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Wang-Sattler Group

We aim to improve personalized healthcare by integrating OMICs data using statistical, bioinformatical and machine learning approaches.

We aim to improve personalized healthcare by integrating OMICs data using statistical, bioinformatical and machine learning approaches.

Scientific Focus

The Wang-Sattler group is studying metabolic diseases (e.g. type 2 diabetes and cardiovascular diseases). We use statistical, bioinformatical and machine learning approaches to integrate metabolomics, transcriptomics, epigenomics, genomics data, and information from public databases to better understand the pathophysiological mechanisms. This helps us to identify candidate biomarkers and drug targets, with the final goal to translate our discoveries into clinical practice.

The Wang-Sattler Group

Rui Wang-Sattler

Group Leader

3533/209

Makoto Harada

PostDoc

3533/210

Siyu Han

PhD Student

3533/210

Mengya Shi

PhD Student

3533/210

Shixiang Yu

PhD Student

3533/210

Publications

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Tao Xu, Stefan Brandmaier, Ana C Messias, Christian Herder, Harmen H M Draisma, Ayse Demirkan, Zhonghao Yu, Janina S Ried , Toomas Haller, Margit Heier, Monica Campillos, Gisela Fobo, Renee Stark, Christina Holzapfel, Jonathan Adam, Shen Chi, Markus Rotter, Tommaso Panni, Anne S Quante, Ying He, Cornelia Prehn, Werner Roemisch-Margl, Gabi Kastenmüller, Gonneke Willemsen, René Pool, Katarina Kasa, Ko Willems van Dijk, Thomas Hankemeier, Christa Meisinger, Barbara Thorand, Andreas Ruepp, Martin Hrabé de Angelis, Yixue Li, H-Erich Wichmann, Bernd Stratmann, Konstantin Strauch, Andres Metspalu, Christian Gieger, Karsten Suhre, Jerzy Adamski, Thomas Illig, Wolfgang Rathmann, Michael Roden, Annette Peters, Cornelia M van Duijn, Dorret I Boomsma, Thomas Meitinger, Rui Wang-Sattler

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

Rui Wang-Sattler, Zhonghao Yu, Christian Herder, Ana C Messias, Anna Floegel, Ying He, Katharina Heim, Monica Campillos, Christina Holzapfel, Barbara Thorand, Harald Grallert, Tao Xu, Erik Bader, Cornelia Huth, Kirstin Mittelstrass, Angela Döring, Christa Meisinger, Christian Gieger, Cornelia Prehn, Werner Roemisch-Margl, Maren Carstensen, Lu Xie, Hisami Yamanaka-Okumura, Guihong Xing, Uta Ceglarek, Joachim Thiery, Guido Giani, Heiko Lickert, Xu Lin, Yixue Li, Heiner Boeing, Hans-Georg Joost, Martin Hrabé de Angelis, Wolfgang Rathmann, Karsten Suhre, Holger Prokisch, Annette Peters, Thomas Meitinger, Michael Roden, H-Erich Wichmann, Tobias Pischon, Jerzy Adamski, Thomas Illig

Novel biomarkers for pre-diabetes identified by metabolomics