Molecular Targets and Therapeutics Center Functional Epigenetics

A recent discovery led by Dr. Anika Seel and Dr. Kurt Schmoller at the Institute for Functional Epigenetics (IFE) at Helmholtz Munich has uncovered a fascinating link between cell size and mitochondrial DNA regulation, shedding light on a previously…

We pay tribute to the loss of a remarkable scientist, Colyn Crane-Robinson, who passed away on 5th March 2023. Throughout his lifetime, Colyn's unwavering dedication and infectious enthusiasm enriched our understanding of nucleic acid structures and…

Join us at the Munich Epigenetics Spotlight Meeting 16.10.23!

We will have talks selected from the abstracts, flash talks and 2 invited speakers - secure you spot now!

The IUBMB Focused Meeting on Integrative Omics of Nuclear Functions co-organized by Dr. Till Bartke from the Institute of Functional Epigenetics will take place in Crete (Greece) on October 15-20, 2023.

In a cross-departmental collaboration with the Institute for Diabetes and Cancer (IDC) and the Institute of Virology (Viro), researchers from the Schneider lab (Institute of Functional Epigenetics, IFE) have discovered a novel axis connecting…

The analysis of single-cell RNA-sequencing data is a powerful tool for identifying new types of cells. However, the rarer the cells are, the more challenging it becomes to find and characterize them. This means that rare cells can often go unnoticed,…

The Paris-Munich Epigenetics Workshop & Symposium organized by Dr. Till Bartke from the Institute of Functional Epigenetics will take place at the Max Planck Institute of Biochemistry in Munich on June 14-16, 2023.

The Gordon Research Conference "Chromatin Modifications in Health and Disease", co-organised by Robert Schneider, will take place from June 11-16,2023, at Bryant University in Rhode Island. The deadline for abstract submission is on May 14, 2023.

In the perspective article "In preprints: improving and interrogating embryo models", Antonio Scialdone from the Institute for Epigenetics and Stem Cells, the Institute of Functional Epigenetics, and the Institute of Computational Biology at…

When a cell divides, the correct distribution of cellular content, such as RNAs, to daughter cells is essential. By tagging RNAs with the new diSpinach aptamer in combination with a self-made microfluidics device, researchers at the Institute of…

Inspired by recent work from Antonio Scialdone’s group on the spatial expression of olfactory neurons, Maria Elena Torres Padilla and Robert Schneider, directors of IES and IFE respectively, teamed up with the Deutsches Museum to share our research…

The first 'Helmholtz Summer School on Chromatin Biology: A hands-on-expedition', organized by the Institute of Epigenetics and Stem Cells (IES) and the Institute of Functional Epigenetics (IFE) in collaboration with Abcam, took place on Campus from…

Since 2016, the annual Summer Internship Program in Epigenetics, Stem Cells, and Artificial Intelligence gives international students the opportunity to work alongside world-leading scientists on original research. Under the supervision of Kurt…

Even though deep learning has led to improvements, the downstream analysis of live-cell microscopy images remains a bottleneck. Recently, researchers from the Institute of Functional Epigenetics published their open-source and user-friendly software…

As part of the book series ‘Methods in Molecular Biology’, Springer Nature has released the methods and protocols collection ‘Histone Methyltransferases’. The chapter contributed by Till Bartke and colleagues from the Institute of Functional…

Experts from academia and the pharmaceutical industry came together at “The Biological Methylation Conference: Fundamental Mechanism in Human Health and Disease” in Catania to share new exciting results about protein and RNA methylations as well as…

Over the last 60 years, research has shed light on histone PTMs and their role in all DNA-templated processes. In the last decade, novel methodologies, such as genome-wide sequencing approaches, have paved the way toward understanding how their…

Just as we use Google Maps, cells rely on gradient sensing of signal molecules to reach their destination. However, in their case, the destination is the source of the attractant and not the restaurant of choice. Using mathematical models,…

The sense of smell is essential for almost all animals. It helps find food, detect dangers, and distinguish between friends and enemies. As the saying goes: You really get up my nose.

Research carried out at Helmholtz Munich has shown that…

Article in Nature Communications: Reduction of PRMT7 protein could stop tissue damage

We are delighted to announce the launch of the "1st Helmholtz Summer School on Chromatin Biology: A hands-on expedition", which will take place at the Neuherberg Campus of Helmholtz Munich, from August 15-26, 2022.

For the first time, scientists based at Helmholtz Munich and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). The finding, published in the journal Nature, will…

For the first time, scientists based at Helmholtz Zentrum München and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). Their findings will drive future studies to…

The work of the Scialdone Lab at the Helmholtz Zentrum München and the Rodriguez at the Imperial College elucidates that differences in mitochondrial activity are key determinants for cellular fitness in various contexts, where endogenous cell…

Cellular competition is a crucial quality control process that ensures that the development of an organism relies on healthy cells. Researchers revealed the secrets underlying cell competition and what features can pre-determine whether a cell will…

After a rigorous peer review process, the board of trustees of Academia Europeae, the pan-European academy of science, humanities and letters, has elected the Stem Cell expert Maria-Elena Torres-Padilla as well as the Epigenetics expert Robert…