IDF | Helmholtz Munich

The Institute of Diabetes Research (IDF) is dedicated to studying the natural history of type 1 diabetes, identifying mechanisms and predictive markers of the disease, investigating the pathology of the human pancreas, and implementing novel treatment approaches in clinical trials to prevent type 1 diabetes.

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Cyberattack - recovery of IT systems ongoing

On March 15, 2023, a cyberattack from an external source was detected at Helmholtz Munich. Immediately extensive defensive measures were taken. As a result, some employees have still very limited access to their email and telephone. Maximum efforts are ongoing to restore the IT- and communication systems. We ask for your understanding and patience if we are unable to respond as quickly as usual or if processes are delayed. Thank you very much.

K1DS ARE HEROES

is a heroic campaign to raise awareness of type 1 diabetes and inform parents abour early detection options. Find out how you can be a part of the campaign at hero-k1ds.de

Public Engagement, Diabetes, IDF, February 23, 2023

With this new campaign, scientists want to raise awareness for early detection and prevention of type 1 diabetes in children.

blutabnahme-nahaufnahme-institut-fotoshooting-nozy-andreas pfohl-220727_0062

Awards & Grants, IDF, November 21, 2022

In his testament, a deceased member of the Deutscher Diabetiker Bund (DDB) e. V. stated the will to support diabetes research with 200 000 Euro. The money was now donated to the Institute of Diabetes Research of Helmholtz Munich (IDF) led by…

New Research Findings, IDF, October 17, 2022

Study provides novel insights on dynamics of blood sugar levels and autoimmunity in early childhood

When and why does type 1 diabetes manifest in children? For the first time, researchers conducted a long-term study on infants and young children…

Awards & Grants, HI-MAG, IDF, September 24, 2022

Diabetes research: At this year's congress of the European Association for the Study of Diabetes (EASD), Helmholtz Munich scientists received several awards for pioneering ideas and ways to fight the disease.

Awards & Grants, Diabetes, IDF, August 08, 2022

Prof. Dr. Anette-Gabriele Ziegler, Director of the Helmholtz Munich Institute of Diabetes Research (IDF) receives this year’s EASD–Novo Nordisk Foundation Diabetes Prize for Excellence. The prize is awarded to honor outstanding contributions to the…

New Research Findings, Diabetes, IDF, February 14, 2022

It only takes a blood test to detect the autoimmune disease type 1 diabetes in children at an early stage and, thus, prevent severe metabolic derailments. Helmholtz Munich offers the world's largest population-based screening for type 1 diabetes in…

Woman using glucometer on blue background, top view

New Research Findings, IDR, IDF, November 11, 2021

The 100th anniversary of the discovery of insulin is a milestone in diabetes research and insulin continues to be a lifesaver for many people. At the same time, the International Diabetes Federation predicts a rise in the number of diabetes cases to…

Coronavirus Covid-19 background - 3d rendering

New Research Findings, IDF, April 08, 2021

A study by Helmholtz Zentrum München concludes that during the second Corona wave, three to four times more children in Bavaria, Germany were infected with the Corona virus than reported via PCR tests. In addition, the researchers found that about…

SINT1A Kind mit Baby Andreas Pfohl, NOZY Films GmbH

New Research Findings, IDF, February 15, 2021

Type 1 diabetes is the most common metabolic disease in children and adolescents worldwide. It can be particularly dangerous as often there is no diagnosis until severe and sometimes life-threatening symptoms have already developed. The new ‘SINT1A‘…

New Research Findings, IDF, October 29, 2020

A new study lead by Helmholtz Zentrum München indicates a six-fold higher SARS-CoV-2 exposure rate among children in Bavaria, Germany, than reported cases. This highlights the value of population-based antibody screenings for pandemic monitoring. The…

Antibody, immunoglobulin, Y-shaped protein produced mainly by plasma cells

Transfer, New Research Findings, IDF, May 06, 2020

Large-scale antibody testing against the new coronavirus SARS-CoV-2 could help to obtain reliable data on infection rates. Screening children for early stages of type 1 diabetes in Bavaria, "Fr1da-plus" will now integrate SARS-CoV-2 antibody testing…

Diabetes, IDF, January 28, 2020

Researchers at Helmholtz Munich employed the world's first early detection test for type 1 diabetes in a large-scale population study in Bavaria, Germany, and investigated its effects. For the first time, screening for islet autoantibodies makes it…

Diabetes, IDF, November 14, 2019

Starting November 10th, the Institute for Diabetes Research at Helmholtz Munich is carrying out a dialogue campaign titled “LASST UNS ÜBER 1 REDEN” to mark World Diabetes Day 2019 (14 November). The aim is to raise awareness of type 1 diabetes in the…

Diabetes, IDF, October 15, 2019

The Institute of Diabetes Research of the Helmholtz Munich has now registered 100,000 participants in the Bavarian study "Fr1da" on the early detection of type 1 diabetes. The study will be continued with an additional age group under the name…

Variante: Gold Star Awards Luxury Background

Diabetes, IDF, July 31, 2019

It is a major milestone for one of Europe’s biggest health research cooperations: The international platform GPPAD (“The Global Platform for the Prevention of Autoimmune Diabetes”) has successfully screened 100,000 newborns across Europe for an…

Diabetes, IDF, January 22, 2019

This campaign will have impact in Germany: Since January 22, “Sche1sstyp” – a pun, literally “shit type”– has been emblazoned in large letters across 1500 posters in Munich, Berlin, Hanover and Dresden as well as on more than 560 info screens…

Obesity overweight diabetes fitness abdomen adult background

Diabetes, IDF, July 23, 2018

Children of mothers with type 1 diabetes are at significantly higher risk of being overweight and of exhibiting insulin resistance. This was published by scientists from Helmholtz Munich and the Technical University of Munich in the journal…

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Diabetes, IDF, May 04, 2018

An international research group headed by scientists from Helmholtz Munich has developed a method for calculating the risk for developing type 1 diabetes that is significantly superior to earlier methods. By analyzing up to 41 gene sites, it is…

Diabetes, IDF, February 13, 2018

Scientists at Helmholtz Munich have investigated methylation patterns of risk genes for type 1 diabetes. In the ‘Journal of Autoimmunity’ they report a strong methylation signal in the HLA region, which persists throughout life and leads to…

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2022 Journal of Clinical Investigation 2022 Oct 17;132(20):e162123

Warncke, K., Weiss, A., Achenbach, P., von dem Berge, T., Berner, R., Casteels, K., Groele, L., Hatzikotoulas, K., Hommel, A., Kordonouri, O., Elding Larsson, H., Lundgren, M., Marcus, B. A., Snape, M. D., Szypowska, A., Todd, J. A., Bonifacio, E., Ziegler, A. G., & GPPAD and POInT Study Groups

Elevations in blood glucose before and after the appearance of islet autoantibodies in children.

2020 Journal of the American Medical Association JAMA. 2020;323(4):339-351

Ziegler, A.-G. ; Kick, K. ; Bonifacio, E. ; Haupt, F. ; Hippich, M. ; Dunstheimer, D. ; Lang, M. ; Laub, O. ; ... ; Assfalg, R. ; Jolink, M. ; Winkler, C. ; Achenbach, P.

Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany.

2019 Diabetes Diabetes 2019;68(4):847–857

Hippich, M. ; Beyerlein, A. ; Hagopian, W.A. ; Krischer, J.P. ; Vehik, K. ; Knoop, J. ; Winker, C. ; ... ; Ziegler, A.-G. ; The Teddy Study Group

Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families.

2013 Journal of the American Medical Association JAMA. 2013;309(23):2473-2479

Anette G. Ziegler, MD; Marian Rewers, MD, PhD; Olli Simell, MD, PhD; Tuula Simell, MPH, PhD; Johanna Lempainen, MD, PhD; Andrea Steck, MD; Christiane Winkler, PhD; Jorma Ilonen, MD, PhD; Riitta Veijola, MD, PhD; Mikael Knip, MD, PhD; Ezio Bonifacio, PhD; George S. Eisenbarth, MD, PhD

Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children.

Logo Deutsches Zentrum für Diabetesforschung;

DZD

INNODIA

TrialNet

GPPAD

Fr1da plex

Teddy consortium

nPOD

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Univ.-Prof. Dr. med. Anette-Gabriele Ziegler

Institute Director, Chair of Diabetes and Gestational Diabetes, Klinikum rechts der Isar and Technical University of Munich, Director of the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) View profile

Prof. Dr. med. Peter Achenbach

Deputy Director, Lead Scientist Research Area: Study Center for Childhood Diabetes

Prof. Dr. oec. troph. Sandra Hummel

Lead Scientist Research Area: Lifestyle, Obesity, and Epigenetic Programming in Type 1 and Gestational Diabetes View profile

Dr. rer. biol. hum. Christiane Winkler

Lead Scientist Research Area: Early Diagnosis & Staging of Type 1 Diabetes, and Phenotyping View profile

Dr. Raffael Ott

Lead Scientist Research Area: Computational Biology and Immune Response Trajectories of Type 1 Diabetes Development View profile

Dr. rer. nat. Florian Haupt

Lead Scientist Research Area: Digital Networking for Type 1 Diabetes Research View profile

Dr. Teresa Rodriguez-Calvo

Lead Scientist Junior Research Group: Type 1 Diabetes Pathology View profile

Helmholtz Diabetes Center Institute of Diabetes Research

Research Areas

Early Diagnosis & Staging of Type 1 Diabetes, and Phenotyping

Global Platform for the Prevention of Autoimmune Diabetes (GPPAD)

Study Center for Childhood Diabetes - Studies for Prevention and Immunotherapy of Type 1 Diabetes

Digital Networking for Type 1 Diabetes Research

Lifestyle, Obesity, and Epigenetic Programming in Type 1 and Gestational Diabetes

Computational Biology and Immune Response Trajectories of Type 1 Diabetes Development

Junior Research Group: Type 1 Diabetes Pathology

Institute: Type 1 Diabetes Immunological Tolerance

K1ds are Heroes - An Awareness Campaign on Type 1 Diabetes

K1DS ARE HEROES

K1DS ARE HEROES - Helmholtz Munich and GPPAD present the Type 1 Diabetes Awareness Campaign

200 000 Euro donated for the prevention of Type-1-Diabetes

Type 1 diabetes: New findings on the development of the autoimmune disease in children

Excellent Research Against Diabetes

Anette-Gabriele Ziegler Receives EASD–Novo Nordisk Foundation Diabetes Prize for Excellence 2022

Type 1 Diabetes in Children: Only 22 Euros for an Early Diagnosis Before Symptoms Arise

Perspectives on the Future of Diabetes Research

Children and Corona: Study detects more infections than reported cases during the second wave in Germany

New Clinical Study Aims to Prevent Type 1 Diabetes in Children

More Infections Than Reported: New Study Demonstrates Importance of Large-Scale SARS-CoV-2 Antibody Screenings

Established Study Combines Early Detection of Type 1 Diabetes With Sars-Cov-2 Antibody Testing in Thousands of Children

Type 1 diabetes: Time to consider standard care screenings

“LASST UNS ÜBER 1 REDEN“: New campaign drives dialogue on type 1 diabetes

Study on early detection of type 1 diabetes reaches milestone and continues

100 000 babies screened for increased type 1 diabetes risk in Freder1k Study

Cursing in the name of science: campaign to raise awareness for type 1 diabetes

Children of mothers with type 1 diabetes have a higher body mass index

Improved assessment of the genetic risk of type 1 diabetes

New Methylation Patterns in Type 1 Diabetes Detected

Currently Recruiting

Freder1k study

SINT1A study

Fr1da study

Highlight publications

Networks & Affiliations

DZD

INNODIA

TrialNet

GPPAD

Fr1da plex

Teddy consortium

nPOD

Team

Univ.-Prof. Dr. med. Anette-Gabriele Ziegler

Prof. Dr. med. Peter Achenbach

Prof. Dr. oec. troph. Sandra Hummel

Dr. rer. biol. hum. Christiane Winkler

Dr. Raffael Ott

Dr. rer. nat. Florian Haupt

Dr. Teresa Rodriguez-Calvo

Contact

Univ.-Prof. Dr. med. Anette-Gabriele Ziegler