Munich Epigenetics Spotlight Meeting 2024: October 23rd
8th Edition: October 23rd, 20248th Munich Epigenetics Spotlight Meeting
On Wednesday, October 23rd 2024, Dr. Maria Elena Torres-Padilla (Director, IES) and Dr. Robert Schneider (Director, IFE) invited fellow researchers from the Munich Epigenetics Community to the 8th Munich Epigenetic Spotlight Meeting at Helmholtz Munich. This meeting is a great opportunity to discuss recent exciting findings in chromatin biology, histone and DNA/RNA modifications, and mechanisms of different epigenetic phenomena, from and with, the local Epigenetics Community.
Registrations are always FREE but mandatory to attend the event for logistics purposes.
2024 Keynote Speakers
Dr. Mounia Lagha
(Institut de Génétique Moléculaire de Montpellier, Montpellier, France)
Lighting up the central dogma to dissect how sharp developmental patterns are established
A fundamental question in biology is how cellular processes are so reproducible despite the inherent variations in the chemical reactions governing them. During development of a multicellular organism, precise control of gene expression allows the reproducible establishment of patterns. Our goal is to elucidate the mechanisms responsible for precision in gene expression and to link them to accuracy in cell fate decisions.
My team tackles this question using the early development of Drosophila as a model system, during the maternal to zygotic transition. During this critical developmental window, patterns of gene expression are rapidly established with remarkable reproducibility and accuracy. We use quantitative imaging, genetic manipulations, biophysics and mathematical modeling to integrate the dynamic aspects of transcription and translation and examine how they contribute to cell fate decisions.
Dr. Frédéric Berger
(Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Vienna, Austria)
Meiosis achieves epigenetic reprogramming independently of gametogenesis and fertilization
Around the time of fertilization and early embryogenesis, the epigenetic marks of the parental genomes are reprogrammed to produce the new chromatin landscape of the progeny. In most animals and plants, fertilization and early embryogenesis are tightly coupled to meiosis.
To address the question of whether epigenetic reprogramming occurs specifically during meiosis, here we studied the liverwort Marchantia polymorpha in which meiosis is entirely separate in time and space from fertilization and embryogenesis. In Marchantia, we show that epigenetic marks are reshuffled over the course of meiosis. This is followed by the establishment of the epigenetic landscape that governs vegetative plant development after germination of meiotic spores. Thus, meiosis is central to epigenetic reprogramming in Marchantia and we propose this is a common feature of species that undergo sexual reproduction.
Presentations
Additional to the Keynote speakers, senior PhD students and Postdocs from the local Epigenetics Community are invited to present their work in front of the expert audience and apply for one of the four presentation slots (15min presentation +10min Q&A).
Venue
Stem Cell Center, hosted by the Institute of Epigenetics and Stem Cells (IES) at Helmholtz Zentrum Munich
(Marchioninistraße 25, 81377, Munich (Germany))
To get there by public transport, stop at Großhadern U-bahn station (U6 line) and walk to the IES.
Date
October 23rd, 2024 (14 - 19h)
Spread the news and share the event (download the Poster).
8th Munich Epigenetics Spotlight Meeting
On Wednesday, October 23rd 2024, Dr. Maria Elena Torres-Padilla (Director, IES) and Dr. Robert Schneider (Director, IFE) invited fellow researchers from the Munich Epigenetics Community to the 8th Munich Epigenetic Spotlight Meeting at Helmholtz Munich. This meeting is a great opportunity to discuss recent exciting findings in chromatin biology, histone and DNA/RNA modifications, and mechanisms of different epigenetic phenomena, from and with, the local Epigenetics Community.
Registrations are always FREE but mandatory to attend the event for logistics purposes.
2024 Keynote Speakers
Dr. Mounia Lagha
(Institut de Génétique Moléculaire de Montpellier, Montpellier, France)
Lighting up the central dogma to dissect how sharp developmental patterns are established
A fundamental question in biology is how cellular processes are so reproducible despite the inherent variations in the chemical reactions governing them. During development of a multicellular organism, precise control of gene expression allows the reproducible establishment of patterns. Our goal is to elucidate the mechanisms responsible for precision in gene expression and to link them to accuracy in cell fate decisions.
My team tackles this question using the early development of Drosophila as a model system, during the maternal to zygotic transition. During this critical developmental window, patterns of gene expression are rapidly established with remarkable reproducibility and accuracy. We use quantitative imaging, genetic manipulations, biophysics and mathematical modeling to integrate the dynamic aspects of transcription and translation and examine how they contribute to cell fate decisions.
Dr. Frédéric Berger
(Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Vienna, Austria)
Meiosis achieves epigenetic reprogramming independently of gametogenesis and fertilization
Around the time of fertilization and early embryogenesis, the epigenetic marks of the parental genomes are reprogrammed to produce the new chromatin landscape of the progeny. In most animals and plants, fertilization and early embryogenesis are tightly coupled to meiosis.
To address the question of whether epigenetic reprogramming occurs specifically during meiosis, here we studied the liverwort Marchantia polymorpha in which meiosis is entirely separate in time and space from fertilization and embryogenesis. In Marchantia, we show that epigenetic marks are reshuffled over the course of meiosis. This is followed by the establishment of the epigenetic landscape that governs vegetative plant development after germination of meiotic spores. Thus, meiosis is central to epigenetic reprogramming in Marchantia and we propose this is a common feature of species that undergo sexual reproduction.
Presentations
Additional to the Keynote speakers, senior PhD students and Postdocs from the local Epigenetics Community are invited to present their work in front of the expert audience and apply for one of the four presentation slots (15min presentation +10min Q&A).
Venue
Stem Cell Center, hosted by the Institute of Epigenetics and Stem Cells (IES) at Helmholtz Zentrum Munich
(Marchioninistraße 25, 81377, Munich (Germany))
To get there by public transport, stop at Großhadern U-bahn station (U6 line) and walk to the IES.
Date
October 23rd, 2024 (14 - 19h)
Spread the news and share the event (download the Poster).
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