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Featured Publication, Diabetes, HI-MAG,

How Diet and Cold Rewire Brown Fat at the Epigenetic Level

A team of researchers from the Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG), an institute of Helmholtz Munich at the Leipzig University, in collaboration with the University Hospital of Leipzig Medical Center and the…

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Featured Publication, Computational Health, ICB,

Mapping Carotid Artery Plaques at Single-Cell Resolution

Researchers from Helmholtz Munich, the Technical University of Munich (TUM), and international partner institutions have generated one of the most detailed cellular maps of carotid artery plaques to date. Their work shows how different cell types and…

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Featured Publication, Diabetes, HI-MAG,

New "Cool-Down" Hormone Found: Vaspin Slows the Body’s Heat-Producing Fat

A research team at Helmholtz Munich has uncovered a previously unknown “cool-down” signal within body fat. Led by PD Dr. John Heiker and Inka Rapöhn from the Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) at Helmholtz…

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Featured Publication, Computational Health, ITG,

Tracking Metabolic Clues Years Before Type 2 Diabetes Develops

Researchers at Helmholtz Munich have found that the body begins signaling the risk of type 2 diabetes many years before the disease is diagnosed. In a long-term study, the team examined hundreds of blood metabolites – small molecules that reflect…

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Featured Publication, Molecular Targets and Therapeutics, SAT,

Fine-Tuning Immunity: The Role of Ubiquitination in T cell Activation

A new study reveals how two key molecular players – the linear ubiquitin chain assembly complex (LUBAC) and TRAF6 – work together to fine-tune immune signaling in T cells. Published in Nature Communications, the research from the group of Prof.…

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Featured Publication, Computational Health, Health AI,

TITAN: A Multimodal AI Model for Digital Pathology Slides

Scientists at Helmholtz Munich, together with Harvard Medical School and international collaborators, have developed TITAN, an artificial intelligence (AI) model capable of analyzing and describing digital pathology slides. By combining information…