection in an international pediatric cohort: The the TEDDY study.
2017 Scientific Article in Diabetologie, Die Diabetologie 13, 244-247 (2017)
Mischformen und Überlappung des Typ-1- und des Typ-2-Diabetes. Limitationen individueller Therapieoptionen durch die bestehende Disease-Management-Programm-Systematik.
2017 Scientific Article in BMC Pediatrics BMC Pediatr. 17:127 (2017)
Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity.
2017 Scientific Article in Clinical Gastroenterology and Hepatology Clin. Gastroenterol. Hepatol. 15, 694-702 (2017)
Factors that increase risk of celiac disease autoimmunity after a gastrointestinal infection in early life.
2017 Scientific Article in Nutrients Nutrients 9:E48 (2017)
Diet quality during infancy and early childhood in children with and without risk of type 1 diabetes: A DEDIPAC Study.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:44661 (2017)
CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.
In: (Proteomic Forum 2017, 2-5 April 2017, Potsdam). 2017. 119-120
The proteomic landscape of patient-derived CD4+ T cells in recent-onset type 1 diabetes.
2017 Scientific Article in British Journal of Nutrition Br. J. Nutr. 117, 466-472 (2017)
Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2017 Scientific Article in Vaccine Vaccine 35, 1735-1741 (2017)
Vaccinations in early life are not associated with development of islet autoimmunity in type 1 diabetes high-risk children: Results from prospective cohort data.
2017 Scientific Article in Science Translational Medicine Sci. Transl. Med. 9:eaaf8848 (2017)
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity.
2017 Scientific Article in Diabetologia Diabetologia 60, 35-38 (2017)
Rebranding asymptomatic type 1 diabetes: The case for autoimmune beta cell disorder as a pathological and diagnostic entity.
2017 Other: Opinion in JAMA Pediatrics JAMA Pediatr. 171, 93 (2017)
Miscalculation and errors in numbers reported in table.
2017 Scientific Article in Diabetes Care Diabetes Care 40, 398-404 (2017)
First infant formula type and risk of islet autoimmunity in the environmental determinants of diabetes in the young (TEDDY) study.
2017 Scientific Article in Diabetologia Diabetologia 60, 287-295 (2017)
Peptide serum markers in islet autoantibody-positive children.
2017 Review in Pediatric Diabetes Pediatr. Diabetes 18, 103-110 (2017)
Associations of growth patterns and islet autoimmunity in children with increased risk for type 1 diabetes: A functional analysis approach.
2016 Meeting abstract in Diabetologia Diabetologia 59, S550-S550 (2016)
Are recommended goals for secondary prevention of myocardial infarction or stroke achieved in real life? A German/Austrian DPV analysis of 29,325 patients with type 2 diabetes.
2016 Meeting abstract in Diabetologia Diabetologia 59, S187-S187 (2016)
Lactation is associated with altered metabolomic signatures in women with gestational diabetes.
2016 Meeting abstract in Diabetologia Diabetologia 59, S142-S143 (2016)
A metabolite ratio associates with measures of insulin secretion and altered risk of type 2 diabetes; a DIRECT study.
2016 Scientific Article in Journal of empirical research on human research ethics J. Empir. Res. Hum. Res. Ethics 11, 106-114 (2016)
Parental estimation of their child's increased type 1 diabetes risk during the first 2 years of participation in an international observational study: Results from the TEDDY study.
2016 Scientific Article in BMJ Open BMJ Open 6:e013835 (2016)
Time-saving screening for diabetes in patients with coronary artery disease: A report from EUROASPIRE IV.
2016 Scientific Article in Diabetes Diabetes 65, 3233-3239 (2016)
Type 1 diabetes prevention: A goal dependent on accepting a diagnosis of an asymptomatic disease.
2016 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 113, E6659-E6668 (2016)
miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.
2016 Scientific Article in MMW - Fortschritte der Medizin MMW-Fortschr. Med. 158, 65-67 (2016)
[Early diagnosis, early care - "Fr1da" screening of children for type 1 diabetes].
München, Technische Universität, Fakultät für Medizin, Diss., 2016, 123 S.
Integrative analysis of microRNA and mRNA expression profiles in osteosarcoma cell lines.
2016 Editorial in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd. 164, 639-641 (2016)
Fr1da-insulin-intervention study.Treatment of beta cell-autoimmunity by antigen-desensitization.
2016 Scientific Article in BMC Pregnancy and Childbirth BMC Pregnancy Childbirth 16:266 (2016)
Does charge-free screening improve detection of gestational diabetes in women from deprived areas: A cross-sectional study.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:32899 (2016)
Incomplete immune response to coxsackie B viruses associates with early autoimmunity against insulin.
2016 Scientific Article in Clinica Chimica Acta Clin. Chim. Acta 462, 60-64 (2016)
3 screen islet cell autoantibody ELISA: A sensitive and specific ELISA for the combined measurement of autoantibodies to GAD65, TO IA-2 and TO ZnT8.
2016 Letter to the Editor in JAMA: Journal of the American Medical Association JAMA 316, 883-883:883 (2016)
Association of infection in early life and risk of developing type 1 diabetes - reply.
2016 Scientific Article in Diabetes Technology & Therapeutics Diabetes Technol. Ther. 18, 687-693 (2016)
3 screen ELISA for high-throughput detection of beta cell autoantibodies in capillary blood.
2016 Scientific Article in Diabetologia Diabetologia 59, 2172-2180 (2016)
A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children.
2016 Scientific Article in Diabetologia Diabetologia 59, 2193-2202 (2016)
Lactation is associated with altered metabolomic signatures in women with gestational diabetes.
2016 Scientific Article in Diabetes Aktuell Diabetes akt. 14, 186-191 (2016)
Gestationsdiabetes postpartal – Typ-2-Diabetes-Risikoabschätzung und präventive Therapie.
2016 Scientific Article in Current Diabetes Reports Curr. Diab. Rep. 16:75 (2016)
Follicular helper T cells in autoimmunity.
2016 Scientific Article in Atherosclerosis Atherosclerosis 251, 164-169 (2016)
Beyond intima-media-thickness: Analysis of the carotid intima-media-roughness in a paediatric population.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:27887 (2016)
Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY study.
2016 Scientific Article in Diabetes Care Diabetes Care 39, 1535-1542 (2016)
Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY study.
2016 Scientific Article in Diabetes, Stoffwechsel und Herz Diabetes Stoffwechs. Herz 25, 79-83 (2016)
Kinder mit Frühstadium des Typ-1-Diabetes: Drei Fallberichte aus der Fr1da-Studie.
2016 Scientific Article in Diabetologia Diabetologia 59, 1973-1976 (2016)
Tetraspanin 7 autoantibodies in type 1 diabetes.
2016 Scientific Article in BMJ Open BMJ Open 6:e011144 (2016)
Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: Design and initial results of the Fr1da study.
2016 Scientific Article in JAMA: Journal of the American Medical Association JAMA 315, 1899-1901 (2016)
Infections in early life and development of type 1 diabetes.
2016 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 15:72 (2016)
Achievement of treatment goals for secondary prevention of myocardial infarction or stroke in 29,325 patients with type 2 diabetes: A German/Austrian DPV-multicenter analysis.
2016 Scientific Article in Microbiome Microbiome 4:17 (2016)
Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0152476 (2016)
Identification of non-HLA genes associated with celiac disease and country-specific differences in a large, international pediatric cohort.
2016 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 103, 1472-1481 (2016)
Reduction of the n-6:n-3 long-chain PUFA ratio during pregnancy and lactation on offspring body composition: Follow-up results from a randomized controlled trial up to 5 y of age.
2016 Meeting abstract in Diabetic Medicine Diabetic Med. 33, 76-77 (2016)
Is there regulation of the autoimmune response in slow progressors to type 1 diabetes?
2016 Letter to the Editor in Epidemiology Epidemiology 27, E26-E28 (2016)
Response to: Ambient air pollution is not associated with early manifestation of type 1 diabetes.
2016 Scientific Article in Diabetes Diabetes 65, 1988-1995 (2016)
Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The Environmental Determinants of Diabetes in the Young Study.
2016 Review in Molecular Metabolism Mol. Metab. 5, 255-262 (2016)
Primary prevention of beta-cell autoimmunity and type 1 diabetes - the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives.
2016 Scientific Article in Nature Communications Nat. Commun. 7:10991 (2016)
Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice.
2016 Scientific Article in Journal of Diabetes Research J. Diabetes Res. 2016:4208156 (2016)
Longitudinal frequencies of blood leukocyte sub-populations differ between NOD and NOR mice, but do not predict diabetes in NOD mice.
2016 Scientific Article in Journal of Diabetes Research J. Diabetes Res. 2016:2720650 (2016)
Participant experiences in The Environmental Determinants of Diabetes in the Young study: Common reasons for withdrawing.
2016 Scientific Article in Clinical Gastroenterology and Hepatology Clin. Gastroenterol. Hepatol. 14, 403-409 (2016)
Effects of gluten intake on risk of celiac disease: A case-control study on a Swedish birth cohort.
2016 Scientific Article in JAMA Pediatrics JAMA Pediatr. 170, 20-28 (2016)
Association of early exposure of probiotics and islet autoimmunity in the TEDDY study.
2016 Scientific Article in Acta Diabetologica Acta Diabetol. 53, 433-437 (2016)
Development of a simple tool to predict the risk of postpartum diabetes in women with gestational diabetes mellitus.
2016 Scientific Article in Public Health Nutrition Public Health Nutr. 19, 804-813 (2016)
Factors associated with longitudinal food record compliance in a paediatric cohort study.
2016 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 17, 191-198 (2016)
Vascular risk factors in children, adolescents, and young adults with type 1 diabetes complicated by celiac disease: Results from the DPV initiative.
München, Technische Universität, Fakultät für Medizin, Diss., 2015, 152 S.
Factors that influence age of type 1 diabetes onset and beta cell function in children and adults with newly diagnosed type 1 diabetes.
2015 Meeting abstract in Annals of Nutrition and Metabolism Ann. Nutr. Metab. 67, 413 (2015)
Long-chain polyunsaturated fatty acids during pregnancy/lactation and children's body composition: 5-year follow-up data (INFAT-study).
2015 Scientific Article in Epidemiology Epidemiology 26, e31-e32 (2015)
Ambient air pollution and early manifestation of type 1 diabetes.
2015 Scientific Article in Journal of Virology J. Virol. 89, 857-862 (2015)
Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors.
2015 Scientific Article in Journal of Pediatric Psychology J. Pediatr. Psychol., DOI: 10.1093/jpepsy/jsv092 (2015)
Predicting later study withdrawal in participants active in a longitudinal birth cohort study for 1 year: The TEDDY study.
2015 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 102, 1216-1221 (2015)
Gluten consumption during late pregnancy and risk of celiac disease in the offspring: The TEDDY birth cohort.
2015 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 48, 16-19 (2015)
Risk stratification in women with gestational diabetes according to and beyond current WHO criteria.
2015 Scientific Article in Maternal & Child Nutrition Matern. Child Nutr. 11, 803-814 (2015)
Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 1964-1974 (2015)
Staging presymptomatic type 1 diabetes: A scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2015, 131 S.
Wirkung von Vitamin D3 auf die zellvermittelte Immunantwort bei der Pathogenese des Typ-1-Diabetes.
2015 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 65, 622-626 (2015)
Gender-specific effects of treatment with lifestyle, metformin or sulfonylurea on glycemic control and body weight: A German multicenter analysis on 9108 patients.
2015 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 102, 345-352 (2015)
Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: Results from the TEDDY study.
2015 Scientific Article in Diabetologia Diabetologia 58, 2317-2323 (2015)
Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.
2015 Scientific Article in Clinical Immunology Clin. Immunol. 160, 282–285 (2015)
Compromised immune response in infants at risk for type 1 diabetes born by Caesarean Section.
2015 Review in Current Opinion in Endocrinology, Diabetes and Obesity Curr. Opin. Endocrinol. Diabetes Obes. 22, 270-276 (2015)
General population screening for type 1 diabetes: Has its time come?
2015 Scientific Article in Journal of Telemedicine and Telecare J. Telemed. Telecare 21, 400-407 (2015)
Internet health seeking behaviour of parents attending a general paediatric outpatient clinic: A cross-sectional observational study.
2015 Meeting abstract in Journal of Crohn's and Colitis J. Crohns Colitis 9, S177 (2015)
Outcomes of a large cohort of children with IBDU compared to other IBD subtypes and treatment options- a longitudinal report from the Porto pediatric IBD group of ESPGHAN.
2015 Scientific Article in The American Journal of Gastroenterology : AJG Am. J. Gastroenterol. 110, 915-920 (2015)
HLA-DPB1*04:01 protects genetically susceptible children from celiac disease autoimmunity in the TEDDY study.
2015 Scientific Article in Diabetes Diabetes 64, 3247-3252 (2015)
Reactivity to N-terminally truncated GAD65(96-585) identifies GAD autoantibodies that are more closely associated with diabetes progression in relatives of patients with type 1 diabetes.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 989-996 (2015)
Predicting type 1 diabetes using biomarkers.
2015 Scientific Article in Diabetes Diabetes 64, 3239-3246 (2015)
Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes.
2015 Scientific Article in Nature Communications Nat. Commun. 6:7000 (2015)
Widespread seasonal gene expression reveals annual differences in human immunity and physiology.
2015 Scientific Article in JAMA: Journal of the American Medical Association JAMA 313, 1541-1549 (2015)
Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized clinical trial.
2015 Scientific Article in BMC Pediatrics BMC Pediatr. 15:24 (2015)
A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY.
2015 Scientific Article in Pediatrics Pediatrics 135, 239-245 (2015)
Age at gluten introduction and risk of celiac disease.
2015 Scientific Article in Pediatrics Pediatrics 135, 627-634 (2015)
Clinical features of celiac disease: A prospective birth cohort.
2015 Scientific Article in Diabetologia Diabetologia 58, 980-987 (2015)
The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: The TEDDY study.
2015 Scientific Article in Clinical Immunology Clin. Immunol. 157, 216-225 (2015)
Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines.
2015 Scientific Article in Journal of Immunology J. Immunol. 194, 2531-2538 (2015)
High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 808-813 (2015)
Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).
2015 Scientific Article in Diabetes Care Diabetes Care 38, 329-332 (2015)
Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes.
2015 Scientific Article in Diabetes Diabetes 64, 1818-1829 (2015)
Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY study.
2015 Scientific Article in Diabetologia Diabetologia 58, 411-413 (2015)
Progression from single to multiple islet autoantibodies often occurs soon after seroconversion: Implications for early screening.
2015 Scientific Article in Archivum Immunologiae et Therapiae Experimentalis Arch. Immunol. Ther. Exp. 63, 53-63 (2015)
Cyclosporine A regulates pro-inflammatory cytokine production in ulcerative colitis.
2015 Scientific Article in Acta Diabetologica Acta Diabetol. 52, 621-624 (2015)
Early infant feeding and risk of developing islet autoimmunity and type 1 diabetes.
2015 Scientific Article in Public Health Nutrition Public Health Nutr. 18, 50-58 (2015)