Prof. Dr. Horst Zitzelsberger
Head Research Unit Radiation Cytogenetics“My vision is a comprehensive understanding of molecular landscapes of human tumors to support precision cancer treatment and to improve clinical outcomes.”
“My vision is a comprehensive understanding of molecular landscapes of human tumors to support precision cancer treatment and to improve clinical outcomes.”
Academic Career and Research Areas
Horst Zitzelsberger received his diploma in human genetics and earned his doctorate in biology.
His scientific career started at the LMU at the Radiobiological Institute as scientific assistant in 1995. A major focus were molecular mechanisms and markers of radiation-induced carcinogenesis. 2001 he took over the leadership of the research group Cytogenetics at the Helmholtz Zentrum München. At the same time he habilitated at the Medical Faculty of the LMU Munich in radiobiology and was appointed as Associated Professor in 2008. In parallel, he became acting director of the Institute of Molecular Radiobiology and expanded his research focus to include translational radiation oncology mainly in the field of head and neck cancer. Until now he is head of the Research Unit Radiation Cytogenetics and implemented together with Kristian Unger multi-omics approaches and translational bioinformatics in the research field. A joint clinical cooperation group with the Department of Radiation Oncology at the LMU (director: Claus Belka) strengthened the focus on clinical cohorts and personalized cancer treatment strategies.
Fields, skills and expertises
Molecular CytogeneticsMulti-Omics studiesTranslational Radiation OncologyPrognostic markersTherapeutic stratification and targets
Recent Publications
Read more2022 Editorial in Radiation and Environmental Biophysics
Obituary: Prof. Dr. Albrecht M. Kellerer (1935-2022).
2022 Scientific Article in Molecular Cancer
A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer.
2022 Scientific Article in European Journal of Cancer
DeepClassPathway: Molecular pathway aware classification using explainable deep learning.
2022 Scientific Article in Cancers
Integration of p16/HPV DNA status with a 24-miRNA-defined molecular phenotype improves clinically relevant stratification of head and neck cancer patients.
2022 Scientific Article in Laboratory Investigation
Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.
2022 Scientific Article in Clinical and translational radiation oncology
Biopsy-derived oral keratinocytes – A model to potentially test for oral mucosa radiation sensitivity.
2022 Scientific Article in Clinical Cancer Research
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.
2021 Scientific Article in Cell Death & Disease