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Plant Genome and Systems Biology

The PGSB plant genomics group focuses on the analysis of plant genomes, using bioinformatic techniques. Our mission is to develop options for a sustainable use of plants and understand how climate change impacts crops, food security and human health.

The PGSB plant genomics group focuses on the analysis of plant genomes, using bioinformatic techniques. Our mission is to develop options for a sustainable use of plants and understand how climate change impacts crops, food security and human health.

Research Topics

Helmholtz Munich
PGSB

Plant Genome Analysis

Analysis of plant genomes: these efforts include structural and functional annotation of genes, transposable elements, transcribed regions and promotor regions as well as comparative genomics and structural genome analyses. The genomic resources generated hereby enable us to identify genes, traits, pathways and crop varieties that shed light into the evolution and domestication of our major crops and can be used for targeted breeding.

Helmholtz Munich | © Manuel Spannagl
PGSB

Cereal Genomics and Human Health

The large and complex genomes of wheat, barley, rye and oat encode unique properties that are critical for human health. This includes beneficial, nutritional properties such as beta-glucans in oats as well as immunopotential properties e.g. related to glutenins in wheat. We investigate the genes, molecular pathways and natural diversity in plant genomes related to these important traits and their impact on human health.

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PGSB

Plant Systems Biology

This research topic deals with the integration and interpretation of large and heterogenous plant genomic data. Multi-scale networks allow e.g. for the integration of transcriptomic and phenotypic data with genome sequence references. The results of this work can accelerate our understanding of molecular pathways and help improve crops and speed up breeding.

Scientists at PGSB

Prof. Dr. Klaus F.X. Mayer

Group Leader

3532/220

Dr. Manuel Spannagl

Deputy Group Leader

3532/219

Dr. Heidrun Gundlach

Postdoc

3532/217

Dr. Georg Haberer

Postdoc

3532 / 218

Dr. Thomas Lux

Postdoc

3532/216

Dr. Nadia Kamal

Postdoc

3532 / 213

Dr. Maxim Messerer

Postdoc

3532/212

Vanda Marosi

PhD Student

3532/215

Sepideh Jafarian

PhD Student

3532/215

Publications

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2022 Scientific Article in The Plant cell

Blankenagel, S. ; Eggels, S. ; Frey, M. ; Grill, E. ; Bauer, E. ; Dawid, C. ; Fernie, A.R. ; Haberer, G. ; Hammerl, R. ; Barbosa Medeiros, D. ; Ouzunova, M. ; Presterl, T. ; Ruß, V. ; Schäufele, R. ; Schlüter, U. ; Tardieu, F. ; Urbany, C. ; Urzinger, S. ; Weber, A.P.M. ; Schön, C.C. ; Avramova, V.

Natural alleles of the abscisic acid catabolism gene ZmAbh4 modulate water use efficiency and carbon isotope discrimination in maize.

2022 Scientific Article in Cell

Hofstatter, P.G. ; Thangavel, G. ; Lux, T. ; Neumann, P. ; Vondrak, T. ; Novak, P. ; Zhang, M. ; Costa, L.T. ; Castellani, M. ; Scott, A. ; Toegelová, H. ; Fuchs, J. ; Mata-Sucre, Y. ; Dias, Y. ; Vanzela, A.L.L. ; Huettel, B. ; Almeida, C.C.S. ; Šimková, H. ; Souza, G. ; Pedrosa-Harand, A. ; Macas, J. ; Mayer, K.F.X. ; Houben, A. ; Marques, A.R.

Repeat-based holocentromeres influence genome architecture and karyotype evolution.

2022 Scientific Article in Nature

Kamal, N. ; Tsardakas Renhuldt, N. ; Bentzer, J. ; Gundlach, H. ; Haberer, G. ; Juhász, A. ; Lux, T. ; Bose, U. ; Tye-Din, J.A. ; Lang, D. ; van Gessel, N. ; Reski, R. ; Fu, Y.B. ; Spégel, P. ; Ceplitis, A. ; Himmelbach, A. ; Waters, A.J. ; Bekele, W.A. ; Colgrave, M.L. ; Hansson, M. ; Stein, N. ; Mayer, K.F.X. ; Jellen, E.N. ; Maughan, P.J. ; Tinker, N.A. ; Mascher, M. ; Olsson, O. ; Spannagl, M. ; Sirijovski, N.

The mosaic oat genome gives insights into a uniquely healthy cereal crop.

Contact us

Prof. Dr. Klaus F.X. Mayer

Group Leader

3532/220