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Computational Health Center Institute of Neurogenomics

We study the genomic basis of neurological diseases in order to pave the way to a healthier life.

We study the genomic basis of neurological diseases in order to pave the way to a healthier life.

Our Mission

Our overall goal is to identify the genomic basis of neurological diseases in order to improve the diagnosis of our patients and provide tailored personalized treatment. We seek to understand the genomic architecture of complex inherited diseases and to study the underlying molecular mechanisms that burden patients with an increased susceptibility. Understanding predisposition allows us to model how environmental factors coalesce to amplify disease manifestation. This knowledge helps us to formulate precise treatments for our patients, taking into consideration their genetic makeup as well as “multi-omic” information. Ultimately, we want to combat disease by predicting susceptibility at an early stage and then preventing the onset.

Our approach is to combine clinical insight gleaned from our patients with high-throughput “omics” analysis such as array-based genotyping, next generation sequencing, and analysis of the proteome, transcriptome and other omics layers. We then investigate the functional relevance of identified markers using cellular and animal models.

We partner with specialized outpatient clinics at the Klinikum rechts der Isar of the Technische Universität München and specialized hospitals in order to learn the needs of our patients. Moreover, with respect for patients and their family’s cooperative spirit, we can transfer the knowledge we gain directly back into the clinic for prevention, self-observation and treatment. 

Research Groups

Helmholtz Munich | cco Barbara Schormair

Precision Neuromedicine / Winkelmann/Schormair Lab

We strive to achieve comprehensive genetic and multi-omic disease characterization to enable mechanistic understanding as well as improved health outcomes via enhanced prediction, prevention, diagnosis, and personalized treatment.

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Neurogenetic Systems Analysis / Oexle Lab

We address the principles of neural biosystems, their genetic foundations, and their pathological alterations. We use the results of our investigations for improving diagnostics and disease prediction.

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Prokisch Lab

We aim at providing computational solutions for patient diagnosis and treatment.

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Neuronal and Astrocytic Partnerships for Sleep physiology laboratory (NAPS Lab) / Williams Lab

We aim to study how the brain senses sleep and to identify which brain cells are responsible for translating sleep need into actual sleep time.

People at ING

Nikita Konstantinovskiy

Doctorand

Martin Pavlov

Doctorand

Dr.med Christiane Neuhofer

Post Doc

Sabrina Primus

ING Office

Dr. Barbara Schormair

Stellvertretende Leiterin

Dr. Erik Tilch

Post Doc

Prof. Dr. Juliane Winkelmann

Direktorin

Priv.-Doz. Dr. Michael Zech

Senior Scientist

Dr. Chen Zhao

Wissenschaftlicher Mitarbeiter

Dr. Matias Wagner

Post Doc

Volker Kittke

Doktorand

Monika Zimmermann

Technische Assistentin

Prof. Dr. Konrad Oexle

AG Leiter

Prof. Dr. Dr. h. c. Wolfgang H. Oertel

Wissenschaftler

Nathalie Schandra

Neurologin

Dr. Rhiannan Williams

AG Leiterin

Philip Harrer

Doktorand

Chia-Luen Leu

Doktorand

Dr. Nazanin Mirza-Schreiber

Wissenschaftliche Mitarbeitern

Celestine Dutta

Technische Assistentin

Dr. Arcangela Iuso

Post Doc

Enrica Zanuttigh

Doktorandin

Dr. Holger Prokisch

AG Leiter

Dr. Riccardo Berutti

Post Doc

Marieta Borzes

Technische Assistentin

Michael Färberböck

Technischer Assistent

Dmitrii Smirnov

Doktorand

Robert Kopajtich

Wissenschaftlicher Mitarbeiter

Lea Dewi Schlieben

Doktorandin

Ivana Džinović

Doktorandin

Elisabeth Stephan

Technische Assistentin

Martina Kuhnert

Assistentin der AG Leitung

Dr. Eva Winnebeck

Senior Scientist

Vanessa Mandel

Doktorandin

Dr. Theresa Brunet

Post Doc

Dr. Simone Schuffenhauer

Post Doc

Dr. Cătălina Vasilescu

Post Doc

Dr. Masaru Shimura

Post Doc

Aiman Farzeen

Doktorandin

Fatemeh Peymani

Doktorandin

Dr. Margarita Hessel

Wissenschaftliche Mitarbeiterin

Publications

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