Environmental Health Center Asthma and Allergy Prevention
Asthma is an inflammatory disease of the airways of the lung. It is not one disease but a syndrome consisting of many so far not well characterized and delineated genetic and environmental determinants. The focus of our work is to develop novel strategies of asthma and allergy prevention and to characterize in depth asthma phenotypes.
Asthma is an inflammatory disease of the airways of the lung. It is not one disease but a syndrome consisting of many so far not well characterized and delineated genetic and environmental determinants. The focus of our work is to develop novel strategies of asthma and allergy prevention and to characterize in depth asthma phenotypes.
Selected Publications
2021 Am J Respir Crit Care Med DOI: 10.1164/rccm.202106-1458OC (2022)
2020 Acta Med Acad doi: 10.5644/ama2006-124.293
2017 Allergy DOI: 10.1111/all.13002
Environmental and mucosal microbiota and their role in childhood asthma
2015 Science doi: 10.1126/science.aac6623
Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells
2013 J Allergy Clin Immunol. DOI:https://doi.org/10.1016/j.jaci.2012.11.048
2012 J Allergy Clin Immunol doi: 10.1016/j.jaci.2012.03.013
Protection from childhood asthma and allergy in Alpine farm environments
2012 J Allergy Clin Immunol. DOI:https://doi.org/10.1016/j.jaci.2012.04.049
Farming environments and childhood atopy, wheeze, lung function, and exhaled nitric oxide
2011 N Engl J Med. 2011 DOI: 10.1056/NEJMoa1007302
Exposure to environmental microorganisms and childhood asthma
2010 Nat Rev Immunol doi: 10.1038/nri2871
2002 N Engl J Med DOI: 10.1056/NEJMoa020057
Environmental exposure to endotoxin and its relation to asthma in school-age children