When Metabolism Meets Chromatin: Histone Acylations Tune Gene Expression
Metabolic dysfunction is a hallmark of numerous diseases, including diabetes and other metabolic disorders. But how do changes in our metabolism affect our cells and the way they function? How do they influence our genes?
GRC “Histone and DNA modifications” 2025 organised by Robert Schneider
The 2025 Gordon Research Conference (GRC) "Histone and DNA modifications" conference was organized by Robert Schneider from the Institute for Functional Epigenetics (IFE) at Helmholtz Munich
Robert Schneider will chair the Gordon Research Conference
Dr. Robert Schneider will co-chair the Histone and DNA Modifications Gordon Research Conference, and Dr. Anne-Sophie Pepin the associated Gordon Research Seminar.
This multidisciplinary workshop will bring together 15 OUTSTANDING SPEAKERS with the objective of tackling the various dimensions of epigenetic mechanisms in resilience and adaptation, by providing a platform for researchers to exchange knowledge,…
Gordon Research Conference: Chromatin Modifications in Health and Disease
The Gordon Research Conference "Chromatin Modifications in Health and Disease", co-organised by Robert Schneider, will take place from June 11-16,2023, at Bryant University in Rhode Island. The deadline for abstract submission is on May 14, 2023.
The use of embryo models to study development - a perspective
In the perspective article "In preprints: improving and interrogating embryo models", Antonio Scialdone from the Institute for Epigenetics and Stem Cells, the Institute of Functional Epigenetics, and the Institute of Computational Biology at…
Altered expression response upon repeated gene repression
Cells must continuously adjust to their environments and cope with changing temperatures, stress conditions, or resources. Particularly, if conditions change repeatedly, it might make sense for cells to adjust more effectively. A collaborative…
Cell-ACDC – For those about to analyze microscopy images
Even though deep learning has led to improvements, the downstream analysis of live-cell microscopy images remains a bottleneck. Recently, researchers from the Institute of Functional Epigenetics published their open-source and user-friendly software…
A beginner’s guide to catching the readers – Till Bartke publishes protocols to identify modification-specific nucleosome interactors
As part of the book series ‘Methods in Molecular Biology’, Springer Nature has released the methods and protocols collection ‘Histone Methyltransferases’. The chapter contributed by Till Bartke and colleagues from the Institute of Functional…
Decoding epigenetic modifications – DFG funds CRC 1309 with R. Schneider as project leader
As part of the collaborative research center (CRC) ‘Chemical Biology of Epigenetic Modifications’ (SFB 1309), Robert Schneider, Director of the Institute of Functional Epigenetics’ at Helmholtz Munich, receives funding from the German Research…
FASEB Biological Methylation Conference: bringing basic biochemical findings to therapy organized by R. Schneider
Experts from academia and the pharmaceutical industry came together at “The Biological Methylation Conference: Fundamental Mechanism in Human Health and Disease” in Catania to share new exciting results about protein and RNA methylations as well as…
What stands behind the message sent by histone PTMs?
Over the last 60 years, research has shed light on histone PTMs and their role in all DNA-templated processes. In the last decade, novel methodologies, such as genome-wide sequencing approaches, have paved the way toward understanding how their…
Just as we use Google Maps, cells rely on gradient sensing of signal molecules to reach their destination. However, in their case, the destination is the source of the attractant and not the restaurant of choice. Using mathematical models,…
Always follow your nose – On the trail of the anatomical logic of smell
The sense of smell is essential for almost all animals. It helps find food, detect dangers, and distinguish between friends and enemies. As the saying goes: You really get up my nose.
Research carried out at Helmholtz Munich has shown that…
Summer School on Chromatin Biology: A hands-on expedition
We are delighted to announce the launch of the "1st Helmholtz Summer School on Chromatin Biology: A hands-on expedition", which will take place at the Neuherberg Campus of Helmholtz Munich, from August 15-26, 2022.
A milestone for developmental biology - Scientists publish the first single-transcriptome of a human gastrulation embryo (Kopie 1)
For the first time, scientists based at Helmholtz Zentrum München and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). Their findings will drive future studies to…
Mitochondrial defects characterize 'loser' cells in cell competition
The work of the Scialdone Lab at the Helmholtz Zentrum München and the Rodriguez at the Imperial College elucidates that differences in mitochondrial activity are key determinants for cellular fitness in various contexts, where endogenous cell…
