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A study led by Dr. Caspar Ohnmacht from the Center of Allergy and Environment (ZAUM) and Prof. Dietmar Zehn from the Technical University of Munich has provided new insights into how gut bacteria – collectively known as the microbiome – shape the…
A new study, led by Prof. Eleftheria Zeggini, Director of the Institute of Translational Genomics at Helmholtz Munich, and Prof. Anette-Gabriele Ziegler, Director of the Institute of Diabetes Research at Helmholtz Munich, has revealed a significant…
In a new study, researchers at Helmholtz Munich, in collaboration with the Helmholtz Protein Expression and Purification Platform (PEPP), have developed a CRISPR-based technology that activates genes without using DNA or viruses. This method offers a…
Scientists from the German Mouse Clinic at the Institute of Experimental Genetics (Helmholtz Munich) have studied the effects of a missing gene, Ten1, on aging. By generating a mouse model with Ten1 deficiency, researchers observed that without this…
A new study has identified KLK7, a protein found in immune cells, as a key driver of obesity-related inflammation and metabolic disorders. Led by PD Dr. John Heiker and Dr. Aleix Ribas-Latre from the Helmholtz Institute for Metabolic, Obesity and…
Helmholtz Munich researchers have introduced a new imaging method that exploits light, sound, and temperature-induced material changes. This approach uncovers a novel contrast mechanism in optoacoustic imaging, driven by tiny temperature-based shifts…
A study led by researchers from Helmholtz Munich and the German Center for Diabetes Research (DZD) unveils a key communication pathway between the immune system and metabolism in the hypothalamic region of the brain. By identifying the role of…
A study led by Dr. Janna Nawroth, PI at the Pioneer Campus at Helmholtz Munich, unveils key differences between human and rodent airways, redefining models for respiratory research. By mapping mucociliary clearance (MCC) function and refining in…
A research team led by Dr. Eva Hörmanseder from the Institute of Epigenetics and Stem Cells (IES) has uncovered crucial factors that limit the success of nuclear reprogramming, a process used to change one type of cell into another. While this…
A study led by Dr. Tingying Peng, Helmholtz AI PI at the Computational Health Center at Helmholtz Munich, and Dr. Melanie Boxberg from the TUM Department of Pathology has introduced a new technology aimed at improving how doctors analyze tissue…
A research team led by Prof. Henrik Semb, Director of the Institute of Translational Stem Cell Research at Helmholtz Munich, has gained new insights into how immature pancreatic cells decide whether to become insulin-producing beta cells or…
A team of researchers led by Prof. Maria-Elena Torres-Padilla has identified a new factor that plays a crucial role in regulating retrotransposons and genes at the earliest stages of embryonic development. This discovery sheds new light on the moment…
Machine learning is transforming the study of human health, offering deep insights into individual cell behavior. Building on existing knowledge that biases in machine learning can impact fairness and accuracy, a new study, led by Theresa Willem, AI…
The clinical onset of type 1 diabetes is preceded by presymptomatic stages, that are marked by the presence of two or more islet autoantibodies. Stage 1 is characterized by normal blood glucose levels, while stage 2 is marked by dysglycemia. However,…
A research team led by Dr. Malte Lücken from the Institute of Computational Biology (ICB) and the Institute of Lung Health & Immunity (LHI) at Helmholtz Munich has published a guide in Nature Methods on creating single-cell atlases—critical tools for…
A team led by Prof. Fabian Theis, Director of the Computational Health Center and the Institute of Computational Biology at Helmholtz Munich, has developed Spapros, a computational pipeline set to transform the design of spatial transcriptomics…
Lung diseases, including asthma and emphysema, often preferentially affect specific regions of the lung, highlighting the need for precise drug delivery to achieve effective treatment. A team led by Dr. Lin Yang and Dr. Otmar Schmid from the…
Researchers at Helmholtz Munich have identified a specific redox protein as a critical regulator of ferroptosis - a form of regulated oxidative cell death. Research into ferroptosis mechanisms has attracted considerable interest due to its potential…
A new computational tool called Moslin is gaining attention in biomedical research by helping scientists better understand how cells make decisions during critical biological processes like development, disease progression, and tissue healing. The…
A team of researchers has unveiled Tumoroscope, a computational method that offers unprecedented insight into the spatial evolution of tumors and the intricate behaviors of cancer cell populations, known as clones. Published in Nature Communications,…
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