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Helmholtz Munich | Petra Nehmeyer

Dr. Rui Wang-Sattler

Group Leader
+49 89 3187 3978Email meBuilding/Room: 3533/209

"We aim to improve personalized healthcare by integrating OMICs data using statistical, bioinformatical and machine learning approaches."


"We aim to improve personalized healthcare by integrating OMICs data using statistical, bioinformatical and machine learning approaches."



Rui works in the field of metabolic diseases (e.g. type 2 diabetes and cardiovascular diseases). She employs statistical, bioinformatical and machine learning approaches to integrate metabolomics, transcriptomics, epigenomics, genomics data, in order to identify candidate biomarkers and drug targets, with the final goal to translate our discoveries into clinical practice.

Academic Journey

Rui studied physics and received her diploma from Heidelberg University. For doctoral and postdoctoral research, she worked on population genetics and immunity in the fight against malaria at the European Molecular Biology Laboratory (EMBL). Since 2007, her research focusses on metabolomics studies at the Helmholtz Munich. Rui aims to improve personalized healthcare by integrating OMICs data using machine learning approaches, and to train the next generation of researchers.


Metabolomics OMICs data integration Machine LearningMetabolic DiseasesPharmaometabolomics   

Professional Background


2022 Group Leader ITG Group Helmholtz Munich, Germany

2011 – 2021

Group Leader AME/EPI Helmholtz Munich Germany

2007 - 2011

Senior Scientist EPI Helmholtz Munich Germany

2000 -2007

Postdoctoral Scientist Kafatos & Steinmetz labs EMBL Heidelberg Germany

1995 - 2000

PhD Kafatos lab EMBL Heidelberg Germany

1990 - 1995

Study of Physics Heidelberg University Germany

Honors and Awards

  • 2010: Paula and Richard von Hertwig Award for Interdisciplinary Cooperation

  • 2018: "Verein der Freunde und Förderer" of the Helmholtz Zentrum München (VdFF). VdFF Prize award for Interdisciplinary Collaboration 2016 – 2017


See all

Tao Xu, Stefan Brandmaier, Ana C Messias, Christian Herder, Harmen H M Draisma, Ayse Demirkan, Zhonghao Yu, Janina S Ried , Toomas Haller, Margit Heier, Monica Campillos, Gisela Fobo, Renee Stark, Christina Holzapfel, Jonathan Adam, Shen Chi, Markus Rotter, Tommaso Panni, Anne S Quante, Ying He, Cornelia Prehn, Werner Roemisch-Margl, Gabi Kastenmüller, Gonneke Willemsen, René Pool, Katarina Kasa, Ko Willems van Dijk, Thomas Hankemeier, Christa Meisinger, Barbara Thorand, Andreas Ruepp, Martin Hrabé de Angelis, Yixue Li, H-Erich Wichmann, Bernd Stratmann, Konstantin Strauch, Andres Metspalu, Christian Gieger, Karsten Suhre, Jerzy Adamski, Thomas Illig, Wolfgang Rathmann, Michael Roden, Annette Peters, Cornelia M van Duijn, Dorret I Boomsma, Thomas Meitinger, Rui Wang-Sattler

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

Rui Wang-Sattler, Zhonghao Yu, Christian Herder, Ana C Messias, Anna Floegel, Ying He, Katharina Heim, Monica Campillos, Christina Holzapfel, Barbara Thorand, Harald Grallert, Tao Xu, Erik Bader, Cornelia Huth, Kirstin Mittelstrass, Angela Döring, Christa Meisinger, Christian Gieger, Cornelia Prehn, Werner Roemisch-Margl, Maren Carstensen, Lu Xie, Hisami Yamanaka-Okumura, Guihong Xing, Uta Ceglarek, Joachim Thiery, Guido Giani, Heiko Lickert, Xu Lin, Yixue Li, Heiner Boeing, Hans-Georg Joost, Martin Hrabé de Angelis, Wolfgang Rathmann, Karsten Suhre, Holger Prokisch, Annette Peters, Thomas Meitinger, Michael Roden, H-Erich Wichmann, Tobias Pischon, Jerzy Adamski, Thomas Illig

Novel biomarkers for pre-diabetes identified by metabolomics