December 27, 2022 How our genes are read at the beginning of lifeResearchers from the Institute for Epigenetics and Stem Cells at Helmholtz Munich studied RNA Polymerase II (Pol II) in early mouse embryos and shed light on transcriptional elongation during zygotic genome activation (ZGA), a key process of…read more
IES, IFE, December 19, 2022 The use of embryo models to study development - a perspectiveIn the perspective article "In preprints: improving and interrogating embryo models", Antonio Scialdone from the Institute for Epigenetics and Stem Cells, the Institute of Functional Epigenetics, and the Institute of Computational Biology at…read more
November 09, 2022 The fourth Epigenetics Retreat was a great successThe fourth epigenetics@HelmholtzMunich retreat took place on November 7th – 8th 2022 close to Lake Ammersee in Bavaria.read more
Stem Cells, IES, August 30, 2022 From idea to implementation – Anna Dumitriu ran a workshop about her artwork “The Cellular Reprogramming Necklace”During her stay in August 2022, Anna Dumitriu ran a workshop with researchers at the Institute for Epigenetics and Stem Cells to share her thoughts and experiences of the creative process underlying her artwork “The Cellular Reprogramming Necklace”. read more
Stem Cells, IES, August 09, 2022 What stands behind the message sent by histone PTMs?Over the last 60 years, research has shed light on histone PTMs and their role in all DNA-templated processes. In the last decade, novel methodologies, such as genome-wide sequencing approaches, have paved the way toward understanding how their…read more
Stem Cells, IES, April 08, 2022 Communication is the key, also between cells.Just as we use Google Maps, cells rely on gradient sensing of signal molecules to reach their destination. However, in their case, the destination is the source of the attractant and not the restaurant of choice. Using mathematical models,…read more
Stem Cells, IES, April 02, 2022 Helmholtz Munich is part of the new Innovative Training Network “RepliFate”The EU funds a new Innovative Training Network (ITN) in the field of DNA replication, cell fate, and cancer with Helmholtz Munich as a beneficiary. The ITN will investigate the role of DNA replication as a determinant of cell fate and cancer.read more
Stem Cells, IES, March 22, 2022 Always follow your nose – On the trail of the anatomical logic of smellThe sense of smell is essential for almost all animals. It helps find food, detect dangers, and distinguish between friends and enemies. As the saying goes: You really get up my nose. Research carried out at Helmholtz Munich has shown that…read more
Stem Cells, IES, March 18, 2022 EpIC - EpiGene3Sys meets INC_Spain to ChromDesign the GenomeFrom October 17th to 20th October 2022, the conference "EpIC - EpiGene3Sys meets INC_Spain to ChromDesign the Genome" will take place in Granada, Spain. The registration will open soon.read more
Stem Cells, IES, March 07, 2022 Changing the speed of DNA replication - a new way to improve the cellular reprogramming efficiencyReversing injury or disease is a major objective in research towards regenerative medicine. Replacing sick or damaged cells with healthy cells in order to repair damaged tissue is one of the most impactful strategies towards that goal. For that, a…read more
Stem Cells, IES, February 02, 2022 Summer School on Chromatin Biology: A hands-on expeditionWe are delighted to announce the launch of the "1st Helmholtz Summer School on Chromatin Biology: A hands-on expedition", which will take place at the Neuherberg Campus of Helmholtz Munich, from August 15-26, 2022.read more
Stem Cells, IES, January 03, 2022 Eva Hörmanseder receives DFG grant to investigate cell-fate changes during reprogrammingThe possibility to generate any cell type from a differentiated, somatic cell can advance cell-replacement therapies and holds great promises to regenerative medicine. Therefore, understanding the molecular mechanisms underlying cell-fate changes…read more
Stem Cells, IES, November 18, 2021 A milestone for developmental biology - Scientists publish the first single-transcriptome of a human gastrulation embryoFor the first time, scientists based at Helmholtz Zentrum München and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). Their findings will drive future studies to…read more
Stem Cells, IES, July 22, 2021 The prestigious Academia Europeae has elected our Institute Director as memberAfter a rigorous peer-review process, the board of trustees of Academia Europeae, the pan-European academy of science, humanities, and letters, has elected our Stem Cell expert Prof. Maria-Elena Torres-Padilla. This is a recognition of her standing…read more
Stem Cells, IES, July 21, 2021 Mitochondrial defects characterize 'loser' cells in cell competitionThe work of the Scialdone Lab at the Helmholtz Zentrum München and the Rodriguez at the Imperial College elucidates that differences in mitochondrial activity are key determinants for cellular fitness in various contexts, where endogenous cell…read more