Stem Cell Center
Epigenetics and Stem Cells
At the Institute of Epigenetics and Stem Cells (IES), we aim to unlock a cell's full potential by understanding how a single cell can give rise to all the cells in our body at the beginning of life.
At the Institute of Epigenetics and Stem Cells (IES), we aim to unlock a cell's full potential by understanding how a single cell can give rise to all the cells in our body at the beginning of life.
IES Members
Director of the Stem Cell Center, Director of the Institute for Epigenetics and Stem Cells, Group Leader, Director of the Stem Cell Center (rotating)
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Deputy Head of Institute for Epigenetics and Stem Cells
Head of Microscopy Core
Senior Computational Biologist
Postdoc
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Doctoral Researcher, IES/HPC
Doctoral Researcher
Doctoral Researcher
Doctoral Researcher
Doctoral Researcher
Doctoral Researcher, Torres-Padilla lab
Doctoral Researcher
Research Assistant – Bioinformatics
Lab Manager
Lab Manager
Intern
Administrative Assistant
Our Institute in Numbers
Latest Publications
Uruci, S. ; Boer, D.E.C. ; Chrystal, P. ; Lalonde, M. ; Panagopoulos, A. ; Yakoub, G. ; Kirdök, I. ; Lint, K.d. ; Woude, M.v.d. ; Wendel, T.J. ; Brussee, S. ; Wondergem, A.P. ; Overbeek, N.v. ; Schotman, N. ; Lingeman, J. ; Ljungman, M. ; Vidal, M. ; Attikum, H.v. ; Vertegaal, A.C.O. ; Noordermeer, S.M. ; Wolthuis, R.M.F. ; Altmeyer, M. ; Hamperl, S. ; Tropepe, V. ; Berg, J.v.d. ; Heuvel, D.v.d. ; Luijsterburg, M.S.
CFAP20 salvages arrested RNAPII from the path of co-directional replisomes.Nitsch, S. ; Coraor, A.E. ; Schauer, T. ; Wu, Y. ; Sun, J. ; Möritz, N. ; Funke, J.J. ; Nagpal, H. ; Chua, G.N.L. ; Battistini, F. ; Lauberth, S.M. ; Richard, E.M. ; Orozco, M. ; Liu, S. ; Desviat, L.R. ; Fierz, B. ; Dietz, H. ; Roeder, R.G. ; de Pablo, J.J. ; Schneider, R.
H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations.Oak, M.S. ; Stock, M. ; Janeva, A. ; Mezes, M. ; Hynes-Allen, A.M. ; Straub, T. ; Forné, I. ; Ettinger, A. ; Hamperl, S. ; Imhof, A. ; van den Ameele, J. ; Scialdone, A. ; Hörmanseder, E.
Pre-marking chromatin with H3K4 methylation is required for accurate zygotic genome activation and development.Ummethum, H. ; Murriello, A.C. ; Werner, M. ; Márquez-Gómez, E. ; König, A.-C. ; Kruse, E. ; Lalonde, M. ; Trauner, M. ; Chanou, A. ; Weiß, M. ; Lee, C.S.K. ; Ettinger, A. ; Erhard, F. ; Hauck, S.M. ; Hamperl, S.
The CGG triplet repeat binding protein 1 counteracts R-loop induced transcription-replication stress.Wagner, C.B. ; Longaretti, M. ; Sergi, S.G. ; Singh, N. ; Tsirkas, I. ; Bento, F. ; Wong, R.P. ; Wilkens, M. ; Hamperl, S. ; Butter, F. ; Aharoni, A. ; Ulrich, H.D. ; Luke, B.
Rad53 regulates RNase H1, which promotes DNA replication through sites of transcription-replication conflict.Apostolou, Z. ; Venkatasubramani, A.V. ; Kopp, L.C. ; Kars, G. ; Scacchetti, A. ; Campos-Sparr, A. ; Schauer, T. ; Imhof, A. ; Becker, P.B.
The Tip60 acetylome is a hallmark of the proliferative state in Drosophila.Ewe, C.K. ; Farnworth, M.S. ; Miller, A. ; Navajas Acedo, J. ; Oomen, M.E. ; Paci, G. ; Widen, S.A. ; Yamada, T.
Pathway to Independence: A forecast for the future of developmental biology.Stock, M.
Incorporation of prior knowledge to improve gene regulatory network inference from single-cell transcriptomics data.Iturbide Martinez De Albeniz, A. ; Ruiz Tejada Segura, M.L. ; Noll, C. ; Schorpp, K.K. ; Rothenaigner, I. ; Ruiz-Morales, E.R. ; Lubatti, G. ; Agami, A. ; Hadian, K. ; Scialdone, A. ; Torres-Padilla, M.E.
Addendum: Retinoic acid signaling is critical during the totipotency window in early mammalian development.Fukagawa, T. ; Torres-Padilla, M.E.
Exploring the cell nucleus: From chromosome structure to single-cell omics.Hains, A.E. ; Marques, J.G. ; Chetal, K. ; Nakatani, T. ; Ettinger, A. ; Biagi, C.A.O.d. ; Gonzalez‐Sandoval, A. ; Pillai, R. ; Gatto, A. ; Torres-Padilla, M.E. ; Sadreyev, R.I. ; Filbin, M.G. ; Rechem, C.V.
Abstract SY23-01: Diffuse midline gliomas: From cell cycle to therapeutic opportunities.Nakatani, T.
Dynamics of replication timing during mammalian development.Zikmund, T. ; Fiorentino, J. ; Penfold, C. ; Stock, M. ; Shpudeiko, P. ; Agarwal, G. ; Langfeld, L. ; Petrova, K. ; Peshkin, L. ; Hamperl, S. ; Scialdone, A. ; Hörmanseder, E.
Differentiation success of reprogrammed cells is heterogeneous in vivo and modulated by somatic cell identity memory.
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