IDF

The Institute of Diabetes Research (IDF) is dedicated to studying the natural history of type 1 diabetes, identifying mechanisms and predictive markers of the disease, investigating the pathology of the human pancreas, and implementing novel treatment approaches in clinical trials to prevent type 1 diabetes.

Institute Director Deputy Director Your Contribution

The Institute of Diabetes Research (IDF) is dedicated to studying the natural history of type 1 diabetes, identifying mechanisms and predictive markers of the disease, investigating the pathology of the human pancreas, and implementing novel treatment approaches in clinical trials to prevent type 1 diabetes.

Institute Director Deputy Director Your Contribution

Doctor diagnose pancreas of the patient on the blurred background.

EDENT1FI

EDENT1FI is a global consortium comprised of 28 partners spanning 12 countries. These partners have come together with a shared mission: to identify T1D at its pre-clinical stage in children in the general population. The project is funded through the Horizon Europe program and is set to run over five years.

EDENT1FI website

Press release

European pre-T1D Registry

European pre-T1D Registry is a network of investigators who register children and adults diagnosed with early-stage type 1 diabetes to inform about monitoring, trials, and treatment to delay or prevent disease progression. European pre-T1D Registry is operated by Helmholtz Munich under the umbrella of GPPAD & INNODIA.

pre-T1D Registry website

pre-T1D Registry dashboard

K1DS ARE HEROES

The K1DS ARE HEROES campaign spots type 1 diabetes heroes around the world! The campaign aims to raise awareness for type 1 diabetes, early detection and prevention of type 1 diabetes. The campaign is run by GPPAD together with the Institute of Diabetes Research (IDF) at Helmholtz Munich.

EASD 2026 - Award Anette-Gabriele Ziegler

Three scientists from Helmholtz Munich and the German Center for Diabetes Research (DZD) were honored with prestigious awards at the annual meeting of the European Association for the Study of Diabetes (EASD) from September 28 to October 2, 2026, in…

World Diabetes Awareness: Blue Ribbon, Sugar Cubes, and Globe on Blue Background.

An international team of experts has issued specific recommendations for population-wide screening of children for type 1 diabetes. The consensus paper, published in the journal Diabetologia, sets out when children should be tested and how a…

A daily routine for children with type 1 diabetes: monitoring blood glucose.

Research fully realizes its value where it reaches people – when findings translate into new treatment options from which those affected can benefit. How this can be achieved in practice for type 1 diabetes is demonstrated by the Institute of…

Institut für Diabetesforschung Studienzentrum

For ten years, the Fr1da study, coordinated by Helmholtz Munich, has been investigating whether early stages of type 1 diabetes in children can be detected in routine pediatric care. The latest evaluation shows that the screening program is…

Screenshot pancreas für research area "type 1 diabetes pathology" (Teresa Rodgriguez-Calvo)

Dr. Teresa Rodriguez-Calvo from Helmholtz Munich has been awarded two prestigious grants from Breakthrough T1D, the leading global type 1 diabetes (T1D) research and advocacy organization. The funding will support two innovative projects at the…

As part of the Fr1da study, “Early detection and early treatment of type 1 diabetes”, led by researchers at the Institute of Diabetes Research at Helmholtz Munich, families can have their children aged two to ten tested for an early stage of type 1…

Fehn, A. ; Bonifacio, E. ; Bonnin, E. ; Casteels, K. ; Gündert, M. ; Heigermoser, M. ; Jönsson, I. ; Kordonouri, O. ; Loff, A. ; Lundgren, M. ; Ołtarzewski, M. ; Owen, C. ; Robson, S. ; Roloff, F. ; Szypowska, A. ; Rochtus, A. ; Weiss, A. ; Winkler, C. ; Ziegler, A.-G. ; Haupt, F.

Feasibility of fast turnaround genetic screening for type 1 diabetes risk in newborns—recruiting infants for the global platform for the prevention of autoimmune diabetes primary prevention study supplementation with Bifidobacterium infantis for mitigation of type 1 diabetes autoimmunity.

Mattila, M. ; Mramba, L.K. ; Niinistö, S. ; Erlund, I. ; Liu, X. ; Uusitalo, U. ; Aronsson, C.A. ; Hummel, S. ; Frohnert, B.I. ; Parikh, H.M. ; Rich, S.S. ; Hagopian, W. ; Toppari, J. ; Lernmark, A. ; Ziegler, A.-G. ; Rewers, M. ; Krischer, J.P. ; Hakola, L. ; Norris, J.M. ; Virtanen, S.M.

Dietary vitamin C intake and the risk of islet autoimmunity and type 1 diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY) Study.

Bonifacio, E. ; Winkler, C. ; Ziegler, A.-G.

Screening for Early-Stage Type 1 Diabetes in Children—Reply.

Zapardiel-Gonzalo, J. ; Winkler, C. ; Haupt, F. ; Jolink, M. ; Käßl, A. ; Hatzikotoulas, K. ; Ziegler, A.-G. ; Bonifacio, E.

Polygenic risk scores for islet autoantibody positive early-stage type 1 diabetes pre-screening.

Rosenzwajg, M. ; Hartemann, A. ; Halbron, M. ; Amouyal, C. ; Thivolet, C. ; Rigalleau, V. ; Fontaine, P. ; Mignot, B. ; Reynaud, R. ; Carel, J.C. ; Bismuth, E. ; Storey, C. ; Bourdet, K. ; Sonnet, E. ; Baron, S. ; Nicolino, M. ; Perge, K. ; Chaillous, L. ; Kessler, L. ; Mansilla, M. ; Achenbach, P. ; Ziegler, A.-G. ; Aanstoot, H.J. ; Mouraux, T. ; Casteels, K. ; Donath, M.Y. ; Roep, B.O. ; Lorenzon, R. ; Ribet, C. ; Salem, J.E. ; Pitoiset, F. ; Roux, A. ; Vicaut, E. ; Klatzmann, D.

Efficacy and safety of low-dose IL-2 in people with newly diagnosed type 1 diabetes (DIABIL-2): A double-blind, multicentre, randomised, placebo-controlled, phase 2b trial.

Univ.-Prof. Dr. med. Anette-Gabriele Ziegler

Institute Director, Chair of Diabetes and Gestational Diabetes, Klinikum rechts der Isar and Technical University of Munich, Director of the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD)

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Prof. Dr. med. Peter Achenbach

Deputy Director, Lead Scientist Research Area: Study Center for Childhood Diabetes

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Portrait Sandra Hummel; Querformat, neutraler Hintergrund;

Prof. Dr. oec. troph. Sandra Hummel

Lead Scientist Research Area: Lifestyle, Obesity, and Epigenetic Programming in Type 1 and Gestational Diabetes

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Portrait Christiane Winkler; Querformat;

Dr. rer. biol. hum. Christiane Winkler

Lead Scientist Research Area: Early Diagnosis & Staging of Type 1 Diabetes, and Phenotyping

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Dr. Raffael Ott

Lead Scientist Research Area: Computational Biology and Immune Response Trajectories of Type 1 Diabetes Development

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Dr. rer. nat. Florian Haupt

Lead Scientist Research Area: Digital Networking for Type 1 Diabetes Research

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Porträt Teresa Rodriguez; IDF; Hintergrund: grau

Dr. Teresa Rodriguez-Calvo

Lead Scientist Research Group: Type 1 Diabetes Pathology

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Univ.-Prof. Dr. med. Anette-Gabriele Ziegler

Institute Director, Chair of Diabetes and Gestational Diabetes, Klinikum rechts der Isar and Technical University of Munich, Director of the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD)

+49 89 3187 2896

anettegabriele.zieglerspam prevention@helmholtz-munich.de Website

Heidemannstraße 1, 80939 München

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On This Page

EDENT1FI

European pre-T1D Registry

K1DS ARE HEROES

Triple Recognition for Diabetes Research at Helmholtz Munich

Experts Recommend Systematic Screening of Children for Type 1 Diabetes

From the Lab to the Patient: Four Clinical Trials on Type 1 Diabetes

Early Detection of Type 1 Diabetes in Children Is Broadly Feasible

New Funding Supports Research into Causes and Treatment of Type 1 Diabetes

Fr1da Study Expands Early Diabetes Detection to 12 German Federal States