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Helmholtz Munich | © Mara Catani

Dr. Michael Sterr

Group Leader Single-Cell Genomics Unit
+49 89 3187 43152VisitEmail meBuilding/Room: Campus Neuherberg, building 3620, room 034a

Dr. Michael Sterr

Group leader Single-Cell Genomics, Institute of Diabetes and Regeneration Research (IDR)

“By using single-cell genomics, we can increase our understanding of the developmental programs that govern the formation of pancreatic and intestinal endocrine cells to improve diabetes therapy”

Dr. Michael Sterr

Group leader Single-Cell Genomics, Institute of Diabetes and Regeneration Research (IDR)

“By using single-cell genomics, we can increase our understanding of the developmental programs that govern the formation of pancreatic and intestinal endocrine cells to improve diabetes therapy”

Research focus and Academic Career

Michael studied Bioengineering and Biology in Munich.

In 2013 he joined the Lab of Heiko Lickert for his PhD, where he studied the epigenetics of the endocrine cell fate decision in both pancreas and intestine.

During his postdoc time, he focused on single-cell genomics techniques and data analysis to dissect the dynamics of endocrine differentiation.

Since 2021, he leads the Single-Cell Genomics Group at the Institute of Diabetes and Regeneration Research. 

Single-cell based methods are key technologies to uncover the cellular complexity of biological systems, and allow the characterization different cell types and cellular states, as well as the reconstruction developmental trajectories. Leveraging single-cell transcriptomic and epigenomic analyses, Michael aims to provide insight into the molecular mechanisms guiding the endocrine lineage decision and the specification of different endocrine cell types.

Professional Career

2021

Head of the group Single Cell Analysis

Helmholtz Zentrum München, Institute of Diabetes and Regeneration Research, Neuherberg, Germany

2019-2021

Postdoc

Helmholtz Zentrum München, Institute of Diabetes and Regeneration Research, Neuherberg, Germany

2013-2019

PhD Student

Helmholtz Zentrum München, Institute of Diabetes and Regeneration Research, Prof. Dr. Heiko Lickert. Project: “Transcriptional Regulation of Endocrine Cell Formation and Function in Pancreas and Intestine”

Most important publications

PubMed

2022 Clin Cancer Res 1;28(5):1038-1052

Weber P, Künstner A, Hess J, Unger K, Marschner S, Idel C, Ribbat-Idel J, Baumeister P, Gires O, Walz C, Rietzler S, Valeanu L, Herkommer T, Kreutzer L, Klymenko O, Drexler G, Kirchner T, Maihöfer C, Ganswindt U, Walch A, Sterr M, Lickert H, Canis M, Rades D, Perner S, Berriel Diaz M, Herzig S, Lauber K, Wollenberg B, Busch H, Belka C, Zitzelsberger H

Therapy-Related Transcriptional Subtypes in Matched Primary and Recurrent Head and Neck Cancer

2021 Nature 590, 326–331

Ansarullah; Jain, C; Far, FF; Wißmiller, K; Homberg, S; Gräfin von Hahn, F; Raducanu, A; Schirge, S; Sterr, M; Bilekova, S; Siehler, J; Wiener, J; Oppenländer, L; Morshedi, A; Bastidas-Ponce, A; Collden, G; Irmler, M; Beckers, J; Feuchtinger, A; Grzybek, m; Ahlbrecht, C; Feederle, R; Plettenburg, O; Müller, T; Meier, M; Tschöp, M; Coskun, Ü and Lickert, H

Inceptor counteracts insulin signalling in β -cells to control glycaemia