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Stem Cell Center Epigenetics and Stem Cells

At the Institute of Epigenetics and Stem Cells (IES),  we aim to unlock a cell's full potential by understanding how a single cell can give rise to all the cells in our body at the beginning of life.

At the Institute of Epigenetics and Stem Cells (IES),  we aim to unlock a cell's full potential by understanding how a single cell can give rise to all the cells in our body at the beginning of life.

Research Groups

GFP-labelled early mouse embryos
Helmholtz Munich | Maria-Elena Torres-Padilla
Torres-Padilla Lab

Epigenetics and cell-fate in early mammalian development

We combine high-resolution microscopy with single-cell genomics to study the epigenetic principles underlying cellular reprogramming in the mouse embryo.

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Transcription-Replication Conflicts under different temperatures
Helmholtz Munich | Anna Dumitriu
Hamperl Lab

Chromosome dynamics and genome stability

We study how DNA replication and transcription can occur simultaneously without major accidents that cause DNA damage and genome instability.

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Transgenic Xenopus Laevis Tadpole
Helmholtz Munich | Eva Hörmanseder
Hörmanseder Lab

Maintaining and Reprogramming Cell Fates

We combine somatic cell nuclear transfer to Xenopus eggs with innovative multi-omics to study how a cell can remember its identity in order to erase its memory.

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Cellular Decision Making
Scialdone et al., Nature, 2016 | John C. Marioni & Berthold Göttgens
Scialdone Lab

Physics and Data-Based Modeling of Cellular Identity Changes

We aim to understand the molecular bases of cell identity changes by combining single-cell and spatial omics data analysis with physical modeling.

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Nicolas Battich
Battich Lab

Quantitative Cell Biology

We are interested in the strategies that cells use to control gene expression levels and variability during differentiation.

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IES members

Portrait Jonathan Adam Burton

Dr. Jonathan Adam Burton

Deputy Head of Institute for Epigenetics and Stem Cells
Portrait Andreas Ettinger

Dr. Andreas Ettinger

Head of Microscopy Core
Portrait Antoine Canat

Dr. Antoine Canat

Postdoc
Portrait Marlies Oomen

Dr. Marlies Oomen

Postdoc
Portrait Maxime Lalonde

Dr. Maxime Lalonde

Postdoc
Clare_ShukKwan.png

Dr. Clare Shuk Kwan Lee

Postdoc
Portrait of Martin Miranda

Dr. Martin Miranda

Postdoc
Portrait Federico Pecori

Dr. Federico Pecori

Postdoc
Portrait Tsunetoshi Nakatani

Dr. Tsunetoshi Nakatani

Postdoc
Ioannis Tsirkas Portrait

Dr. Ioannis Tsirkas

Postdoc
JiezhenMo_selfportrait_personnel

Dr. Jiezhen Mo

Postdoc
Tamas Schauer

Dr. Tamas Schauer

Senior Computational Biologist
Portrait Meghana Oak

Meghana Oak

Doctoral Researcher
Portrait Ana Janeva

Ana Janeva

Doctoral Researcher
Portrait Marcel Werner

Marcel Werner

Doctoral Researcher

Gofur Mohammad Wasiful

Doctoral Researcher
Portrait Gabriele Lubatti

Gabriele Lubatti

Doctoral Researcher

Marco Stock

Doctoral Researcher
Portrait Mrinmoy Pal

Mrinmoy Pal

Doctoral Researcher
Veronica Finazzi self-portrait (personnel)

Veronica Finazzi

Doctoral Researcher
Yicong Chen

Yicong Chen

Doctoral Researcher

Farid Ahadli

Doctoral Researcher
Atiqa Sajid photo

Atiqa Sajid

Doctoral Researcher
Portrait Clara Hermant

Clara Hermant

Doctoral Researcher
Porträt Iliya Nadelson

Iliya Nadelson

Doctoral Researcher

David von Bonin

Doctoral Researcher
Portrait Yung-Li Chen

Yung-Li Chen

Doctoral Researcher
Portrait_selfie_Elizabeth_Gomez

Elizabeth Marquez Gomez

Research Assistant – Bioinformatics

Matthias Mezes

Research assistant

Matteo Zambon

Project Assistant

Margarita Cespedes Barroso

Lab Manager
Xanthoula Karypidou self portrait

Xanthoula Karypidou

Lab Manager

Andres Felipe Gonzalez Suarez

Lab Manager
Portrait Thomas Gerling

Thomas Gerling

Administrative Assistant

Latest Publications

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2023 Scientific Article in Blood

Bamezai, S. ; Pulikkottil, A.J. ; Yadav, T. ; Vegi, N.M. ; Mueller, J. ; Mark, J. ; Mandal, T. ; Feder, K. ; Ihme, S. ; Song, C. ; Rosler, R. ; Wiese, S. ; Hoell, J.I. ; Kloetgen, A. ; Karsan, A. ; Kumari, A. ; Wojenski, L. ; Sinha, A.U. ; González-Menéndez, I. ; Quintanilla-Martinez, L. ; Donato, E. ; Trumpp, A. ; Kruse, E. ; Hamperl, S. ; Zou, L. ; Rawat, V.P.S. ; Buske, C.

A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML.

2023 Review in Nature Protocols

Collins, A. ; Møller, P. ; Gajski, G. ; Vodenková, S. ; Abdulwahed, A. ; Anderson, D. ; Bankoglu, E.E. ; Bonassi, S. ; Boutet-Robinet, E. ; Brunborg, G. ; Chao, C. ; Cooke, M.S. ; Costa, C. ; Costa, S. ; Dhawan, A. ; de Lapuente, J. ; Bo', C.D. ; Dubus, J. ; Dusinska, M. ; Duthie, S.J. ; Yamani, N.E. ; Engelward, B. ; Gaivão, I. ; Giovannelli, L. ; Godschalk, R. ; Guilherme, S. ; Gutzkow, K.B. ; Habas, K. ; Hernandez, A. ; Herrero, O. ; Isidori, M. ; Jha, A.N. ; Knasmüller, S. ; Kooter, I.M. ; Koppen, G. ; Kruszewski, M. ; Ladeira, C. ; Laffon, B. ; Larramendy, M. ; Hégarat, L.L. ; Lewies, A. ; Lewinska, A. ; Liwszyc, G.E. ; de Cerain, A.L. ; Manjanatha, M. ; Marcos, R. ; Milić, M. ; de Andrade, V.M. ; Moretti, M. ; Muruzabal, D. ; Novak, M. ; Oliveira, R. ; Olsen, A.K. ; Owiti, N. ; Pacheco, M. ; Pandey, A.K. ; Pfuhler, S. ; Pourrut, B. ; Reisinger, K. ; Rojas, E. ; Rundén-Pran, E. ; Sanz-Serrano, J. ; Shaposhnikov, S. ; Sipinen, V. ; Smeets, K. ; Stopper, H. ; Teixeira, J.P. ; Valdiglesias, V. ; Valverde, M. ; van Acker, F. ; van Schooten, F.J. ; Vasquez, M. ; Wentzel, J.F. ; Wnuk, M. ; Wouters, A. ; Žegura, B. ; Zikmund, T. ; Langie, S.A.S. ; Azqueta, A.

Measuring DNA modifications with the comet assay: A compendium of protocols.

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Contact

Portrait Thomas Gerling

Thomas Gerling

Administrative Assistant

Contact

Laura Grodtmann_selfportrairt

Laura Grodtmann

Administrative Assistant

Building 90, Room 105