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Siarhei -

Computational Health Center Institute of Translational Genomics (ITG)

We generate insights from big biomedical data to improve human health.

We generate insights from big biomedical data to improve human health.

Scientific Focus

Our research leverages big data in genetics and genomics for medically important human traits. We aim to translate insights from genomics into mechanisms of disease development and progression, shortening the path to translation and empowering precision medicine.

Our overarching aims are to

  • Characterise the genetic architecture of common complex diseases of high public health burden;
  • Generate insights into the biological mechanisms underpinning chronic disease development and progression;
  • Develop robust methods for integrating big data to address key biomedical challenges;
  • Catalyse pathways to translation for disease prognosis, management and treatment.

Research Groups

Zeggini Group

We aim to empower precision medicine by translating insights from big biomedical data.

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Wang Sattler Group

We aim to improve personalized healthcare by integrating OMICs data using statistical, bioinformatical and machine learning approaches.

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Kotlarz Group

The mission of our research group is to explore the molecular causes in children with very early onset inflammatory bowel disease (VEO-IBD), a life-threatening condition

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Principal Investigators at ITG

Eleftheria Zeggini

Director, Institute of Translational Genomics View profile

Gabi Kastenmüller

Head of Research Group Systems Metabolomics View profile


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Networks and Affiliations


ITG office