Featured Publications

Featured Publication, HI-MAG, August 28, 2024

A team of researchers at the Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of Helmholtz Munich in Leipzig and the University of Leipzig has uncovered a significant connection between the concentration of salivary…

New hope for acute leukemia patients: Helmholtz Munich researchers, led by Prof. Irmela Jeremias, have identified a promising therapeutic target, ADAM10, which could improve treatment strategies for relapsed leukemia. Their study, recently published…

Featured Publication, Health AI, Pioneer Campus, July 29, 2024

A study led by Lara Urban, Principal Investigator at Helmholtz AI and the Pioneer Campus at Helmholtz Munich and TUM Junior Fellow at the Technical University of Munich (TUM), has revealed a novel method for detecting hidden antibiotic resistance,…

Researchers around Prof. Fabian Theis from Helmholtz Munich and the Technical University of Munich (TUM), have developed CellRank 2, a new tool that promises to transform the way scientists study cells. This new method significantly improves our…

Featured Publication, Molecular Targets and Therapeutics, VIRO, July 25, 2024

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus-infected cells but are inactive. An international team led by scientists at the Technical University of Munich and Helmholtz Munich has discovered that cells…

For newcomers to the field of single-cell analysis as well as for experts, scientists led by Fabian Theis, Head of the Computational Health Center at Helmholtz Munich and Professor at the Technical University of Munich (TUM), developed best practice…

Featured Publication, ICB, July 17, 2024

The technological progress for single-cell research resulted in an increasing amount of data, accordingly big data has become one of the central parts in medical research. “Omics” technologies do not just rely on large scale molecular datasets but…

A new evaluation of data from children with early-stage type 1 diabetes during the COVID-19 pandemic shows an accelerated progression from the presymptomatic early stage to clinical onset of type 1 diabetes in children with a SARS-CoV-2 infection.…

Featured Publication, IDR, July 10, 2024

Islet autoimmunity, which underlies the development of type 1 diabetes (T1D), is influenced by various environmental factors, including early childhood viral infections. Scientists from the GPPAD consortium, coordinated at Helmholtz Munich, recently…

People with prediabetes are advised to reduce their weight in order to prevent manifest diabetes. Researchers from the Institute for Diabetes Research and Metabolic Diseases of Helmholtz Munich at the University of Tübingen, a partner in the German…

Featured Publication, Pioneer Campus, June 17, 2024

A recent review published in Current Opinion in Cell Biology, authored by Jonathan Schneider and Dr. Marion Jasnin from the Helmholtz Pioneer Campus at Helmholtz Munich, illuminates the capabilities of cryo-electron tomography (cryo-ET) in unraveling…

A team led by Prof. Fabian Theis developed HADGE, a new tool that improves the accuracy and efficiency of identifying individual donors in single-cell studies. The work, recently published in Genome Biology, represents a major step forward in the…

Featured Publication, IES, June 10, 2024

A new paper published in Developmental Cell is the result of a collaboration between the Scialdone (Helmholtz Munich) and Srinivas (Oxford) groups. The two teams combined their respective experimental and computational expertise to unravel the…

The diagnosis of type 1 diabetes often comes with serious complications for families, as the autoimmune disease is frequently detected only after severe symptoms develop. Early detection of type 1 diabetes through population-wide screening offers…

Featured Publication, Molecular Targets and Therapeutics, STB, June 07, 2024

Researchers created a new approach to reduce the complexity of the NMR experiments and facilitate the investigation of membrane protein systems of pharmaceutical importance.

The rise in asthma has been linked to different environmental and lifestyle factors including dietary habits. Researchers at Helmholtz Munich now discovered that a higher salt intake contributes to allergic asthma incidence in females. The team…

Featured Publication, Pioneer Campus, May 22, 2024

Helmholtz Munich researcher Celia Martinez-Jimenez, principal investigator at the Pioneer Campus in the research group “Molecular Ageing”, and her team have unraveled the enigmatic world of hepatocyte polyploidy—a genomic phenomenon that proved to…

Featured Publication, IDC, May 14, 2024

A new study found that hypertension patients who took their blood pressure medication at a time aligned with their body clock had a reduced risk of heart attack.

Featured Publication, STB, May 10, 2024

A team led by Helmholtz Munich scientist Dr. Grzegorz Popowicz unveils the Molecular Interactions Structurally Optimized (MISATO) dataset, offering a transformative approach to training AI models for designing new drug molecules. MISATO represents a…

Featured Publication, April 29, 2024

A team of Helmholtz Munich scientists has made a significant advancement in the understanding of ferroptosis, a complex form of cell death, by successfully detecting it retrospectively in human pathological conditions. This pioneering research,…

Featured

Publications

The Concentration of Salivary Extracellular Vesicles Is Related to Obesity

ADAM10: A New Precision Target for Acute Leukemia Therapy

Detecting Hidden Antibiotic Resistance With Real-Time-Genomics

Advancing Single-Cell Analysis With CellRank 2

Hepatitis B: Liver cells switch off the immune response

Single-Cell Analysis: Best Practice Guidelines

Open Source Consortium for Single-Cell Analysis

COVID-19 Pandemic Accelerates Onset of Clinical Type 1 Diabetes

Insights From the COVID-19 Pandemic: Change in Infection History and Islet Autoimmunity Incidence

Optimum Protection Against Diabetes: Weight Loss Plus Remission of Prediabetes

Cryo-ET Sheds Light on Inner Working of Cells

New Tool Enhances Single-Cell Research Accuracy

New paper unravels the molecular mechanisms underlying a key event which lays down the anatomical foundation of the body

Population-Wide Screening for Early-Stage Type 1 Diabetes in Children: Opportunities and Challenges in Pediatric Care

New method to investigate the structure and dynamics of challenging membrane proteins

Does A High-Salt Diet Trigger Asthma?

Decoding Liver Cells: Hepatocyte Polyploidy Emerges as Vital Shield Against Aging

Patient Chronotype Could Impact Best Time to Take Blood Pressure Medication

MISATO Dataset: Transforming Drug Discovery with AI

Unraveling Ferroptosis: Tracing Back Cell Death in Human Pathology

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