Prof. Dr. Vigo Heissmeyer
Head of Institute of Molecular Immunregulation (AMIR)"Deciphering the molecular mechanisms that control T cell-driven immune responses will create critical knowledge for future therapies against autoimmune diseases or immune cell therapies against cancer."
"Deciphering the molecular mechanisms that control T cell-driven immune responses will create critical knowledge for future therapies against autoimmune diseases or immune cell therapies against cancer."
His academic career started with a PhD in signal transduction at the MDC in Berlin and a Postdoctoral Fellowship at Harvard Medical School in Boston, USA, where he studied transcriptional programs and signal transduction in T helper cells. Returning to Germany and building his own Young Investigator Group at Helmholtz Munich a new focus on post-transcriptional gene regulation by RNA-binding proteins and mRNA modifications was established.
His work aims to understand the post-transcriptional gene regulation underlying T cell fate decisions including development, activation, differentiation and formation of effector or memory cells. These programs protect us from invading pathogens and tumor cells but, once dysregulated, can also cause autoimmunity or inflammation.
Mouse models molecular and cellular immunology,biochemistry in primary T cells
Head of Research Unit (Molecular Immune Regulation, Helmholtz Munich) and Professor at the Institute for Immunology (Ludwig-Maximilians-Universität München)
Tenured Group leader at the Institute of Molecular Immunology (Helmholtz Munich)
Young Investigator at Helmholtz Munich
Postdoctoral Fellow, Harvard Medical School, Boston, USA
Honors and Awards
ERC starting grant
Publications by Vigo Heissmeyer
Read more2022 Review in International Immunology
Roquin-dependent gene regulation in immune-mediated diseases and future therapies.
2022 Scientific Article in Nature Immunology
The function of Wtap in N6-adenosine methylation of mRNAs controls T cell receptor signaling and survival of T cells.
2022 Scientific Article in Immunology Letters
Post-transcriptional control of T-cell development in the thymus.
2022 Review in Frontiers in Immunology
Cooperation of RNA-binding proteins - a focus on roquin function in T cells.
2022 Scientific Article in Nature Communications