An international research team led by Helmholtz Munich has, for the first time, provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after…

In a new study, researchers at Helmholtz Munich, in collaboration with the Helmholtz Protein Expression and Purification Platform (PEPP), have developed a CRISPR-based technology that activates genes without using DNA or viruses. This method offers a…

Dr. Anthi Krontira from the Institute of Stem Cell Research at Helmholtz Munich has been granted the Klaus Tschira Boost Fund. This funding program, supported by the German Scholars Organization and the Klaus Tschira Stiftung, aims to support early…

A research team led by Dr. Eva Hörmanseder from the Institute of Epigenetics and Stem Cells (IES) has uncovered crucial factors that limit the success of nuclear reprogramming, a process used to change one type of cell into another. While this…

A team of researchers led by Prof. Maria-Elena Torres-Padilla has identified a new factor that plays a crucial role in regulating retrotransposons and genes at the earliest stages of embryonic development. This discovery sheds new light on the moment…

A research team led by Dr. Judith Fischer-Sternjak from Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) München, alongside Prof. Magdalena Götz from Helmholtz Munich, LMU and the Munich Cluster for Systems Neurology (SyNergy), has…

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the genome, researchers at Helmholtz Munich and…

International Top Scientist from Helmholtz Munich Honored with Germany's Most Prestigious Research Award

Do you know how powerful your body is? Dive into this question and more at “Stem Cells, the Genies of the Body,” an interactive exhibition opening at the Deutsches Museum’s Science Communication Lab. Created by scientists from the Helmholtz Munich…

Prof. Magdalena Götz, Director of the Stem Cell Center and the Institute for Stem Cell Research at Helmholtz Munich, LMU Professor and Principal Investigator and Board Member of the SyNergy Cluster of Excellence, has been awarded the Bavarian Order…

The second "Helmholtz Summer School on Chromatin Biology: A Hands-on Expedition", organized by the Helmholtz Munich Institute of Epigenetics and Stem Cells (IES) and the Institute of Functional Epigenetics (IFE) in collaboration with the life science…

Researchers at Helmholtz Munich and Ludwig-Maximilians-University (LMU) have shown how glial cells are reprogrammed into neurons via epigenetic modifications.

Prof. Magdalena Götz about the fascinating research on reprogramming glia cells and cell replacement therapy in the field of brain injuries

Prof. Maria-Elena Torres-Padilla about empowering a team and her enthusiasm for epigenetics.

Prof. Dr. Magdalena Götz has been awarded this year's 150,000 euro science prize by the Hector Foundation. The jury is thus recognizing the neurobiologist's outstanding research achievements.

The Dynamic Journey of DNA Replication Timing and Its Impact on Cellular Plasticity 

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another…

Researchers from Helmholtz Munich and the LMU have discovered that, in the case of brain injuries, specific cells in the brain become active in disease situations, exhibiting properties of neural stem cells. The authors further discovered that a…

Sporadic Parkinson's Disease (sPD) is a progressive neurodegenerative disorder influenced by both genetic and environmental factors. While mitochondrial dysfunction contributes to this condition, its role across disease progression remains unclear.…

The ability to reprogram cells holds great promises for regenerative medicine. Cells from the embryo at the beginning of life divide and produce all cell types in the body. What can embryos teach us so that we can generate cells ‘à la carte’ to cure…

Internationally renowned neurobiologist Magdalena Götz is pursuing important leads in her quest to elucidate the causes of neurological diseases. Together with her team at Helmholtz Munich and Ludwig-Maximilians-Universität München, she has gained…

Replacing sick or damaged cells with healthy cells: this is a major goal of regenerative medicine. One of the most promising approaches is cellular reprogramming, whereby one cell type in our body converts to another cell type. Research carried out…

After a rigorous peer review process, the board of trustees of Academia Europeae, the pan-European academy of science, humanities and letters, has elected the Stem Cell expert Maria-Elena Torres-Padilla as well as the Epigenetics expert Robert…

The gut plays a central role in the regulation of the body’s metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide. Targeting…

Wanted: Established, leading principal investigator with a track-record of significant research achievements in the last 10 years. Found: At Helmholtz Zentrum München. Magdalena Götz and Marcus Conrad both receive an ERC Advanced Grant for their…

In mammalian adult brains, neural stem cells are only present in few specific parts, so called niches. Only these niches are capable of generating new neurons. For the first time, researchers defined the proteome of these niches, the entire set of…