Institute of Molecular Toxicology and Pharmacology

We aim at understanding the molecular machines by which our organism responds to bioactive chemicals and how this translates into benefit or harm to us. A key ambition is to generate the knowledge for the development of innovative, efficient and safe drugs.

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About our Research

Our research targets the interface between biomedicine and chemistry from complementary perspectives. Specific projects may start from:

elicited by a small chemical in mice or man

pathways

for novel chemical matter that could address a promising pharmacologic target

screens to unravel the mechanism behind a physiological response to a chemical challenge

Göttlicher Group

Our research aims at identifying novel targets for small molecules that could modulate intermediary metabolism in order to control body weight or pathologies associated with metabolic disorders such as metabolic syndrome, steatosis hepatis or diabetes.

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Zischka Group

We focus on Mitochondrial Damage upon diverse aspects of cell-toxic conditions in human disease, e.g. metabolic diseases, neurodegeneration, cancer, organ failure.

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Medical concept of cancer. 3d illustration of T cells or cancer cells.

Transfer, New Research Findings, TOXI, April 27, 2021

A small molecule has entered a novel clinical trial for cancer immunotherapy. The molecule inhibits an enzyme called MALT1 that plays a critical role in suppressing immune reactions against tumor cells. Preclinical studies showed that blocking MALT1…

Prof. Martin Göttlicher

Director of the Institute for Molecular Toxicology and Pharmacology / Group Leader Small Molecule Modulators of Intermediary Metabolism View profile

Prof. Dr. rer. nat. Hans Zischka

Group Leader Oxidative Cell Death

Dr. Banu Akdogan

Postdoc Zischka Lab

Carola Eberhagen

Technical Assistant Zischka Lab

Tamara Rieder

Technical Assistant Zischka Lab

Dr. Judith Nagel

Postdoc Zischka Lab

Adriana Filipa da Silva Fontes

Doctoral Researcher Zischka Lab

Quirin Reinold

Technical Assistant Zischka Lab

Judith Sailer

Doctoral Researcher Zischka Lab

Dr. Sabine Schmitt

Postdoc Zischka Lab

Yaschar Kabiri

Doctoral Researcher Zischka Lab

A lot of people figures and comment clouds above their heads.

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Technicians

Molecular Targets and Therapeutics Center Institute of Molecular Toxicology and Pharmacology

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About our Research

Our research targets the interface between biomedicine and chemistry from complementary perspectives. Specific projects may start from:

Research Groups

Small Molecule Modulators of Intermediary Metabolism

Mitochondrial Toxicology

First-in-class Cancer Immunotherapy Drug in Clinical Trial